PE20080330A1 - Composiciones farmaceuticas para la liberacion sostenida de fenilefrina - Google Patents
Composiciones farmaceuticas para la liberacion sostenida de fenilefrinaInfo
- Publication number
- PE20080330A1 PE20080330A1 PE2007000686A PE2007000686A PE20080330A1 PE 20080330 A1 PE20080330 A1 PE 20080330A1 PE 2007000686 A PE2007000686 A PE 2007000686A PE 2007000686 A PE2007000686 A PE 2007000686A PE 20080330 A1 PE20080330 A1 PE 20080330A1
- Authority
- PE
- Peru
- Prior art keywords
- phenylephrine
- sustained release
- cellulose
- sodium
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 title abstract 2
- 229960001802 phenylephrine Drugs 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- 239000011734 sodium Substances 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052710 silicon Inorganic materials 0.000 abstract 1
- 239000010703 silicon Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA SOLIDA DE LIBERACION SOSTENIDA, QUE COMPRENDE: A) FENILEFRINA EN UNA MATRIZ POLIMERICA HIDROFILICA RESULTANTE DE UNA MEZCLA DE HIDROXIPROPIL METILCELULOSA Y SAL DE CARBOXIMETIL CELULOSA SODICA QUE FORMAN UNA CAPA DE LIBERACION SOSTENIDA, B) EXCIPIENTES COMO POLIVINILPIRROLIDONA, DIOXIDO DE SILICIO, ENTRE OTROS. PUEDEN CONTENER ADEMAS OTROS PRINCIPIOS ACTIVOS DE LIBERACION INMEDIATA COMO UN ANTIHISTAMINICO, ANTIPIRETICO O ANTIINFLAMATORIO NO ESTEROIDEO. DICHA COMPOSICION ES LIBERADA AL FLUIDO GASTROINTESTINAL A UNA VELOCIDAD INDEPENDIENTE DEL pH Y ES UTIL EN EL TRATAMIENTO DE LOS SINTOMAS DEL RESFRIO, GRIPE O ALERGIAS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81001906P | 2006-06-01 | 2006-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080330A1 true PE20080330A1 (es) | 2008-04-25 |
Family
ID=38565616
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007000686A PE20080330A1 (es) | 2006-06-01 | 2007-06-01 | Composiciones farmaceuticas para la liberacion sostenida de fenilefrina |
| PE2011001106A PE20120075A1 (es) | 2006-06-01 | 2007-06-01 | Composiciones farmaceuticas para la liberacion sostenida de fenilefrina |
| PE2015000135A PE20150773A1 (es) | 2006-06-01 | 2007-06-01 | Composiciones farmaceuticas para la liberacion sostenida de fenilefrina |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011001106A PE20120075A1 (es) | 2006-06-01 | 2007-06-01 | Composiciones farmaceuticas para la liberacion sostenida de fenilefrina |
| PE2015000135A PE20150773A1 (es) | 2006-06-01 | 2007-06-01 | Composiciones farmaceuticas para la liberacion sostenida de fenilefrina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070281020A1 (es) |
| EP (1) | EP2029114B1 (es) |
| JP (1) | JP5121824B2 (es) |
| KR (1) | KR101464771B1 (es) |
| CN (2) | CN101505735A (es) |
| AR (1) | AR061166A1 (es) |
| AU (1) | AU2007254826B2 (es) |
| BR (1) | BRPI0711871A2 (es) |
| CA (1) | CA2653955C (es) |
| MX (1) | MX2008015358A (es) |
| NO (1) | NO20085414L (es) |
| PE (3) | PE20080330A1 (es) |
| RU (1) | RU2450803C2 (es) |
| SG (1) | SG172660A1 (es) |
| TW (1) | TWI405567B (es) |
| WO (1) | WO2007143163A2 (es) |
| ZA (1) | ZA200810178B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010014952A2 (en) | 2008-07-31 | 2010-02-04 | Clarke Mosquito Control Products, Inc. | Extended release tablet and method for making and using same |
| TWI394594B (zh) * | 2009-03-06 | 2013-05-01 | China Chemical & Pharmaceutical Co Ltd | 錠劑藥學組成物及其製造方法 |
| US20110104272A1 (en) * | 2009-11-05 | 2011-05-05 | Depomed, Inc. | Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine |
| US20110104273A1 (en) * | 2009-11-05 | 2011-05-05 | Depomed, Inc. | Gastric retentive pharmaceutical compositions for immediate and extended release of phenylephrine |
| BR112012024576A2 (pt) * | 2010-03-31 | 2016-05-31 | Wockhardt Ltd | composição farmacêutica de liberação modificada compreendendo desvenlafaxina ou sais da mesma e processo para preparação da dita composição |
