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CL2011000625A1 - Preparación sólida que comprende 2-etoxi-1-((2'-(5-oxo-4,5-dihidro-1,2,4-oxadiazol-3-il)bifenil-4-il)metil)-1h-bencimidazol-7-carboxilato de (5-metil-2-oxo-1,3-dioxol-4-il)metilo, un agente regulador de ph y un compuesto antagonista de calcio; y metodos para utilizar y mejorar disolucion del compuesto en la preparacion solida. - Google Patents

Preparación sólida que comprende 2-etoxi-1-((2'-(5-oxo-4,5-dihidro-1,2,4-oxadiazol-3-il)bifenil-4-il)metil)-1h-bencimidazol-7-carboxilato de (5-metil-2-oxo-1,3-dioxol-4-il)metilo, un agente regulador de ph y un compuesto antagonista de calcio; y metodos para utilizar y mejorar disolucion del compuesto en la preparacion solida.

Info

Publication number
CL2011000625A1
CL2011000625A1 CL2011000625A CL2011000625A CL2011000625A1 CL 2011000625 A1 CL2011000625 A1 CL 2011000625A1 CL 2011000625 A CL2011000625 A CL 2011000625A CL 2011000625 A CL2011000625 A CL 2011000625A CL 2011000625 A1 CL2011000625 A1 CL 2011000625A1
Authority
CL
Chile
Prior art keywords
methyl
oxo
solid preparation
compound
benzimidazole
Prior art date
Application number
CL2011000625A
Other languages
English (en)
Inventor
Kazuhiro Hirata
Junya Nomura
Yutaka Tanque
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42059801&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011000625(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of CL2011000625A1 publication Critical patent/CL2011000625A1/es

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    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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Abstract

Composición farmacéutica que comprende a) un compuesto derivado de 1-h-bencimidazol sustituido, b) un agente regulador de PH y c) un compuesto antagonista de calcio; procedimiento de preparación; útil para el tratamiento de enfermedades cardiovasculares.
CL2011000625A 2008-09-25 2011-03-24 Preparación sólida que comprende 2-etoxi-1-((2'-(5-oxo-4,5-dihidro-1,2,4-oxadiazol-3-il)bifenil-4-il)metil)-1h-bencimidazol-7-carboxilato de (5-metil-2-oxo-1,3-dioxol-4-il)metilo, un agente regulador de ph y un compuesto antagonista de calcio; y metodos para utilizar y mejorar disolucion del compuesto en la preparacion solida. CL2011000625A1 (es)

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CR20110209A (es) 2011-05-27
KR20110063557A (ko) 2011-06-10
GEP20146063B (en) 2014-03-25
NZ592225A (en) 2012-06-29
MA32721B1 (fr) 2011-10-02
EP2332535A4 (en) 2013-11-27
US20110229567A1 (en) 2011-09-22
CA2738147C (en) 2016-10-11
US9173849B2 (en) 2015-11-03
ZA201102715B (en) 2012-07-25
AR073380A1 (es) 2010-11-03
CN102223884B (zh) 2015-05-06
UA102271C2 (en) 2013-06-25
EA201170483A1 (ru) 2011-10-31
WO2010035806A1 (ja) 2010-04-01
JPWO2010035806A1 (ja) 2012-02-23
AU2009297522A1 (en) 2010-04-01
MX2011003261A (es) 2011-04-21
ECSP11011001A (es) 2011-05-31
CO6361934A2 (es) 2012-01-20
TW201014850A (en) 2010-04-16
CN102223884A (zh) 2011-10-19
PE20110844A1 (es) 2011-12-05
CN104306975A (zh) 2015-01-28
JP5570426B2 (ja) 2014-08-13
EP2332535A1 (en) 2011-06-15
IL211886A0 (en) 2011-06-30
UY32126A (es) 2010-04-30
CA2738147A1 (en) 2010-04-01

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