PE20081301A1 - Tabletas de bi-capa de estrogeno/moduladores selectivos de receptores de estrogeno (serm) y estrogeno/progestina - Google Patents
Tabletas de bi-capa de estrogeno/moduladores selectivos de receptores de estrogeno (serm) y estrogeno/progestinaInfo
- Publication number
- PE20081301A1 PE20081301A1 PE2007001673A PE2007001673A PE20081301A1 PE 20081301 A1 PE20081301 A1 PE 20081301A1 PE 2007001673 A PE2007001673 A PE 2007001673A PE 2007001673 A PE2007001673 A PE 2007001673A PE 20081301 A1 PE20081301 A1 PE 20081301A1
- Authority
- PE
- Peru
- Prior art keywords
- estrogen
- layer
- serm
- progestin
- receptor modulators
- Prior art date
Links
- 239000000262 estrogen Substances 0.000 title abstract 3
- 229940011871 estrogen Drugs 0.000 title abstract 3
- 239000000583 progesterone congener Substances 0.000 title abstract 2
- 239000000333 selective estrogen receptor modulator Substances 0.000 title 2
- 229940095743 selective estrogen receptor modulator Drugs 0.000 title 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 102000015694 estrogen receptors Human genes 0.000 abstract 1
- 108010038795 estrogen receptors Proteins 0.000 abstract 1
- 238000009164 estrogen replacement therapy Methods 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229960002985 medroxyprogesterone acetate Drugs 0.000 abstract 1
- PSGAAPLEWMOORI-PEINSRQWSA-N medroxyprogesterone acetate Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@](OC(C)=O)(C(C)=O)CC[C@H]21 PSGAAPLEWMOORI-PEINSRQWSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A TABLETAS DE BICAPA CARACTERIZADO POR QUE COMPRENDE: (a) UNA PRIMERA CAPA QUE COMPRENDE UN ESTROGENO DESDE 20% HASTA 45% DEL PESO DE LA TABLETA ; (b) UNA SEGUNDA CAPA QUE COMPRENDE UN MODULADOR SELECTIVO DEL RECEPTOR ESTROGENO Y UN AGENTE PROGESTACIONAL DESDE 55% HASTA 80% DEL PESO DE LA TABLETA SELECCIONADO DE ACETATO DE MEDROXIPROGESTERONA Y 1-[4-(2-AZEPAN-1-IL-ETOXI)-BENCIL]-2-(4-HIDROXI-FENIL)-3-METIL-1H-INDOL-5-OL. COMPRENDE ADEMAS UN COMPONENTE POLIMEIRICO QUE FORMA GEL HIDROFILICO TAL COMO HIDROXIPROPILMETILCELULOSA. SE REFIERE TAMBIEN A COMPOSICIONES FARMACEUTICAS Y UN PROCEDIMIENTO DE PREPARACION. DICHAS TABLETAS SON UTILES PARA MINIMIZAR EFECTOS COLATERALES DE ERT( TERAPIA DE REEMPLAZO DE ESTROGENO); GRACIAS A LA DOSIFICACION UNICA LA CUAL PUEDE SUMINISTRAR MULTIPLES FARMACOS A DIFERENTES VELOCIDADES DE LIBERACION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86771506P | 2006-11-29 | 2006-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20081301A1 true PE20081301A1 (es) | 2008-10-01 |
Family
ID=39456367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007001673A PE20081301A1 (es) | 2006-11-29 | 2007-11-28 | Tabletas de bi-capa de estrogeno/moduladores selectivos de receptores de estrogeno (serm) y estrogeno/progestina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20080175905A1 (es) |
| EP (1) | EP2086550A2 (es) |
| JP (1) | JP2010511062A (es) |
| KR (1) | KR20090086100A (es) |
| CN (1) | CN101541326A (es) |
| AR (1) | AR064014A1 (es) |
| AU (1) | AU2007325207A1 (es) |
| BR (1) | BRPI0719675A2 (es) |
| CA (1) | CA2670544A1 (es) |
| CL (1) | CL2007003429A1 (es) |
| IL (1) | IL198823A0 (es) |
| MX (1) | MX2009005724A (es) |
| PE (1) | PE20081301A1 (es) |
| RU (1) | RU2009117201A (es) |
| TW (1) | TW200831139A (es) |
| WO (1) | WO2008067387A2 (es) |
| ZA (1) | ZA200903725B (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0806543A2 (pt) * | 2007-01-12 | 2014-04-22 | Wyeth Corp | Composições de comprimido em comprimido |
| US20090324714A1 (en) * | 2008-06-27 | 2009-12-31 | Wyeth | Dual adhesive technology |
| EP2493477B1 (en) * | 2009-10-27 | 2013-10-16 | Wyeth LLC | Bazedoxifene formulations with antioxidants |
| US8501690B2 (en) | 2010-04-30 | 2013-08-06 | John G. Stark | Use of selective estrogen receptor modulator for joint fusion and other repair or healing of connective tissue |
