IN2013MU02611A - - Google Patents
Download PDFInfo
- Publication number
- IN2013MU02611A IN2013MU02611A IN2611MU2013A IN2013MU02611A IN 2013MU02611 A IN2013MU02611 A IN 2013MU02611A IN 2611MU2013 A IN2611MU2013 A IN 2611MU2013A IN 2013MU02611 A IN2013MU02611 A IN 2013MU02611A
- Authority
- IN
- India
- Prior art keywords
- compounds
- diseases
- inhibitors
- janus kinase
- present
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- 108010024121 Janus Kinases Proteins 0.000 abstract 3
- 102000015617 Janus Kinases Human genes 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 210000000845 cartilage Anatomy 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010010356 Congenital anomaly Diseases 0.000 abstract 1
- 101000997835 Homo sapiens Tyrosine-protein kinase JAK1 Proteins 0.000 abstract 1
- 101000997832 Homo sapiens Tyrosine-protein kinase JAK2 Proteins 0.000 abstract 1
- 101000934996 Homo sapiens Tyrosine-protein kinase JAK3 Proteins 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 102100033438 Tyrosine-protein kinase JAK1 Human genes 0.000 abstract 1
- 102100033444 Tyrosine-protein kinase JAK2 Human genes 0.000 abstract 1
- 102100025387 Tyrosine-protein kinase JAK3 Human genes 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 229940047124 interferons Drugs 0.000 abstract 1
- 230000036244 malformation Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000007306 turnover Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/910,028 US9556148B2 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
| HUE14793899A HUE033448T2 (en) | 2013-08-07 | 2014-08-06 | Janus kinase inhibitor N-cyanomethylamides |
| HK16110100.8A HK1222386A1 (zh) | 2013-08-07 | 2014-08-06 | 作爲詹纳斯激酶的抑制剂的n-氰基甲基酰胺 |
| JP2016517296A JP2016525071A (ja) | 2013-08-07 | 2014-08-06 | ヤーヌスキナーゼのインヒビターとしてのｎ−シアノメチルアミド |
| PCT/IN2014/000515 WO2015019365A1 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
| HRP20170277TT HRP20170277T1 (hr) | 2013-08-07 | 2014-08-06 | N-cijanometilamidi kao inhibitori janus kinaze |
| IN2611MU2013 IN2013MU02611A (no) | 2013-08-07 | 2014-08-06 | |
| TW103126910A TWI562990B (en) | 2013-08-07 | 2014-08-06 | Novel compounds as inhibitors of janus kinase |
| CN201480054915.9A CN105612154A (zh) | 2013-08-07 | 2014-08-06 | 作为詹纳斯激酶的抑制剂的n-氰基甲基酰胺 |
| PL14793899T PL3030561T3 (pl) | 2013-08-07 | 2014-08-06 | N-cyjanometyloamidy jako inhibitory kinaz janusowych |
| ES14793899.7T ES2618072T3 (es) | 2013-08-07 | 2014-08-06 | N-Cianometilamidas como inhibidores de la quinasa Janus |
| EP14793899.7A EP3030561B1 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
| PT147938997T PT3030561T (pt) | 2013-08-07 | 2014-08-06 | N-cianometilamidas como inibidores de cinase janus |
| DK14793899.7T DK3030561T3 (en) | 2013-08-07 | 2014-08-06 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE |
| KR1020167005187A KR101665301B1 (ko) | 2013-08-07 | 2014-08-06 | 야누스 키나제의 억제제로서 n-시아노메틸아미드 |
| ARP140102982A AR097282A1 (es) | 2013-08-07 | 2014-08-07 | Compuestos como inhibidores de la janus quinasa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2611MU2013 IN2013MU02611A (no) | 2013-08-07 | 2014-08-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU02611A true IN2013MU02611A (no) | 2015-06-12 |
Family
ID=54199342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2611MU2013 IN2013MU02611A (no) | 2013-08-07 | 2014-08-06 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9556148B2 (no) |
| EP (1) | EP3030561B1 (no) |
| JP (1) | JP2016525071A (no) |
| KR (1) | KR101665301B1 (no) |
| CN (1) | CN105612154A (no) |
| AR (1) | AR097282A1 (no) |
| DK (1) | DK3030561T3 (no) |
| ES (1) | ES2618072T3 (no) |
| HK (1) | HK1222386A1 (no) |
| HR (1) | HRP20170277T1 (no) |
| HU (1) | HUE033448T2 (no) |
| IN (1) | IN2013MU02611A (no) |
| PL (1) | PL3030561T3 (no) |
| PT (1) | PT3030561T (no) |
| TW (1) | TWI562990B (no) |
