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HUE066262T2 - Ösztrogén-rokon alfa receptor (EER-alfa) modulátorok - Google Patents

Ösztrogén-rokon alfa receptor (EER-alfa) modulátorok

Info

Publication number
HUE066262T2
HUE066262T2 HUE20792415A HUE20792415A HUE066262T2 HU E066262 T2 HUE066262 T2 HU E066262T2 HU E20792415 A HUE20792415 A HU E20792415A HU E20792415 A HUE20792415 A HU E20792415A HU E066262 T2 HUE066262 T2 HU E066262T2
Authority
HU
Hungary
Prior art keywords
alpha
err
estrogen
modulators
related receptor
Prior art date
Application number
HUE20792415A
Other languages
English (en)
Inventor
Jaap Gerardus Henricus Lemmers
Eugen Deretey
Johannes Petrus Gerardus Klomp
Joseph Maria Gerardus Cals
Arthur Oubrie
Original Assignee
Lead Pharma Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Pharma Holding Bv filed Critical Lead Pharma Holding Bv
Publication of HUE066262T2 publication Critical patent/HUE066262T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
HUE20792415A 2019-10-18 2020-10-16 Ösztrogén-rokon alfa receptor (EER-alfa) modulátorok HUE066262T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19204189 2019-10-18

Publications (1)

Publication Number Publication Date
HUE066262T2 true HUE066262T2 (hu) 2024-07-28

Family

ID=68296174

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE20792415A HUE066262T2 (hu) 2019-10-18 2020-10-16 Ösztrogén-rokon alfa receptor (EER-alfa) modulátorok

Country Status (20)

Country Link
US (1) US20240150342A1 (hu)
EP (1) EP4045503B1 (hu)
JP (1) JP7629912B2 (hu)
KR (1) KR20220084355A (hu)
CN (1) CN114630827B (hu)
AU (1) AU2020365434A1 (hu)
BR (1) BR112022006906A2 (hu)
CA (1) CA3151045A1 (hu)
CO (1) CO2022003829A2 (hu)
ES (1) ES2970386T3 (hu)
HR (1) HRP20240237T1 (hu)
HU (1) HUE066262T2 (hu)
IL (1) IL291523B2 (hu)
MA (1) MA57379B1 (hu)
MX (1) MX2022004394A (hu)
PH (1) PH12022550627A1 (hu)
PL (1) PL4045503T3 (hu)
RS (1) RS64986B1 (hu)
WO (1) WO2021074365A1 (hu)
ZA (1) ZA202203025B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024001594A (es) * 2021-08-03 2024-02-15 Beigene Ltd Compuestos de pirazolopiridinona.
WO2023165504A1 (en) 2022-03-01 2023-09-07 Insilico Medicine Ip Limited Diacylglycerol kinase (dgk) alpha inhibitors and uses thereof
WO2023165525A1 (en) * 2022-03-01 2023-09-07 Insilico Medicine Ip Limited Diacylglycerol kinase (dgk) alpha inhibitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ579372A (en) 2007-03-07 2012-02-24 Janssen Pharmaceutica Nv Substituted phenoxy thiazolidinediones as estrogen related receptor-alpha modulators
EP2789614B1 (en) * 2009-08-11 2017-04-26 Bristol-Myers Squibb Company Azaindazoles as Btk kinase modulators and use thereof
EP2970264A1 (en) * 2013-03-14 2016-01-20 AbbVie Inc. Pyrrolo[2,3-b]pyridine cdk9 kinase inhibitors

Also Published As

Publication number Publication date
CN114630827A (zh) 2022-06-14
MX2022004394A (es) 2022-05-18
IL291523B1 (en) 2023-08-01
AU2020365434A1 (en) 2022-05-26
RS64986B1 (sr) 2024-01-31
ES2970386T3 (es) 2024-05-28
CN114630827B (zh) 2024-09-03
US20240150342A1 (en) 2024-05-09
BR112022006906A2 (pt) 2022-07-05
CO2022003829A2 (es) 2022-07-08
MA57379B1 (fr) 2024-02-29
JP7629912B2 (ja) 2025-02-14
IL291523B2 (en) 2023-12-01
IL291523A (en) 2022-05-01
EP4045503A1 (en) 2022-08-24
JP2023501081A (ja) 2023-01-18
HRP20240237T1 (hr) 2024-05-10
ZA202203025B (en) 2023-12-20
PH12022550627A1 (en) 2023-03-13
PL4045503T3 (pl) 2024-05-06
EP4045503C0 (en) 2023-12-06
CA3151045A1 (en) 2021-04-22
KR20220084355A (ko) 2022-06-21
WO2021074365A1 (en) 2021-04-22
EP4045503B1 (en) 2023-12-06

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