KR890701758A - 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신 - Google Patents

재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신

Info

Publication number: KR890701758A
Authority: KR; South Korea
Prior art keywords: recombinant dna; analogs; vaccines; same; subunits derived
Prior art date: 1987-09-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

KR1019890700803A

Other languages

English (en)

Other versions

KR0168039B1 (ko

Inventor

닐 버네트 3세 월터

Original Assignee

암젠 인코포레이티드

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-04

Filing date

1989-05-04

Publication date

1989-12-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26788722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR890701758(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-08-26 Application filed by 암젠 인코포레이티드 filed Critical 암젠 인코포레이티드

1989-12-21 Publication of KR890701758A publication Critical patent/KR890701758A/ko

1999-01-15 Application granted granted Critical

1999-01-15 Publication of KR0168039B1 publication Critical patent/KR0168039B1/ko

2008-08-26 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

OTLLEIBWKHEHGU-UHFFFAOYSA-N 2-[5-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-4-phosphonooxyhexanedioic acid Chemical compound C1=NC=2C(N)=NC=NC=2N1C(C(C1O)O)OC1COC1C(CO)OC(OC(C(O)C(OP(O)(O)=O)C(O)C(O)=O)C(O)=O)C(O)C1O OTLLEIBWKHEHGU-UHFFFAOYSA-N 0.000 title abstract 2
241000588807 Bordetella Species 0.000 title abstract 2
108020004511 Recombinant DNA Proteins 0.000 title abstract 2
231100000776 exotoxin Toxicity 0.000 title abstract 2
239000002095 exotoxin Substances 0.000 title abstract 2
229960005486 vaccine Drugs 0.000 title abstract 2
108010008038 Synthetic Vaccines Proteins 0.000 title 1
230000004071 biological effect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
230000002163 immunogen Effects 0.000 abstract 1
230000005847 immunogenicity Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
239000003053 toxin Substances 0.000 abstract 1
231100000765 toxin Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

KR1019890700803A 1987-09-04 1988-08-26 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신 Expired - Fee Related KR0168039B1 (ko)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US9430787A	1987-09-04	1987-09-04
US094,307		1987-09-04
US23248288A	1988-08-17	1988-08-17
US232,482		1988-08-17
PCT/US1988/002983 WO1989001976A1 (en)	1987-09-04	1988-08-26	Recombinant dna-derived bordetella toxin subunit analogs

Publications (2)

Publication Number	Publication Date
KR890701758A true KR890701758A (ko)	1989-12-21
KR0168039B1 KR0168039B1 (ko)	1999-01-15

Family

ID=26788722

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019890700803A Expired - Fee Related KR0168039B1 (ko)	1987-09-04	1988-08-26	재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신

Country Status (16)

