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PE20011295A1 - Lente intraocular adaptable inyectable - Google Patents

Lente intraocular adaptable inyectable

Info

Publication number
PE20011295A1
PE20011295A1 PE2001000339A PE2001000339A PE20011295A1 PE 20011295 A1 PE20011295 A1 PE 20011295A1 PE 2001000339 A PE2001000339 A PE 2001000339A PE 2001000339 A PE2001000339 A PE 2001000339A PE 20011295 A1 PE20011295 A1 PE 20011295A1
Authority
PE
Peru
Prior art keywords
adaptable
intraocular lens
polysyloxanes
kpa
composition
Prior art date
Application number
PE2001000339A
Other languages
English (en)
Inventor
Keith Alfred Dillingham
Hendrik Deuring
Laszlo Garamszegi
Hendrik Jan Haitjema
Kenneth Albert Hodd
Jons Gunnar Hilborn
Original Assignee
Pharmacia Groningen Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Groningen Bv filed Critical Pharmacia Groningen Bv
Publication of PE20011295A1 publication Critical patent/PE20011295A1/es

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04Polysiloxanes
    • C08G77/22Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/24Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen halogen-containing groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION OFTALMICA INYECTABLE DE POLISILOXANOS CON POR LO MENOS UN MONOMERO SILOXANO, O DE ARILSILOXANO, CON UN PESO ESPECIFICO APROXIMADAMENTE MAYOR A 1 Y UN INDICE DE REFRACCION ENTRE 1,38 Y 1,60, APROPIADO PARA RESTAURAR LA POTENCIA DE REFRACCION DE LA LENTE NATURAL DEL CRISTALINO Y UNA VISCOSIDAD APROPIADA PARA SER INYECTADO A TRAVES DE UNA CANULA ESTANDAR QUE ES CAPAZ DE FORMAR UNA LENTE INTRAOCULAR ADAPTABLE DESPUES DE SU INYECCION DENTRO DEL SACO CAPSULAR DEL OJO, CARACTERIZADA POR TENER UN MODULO DE YOUNG MENOR A 10 kPa, PREFERIBLEMENTE MENOR A 5 kPa. DONDE EL MONOMERO SILOXANO TIENE LA ESTRUCTURA -RaRbSiO-; SIENDO Ra Y Rb IGUALES O DIFERENTES GRUPOS ALQUILO O FENILO DE LOS CUALES POR LO MENOS UNO SE ENCUENTRA SUSTITUIDO CON UNO O VARIOS ATOMOS DE FLUOR. ASIMISMO, DICHA COMPOSICION PUEDE COMPRENDER TAMBIEN POLISILOXANOS FUNCIONALES CON GRUPOS UNIDOS CAPAZ DE ENTRECRUZAMIENTO, UN AGENTE RETICULANTE Y OPCIONALMENTE UNA CANTIDAD EFECTIVA DE UN CATALIZADOR. SE REFIERE TAMBIEN A UNA LENTE INTRAOCULAR ADAPTABLE QUE SE OBTIENE INYECTANDO LA COMPOSICION DESCRITA DENTRO DEL SACO CAPSULAR DEL OJO
PE2001000339A 2000-04-12 2001-04-11 Lente intraocular adaptable inyectable PE20011295A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0001352A SE0001352D0 (sv) 2000-04-12 2000-04-12 Injectable intraocular accommodating lens

Publications (1)

Publication Number Publication Date
PE20011295A1 true PE20011295A1 (es) 2001-12-25

Family

ID=20279288

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000339A PE20011295A1 (es) 2000-04-12 2001-04-11 Lente intraocular adaptable inyectable

Country Status (14)