| WO2012120365A1 (en) | 2011-03-07 | 2012-09-13 | Aurobindo Pharma Limited | Stable pharmaceutical composition comprising ethinyl estradiol |
| CA2835979C (en) | 2011-06-01 | 2018-05-01 | Estetra S.A. | Process for the production of estetrol intermediates |
| HRP20160692T2 (hr) | 2011-06-01 | 2016-09-23 | Estetra S.P.R.L. | Postupak za proizvodnju intermedijera estetrola |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| EA026664B1 (ru) * | 2011-11-04 | 2017-05-31 | Эджайл Терапьютикс, Инк. | Композиция и устройство для трансдермальной доставки прогестина |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| HRP20211377T1 (hr) | 2011-11-23 | 2022-01-07 | Therapeuticsmd, Inc. | Prirodne kombinirane hormonske supstitucijske formulacije i terapije |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| PT3079671T (pt) * | 2013-12-12 | 2017-11-24 | Donesta Bioscience B V | Resumo |
| WO2015179782A1 (en) | 2014-05-22 | 2015-11-26 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CA2951284A1 (en) | 2014-07-29 | 2016-02-04 | Therapeuticsmd, Inc. | Transdermal cream |
| HRP20210555T1 (hr) | 2015-06-18 | 2021-05-14 | Estetra Sprl | Orodisperzibilna tableta koja sadrži estetrol |
| CA2988498C (en) | 2015-06-18 | 2022-02-08 | Mithra Pharmaceuticals S.A. | Orodispersible dosage unit containing an estetrol component |
| BR112017027229B1 (pt) | 2015-06-18 | 2023-12-05 | Estetra Sprl | Grânulos contendo estetrol secos, unidade de dosagem compreendendo grânulos, processo de preparação e seus usos |
| PT3310345T (pt) | 2015-06-18 | 2021-05-28 | Estetra Sprl | Comprimido orodispersível contendo estetrol |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| MX2018011705A (es) | 2016-04-01 | 2019-06-10 | Therapeuticsmd Inc | Composicion farmaceutica de hormona esteroide. |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| KR102712911B1 (ko) | 2016-08-05 | 2024-10-04 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| WO1997004752A1 (en) * | 1995-07-26 | 1997-02-13 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions of conjugated estrogens and methods for their use |
| US5998402A (en) * | 1996-04-19 | 1999-12-07 | American Home Products Corporation | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents |
| US6479535B1 (en) * | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
| US20010034340A1 (en) * | 2000-03-20 | 2001-10-25 | American Home Products Corporation | Hormone replacement therapy |
| JP2005526083A (ja) * | 2002-03-14 | 2005-09-02 | ワトソン ファーマシューティカルズ， インコーポレイテッド | プロゲステロンの経口薬物送達システム |
| UA85374C2 (en) * | 2002-06-13 | 2009-01-26 | Уайт | bazedoxifene treatment regimen |
| EP1753407B1 (en) * | 2004-06-07 | 2017-03-08 | Wyeth LLC | Sugar coatings and methods therefor |
| MX2007012167A (es) * | 2005-03-31 | 2007-11-22 | Wyeth Corp | Producto de combinacion de o-desmetilvenlafaxina y bazedoxifeno, y usos del mismo. |
| CN101252921A (zh) * | 2005-06-29 | 2008-08-27 | 惠氏公司 | 轭合雌激素类物质和苯卓昔芬的制剂 |
| MX2009004960A (es) * | 2006-11-07 | 2009-06-05 | Wyeth Corp | Revestimientos de azucar y metodos para los mismos. |
-
2007
- 2007-11-28 EP EP07871621A patent/EP2086550A2/en not_active Withdrawn
- 2007-11-28 CN CNA2007800441214A patent/CN101541326A/zh active Pending
- 2007-11-28 AU AU2007325207A patent/AU2007325207A1/en not_active Abandoned
- 2007-11-28 AR ARP070105286A patent/AR064014A1/es unknown
- 2007-11-28 MX MX2009005724A patent/MX2009005724A/es unknown
- 2007-11-28 PE PE2007001673A patent/PE20081301A1/es not_active Application Discontinuation
- 2007-11-28 US US11/946,586 patent/US20080175905A1/en not_active Abandoned
- 2007-11-28 RU RU2009117201/15A patent/RU2009117201A/ru not_active Application Discontinuation
- 2007-11-28 TW TW096145178A patent/TW200831139A/zh unknown
- 2007-11-28 BR BRPI0719675-0A2A patent/BRPI0719675A2/pt not_active Application Discontinuation
- 2007-11-28 CL CL200703429A patent/CL2007003429A1/es unknown
- 2007-11-28 JP JP2009539461A patent/JP2010511062A/ja not_active Withdrawn
