PE20010713A1 - Composicion farmaceutica acuosa que contiene ciclesonida - Google Patents
Composicion farmaceutica acuosa que contiene ciclesonidaInfo
- Publication number
- PE20010713A1 PE20010713A1 PE2000001119A PE0011192000A PE20010713A1 PE 20010713 A1 PE20010713 A1 PE 20010713A1 PE 2000001119 A PE2000001119 A PE 2000001119A PE 0011192000 A PE0011192000 A PE 0011192000A PE 20010713 A1 PE20010713 A1 PE 20010713A1
- Authority
- PE
- Peru
- Prior art keywords
- cyclesonide
- substance
- pharmaceutical composition
- composition containing
- aqueous pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000126 substance Substances 0.000 abstract 4
- 239000001814 pectin Substances 0.000 abstract 2
- 235000010987 pectin Nutrition 0.000 abstract 2
- 229920001277 pectin Polymers 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- AEMRFAOFKBGASW-UHFFFAOYSA-M Glycolate Chemical compound OCC([O-])=O AEMRFAOFKBGASW-UHFFFAOYSA-M 0.000 abstract 1
- 229920002907 Guar gum Polymers 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000000665 guar gum Substances 0.000 abstract 1
- 229960002154 guar gum Drugs 0.000 abstract 1
- 235000010417 guar gum Nutrition 0.000 abstract 1
- 229920000591 gum Polymers 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA ACUOSA QUE CONTIENE CICLESONIDA E HIDROXIPROPILMETILCELULOSA DE 0,01% p/p A 30% p/p; LA CICLESONIDA ESTA DISPERSA EN UN MEDIO ACUOSO EN FORMA DE PARTICULAS SOLIDAS, ADICIONALMENTE CONTIENE UNA SUSTANCIA INSOLUBLE EN AGUA Y/O UNA SUSTANCIA DE BAJA SOLUBILIDAD EN AGUA TAL COMO UNA CELULOSA CRISTALINA, UNA SUSTANCIA POLIMERICA SOLUBLE EN AGUA TAL COMO POLIETILENGLICOL, PROPILENGLICOL, ALGINATO, PECTINA, METOXIL PECTINA BAJA, GOMA GUAR, GOMA ARABIGA, CARRAGENINA, METILCELULOSA, CARBOXIMETILCELULOSA, GOMA XANTANO E HIDROXIPROPILCELULOSA. LA COMPOSICION PUEDE SER UTIL PARA EVITAR VARIACIONES EN LAS CONCENTRACIONES DE CICLESONIDA DURANTE LA PRODUCCION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29818699 | 1999-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010713A1 true PE20010713A1 (es) | 2001-07-13 |
Family
ID=17856339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000001119A PE20010713A1 (es) | 1999-10-20 | 2000-10-19 | Composicion farmaceutica acuosa que contiene ciclesonida |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US8383611B1 (es) |
| EP (1) | EP1227817B1 (es) |
| JP (1) | JP4856338B2 (es) |
| KR (1) | KR100705372B1 (es) |
| CN (1) | CN1198623C (es) |
| AR (1) | AR026073A1 (es) |
| AT (1) | ATE270107T1 (es) |
| AU (1) | AU776587B2 (es) |
| BG (1) | BG65799B1 (es) |
| BR (1) | BRPI0014880B8 (es) |
| CA (1) | CA2388325C (es) |
| CO (1) | CO5251406A1 (es) |
| CZ (1) | CZ297780B6 (es) |
| DE (1) | DE60011924T2 (es) |
| DK (1) | DK1227817T3 (es) |
| EA (1) | EA005201B1 (es) |
| ES (1) | ES2223595T3 (es) |
| HR (1) | HRP20020345B1 (es) |
| HU (1) | HU228894B1 (es) |
| IL (2) | IL148725A0 (es) |
| ME (1) | ME00568B (es) |
| MX (1) | MXPA02003975A (es) |
| MY (1) | MY121175A (es) |
| NO (1) | NO327379B1 (es) |
| NZ (1) | NZ518299A (es) |
| PE (1) | PE20010713A1 (es) |
| PL (1) | PL197537B1 (es) |
| PT (1) | PT1227817E (es) |
| RS (1) | RS50345B (es) |
| SI (1) | SI1227817T1 (es) |
| SK (1) | SK286194B6 (es) |
| TR (1) | TR200200831T2 (es) |
| TW (1) | TWI269655B (es) |
| WO (1) | WO2001028563A1 (es) |