| WO (1) | WO2015019365A1 (no) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105801910A (zh) * | 2016-06-01 | 2016-07-27 | 扬州兰都塑料科技有限公司 | 一种电力电缆阻燃助剂 |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1286302B1 (it) | 1996-04-10 | 1998-07-08 | Rotta Research Lab | Chinazoline-4-amino-2-(piperidino-1-il-4-sostituite) ad attivita' anti-ipertensiva, procedimento per la loro preparazione e loro uso |
| KR100882544B1 (ko) | 1999-05-24 | 2009-02-12 | 미쓰비시 타나베 파마 코퍼레이션 | 페녹시프로필아민 화합물 |
| GB0012240D0 (en) | 2000-05-19 | 2000-07-12 | Merck Sharp & Dohme | Therapeutic agents |
| WO2002036562A2 (en) | 2000-11-02 | 2002-05-10 | Wyeth | 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands |
| TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
| DE10250708A1 (de) | 2002-10-31 | 2004-05-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| ITMI20040954A1 (it) | 2004-05-12 | 2004-08-12 | Univ Degli Studi Milano | Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica |
| EP2360474B1 (en) | 2004-06-21 | 2013-07-24 | Galapagos N.V. | Methods and means for treatment of osteoarthritis |
| JP4624315B2 (ja) | 2005-12-20 | 2011-02-02 | 株式会社リヒトラブ | 綴じ具 |
| US8440663B2 (en) | 2006-01-30 | 2013-05-14 | Exelixis, Inc. | 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrimidines as JAK-2 modulators and methods of use |
| WO2008060621A2 (en) | 2006-11-17 | 2008-05-22 | Abbott Laboratories | Aminopyrrolidines as chemokine receptor antagonists |
| HRP20151386T1 (hr) | 2007-03-12 | 2016-02-26 | Ym Biosciences Australia Pty Ltd | Fenil aminopirimidinski spojevi i njihova primjena |
| US8242271B2 (en) | 2007-06-04 | 2012-08-14 | Avila Therapeutics, Inc. | Heterocyclic compounds and uses thereof |
| WO2009029998A1 (en) | 2007-09-06 | 2009-03-12 | Cytopia Research Pty Ltd | Retrometabolic compounds |
| US8178692B2 (en) | 2007-09-19 | 2012-05-15 | Albemarle Corporation | Methods for production of 1,2,4-triazol-3-one |
| CA2920996A1 (en) | 2007-10-19 | 2009-04-23 | Celgene Avilomics Research, Inc. | Heteroaryl compounds and uses thereof |
| US7989465B2 (en) | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
| JP5711537B2 (ja) | 2008-02-15 | 2015-05-07 | ライジェル ファーマシューティカルズ， インコーポレイテッド | ピリミジン−２−アミン化合物およびｊａｋキナーゼの阻害剤としてのその使用 |
| KR20100132550A (ko) | 2008-04-16 | 2010-12-17 | 포톨라 파마슈티컬스, 인코포레이티드 | ｓｙｋ 또는 ＪＡＫ 키나제 억제제로서의 ２,６－디아미노-피리미딘－５－일－카르복스아미드 |
| CN102066340B (zh) | 2008-04-16 | 2014-05-14 | 波托拉医药品公司 | 作为syk或jak蛋白激酶抑制剂的2,6-二氨基-嘧啶-5-基甲酰胺类化合物 |
| NZ589843A (en) | 2008-06-27 | 2012-12-21 | Avila Therapeutics Inc | Pyrimidine heteroaryl compounds and uses thereof as protein kinase inhibitors |
| EP2344476B1 (en) | 2008-09-23 | 2015-04-29 | Rigel Pharmaceuticals, Inc. | Tricyclic carbamate jak inhibitors |
| US8268851B2 (en) | 2008-12-23 | 2012-09-18 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the JAK pathway |
| US8278299B2 (en) | 2008-12-30 | 2012-10-02 | Rigel Pharmaceuticals, Inc. | Pyrimidinediamine kinase inhibitors |
| SG172885A1 (en) | 2009-01-23 | 2011-08-29 | Rigel Pharmaceuticals Inc | Compositions and methods for inhibition of the jak pathway |
| US8367689B2 (en) | 2009-05-06 | 2013-02-05 | Portola Pharmaceuticals, Inc. | Inhibitors of JAK |
| JP5449540B2 (ja) | 2009-06-05 | 2014-03-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規化合物 |
| WO2011017178A1 (en) | 2009-07-28 | 2011-02-10 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| DE102010003599A1 (de) | 2010-04-01 | 2011-10-06 | Lisa Dräxlmaier GmbH | Verfahren zur Kabelkonfektionierung sowie konfektioniertes Kabel |
| WO2013010453A1 (en) | 2011-07-15 | 2013-01-24 | Abbott Laboratories | Chemoking receptor antagonists |
| WO2013093940A1 (en) | 2011-12-20 | 2013-06-27 | Council Of Scientific & Industrial Research | Nitrofurfuryl substituted phenyl linked piperidino-oxadiazoline conjugates as anti-tubercular agents and process for the preparation thereof |