Country	Link
US (1)	US5773600A (ko)
EP (2)	EP0306318B2 (ko)
JP (1)	JP2918895B2 (ko)
KR (1)	KR0168039B1 (ko)
CN (1)	CN1033866C (ko)
AT (1)	ATE125568T1 (ko)
CA (1)	CA1341560C (ko)
DE (1)	DE3854213T3 (ko)
DK (1)	DK175821B1 (ko)
ES (1)	ES2076160T5 (ko)
FI (1)	FI101632B (ko)
GR (1)	GR3017497T3 (ko)
IE (1)	IE69753B1 (ko)
IL (3)	IL87608A0 (ko)
NO (2)	NO301844B1 (ko)
WO (1)	WO1989001976A1 (ko)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6713072B1 (en) *	1987-11-02	2004-03-30	Chiron S.R.L.	Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
IT1223334B (it) *	1987-11-02	1990-09-19	Sclavo Spa	Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
US5925546A (en) *	1987-11-02	1999-07-20	Chiron S.P.A.	Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
GB8727489D0 (en) *	1987-11-24	1987-12-23	Connaught Lab	Detoxification of pertussis toxin
US5332583A (en) *	1987-11-24	1994-07-26	Connaught Laboratories Limited	Vaccine containing genetically-detoxified pertussis holotoxin
US5358868A (en) *	1987-11-24	1994-10-25	Connaught Laboratories Limited	Genetic detoxification of pertussis toxin
US7232671B2 (en) *	1989-02-15	2007-06-19	The United States Of America As Represented By The Secretary, Department Of Health And Human Services	Pertussis toxin gene: cloning and expression of protective antigen
CA2009991A1 (en) *	1989-02-15	1990-08-15	Witold Cieplak	Pertussis toxin gene: cloning and expression of protective antigen
ES2078258T3 (es) *	1989-04-28	1995-12-16	Sclavo Spa	Mutantes de toxina pertussica, cepas de bordetella capaces de producir tales mutantes y su uso en el desarrollo de vacunas antipertussicas.
US5786189A (en) *	1989-11-29	1998-07-28	Smithkline Beecham Biologicals (S.A.)	Vaccine
GB9326174D0 (en) *	1993-12-22	1994-02-23	Biocine Sclavo	Mucosal adjuvant
US20030072774A1 (en) *	1994-06-10	2003-04-17	Diane M. Gajewczyk	Proteinaceous adjuvants
CA2220063C (en) *	1995-05-04	2003-08-26	Connaught Laboratories Limited	Acellular pertussis vaccines and methods of preparation thereof
EP0912726A4 (en) *	1996-05-10	2001-07-18	Phylomed Corp	METHODS FOR OXIDIZING BISULFIDE LINKS WITH OZONE
FR2754543B1 (fr)	1996-10-11	1998-12-31	Pasteur Institut	Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US6818222B1 (en)	1997-03-21	2004-11-16	Chiron Corporation	Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US9453251B2 (en)	2002-10-08	2016-09-27	Pfenex Inc.	Expression of mammalian proteins in Pseudomonas fluorescens
GB0313916D0 (en)	2003-06-16	2003-07-23	Glaxosmithkline Biolog Sa	Vaccine composition
US8603824B2 (en)	2004-07-26	2013-12-10	Pfenex, Inc.	Process for improved protein expression by strain engineering
DK1828378T3 (da) *	2004-12-17	2014-09-01	Staat Der Nederlanden Vert Door De Minister Van Vws Ministerie Van Volksgezondheit Welzijn En Sport	Deacylering af LPS i gram-negative bakterier
US9580719B2 (en)	2007-04-27	2017-02-28	Pfenex, Inc.	Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
MX2009011523A (es)	2007-04-27	2009-11-09	Dow Global Technologies Inc	Metodo para clasificar rapidamente huespedes microbianos para identificar ciertas cepas con rendimiento y/o calidad mejorados en la expresion de proteinas heterologas.
ITMI20090946A1 (it)	2009-05-28	2010-11-29	Novartis Ag	Espressione di proteine ricombinanti
BR112012024898A2 (pt)	2010-03-30	2015-10-06	Pfenex Inc	expressão de nível elevado de proteínas recombinantes de toxinas
US9169304B2 (en)	2012-05-01	2015-10-27	Pfenex Inc.	Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US20140037680A1 (en)	2012-08-06	2014-02-06	Glaxosmithkline Biologicals, S.A.	Novel method
CA2879939A1 (en)	2012-08-06	2014-02-13	Glaxosmithkline Biologicals S.A.	Novel method
DK2863943T3 (en)	2013-03-08	2016-11-07	Janssen Vaccines & Prevention Bv	acellular pertussis vaccines
JP6564367B2 (ja)	2013-08-05	2019-08-21	グラクソスミスクラインバイオロジカルズソシエテアノニム	併用免疫原性組成物
CN109172818B (zh) *	2018-08-02	2021-10-22	浙江康佰裕生物科技有限公司	一种蛋白牛痘疫苗及其效力检测方法
WO2020081548A1 (en) *	2018-10-15	2020-04-23	Arizona Board Of Regents On Behalf Of The University Of Arizona	Vaccine polypeptide compositions and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4704362A (en) *	1977-11-08	1987-11-03	Genentech, Inc.	Recombinant cloning vehicle microbial polypeptide expression
FR2590483B1 (fr) *	1985-11-22	1988-12-09	Pasteur Institut	Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
CA1340373C (en) *	1986-01-28	1999-02-02	Rino Rappuoli	Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin
ATE80179T1 (de) *	1986-12-23	1992-09-15	Univ Leland Stanford Junior	Modifiziertes pertussistoxin.
IT1223334B (it) *	1987-11-02	1990-09-19	Sclavo Spa	Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
GB8727489D0 (en) *	1987-11-24	1987-12-23	Connaught Lab	Detoxification of pertussis toxin
IT1223529B (it) *	1987-12-18	1990-09-19	Sclavo Spa	Epitopo immunodominante protettivo contenuto nella subunita' s1 della tossina della pertosse