| ZA (1) | ZA200203078B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR026073A1 (es) * | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
| EP1519734A4 (en) | 2002-07-02 | 2011-02-23 | Nycomed Gmbh | CICLESONIC STERILE AQUEOUS SUSPENSION |
| JP4746318B2 (ja) | 2002-08-30 | 2011-08-10 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | シクレソニドと抗ヒスタミン剤との組合せ物を含有するアレルギー性鼻炎の治療用医薬組成物 |
| US7879833B2 (en) | 2002-12-12 | 2011-02-01 | Nycomed Gmbh | Combination medicament |
| MY143936A (en) | 2003-03-27 | 2011-07-29 | Nycomed Gmbh | Process for preparing crystalline ciclesonide with defined particle size |
| DK1670482T4 (da) | 2003-09-16 | 2022-08-22 | Covis Pharma B V | Anvendelse af ciclesonid til behandlingen af respiratoriske sygdomme |
| PE20050941A1 (es) * | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
| CA2588433A1 (en) * | 2004-11-17 | 2006-05-26 | Michael R. Robinson | Steroid formulation and methods of treatment using same |
| JP5661985B2 (ja) * | 2006-12-27 | 2015-01-28 | 帝人ファーマ株式会社 | 無菌性水性懸濁製剤 |
| WO2009114521A1 (en) | 2008-03-11 | 2009-09-17 | Alcon Research, Ltd. | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
| CA2844944A1 (en) | 2011-08-18 | 2013-02-21 | Takeda Gmbh | Pharmaceutical aerosol product for administration by oral or nasal inhalation |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271143A (en) | 1978-01-25 | 1981-06-02 | Alcon Laboratories, Inc. | Sustained release ophthalmic drug dosage |
| CH657779A5 (de) | 1982-10-05 | 1986-09-30 | Sandoz Ag | Galenische zusammensetzungen enthaltend calcitonin. |
| AU572815B2 (en) | 1982-12-29 | 1988-05-19 | Armour Pharmaceutical Company | Pharmaceutical calcitonin compositions for intranasal application |
| JPS59163313A (ja) | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| JPH0830004B2 (ja) | 1983-11-14 | 1996-03-27 | コロンビア ラボラトリーズ インコーポレイテッド | 生物接着性組成物およびそれにより治療する方法 |
| GB8515132D0 (en) | 1985-06-14 | 1985-07-17 | British Nuclear Fuels Plc | Measuring photosynthetic activities of plants |
| US5179079A (en) | 1986-12-16 | 1993-01-12 | Novo Nordisk A/S | Nasal formulation and intranasal administration therewith |
| MY102411A (en) | 1986-12-23 | 1992-06-17 | Ciba Geigy Ag | Nasal solutions |
| JPH0744940B2 (ja) | 1986-12-24 | 1995-05-17 | ライオン株式会社 | 口腔貼付用基材 |
| US4802967A (en) | 1987-04-08 | 1989-02-07 | Andus Corporation | Surface treatment of polymers |
| JPS63303931A (ja) | 1987-06-05 | 1988-12-12 | Sumitomo Pharmaceut Co Ltd | 経鼻投与用成長ホルモン放出活性物質製剤 |
| US4788220A (en) | 1987-07-08 | 1988-11-29 | American Home Products Corporation (Del.) | Pediatric ibuprofen compositions |
| US5192535A (en) | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| US5188826A (en) | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| US5776493A (en) | 1989-07-14 | 1998-07-07 | Alza Corporation | Oral osmotic device for delivery of nystatin with hydrogel driving member |
| DK0431719T3 (da) | 1989-10-31 | 1995-02-27 | Columbia Lab Inc | Vaginalt vævsbefugtende præparat |
| US5147654A (en) | 1990-07-23 | 1992-09-15 | Alza Corporation | Oral osmotic device for delivering nicotine |
| JPH078806B2 (ja) | 1990-08-16 | 1995-02-01 | 旭化成工業株式会社 | カルシトニン類含有経鼻投与用乳剤 |
| GB9102579D0 (en) | 1991-01-24 | 1991-03-27 | Glaxo Group Ltd | Compositions |
| GB9103824D0 (en) | 1991-02-23 | 1991-04-10 | Fisons Ag | Formulation |