Country Link
EP (1) EP1272233B1 (es)
JP (1) JP4979173B2 (es)
KR (1) KR20020093036A (es)
CN (1) CN1292805C (es)
AT (1) ATE303168T1 (es)
AU (2) AU6384801A (es)
CA (1) CA2403516C (es)
CZ (1) CZ20023354A3 (es)
DE (1) DE60113085T2 (es)
HU (1) HUP0300635A2 (es)
IL (2) IL152242A0 (es)
PE (1) PE20011295A1 (es)
SE (1) SE0001352D0 (es)
WO (1) WO2001076651A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ197899A0 (en) 1999-08-02 1999-08-26 Commonwealth Scientific And Industrial Research Organisation Biomedical compositions
SE0201478D0 (sv) 2002-05-16 2002-05-16 Pharmacia & Upjohn Bv Method in eye surgery
US7160324B2 (en) 2002-05-17 2007-01-09 Amo Groningen, B.V. Method in eye surgery
AU2002950469A0 (en) 2002-07-30 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Improved biomedical compositions
EP2193812A1 (en) * 2003-09-19 2010-06-09 Broockeville Corporation N.V. Use of a curable elastomer-precursor for a medical treatment
US7597660B2 (en) 2003-09-19 2009-10-06 Broockeville Corporation B.V. Incontinence therapy
SE0403091D0 (sv) * 2004-12-20 2004-12-20 Amo Groningen Bv New composition for injectable ophtalmic lenses
SE0403092D0 (sv) 2004-12-20 2004-12-20 Amo Groningen Bv Amphiphilic block copolymers and their use
CA2651715C (en) 2006-05-03 2015-03-24 Vision Crc Limited Ocular replacement material production method and the use thereof
GB0711313D0 (en) * 2007-06-11 2007-07-25 Dow Corning A method for making phenylalkylsiloxanes
US10278810B2 (en) 2010-04-29 2019-05-07 Ojo, Llc Injectable physiologically adaptive intraocular lenses (IOL's)
CN103251978A (zh) * 2013-04-18 2013-08-21 温州医学院眼视光研究院 一种可折叠人工晶状体及其制备方法
CN106999507A (zh) * 2014-09-23 2017-08-01 雷恩斯根公司 用于调节人工晶状体的聚合材料
WO2016101025A1 (en) * 2014-12-22 2016-06-30 Brien Holden Vision Institute Compositions and methods for injectable composition for an accommodating intraocular lens
CA3155078A1 (en) * 2019-11-07 2021-05-14 Thomas A. Silvestrini Silicone oil terpolymer for use in intraocular lens devices

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122246A (en) * 1977-09-21 1978-10-24 Dow Corning Corporation Method of preventing discoloration of platinum containing silicone gels
JPS63216574A (ja) * 1987-03-06 1988-09-08 キヤノン株式会社 眼内レンズ用組成物
JP2604831B2 (ja) * 1988-10-19 1997-04-30 株式会社メニコン バルーン型眼内レンズ用注入材料
JPH05310837A (ja) * 1992-05-14 1993-11-22 Japan Synthetic Rubber Co Ltd 酸素透過性高分子材料の製造方法
US5278258A (en) * 1992-05-18 1994-01-11 Allergan, Inc. Cross-linked silicone polymers, fast curing silicone precursor compositions, and injectable intraocular lenses
US5391590A (en) * 1993-01-12 1995-02-21 Allergan, Inc. Injectable intraocular lens compositions and precursors thereof
JPH08245734A (ja) * 1995-03-10 1996-09-24 Asahi Chem Ind Co Ltd 3次元架橋性ポリマーの製造方法及びこれを用いた眼科医療用ソフト材料
US6030416A (en) * 1998-02-13 2000-02-29 Pharmacia & Upjohn Ab Medical implants of stretch-crystallizable elastomers and methods of implantation
SE9803481D0 (sv) * 1998-10-13 1998-10-13 Pharmacia & Upjohn Ab Photocurable siloxane polymers
GB9822244D0 (en) * 1998-10-13 1998-12-09 Pharmacia & Upjohn Bv Intraocular lens forming material and lenses formed therefrom
KR100871500B1 (ko) * 1998-10-13 2008-12-05 에이엠오 그로닌겐 비.브이. 삽입형 인공수정체

Also Published As

Publication number Publication date
CA2403516C (en) 2010-10-26
KR20020093036A (ko) 2002-12-12
CA2403516A1 (en) 2001-10-18
AU2001263848B2 (en) 2006-05-11
EP1272233A1 (en) 2003-01-08
CN1422166A (zh) 2003-06-04
EP1272233B1 (en) 2005-08-31
DE60113085D1 (de) 2005-10-06
CZ20023354A3 (cs) 2003-03-12
CN1292805C (zh) 2007-01-03
AU6384801A (en) 2001-10-23
SE0001352D0 (sv) 2000-04-12
IL152242A0 (en) 2003-05-29
DE60113085T2 (de) 2006-06-29
HUP0300635A2 (en) 2003-09-29
JP4979173B2 (ja) 2012-07-18
JP2003530157A (ja) 2003-10-14
IL152242A (en) 2008-08-07
ATE303168T1 (de) 2005-09-15
WO2001076651A1 (en) 2001-10-18

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed