KR900008317B1 - N-heterocyclic-n-(4-piperidyl)amides and their compositions - Google Patents
N-heterocyclic-n-(4-piperidyl)amides and their compositionsInfo
- Publication number
- KR900008317B1 KR900008317B1 KR8800946A KR880000946A KR900008317B1 KR 900008317 B1 KR900008317 B1 KR 900008317B1 KR 8800946 A KR8800946 A KR 8800946A KR 880000946 A KR880000946 A KR 880000946A KR 900008317 B1 KR900008317 B1 KR 900008317B1
- Authority
- KR
- South Korea
- Prior art keywords
- piperidyl
- lower alkyl
- amides
- heterocyclic
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/009857 | 1987-02-02 | ||
| US07/009,857 US4791112A (en) | 1987-02-02 | 1987-02-02 | N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR880009928A KR880009928A (ko) | 1988-10-05 |
| KR900008317B1 true KR900008317B1 (en) | 1990-11-12 |
Family
ID=21740121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR8800946A Expired KR900008317B1 (en) | 1987-02-02 | 1988-02-01 | N-heterocyclic-n-(4-piperidyl)amides and their compositions |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4791112A (ko) |
| EP (1) | EP0277794B1 (ko) |
| JP (1) | JPH0662565B2 (ko) |
| KR (1) | KR900008317B1 (ko) |
| CN (1) | CN88100563A (ko) |
| AU (1) | AU598905B2 (ko) |
| DE (1) | DE3889133T2 (ko) |
| DK (1) | DK49388A (ko) |
| ES (1) | ES2063030T3 (ko) |
| FI (1) | FI90980C (ko) |
| MX (1) | MX9203099A (ko) |
| NO (1) | NO169070C (ko) |
| NZ (1) | NZ223314A (ko) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
| ES2053480T3 (es) * | 1986-07-31 | 1994-08-01 | Otsuka Pharma Co Ltd | Un procedimiento para preparar un derivado de carboestirilo. |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| USRE34201E (en) * | 1989-04-20 | 1993-03-23 | Anaquest, Inc. | N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds |
| JPH0667923B2 (ja) * | 1989-05-11 | 1994-08-31 | 東洋紡績株式会社 | 新規なベンゾチアゾール誘導体 |
| FR2662162B1 (fr) * | 1990-05-18 | 1995-01-20 | Adir | Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2665898B1 (fr) * | 1990-08-20 | 1994-03-11 | Sanofi | Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5345554A (en) * | 1992-04-17 | 1994-09-06 | Intel Corporation | Visual frame buffer architecture |
| BR9909666A (pt) | 1998-03-26 | 2001-09-11 | Japan Tobacco Inc | Derivados de amida e antagonistas de nociceptina |
| US6927214B1 (en) | 1999-01-15 | 2005-08-09 | Novo Nordisk A/S | Non-peptide GLP-1 agonists |
| US7361666B2 (en) | 1999-05-25 | 2008-04-22 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
| US6645980B1 (en) | 2000-05-25 | 2003-11-11 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
| US6677332B1 (en) | 1999-05-25 | 2004-01-13 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
| US6635661B2 (en) | 2000-05-25 | 2003-10-21 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
| US6476050B2 (en) | 2000-03-14 | 2002-11-05 | Sepracor, Inc. | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
| DK1443046T3 (da) * | 2001-10-09 | 2009-04-14 | Kyorin Seiyaku Kk | Nye 4-(2-furoyl)-amino-piperidiner, mellemprodukter til deres syntese, fremgangsmåde til deres fremstilling og deres medicinske anvendelse |
| GB0205176D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| MXPA05012007A (es) * | 2003-05-08 | 2006-05-31 | Kyorin Seiyaku Kk | Compuesto de 4- (2-furoil) aminopiperidina util como agente terapeutico para el prurito. |
| TW200526626A (en) * | 2003-09-13 | 2005-08-16 | Astrazeneca Ab | Chemical compounds |
| EP1853586B1 (en) * | 2005-02-18 | 2013-07-24 | AstraZeneca AB | Antibacterial piperidine derivatives |
| US20080161306A1 (en) * | 2005-02-18 | 2008-07-03 | Brian Sherer | Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors |
| CN101171247A (zh) * | 2005-03-04 | 2008-04-30 | 阿斯利康(瑞典)有限公司 | 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物 |