| US20140271893A1 (en) | 2013-03-15 | 2014-09-18 | Mcneil-Ppc, Inc. | Coated phenylephrine particles and use thereof in pharmaceutical formulations |
| US20140271891A1 (en) | 2013-03-15 | 2014-09-18 | Mcneil-Ppc, Inc. | Phenylephrine resinate particles and use thereof in pharmaceutical formulations |
| CN107148268A (zh) | 2014-09-19 | 2017-09-08 | 宝洁公司 | 脉冲释放去氧肾上腺素剂型 |
| MA41152A (fr) | 2014-12-12 | 2017-10-17 | Johnson & Johnson Consumer Inc | Procédé de fabrication de particules de résinate de phényléphrine ; particules de résinate de phényléphrine et utilisation des particules de résinate de phényléphrine dans des formulations pharmaceutiques |
| US10278930B2 (en) | 2017-03-16 | 2019-05-07 | The Procter & Gamble Company | Method for relieving sinus congestion |
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| US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
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| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| AU570306B2 (en) * | 1984-02-15 | 1988-03-10 | Schering Corporation | 8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridine and its salts. |
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| US4623664A (en) * | 1985-10-31 | 1986-11-18 | University Of Iowa Research Foundation | Oil suspended phenylephrine |
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-
2007
- 2007-06-01 CN CNA2007800277845A patent/CN101505735A/zh active Pending
- 2007-06-01 EP EP07795663.9A patent/EP2029114B1/en active Active
- 2007-06-01 BR BRPI0711871-6A patent/BRPI0711871A2/pt not_active IP Right Cessation
- 2007-06-01 PE PE2007000686A patent/PE20080330A1/es not_active Application Discontinuation
- 2007-06-01 CA CA2653955A patent/CA2653955C/en active Active
- 2007-06-01 SG SG2011039831A patent/SG172660A1/en unknown
- 2007-06-01 PE PE2011001106A patent/PE20120075A1/es not_active Application Discontinuation
- 2007-06-01 TW TW096119767A patent/TWI405567B/zh active
- 2007-06-01 CN CN201510086942.0A patent/CN104606163A/zh active Pending
- 2007-06-01 WO PCT/US2007/013056 patent/WO2007143163A2/en not_active Ceased
- 2007-06-01 JP JP2009513322A patent/JP5121824B2/ja active Active
- 2007-06-01 AU AU2007254826A patent/AU2007254826B2/en not_active Ceased
- 2007-06-01 PE PE2015000135A patent/PE20150773A1/es not_active Application Discontinuation
- 2007-06-01 AR ARP070102384A patent/AR061166A1/es not_active Application Discontinuation
- 2007-06-01 US US11/756,774 patent/US20070281020A1/en not_active Abandoned
- 2007-06-01 KR KR1020087031377A patent/KR101464771B1/ko active Active
- 2007-06-01 MX MX2008015358A patent/MX2008015358A/es active IP Right Grant
- 2007-06-01 RU RU2008151946/15A patent/RU2450803C2/ru active
-
2008
- 2008-11-28 ZA ZA2008/10178A patent/ZA200810178B/en unknown
- 2008-12-30 NO NO20085414A patent/NO20085414L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2450803C2 (ru) | 2012-05-20 |
| JP5121824B2 (ja) | 2013-01-16 |
| WO2007143163A2 (en) | 2007-12-13 |
| AU2007254826B2 (en) | 2013-10-24 |
| CA2653955A1 (en) | 2007-12-13 |
| TW200804235A (en) | 2008-01-16 |
| PE20120075A1 (es) | 2012-02-20 |
| NO20085414L (no) | 2008-12-30 |
| SG172660A1 (en) | 2011-07-28 |
| ZA200810178B (en) | 2009-12-30 |
| US20070281020A1 (en) | 2007-12-06 |
| EP2029114A2 (en) | 2009-03-04 |
| CN101505735A (zh) | 2009-08-12 |
| EP2029114B1 (en) | 2014-09-24 |
| AR061166A1 (es) | 2008-08-06 |
| CA2653955C (en) | 2015-10-27 |
| KR20090015990A (ko) | 2009-02-12 |
| CN104606163A (zh) | 2015-05-13 |
| AU2007254826A1 (en) | 2007-12-13 |
| TWI405567B (zh) | 2013-08-21 |
| JP2009538921A (ja) | 2009-11-12 |
| KR101464771B1 (ko) | 2014-11-26 |
| PE20150773A1 (es) | 2015-05-21 |
| WO2007143163A3 (en) | 2008-07-24 |
| BRPI0711871A2 (pt) | 2011-12-06 |
| MX2008015358A (es) | 2009-03-06 |
| RU2008151946A (ru) | 2010-07-20 |
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