ID26504A - Turunan-turunan asam indolil-3-glioksilat yang memiliki aksi anti tumor - Google Patents

Turunan-turunan asam indolil-3-glioksilat yang memiliki aksi anti tumor

Info

Publication number: ID26504A
Authority: ID; Indonesia
Prior art keywords: glyoxicate; indolil; anti tumor; tumor action; acid drops
Prior art date: 1998-04-02

Application number

IDW20001988A

Other languages

English (en)

Indonesian (id)

Inventor

Bernd Nickel

Istvan Szelenyl

Jurgen Schmidt

Peter Emig

Dietmar Reichert

Eckhard Gunther

Kay Brune

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-02

Filing date

1999-03-22

Publication date

2001-01-11

1999-03-22 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

2001-01-11 Publication of ID26504A publication Critical patent/ID26504A/id

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)

IDW20001988A 1998-04-02 1999-03-22 Turunan-turunan asam indolil-3-glioksilat yang memiliki aksi anti tumor ID26504A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19814838A DE19814838C2 (de)	1998-04-02	1998-04-02	Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung

Publications (1)

Publication Number	Publication Date
ID26504A true ID26504A (id)	2001-01-11

Family

ID=7863398

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20001988A ID26504A (id)	1998-04-02	1999-03-22	Turunan-turunan asam indolil-3-glioksilat yang memiliki aksi anti tumor

Country Status (32)

Country	Link
US (4)	US6232327B1 (fr)
EP (1)	EP1071420B1 (fr)
JP (2)	JP5253696B2 (fr)
KR (1)	KR100583545B1 (fr)
CN (1)	CN1148183C (fr)
AR (1)	AR018175A1 (fr)
AT (1)	ATE304352T1 (fr)
AU (1)	AU768510B2 (fr)
BG (1)	BG64838B1 (fr)
BR (1)	BR9909902A (fr)
CA (1)	CA2326833C (fr)
DE (2)	DE19814838C2 (fr)
DK (1)	DK1071420T3 (fr)
EE (1)	EE04354B1 (fr)
ES (1)	ES2249884T3 (fr)
GE (1)	GEP20032967B (fr)
HR (1)	HRP20000643A2 (fr)
HU (1)	HUP0101530A3 (fr)
ID (1)	ID26504A (fr)
IL (2)	IL138737A0 (fr)
IS (1)	IS2307B (fr)
NO (1)	NO327721B1 (fr)
NZ (1)	NZ507084A (fr)
PL (1)	PL192779B1 (fr)
RS (1)	RS49866B (fr)
RU (1)	RU2262339C2 (fr)
SK (1)	SK286393B6 (fr)
TR (1)	TR200002853T2 (fr)
TW (1)	TWI230608B (fr)
UA (1)	UA70942C2 (fr)
WO (1)	WO1999051224A1 (fr)
ZA (1)	ZA200006150B (fr)