| WO2013139717A1 (en) | 2012-03-19 | 2013-09-26 | Smardtv S.A. | A cicam system for processing multiple programme transport streams |
-
2014
- 2014-08-06 IN IN2611MU2013 patent/IN2013MU02611A/en unknown
- 2014-08-06 PL PL14793899T patent/PL3030561T3/pl unknown
- 2014-08-06 ES ES14793899.7T patent/ES2618072T3/es active Active
- 2014-08-06 KR KR1020167005187A patent/KR101665301B1/ko not_active Expired - Fee Related
- 2014-08-06 HK HK16110100.8A patent/HK1222386A1/zh unknown
- 2014-08-06 JP JP2016517296A patent/JP2016525071A/ja not_active Ceased
- 2014-08-06 HU HUE14793899A patent/HUE033448T2/en unknown
- 2014-08-06 EP EP14793899.7A patent/EP3030561B1/en not_active Not-in-force
- 2014-08-06 US US14/910,028 patent/US9556148B2/en not_active Expired - Fee Related
- 2014-08-06 TW TW103126910A patent/TWI562990B/zh not_active IP Right Cessation
- 2014-08-06 PT PT147938997T patent/PT3030561T/pt unknown
- 2014-08-06 HR HRP20170277TT patent/HRP20170277T1/hr unknown
- 2014-08-06 DK DK14793899.7T patent/DK3030561T3/en active
- 2014-08-06 CN CN201480054915.9A patent/CN105612154A/zh active Pending
- 2014-08-06 WO PCT/IN2014/000515 patent/WO2015019365A1/en not_active Ceased
- 2014-08-07 AR ARP140102982A patent/AR097282A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101665301B1 (ko) | 2016-10-11 |
| KR20160030580A (ko) | 2016-03-18 |
| WO2015019365A1 (en) | 2015-02-12 |
| JP2016525071A (ja) | 2016-08-22 |
| PT3030561T (pt) | 2017-03-23 |
| PL3030561T3 (pl) | 2017-08-31 |
| TWI562990B (en) | 2016-12-21 |
| EP3030561B1 (en) | 2017-01-11 |
| DK3030561T3 (en) | 2017-03-27 |
| EP3030561A1 (en) | 2016-06-15 |
| TW201518290A (zh) | 2015-05-16 |
| HUE033448T2 (en) | 2017-11-28 |
| ES2618072T3 (es) | 2017-06-20 |
| HRP20170277T1 (hr) | 2017-05-19 |
| AR097282A1 (es) | 2016-03-02 |
| WO2015019365A8 (en) | 2016-02-18 |
| HK1222386A1 (zh) | 2017-06-30 |
| US20160176849A1 (en) | 2016-06-23 |
| CN105612154A (zh) | 2016-05-25 |
| US9556148B2 (en) | 2017-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12018502125A1 (en) | Bipyrazole derivatives as jak inhibitors | |
| PH12020500195A1 (en) | Pyrimidinones as factor xia inhibitors | |
| PH12014502615B1 (en) | Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof | |
| MX2011012353A (es) | Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo[2, 3-d]pirimidinas y pirrol-3-il-pirrolo[2,3-d]pirimidinas como inhibidores de la cinasa janus. | |
| MX2016007371A (es) | Compuesto de 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]pirazolo[1, 5-a]pirimidin-3-carboxamida util como inhibidor de cinasa de ataxia telangiectasia mutada (atm) y rad3 relacionados (atr), su preparacion, diferentes formas solidas y sus derivados radiomarcados. | |
| MY155639A (en) | 2, 6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinases inhibitors | |
| EA033497B1 (ru) | 1-(тиофенил или фенил)сульфонил-(пирролидин)-2-карбоксамидные производные и их применение в качестве антагонистов trpa1 | |
| MD4735B1 (ro) | Derivaţi ai pirolo[2,3-d]pirimidinei ca inhibitori de Kinaze Janus-asociate (JAK) | |
| JOP20190174B1 (ar) | مثبطات jak1 انتقائية | |
| PH12013500648A1 (en) | Quinazolin-4 (3h) -one derivatives used as pi3 kinase inhibitors | |
| GEP20227344B (en) | Pyrimidine compound as jak kinase inhibitor | |
| MX341577B (es) | Derivados biciclicos de pirimidin-urea o carbamato sustituidos con morfolino como inhibidores del blanco de rapamicina de mamifero. | |
| NZ725001A (en) | Tricyclic compound and jak inhibitor | |
| PH12014502538A1 (en) | Amorphous form of an akt inhibiting pyrimidinyl - cyclopentane compound, compositions and methods tehreof | |
| HK1213181A1 (zh) | 雙環氧雜內酰胺激酶抑制劑 | |
| IN2013MU02611A (no) | ||
| NZ748942A (en) | Pyrazolylaminobenzimidazole derivatives as jak inhibitors | |
| MY192305A (en) | Bipyrazole derivatives as jak inhibitors | |
| TN2010000471A1 (en) | 2-6 diamino pyrimidin 5-yl carboxamides as syk or jak kinases inhibitors | |
| HK1228397A1 (en) | Protein kinase inhibitors |