| DE69233116T2 (de) | 1991-04-03 | 2004-08-26 | Keimowitz, Rudolph M.D., Wayzata | Unterdrückung der thromboxanspiegel durch perkutane verabreichung von aspirin |
| IT1250691B (it) * | 1991-07-22 | 1995-04-21 | Giancarlo Santus | Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac. |
| US5200195A (en) | 1991-12-06 | 1993-04-06 | Alza Corporation | Process for improving dosage form delivery kinetics |
| JP2860729B2 (ja) | 1992-03-10 | 1999-02-24 | エスエス製薬株式会社 | プラノプロフェン懸濁シロップ剤 |
| CA2101126A1 (en) | 1992-08-03 | 1994-02-04 | Yasushi Morita | Preparation for local treatment |
| JP3047948B2 (ja) | 1992-12-07 | 2000-06-05 | 株式会社ツムラ | ペプチド類経鼻投与用組成物 |
| US5340572A (en) | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
| US5409703A (en) | 1993-06-24 | 1995-04-25 | Carrington Laboratories, Inc. | Dried hydrogel from hydrophilic-hygroscopic polymer |
| JP2787131B2 (ja) | 1993-07-30 | 1998-08-13 | 千寿製薬株式会社 | 水性懸濁液剤 |
| US5540930A (en) | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
| JP3781792B2 (ja) | 1993-12-27 | 2006-05-31 | 千寿製薬株式会社 | ジフルプレドナート含有点眼用懸濁液剤 |
| JPH07188059A (ja) | 1993-12-28 | 1995-07-25 | Rohto Pharmaceut Co Ltd | 歯周病治療剤 |
| RU2102979C1 (ru) | 1994-07-18 | 1998-01-27 | Панкрушева Татьяна Александровна | Средство для лечения гнойно-воспалительных процессов кожи и слизистых оболочек различной этиологии |
| US5726181A (en) | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
| AU6392496A (en) | 1995-06-29 | 1997-01-30 | Mcneil-Ppc, Inc. | The combination of topical nasal antihistamines and topical nasal steroids |
| JP3098401B2 (ja) | 1995-07-12 | 2000-10-16 | 株式会社エルティーティー研究所 | 経鼻投与用製剤 |
| JP2791317B2 (ja) | 1995-12-26 | 1998-08-27 | 株式会社三和化学研究所 | 多層フィルム製剤 |
| ES2205177T5 (es) | 1996-02-27 | 2007-08-01 | Teijin Limited | Composicion en polvo para administracion nasal. |
| US5976573A (en) | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
| US5955097A (en) | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
| IT1286496B1 (it) | 1996-11-20 | 1998-07-15 | Leetrim Ltd Dublin | Composizione farmaceutica orale ad attivita' antipiretica,analgesica ed antiinfiammatoria |
| SE9604486D0 (sv) | 1996-12-05 | 1996-12-05 | Astra Ab | Novel formulation |
| FR2756739B1 (fr) | 1996-12-05 | 2000-04-28 | Astra Ab | Nouvelle formulation de budesonide |
| TW503113B (en) | 1997-01-16 | 2002-09-21 | Senju Pharma Co | Aqueous suspension for nasal administration |
| US6120752A (en) * | 1997-05-21 | 2000-09-19 | 3M Innovative Properties Company | Medicinal aerosol products containing formulations of ciclesonide and related steroids |
| JPH1121229A (ja) | 1997-06-30 | 1999-01-26 | Kyoto Yakuhin Kogyo Kk | 抗真菌性外用製剤およびその製造方法 |
| JPH11130658A (ja) | 1997-10-30 | 1999-05-18 | Teijin Ltd | 水性懸濁医薬品組成物 |
| JP3386348B2 (ja) | 1997-10-30 | 2003-03-17 | 帝人株式会社 | 鼻腔内投与用水性懸濁製剤 |
| JP3386349B2 (ja) | 1997-10-30 | 2003-03-17 | 帝人株式会社 | 水性懸濁医薬品組成物 |
| SE9704186D0 (sv) * | 1997-11-14 | 1997-11-14 | Astra Ab | New composition of matter |
| KR100683510B1 (ko) | 1998-01-22 | 2007-02-16 | 산텐 세이야꾸 가부시키가이샤 | 플루오로메톨론 현탁형 점안제 |
| SE514128C2 (sv) * | 1998-03-17 | 2001-01-08 | Pharmalink Ab | Användning av en glukokortikoid för framställning av ett läkemedel för behandling av glomerulonefrit |
| TWI243687B (en) | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