- 2007-11-28 WO PCT/US2007/085773 patent/WO2008067387A2/en not_active Ceased
- 2007-11-28 KR KR1020097012025A patent/KR20090086100A/ko not_active Withdrawn
- 2007-11-28 CA CA002670544A patent/CA2670544A1/en not_active Abandoned
-
2009
- 2009-05-19 IL IL198823A patent/IL198823A0/en unknown
- 2009-05-28 ZA ZA200903725A patent/ZA200903725B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010511062A (ja) | 2010-04-08 |
| CL2007003429A1 (es) | 2008-04-11 |
| AR064014A1 (es) | 2009-03-04 |
| RU2009117201A (ru) | 2011-01-10 |
| CA2670544A1 (en) | 2008-06-05 |
| US20080175905A1 (en) | 2008-07-24 |
| CN101541326A (zh) | 2009-09-23 |
| KR20090086100A (ko) | 2009-08-10 |
| BRPI0719675A2 (pt) | 2013-12-24 |
| EP2086550A2 (en) | 2009-08-12 |
| IL198823A0 (en) | 2010-02-17 |
| TW200831139A (en) | 2008-08-01 |
| MX2009005724A (es) | 2009-06-12 |
| WO2008067387A2 (en) | 2008-06-05 |
| AU2007325207A1 (en) | 2008-06-05 |
| ZA200903725B (en) | 2010-04-28 |
| WO2008067387A3 (en) | 2008-08-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20081301A1 (es) | Tabletas de bi-capa de estrogeno/moduladores selectivos de receptores de estrogeno (serm) y estrogeno/progestina | |
| CY1123162T1 (el) | Ελεγχομενης αποδεσμευσης φαρμακευτικα σκευασματα νιταζοξανιδης | |
| PE20081632A1 (es) | Composiciones de tableta en tableta | |
| BRPI0516830A (pt) | composições de droga de liberação sustentada convenientemente implantáveis | |
| NZ589437A (en) | Immediate release tablet comprising 5-azacytidine and a non-enteric coating applied with an ethanol solvent | |
| CO6400186A2 (es) | Tabletas de acetato de ulipristal | |
| MX391854B (es) | Formulaciones farmaceuticas que contienen hidrato de propilenglicol de dapagliflozina | |
| CL2011000935A1 (es) | Composicion farmaceutica que comprende acetaminofeno y un material de tramadol complejo, que exhibe una liberacion sostenida y coordinada a traves de una capa de liberacion sostenida y otra de liberacion inmediata; metodo de preparacion;y el uso de un material complejo de tramadol y acetaminofeno para preparar un medicamento para el tratamiento del dolor. | |
| AR078846A1 (es) | Composicion para el tratamiento de la enfermedad de alzheimer | |
| MX2009010289A (es) | Composiciones para administracion nasal. | |
| AR069875A1 (es) | Composiciones de temazepam para tabletas de desintegracion oral y metodo de preparacion | |
| WO2010100506A3 (en) | Delivery system with scaffolds | |
| ECSP10010224A (es) | Formulaciones líquidas de hormona luteinizante (lh). | |
| AU2010212580A8 (en) | Stable pharmaceutical composition for atherosclerosis | |
| PT2043600T (pt) | Formulações farmacêuticas para a libertação prolongada de princípio(s) ativo(s), assim como suas aplicações, nomeadamente terapêuticas | |
| FR19C1030I1 (fr) | Systeme d'administration de medicament pour administrer des substances pharmaceutiquement actives pauvrement hydrosolubles | |
| WO2010127205A3 (en) | Fixed dose drug combination formulations | |
| MX2012013021A (es) | Formulaciones resistentes a alcohol. | |
| MY160002A (en) | Methods of using and compositions comprising pde4 modulators for treatment, prevention and management of tuberculosis | |
| EP2062579A4 (en) | SOLID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING OPTICALLY STABLE RAMOSETRON | |
| AR066924A1 (es) | Formulacion de nevirapina de liberacion prolongada | |
| FR2931359B1 (fr) | Utilisation d'une matrice pour administration orale de magnesium a liberation prolongee, et composition contenant cette matrice | |
| UY33061A (es) | Composiciones para comprimidos desintegrables oralmente de ondansetrón para prevenir náuseas y vómitos | |
| PL2131823T3 (pl) | Film jednowarstwowy o szybkim rozpadzie do ustnego podawania substancji aktywnych | |
| MXPA06011467A (es) | Combinacion de sustancias activas que comprenden un carbinol combinado con al menos un farmaco antiinflamatorio no esteroideo (nsaid). |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |