IS2991B - Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs - Google Patents

Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs

Info

Publication number: IS2991B
Authority: IS; Iceland
Prior art keywords: receptor antagonist; nanoparticle composition; tachykinin receptor; pharmaceutical nanoparticle; pharmaceutical
Prior art date: 2001-12-10

Application number

IS7276A

Other languages

English (en)

Other versions

IS7276A (is

Inventor

H. Bosch William

Liversidge Elaine

D. Shelukar Suhas

C. Thompson Karen

Original Assignee

Merck Sharp & Dohme Corp., (A New Jersey Corporation)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-10

Filing date

2004-05-21

Publication date

2017-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23331619&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2991(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-05-21 Application filed by Merck Sharp & Dohme Corp., (A New Jersey Corporation) filed Critical Merck Sharp & Dohme Corp., (A New Jersey Corporation)

2004-05-21 Publication of IS7276A publication Critical patent/IS7276A/is

2017-12-15 Publication of IS2991B publication Critical patent/IS2991B/is

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Otolaryngology (AREA)
Rheumatology (AREA)
Physics & Mathematics (AREA)
Nanotechnology (AREA)
Optics & Photonics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

IS7276A 2001-12-10 2004-05-21 Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs IS2991B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US34004001P	2001-12-10	2001-12-10
PCT/US2002/041655 WO2003049718A1 (en)	2001-12-10	2002-12-09	Pharmaceutical nanoparticulate composition of a tachykinin receptor antagonist

Publications (2)

Publication Number	Publication Date
IS7276A IS7276A (is)	2004-05-21
IS2991B true IS2991B (is)	2017-12-15

Family

ID=23331619

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7276A IS2991B (is)	2001-12-10	2004-05-21	Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs

Country Status (38)

Country	Link
US (1)	US8258132B2 (is)
EP (1)	EP1455756B2 (is)
JP (1)	JP4532114B2 (is)
KR (1)	KR20040063991A (is)
CN (1)	CN100352443C (is)
AR (1)	AR037713A1 (is)
AT (1)	ATE400254T1 (is)
AU (1)	AU2002360824B8 (is)
BR (1)	BRPI0214786B8 (is)
CA (1)	CA2469315C (is)
CO (1)	CO5590887A2 (is)
CY (1)	CY1108354T1 (is)
DE (1)	DE60227556D1 (is)
DK (1)	DK1455756T4 (is)
DO (1)	DOP2002000542A (is)
EA (1)	EA007332B1 (is)
EC (1)	ECSP045144A (is)
ES (1)	ES2307820T5 (is)
GE (1)	GEP20063875B (is)
HR (1)	HRP20040532B1 (is)
HU (1)	HU230736B1 (is)
IL (3)	IL162296A0 (is)
IS (1)	IS2991B (is)
JO (1)	JO3060B1 (is)
ME (1)	ME00450B (is)
MX (1)	MXPA04005563A (is)
MY (1)	MY155911A (is)
NO (1)	NO336943B1 (is)
NZ (1)	NZ534009A (is)
PE (1)	PE20030641A1 (is)
PL (1)	PL211243B6 (is)
PT (1)	PT1455756E (is)
RS (1)	RS52280B (is)
SI (1)	SI1455756T2 (is)
TW (1)	TWI249403B (is)
UA (1)	UA76810C2 (is)
WO (1)	WO2003049718A1 (is)
ZA (1)	ZA200404012B (is)

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2002
- 2002-09-12 UA UA20040705610A patent/UA76810C2/uk unknown
- 2002-12-03 JO JOP/2002/0126A patent/JO3060B1/ar active
- 2002-12-04 MY MYPI20024570A patent/MY155911A/en unknown
- 2002-12-05 AR ARP020104720A patent/AR037713A1/es not_active Application Discontinuation
- 2002-12-05 PE PE2002001173A patent/PE20030641A1/es not_active Application Discontinuation
- 2002-12-05 TW TW091135282A patent/TWI249403B/zh not_active IP Right Cessation
- 2002-12-09 CA CA002469315A patent/CA2469315C/en not_active Expired - Fee Related
- 2002-12-09 DK DK02796109.3T patent/DK1455756T4/en active
- 2002-12-09 HR HRP20040532AA patent/HRP20040532B1/xx not_active IP Right Cessation
- 2002-12-09 IL IL16229602A patent/IL162296A0/xx unknown
- 2002-12-09 NZ NZ534009A patent/NZ534009A/xx not_active IP Right Cessation
- 2002-12-09 HU HU0402596A patent/HU230736B1/hu unknown
- 2002-12-09 ES ES02796109.3T patent/ES2307820T5/es not_active Expired - Lifetime
- 2002-12-09 US US10/317,948 patent/US8258132B2/en active Active
- 2002-12-09 AT AT02796109T patent/ATE400254T1/de active
- 2002-12-09 PL PL369887A patent/PL211243B6/pl unknown
- 2002-12-09 CN CNB028278143A patent/CN100352443C/zh not_active Expired - Lifetime
- 2002-12-09 WO PCT/US2002/041655 patent/WO2003049718A1/en not_active Ceased
- 2002-12-09 RS YU50404A patent/RS52280B/sr unknown
- 2002-12-09 GE GE5622A patent/GEP20063875B/en unknown
- 2002-12-09 SI SI200230707T patent/SI1455756T2/sl unknown
- 2002-12-09 BR BRPI0214786A patent/BRPI0214786B8/pt not_active IP Right Cessation
- 2002-12-09 KR KR10-2004-7008970A patent/KR20040063991A/ko not_active Ceased
- 2002-12-09 ME MEP-2008-684A patent/ME00450B/me unknown
- 2002-12-09 JP JP2003550767A patent/JP4532114B2/ja not_active Expired - Lifetime
- 2002-12-09 PT PT02796109T patent/PT1455756E/pt unknown
- 2002-12-09 MX MXPA04005563A patent/MXPA04005563A/es active IP Right Grant
- 2002-12-09 EP EP02796109.3A patent/EP1455756B2/en not_active Expired - Lifetime
- 2002-12-09 EA EA200400794A patent/EA007332B1/ru not_active IP Right Cessation
- 2002-12-09 DE DE60227556T patent/DE60227556D1/de not_active Expired - Lifetime
- 2002-12-09 AU AU2002360824A patent/AU2002360824B8/en not_active Expired
- 2002-12-10 DO DO2002000542A patent/DOP2002000542A/es unknown
2004
- 2004-05-21 IS IS7276A patent/IS2991B/is unknown
- 2004-05-24 ZA ZA2004/04012A patent/ZA200404012B/en unknown
- 2004-06-01 IL IL162296A patent/IL162296A/en active IP Right Grant
- 2004-06-08 EC EC2004005144A patent/ECSP045144A/es unknown
- 2004-06-09 CO CO04054198A patent/CO5590887A2/es not_active Application Discontinuation
- 2004-07-09 NO NO20042905A patent/NO336943B1/no not_active IP Right Cessation
2008
- 2008-09-17 CY CY20081101013T patent/CY1108354T1/el unknown
2009
- 2009-10-20 IL IL201658A patent/IL201658A0/en unknown

Also Published As

Publication number	Publication date
DOP2002000542A (es)	2003-07-15
ES2307820T3 (es)	2008-12-01
AU2002360824B2 (en)	2008-05-08
CY1108354T1 (el)	2012-05-23
CN1617712A (zh)	2005-05-18
NZ534009A (en)	2006-03-31
WO2003049718A1 (en)	2003-06-19
RS50404A (sr)	2007-04-10
EP1455756A1 (en)	2004-09-15
CA2469315C (en)	2008-12-02
CA2469315A1 (en)	2003-06-19
UA76810C2 (uk)	2006-09-15
DK1455756T3 (da)	2008-11-17
PL211243B1 (pl)	2012-04-30
EA200400794A1 (ru)	2004-10-28
HRP20040532B1 (en)	2012-09-30
NO336943B1 (no)	2015-11-30
BRPI0214786B1 (pt)	2018-11-27
IS7276A (is)	2004-05-21
JP2005516003A (ja)	2005-06-02
US20040214746A1 (en)	2004-10-28
JO3060B1 (ar)	2017-03-15
MXPA04005563A (es)	2004-12-06
CN100352443C (zh)	2007-12-05
AR037713A1 (es)	2004-12-01
EP1455756B1 (en)	2008-07-09
RS52280B (sr)	2012-10-31
IL162296A (en)	2013-11-28
NO20042905L (no)	2004-09-10
TWI249403B (en)	2006-02-21
BRPI0214786B8 (pt)	2021-05-25
PT1455756E (pt)	2008-10-16
GEP20063875B (en)	2006-07-10
ME00450B (me)	2011-10-10
ZA200404012B (en)	2005-10-26
BR0214786A (pt)	2004-11-09
AU2002360824A1 (en)	2003-06-23
CO5590887A2 (es)	2005-12-30
MY155911A (en)	2015-12-15
ES2307820T5 (es)	2016-01-13
DE60227556D1 (de)	2008-08-21
ECSP045144A (es)	2004-07-23
HU230736B1 (hu)	2018-01-29
KR20040063991A (ko)	2004-07-15
ATE400254T1 (de)	2008-07-15
PE20030641A1 (es)	2003-07-23
HRP20040532A2 (en)	2004-10-31
DK1455756T4 (en)	2016-01-04
AU2002360824B8 (en)	2008-05-22
JP4532114B2 (ja)	2010-08-25
PL211243B6 (pl)	2023-01-23
HK1078017A1 (zh)	2006-03-03
SI1455756T1 (sl)	2008-12-31
US8258132B2 (en)	2012-09-04
IL201658A0 (en)	2011-08-01
EA007332B1 (ru)	2006-08-25
SI1455756T2 (sl)	2016-01-29
PL369887A1 (en)	2005-05-02
HUP0402596A3 (en)	2011-05-30
HUP0402596A2 (hu)	2005-03-29
IL162296A0 (en)	2005-11-20
EP1455756B2 (en)	2015-09-23
TW200301125A (en)	2003-07-01

Publication	Publication Date	Title
IS2991B (is)	2017-12-15	Lyfjafræðileg nanóagna samsetning takykínín viðtakamótlyfs
EE200300284A (et)	2003-10-15	NMDA-retseptori agonisti farmatseutilised kompositsioonid
FI20011478L (fi)	2003-01-06	Farmaseuttinen koostumus
HUP0500443A3 (en)	2009-12-28	Himbacine analogues as thrombin receptor antagonists and pharmaceutical compositions containing them
PL367180A1 (pl)	2005-02-21	Trwała kompozycja farmaceutyczna
DE60201988D1 (de)	2004-12-23	Pharmazeutische dosierungsform von amorphem nilfenavir mesylat
NO20052739D0 (no)	2005-06-07	CCR5-antagonister som medikamenter
ATE336264T1 (de)	2006-09-15	Dispergierbare pharmazeutische zusammensetzungen
IS2580B (is)	2010-02-15	Platínuafleiða lyfjasamsetningar
NO20033785D0 (no)	2003-08-26	Farmasöytisk formulering
NO20033042D0 (no)	2003-07-02	Cyklodekstrin-inneholdende farmasöytisk preparat
EE200300589A (et)	2004-02-16	Ravimkoostised
DE60329755D1 (de)	2009-12-03	Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
FI20022128A7 (fi)	2003-06-06	Farmaseuttinen koostumus
DE60217390D1 (de)	2007-02-15	Bicalutamid enthaltende pharmazeutische zusammensetzung
ITMI20041963A1 (it)	2005-01-15	"antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche"
ATE370114T1 (de)	2007-09-15	Zwitterionische tachykinin-rezeptor-antagonisten
NO20043007L (no)	2004-07-15	Farmasoytisk suspensjon for oral administrering
NO20033162L (no)	2003-07-10	Farmasöytisk tablett omfattende paroksetinmesylat
DE10291905D2 (de)	2004-05-27	Pharmazeutische Zusammensetzung
PT1448566E (pt)	2006-08-31	Antagonistas do receptor quimioquina e metodos de utilizacao do mesmo
IL160438A0 (en)	2004-07-25	Pharmaceutical compositions containing an angiotensin ii receptor antagonist
AU2002328569A1 (en)	2003-06-05	Medicinal compositions containing angiotensin II receptor antagonist
DE10107261B4 (de)	2005-03-10	Pharmazeutische Zusammensetzung
DE60134427D1 (de)	2008-07-24	Exzitatorische aminosäure-rezeptor-antagonisten