1988
- 1988-08-26 KR KR1019890700803A patent/KR0168039B1/ko not_active Expired - Fee Related
- 1988-08-26 WO PCT/US1988/002983 patent/WO1989001976A1/en not_active Ceased
- 1988-08-26 JP JP63507460A patent/JP2918895B2/ja not_active Expired - Lifetime
- 1988-08-30 IL IL87608A patent/IL87608A0/xx not_active IP Right Cessation
- 1988-08-30 IL IL10312188A patent/IL103121A/en not_active IP Right Cessation
- 1988-09-01 ES ES88308124T patent/ES2076160T5/es not_active Expired - Lifetime
- 1988-09-01 EP EP88308124A patent/EP0306318B2/en not_active Expired - Lifetime
- 1988-09-01 EP EP94109317A patent/EP0629696A1/en not_active Withdrawn
- 1988-09-01 AT AT88308124T patent/ATE125568T1/de not_active IP Right Cessation
- 1988-09-01 DE DE3854213T patent/DE3854213T3/de not_active Expired - Lifetime
- 1988-09-02 IE IE266888A patent/IE69753B1/en not_active IP Right Cessation
- 1988-09-02 CA CA 576469 patent/CA1341560C/en not_active Expired - Fee Related
- 1988-09-05 CN CN88107056A patent/CN1033866C/zh not_active Expired - Lifetime
1989
- 1989-05-03 FI FI892131A patent/FI101632B/fi not_active IP Right Cessation
- 1989-05-03 DK DK198902162A patent/DK175821B1/da active
- 1989-05-03 NO NO891842A patent/NO301844B1/no not_active IP Right Cessation
1992
- 1992-09-09 IL IL103121A patent/IL103121A0/xx unknown
1995
- 1995-06-06 US US08/468,679 patent/US5773600A/en not_active Expired - Lifetime
- 1995-09-21 GR GR950402614T patent/GR3017497T3/el unknown
1997
- 1997-06-09 NO NO19972642A patent/NO325016B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR0168039B1 (ko)	1999-01-15
NO972642L (no)	1997-07-28
NO891842D0 (no)	1989-05-03
AU2386488A (en)	1989-03-31
IL87608A0 (en)	1989-01-31
EP0306318A1 (en)	1989-03-08
NO972642D0 (no)	1997-06-09
DK216289A (da)	1989-06-30
NO301844B1 (no)	1997-12-15
DE3854213T2 (de)	1995-12-07
ATE125568T1 (de)	1995-08-15
DK216289D0 (da)	1989-05-03
EP0306318B2 (en)	2004-04-28
IE882668L (en)	1989-03-04
WO1989001976A1 (en)	1989-03-09
FI101632B1 (fi)	1998-07-31
ES2076160T3 (es)	1995-11-01
CN1033866C (zh)	1997-01-22
EP0629696A1 (en)	1994-12-21
EP0306318B1 (en)	1995-07-26
JP2918895B2 (ja)	1999-07-12
CA1341560C (en)	2007-10-30
FI101632B (fi)	1998-07-31
DE3854213D1 (de)	1995-08-31
NO891842L (no)	1989-06-21
JPH04501051A (ja)	1992-02-27
NO325016B1 (no)	2008-01-14
AU623867B2 (en)	1992-05-28
FI892131A0 (fi)	1989-05-03
ES2076160T5 (es)	2004-12-01
US5773600A (en)	1998-06-30
GR3017497T3 (en)	1995-12-31
IE69753B1 (en)	1996-10-02
IL103121A0 (en)	1993-02-21
CN1033072A (zh)	1989-05-24
DE3854213T3 (de)	2004-10-21
DK175821B1 (da)	2005-03-14
FI892131L (fi)	1989-05-03
IL103121A (en)	1995-08-31