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US9353150B2 (en)	2012-12-04	2016-05-31	Massachusetts Institute Of Technology	Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
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1998
- 1998-04-02 DE DE19814838A patent/DE19814838C2/de not_active Expired - Fee Related
1999
- 1999-03-22 WO PCT/EP1999/001918 patent/WO1999051224A1/fr not_active Ceased
- 1999-03-22 ID IDW20001988A patent/ID26504A/id unknown
- 1999-03-22 CA CA002326833A patent/CA2326833C/fr not_active Expired - Fee Related
- 1999-03-22 JP JP2000541995A patent/JP5253696B2/ja not_active Expired - Fee Related
- 1999-03-22 CN CNB998059234A patent/CN1148183C/zh not_active Expired - Fee Related
- 1999-03-22 AT AT99910372T patent/ATE304352T1/de active
- 1999-03-22 ES ES99910372T patent/ES2249884T3/es not_active Expired - Lifetime
- 1999-03-22 SK SK1430-2000A patent/SK286393B6/sk not_active IP Right Cessation
- 1999-03-22 BR BR9909902-0A patent/BR9909902A/pt not_active IP Right Cessation
- 1999-03-22 EE EEP200000581A patent/EE04354B1/xx not_active IP Right Cessation
- 1999-03-22 EP EP99910372A patent/EP1071420B1/fr not_active Expired - Lifetime
- 1999-03-22 RU RU2000128035/15A patent/RU2262339C2/ru not_active IP Right Cessation
- 1999-03-22 RS YUP-593/00A patent/RS49866B/sr unknown
- 1999-03-22 NZ NZ507084A patent/NZ507084A/en not_active IP Right Cessation
- 1999-03-22 KR KR1020007010934A patent/KR100583545B1/ko not_active Expired - Fee Related
- 1999-03-22 DK DK99910372T patent/DK1071420T3/da active
- 1999-03-22 HR HR20000643A patent/HRP20000643A2/hr not_active Application Discontinuation
- 1999-03-22 AU AU29349/99A patent/AU768510B2/en not_active Ceased
- 1999-03-22 IL IL13873799A patent/IL138737A0/xx active IP Right Grant
- 1999-03-22 GE GEAP19995611A patent/GEP20032967B/en unknown
- 1999-03-22 HU HU0101530A patent/HUP0101530A3/hu unknown
- 1999-03-22 UA UA2000116192A patent/UA70942C2/uk unknown
- 1999-03-22 PL PL343525A patent/PL192779B1/pl unknown
- 1999-03-22 TR TR2000/02853T patent/TR200002853T2/xx unknown
- 1999-03-22 DE DE59912562T patent/DE59912562D1/de not_active Expired - Lifetime
- 1999-03-23 TW TW088104599A patent/TWI230608B/zh not_active IP Right Cessation
- 1999-03-31 AR ARP990101501A patent/AR018175A1/es unknown
- 1999-04-02 US US09/285,058 patent/US6232327B1/en not_active Expired - Lifetime
2000
- 2000-09-22 IS IS5635A patent/IS2307B/is unknown
- 2000-09-27 IL IL138737A patent/IL138737A/en not_active IP Right Cessation
- 2000-09-29 NO NO20004916A patent/NO327721B1/no not_active IP Right Cessation
- 2000-10-12 BG BG104849A patent/BG64838B1/bg unknown
- 2000-10-31 ZA ZA200006150A patent/ZA200006150B/en unknown
2001
- 2001-03-19 US US09/810,604 patent/US20030023093A1/en not_active Abandoned
2002
- 2002-12-04 US US10/309,204 patent/US7579365B2/en not_active Expired - Fee Related
2007
- 2007-08-20 US US11/894,591 patent/US20080027110A1/en not_active Abandoned
2011
- 2011-03-10 JP JP2011053448A patent/JP2011148809A/ja active Pending