| JP2008531673A (ja) * | 2005-03-04 | 2008-08-14 | アストラゼネカ アクチボラグ | 抗菌活性をもつアゼチジン及びピロールの三環式誘導体 |
| TW200906412A (en) * | 2007-06-12 | 2009-02-16 | Astrazeneca Ab | Piperidine compounds and uses thereof |
| CN106642052A (zh) * | 2017-01-05 | 2017-05-10 | 郑州坤博科技有限公司 | 一种流化床锅炉 |
| CN108503579B (zh) * | 2018-03-28 | 2021-03-26 | 南京医科大学 | 芬太尼类似物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2341965C3 (de) * | 1973-08-20 | 1979-01-25 | C.H. Boehringer Sohn, 6507 Ingelheim | 4- [N- (o-PyridyD- N-acyl] -aminolphenäthylpiperidine, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Schmerzzuständen |
| ZA765684B (en) * | 1975-09-23 | 1978-04-26 | Janssen Pharmaceutica Nv | Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| US4584303A (en) * | 1984-04-09 | 1986-04-22 | The Boc Group, Inc. | N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds |
| US4589303A (en) * | 1984-08-24 | 1986-05-20 | Borg-Warner Corporation | Continuously variable transmission with synchronous shift |
| US4546105A (en) * | 1984-09-04 | 1985-10-08 | Hoechst-Roussel Pharmaceuticals Inc. | Pyrrolylaminopiperidines, compositions thereof and methods of use |
-
1987
- 1987-02-02 US US07/009,857 patent/US4791112A/en not_active Expired - Fee Related
-
1988
- 1988-01-27 NZ NZ223314A patent/NZ223314A/xx unknown
- 1988-02-01 AU AU11142/88A patent/AU598905B2/en not_active Ceased
- 1988-02-01 DE DE3889133T patent/DE3889133T2/de not_active Expired - Fee Related
- 1988-02-01 ES ES88300829T patent/ES2063030T3/es not_active Expired - Lifetime
- 1988-02-01 DK DK049388A patent/DK49388A/da not_active Application Discontinuation
- 1988-02-01 FI FI880452A patent/FI90980C/fi not_active IP Right Cessation
- 1988-02-01 KR KR8800946A patent/KR900008317B1/ko not_active Expired
- 1988-02-01 EP EP88300829A patent/EP0277794B1/en not_active Expired - Lifetime
- 1988-02-02 CN CN198888100563A patent/CN88100563A/zh active Pending
- 1988-02-02 NO NO880443A patent/NO169070C/no unknown
- 1988-02-02 JP JP63022650A patent/JPH0662565B2/ja not_active Expired - Fee Related
-
1992
- 1992-06-22 MX MX9203099A patent/MX9203099A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ223314A (en) | 1989-09-27 |
| FI880452L (fi) | 1988-08-03 |
| EP0277794A3 (en) | 1989-10-25 |
| NO169070B (no) | 1992-01-27 |
| FI880452A0 (fi) | 1988-02-01 |
| DE3889133D1 (de) | 1994-05-26 |
| KR880009928A (ko) | 1988-10-05 |
| DE3889133T2 (de) | 1994-08-25 |
| NO880443D0 (no) | 1988-02-02 |
| EP0277794A2 (en) | 1988-08-10 |
| NO169070C (no) | 1992-05-06 |
| NO880443L (no) | 1988-08-03 |
| JPH0662565B2 (ja) | 1994-08-17 |
| US4791112A (en) | 1988-12-13 |
| FI90980B (fi) | 1994-01-14 |
| MX9203099A (es) | 1992-07-31 |
| JPS63264460A (ja) | 1988-11-01 |
| DK49388D0 (da) | 1988-02-01 |
| CN88100563A (zh) | 1988-08-17 |
| EP0277794B1 (en) | 1994-04-20 |
| ES2063030T3 (es) | 1995-01-01 |
| FI90980C (fi) | 1994-04-25 |
| AU598905B2 (en) | 1990-07-05 |
| DK49388A (da) | 1988-08-03 |
| AU1114288A (en) | 1988-08-04 |
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St.27 status event code: A-3-3-R10-R17-oth-X000 |
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| A201 | Request for examination | ||
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| PG1501 | Laying open of application |
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| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
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St.27 status event code: U-3-3-T10-T11-oth-X000 |
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St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
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| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
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| E701 | Decision to grant or registration of patent right | ||
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