| US6124268A (en) * | 1999-02-17 | 2000-09-26 | Natreon Inc. | Natural antioxidant compositions, method for obtaining same and cosmetic, pharmaceutical and nutritional formulations thereof |
| RU11829U1 (ru) | 1999-05-05 | 1999-11-16 | Специальное конструкторское бюро транспортного машиностроения (ОАО Спецмаш) | Рабочая площадка для буровых установок |
| AR026072A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa |
| WO2001028517A1 (fr) | 1999-10-20 | 2001-04-26 | Teijin Limited | Compositions therapeutiques aqueuses |
| AR026073A1 (es) * | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
-
2000
- 2000-10-18 AR ARP000105474A patent/AR026073A1/es not_active Application Discontinuation
- 2000-10-19 MY MYPI20004916A patent/MY121175A/en unknown
- 2000-10-19 CO CO00079609A patent/CO5251406A1/es active IP Right Grant
- 2000-10-19 PE PE2000001119A patent/PE20010713A1/es not_active IP Right Cessation
- 2000-10-19 TW TW089121991A patent/TWI269655B/zh not_active IP Right Cessation
- 2000-10-20 DE DE60011924T patent/DE60011924T2/de not_active Expired - Lifetime
- 2000-10-20 SK SK693-2002A patent/SK286194B6/sk not_active IP Right Cessation
- 2000-10-20 ME MEP-2008-857A patent/ME00568B/me unknown
- 2000-10-20 CZ CZ20021284A patent/CZ297780B6/cs not_active IP Right Cessation
- 2000-10-20 EP EP00969967A patent/EP1227817B1/en not_active Expired - Lifetime
- 2000-10-20 AT AT00969967T patent/ATE270107T1/de active
- 2000-10-20 JP JP2001531393A patent/JP4856338B2/ja not_active Expired - Lifetime
- 2000-10-20 KR KR1020027004994A patent/KR100705372B1/ko not_active Expired - Lifetime
- 2000-10-20 CN CNB00814253XA patent/CN1198623C/zh not_active Expired - Lifetime
- 2000-10-20 AU AU79532/00A patent/AU776587B2/en not_active Expired
- 2000-10-20 SI SI200030483T patent/SI1227817T1/xx unknown
- 2000-10-20 EA EA200200383A patent/EA005201B1/ru not_active IP Right Cessation
- 2000-10-20 DK DK00969967T patent/DK1227817T3/da active
- 2000-10-20 ES ES00969967T patent/ES2223595T3/es not_active Expired - Lifetime
- 2000-10-20 HR HR20020345A patent/HRP20020345B1/xx not_active IP Right Cessation
- 2000-10-20 IL IL14872500A patent/IL148725A0/xx active IP Right Grant
- 2000-10-20 PL PL356190A patent/PL197537B1/pl unknown
- 2000-10-20 TR TR2002/00831T patent/TR200200831T2/xx unknown
- 2000-10-20 CA CA002388325A patent/CA2388325C/en not_active Expired - Fee Related
- 2000-10-20 NZ NZ518299A patent/NZ518299A/en not_active IP Right Cessation
- 2000-10-20 HU HU0203756A patent/HU228894B1/hu unknown
- 2000-10-20 RS YUP-281/02A patent/RS50345B/sr unknown
- 2000-10-20 PT PT00969967T patent/PT1227817E/pt unknown
- 2000-10-20 US US10/110,632 patent/US8383611B1/en not_active Expired - Fee Related
- 2000-10-20 WO PCT/JP2000/007351 patent/WO2001028563A1/en not_active Ceased
- 2000-10-20 BR BRPI0014880A patent/BRPI0014880B8/pt not_active IP Right Cessation
- 2000-10-20 MX MXPA02003975A patent/MXPA02003975A/es active IP Right Grant
-
2002
- 2002-03-14 BG BG106517A patent/BG65799B1/bg unknown
- 2002-03-17 IL IL148725A patent/IL148725A/en unknown
- 2002-04-18 ZA ZA200203078A patent/ZA200203078B/xx unknown
- 2002-04-19 NO NO20021866A patent/NO327379B1/no not_active IP Right Cessation
-
2012
- 2012-11-29 US US13/688,659 patent/US20130095146A1/en not_active Abandoned
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