Publication	Publication Date	Title
KR890701758A (ko)	1989-12-21	재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신
ES2156110T3 (es)	2001-06-16	Analogos de sub-unidades de toxina del colera derivados de adn recombinante.
MX9203458A (es)	1992-09-01	Segmentos inmunogenicos que contienen glicoproteinas quimericas de las glicoproteinas de virus sincitial respiratorio humano.
PT625053E (pt)	2002-09-30	Vacina a base de urease contra a infeccao por helicobacter
ATE181572T1 (de)	1999-07-15	Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe
LU91595I2 (fr)	2009-10-12	Combinaison d'anatoxine diphtérique, d'anatoxine tétanique, d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine et de polyoside capsulaire d'haemophilus influenzae type b (InfanrixHib)
DE69031351D1 (de)	1997-10-02	Zubereitungen und behandlungen von pneumonia in tieren
DE69228944D1 (de)	1999-05-20	Bovines herpesvirus typ 1rekombinantenpolypeptide und vakzine
DK0775746T3 (da)	2006-04-03	Vaccine mod fjerkræcoccidiose
ATE182270T1 (de)	1999-08-15	Mukosale verabreichung von pneumokokken-antigenen
DK0563254T3 (da)	1996-02-12	Anvendelse af IL-4 til forstærkning af immunrespons på immunogener i vacciner
EP0636030A4 (en)	1996-02-07	VACCINE AGAINST THE -I BACTERIAL OXIDE (PASTEURELLIA HAEMOLYTICA).
Saint-Gérand	1988	Towards a second generation of inactivated vaccines: Use of herpesvirus (feline rhinotracheitis virus) subunits for the prevention of cat flu
DK230890A (da)	1990-09-24	Dna-fragment, der koder for et pasteurella multocida-toxin eller for en subsekvens eller analog deraf, ekspressionsvektor, der omfatter dna-fragmentet, mikroorganisme, der udtrykker dette, fremgangsmaade til fremstilling af et pasteurella-multocida-toxin, diagnostisk middel samt anvendelse heraf, vaccine indeholdende et pasteurella-multocida-toxinderivat, anvendelse af pasteurella multocida-t m.m.

Legal Events

Date	Code	Title	Description
1989-05-04	PA0109	Patent application	Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19890504
1989-12-21	PG1501	Laying open of application
1993-08-19	A201	Request for examination
1993-08-19	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 19930819 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19890504 Comment text: Patent Application
1997-02-20	E902	Notification of reason for refusal
1997-02-20	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 19970220 Patent event code: PE09021S01D
1997-11-20	E902	Notification of reason for refusal
1997-11-20	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 19971120 Patent event code: PE09021S01D
1998-07-06	E701	Decision to grant or registration of patent right
1998-07-06	PE0701	Decision of registration	Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19980706
1998-10-01	GRNT	Written decision to grant
1998-10-01	PR0701	Registration of establishment	Comment text: Registration of Establishment Patent event date: 19981001 Patent event code: PR07011E01D
1998-10-01	PR1002	Payment of registration fee	Payment date: 19981001 End annual number: 3 Start annual number: 1
1999-01-15	PG1601	Publication of registration
2001-09-28	PR1001	Payment of annual fee	Payment date: 20010928 Start annual number: 4 End annual number: 4
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2009-10-02	LAPS	Lapse due to unpaid annual fee
2009-10-02	PC1903	Unpaid annual fee	Termination category: Default of registration fee Termination date: 20100910