Also Published As

Publication number	Publication date
BG64838B1 (bg)	2006-06-30
SK286393B6 (sk)	2008-09-05
AU768510B2 (en)	2003-12-18
ATE304352T1 (de)	2005-09-15
KR20010042368A (ko)	2001-05-25
TR200002853T2 (tr)	2001-02-21
ES2249884T3 (es)	2006-04-01
HUP0101530A3 (en)	2002-12-28
NO327721B1 (no)	2009-09-14
US6232327B1 (en)	2001-05-15
BG104849A (en)	2001-05-31
US7579365B2 (en)	2009-08-25
DE19814838C2 (de)	2001-01-18
HRP20000643A2 (en)	2001-04-30
CN1148183C (zh)	2004-05-05
AR018175A1 (es)	2001-10-31
IL138737A (en)	2007-02-11
JP5253696B2 (ja)	2013-07-31
YU59300A (sh)	2002-11-15
RU2262339C2 (ru)	2005-10-20
JP2002510622A (ja)	2002-04-09
IS5635A (is)	2000-09-22
HK1036408A1 (en)	2002-01-04
AU2934999A (en)	1999-10-25
CA2326833A1 (fr)	1999-10-14
KR100583545B1 (ko)	2006-05-26
WO1999051224A1 (fr)	1999-10-14
UA70942C2 (uk)	2004-11-15
US20030195360A1 (en)	2003-10-16
EE200000581A (et)	2002-02-15
BR9909902A (pt)	2000-12-26
SK14302000A3 (sk)	2001-11-06
JP2011148809A (ja)	2011-08-04
CA2326833C (fr)	2009-06-23
NO20004916D0 (no)	2000-09-29
ZA200006150B (en)	2001-01-11
TWI230608B (en)	2005-04-11
US20030023093A1 (en)	2003-01-30
DE19814838A1 (de)	1999-10-14
EP1071420B1 (fr)	2005-09-14
GEP20032967B (en)	2003-05-27
EE04354B1 (et)	2004-10-15
HUP0101530A2 (hu)	2001-11-28
PL192779B1 (pl)	2006-12-29
NZ507084A (en)	2003-10-31
PL343525A1 (en)	2001-08-27
NO20004916L (no)	2000-12-01
US20080027110A1 (en)	2008-01-31
DE59912562D1 (en)	2005-10-20
EP1071420A1 (fr)	2001-01-31
DK1071420T3 (da)	2006-01-16
RS49866B (sr)	2008-08-07
IS2307B (is)	2007-10-15
IL138737A0 (en)	2001-10-31
CN1299280A (zh)	2001-06-13

Publication	Publication Date	Title
ID26504A (id)	2001-01-11	Turunan-turunan asam indolil-3-glioksilat yang memiliki aksi anti tumor
ID28833A (id)	2001-07-05	Turunan asam 3-aril-2-hidroksipropionat
ID26222A (id)	2000-12-07	Hidroksamida asam(4-arilsulfonilamino)-tetrahidropiran-4-karboksilat
ID23668A (id)	2000-05-11	Turunan asam ariloksiarilsulfonilamino hidroksamat
ID22095A (id)	1999-09-02	Asam aril-akrilat ester
ID26819A (id)	2001-02-15	Turunan imidazo piridina yang menghambat sekresi asam lambung
ID20809A (id)	1999-03-11	Asam diaminokarboksilat tersubstitusi
ID20807A (id)	1999-03-11	Asam sulfonilaminokarboksilat
ID27562A (id)	2001-04-12	Turunan-turunan kinolin-2-ona tersubstitusi alkunil yang berguna sebagai zat anti kanker
ID24376A (id)	2000-07-13	Turunan-turunan asam amidokarboksilat
ID28699A (id)	2001-06-28	Turunan-turunan asam oksiiminoalkanoat
NO991436L (no)	1999-09-27	Tilknytningskobling
ID26978A (id)	2001-02-22	Turunan-turunan asam aminometilkarboksilat
ID30181A (id)	2001-11-08	Asam antranilat- dan asam tioantranilat-n-aril amida
ID28164A (id)	2001-05-10	Turunan iii asam 3-aril-2-hidroksipropionat baru
ID27006A (id)	2001-02-22	Turunan-turunan isotiazol yang bermanfaat sebagai zat anti kanker
ATE269861T1 (de)	2004-07-15	Substituierte indolalkansäure
DE60007945D1 (de)	2004-03-04	Schwimmend montierte Verbinderanordnung
ID20500A (id)	1998-12-31	Metoda untuk memperoleh asam akrilat
ID29584A (id)	2001-09-06	Turunan-turunan kuinolin-2-on tersubstitusi heteroaril yang bermanfaat sebagai zat-zat anti kanker
ID27584A (id)	2001-04-12	Katalis kompleks sianida logam ganda yang diperlakukan dengan asam
ID23502A (id)	2000-04-27	Pembuatan asam tereftalat
ID29876A (id)	2001-10-18	Komposisi yang mengandung asam difosfonat
DE69913252D1 (de)	2004-01-15	Schwimmende Steckeranordnung
DE69936956D1 (de)	2007-10-11	Kartenverbinder