GT201000137A - Tratamiento de cáncer de útero y cáncer de ovario con un inhibidor de parp solo en combinacion con agentes antitumorales. - Google Patents
Tratamiento de cáncer de útero y cáncer de ovario con un inhibidor de parp solo en combinacion con agentes antitumorales.Info
- Publication number
- GT201000137A GT201000137A GT201000137A GT201000137A GT201000137A GT 201000137 A GT201000137 A GT 201000137A GT 201000137 A GT201000137 A GT 201000137A GT 201000137 A GT201000137 A GT 201000137A GT 201000137 A GT201000137 A GT 201000137A
- Authority
- GT
- Guatemala
- Prior art keywords
- cancer
- treatment
- combination
- parp inhibitor
- antitumor agents
- Prior art date
Links
- 239000012661 PARP inhibitor Substances 0.000 title abstract 2
- 229940121906 Poly ADP ribose polymerase inhibitor Drugs 0.000 title abstract 2
- 206010033128 Ovarian cancer Diseases 0.000 title 1
- 206010061535 Ovarian neoplasm Diseases 0.000 title 1
- 208000002495 Uterine Neoplasms Diseases 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 206010046766 uterine cancer Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A LA UTILIZACIÓN DE INHIBIDOR DE PARP EN CUADROS DE CÁNCER ESPECIALMENTE LOCALIZADO EN EL OVARIO Y ÚTERO EL CUAL REPRESENTA LA QUINTA CAUSA DE MUERTE EN MUJERES POR LO DIFICIL DE DETECTAR EN SUS ETAPAS TEMPRANAS.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98733507P | 2007-11-12 | 2007-11-12 | |
| US1236407P | 2007-12-07 | 2007-12-07 | |
| US5852808P | 2008-06-03 | 2008-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT201000137A true GT201000137A (es) | 2012-04-23 |
Family
ID=40623903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT201000137A GT201000137A (es) | 2007-11-12 | 2010-05-11 | Tratamiento de cáncer de útero y cáncer de ovario con un inhibidor de parp solo en combinacion con agentes antitumorales. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20090123419A1 (es) |
| EP (1) | EP2217244A4 (es) |
| JP (1) | JP2011503071A (es) |
| KR (1) | KR20100102607A (es) |
| CN (1) | CN101918003A (es) |
| AU (1) | AU2008321382A1 (es) |
| CA (1) | CA2705417A1 (es) |
| CO (1) | CO6290649A2 (es) |
| CR (1) | CR11486A (es) |
| DO (2) | DOP2010000142A (es) |
| EC (1) | ECSP10010235A (es) |
| GT (1) | GT201000137A (es) |
| IL (1) | IL205633A0 (es) |
| MA (1) | MA32748B1 (es) |
| MX (1) | MX2010005221A (es) |
| NI (1) | NI201000084A (es) |
| NZ (1) | NZ586123A (es) |
| SG (1) | SG185954A1 (es) |
| TN (1) | TN2010000209A1 (es) |
| WO (1) | WO2009064444A2 (es) |
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| WO2008030891A2 (en) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Inhibition of fatty acid synthesis by parp inhibitors and methods of treatment thereof |
| WO2008030883A2 (en) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Treatment of cancer |
| WO2008030887A2 (en) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Methods for designing parp inhibitors and uses thereof |
| US7538252B2 (en) * | 2006-09-05 | 2009-05-26 | Bipar Sciences, Inc. | Drug design for tubulin inhibitors, compositions, and methods of treatment thereof |
| NZ586125A (en) * | 2007-11-12 | 2012-12-21 | Bipar Sciences Inc | Treatment of breast cancer with a parp inhibitor alone or in combination with anti-tumor agents |
| WO2009064444A2 (en) * | 2007-11-12 | 2009-05-22 | Bipar Sciences, Inc. | Treatment of uterine cancer and ovarian cancer with a parp inhibitor alone or in combination with anti-tumor agents |
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-
2008
- 2008-11-12 WO PCT/US2008/012757 patent/WO2009064444A2/en not_active Ceased
- 2008-11-12 US US12/269,833 patent/US20090123419A1/en not_active Abandoned
- 2008-11-12 AU AU2008321382A patent/AU2008321382A1/en not_active Withdrawn
- 2008-11-12 CN CN2008801245418A patent/CN101918003A/zh not_active Withdrawn
- 2008-11-12 EP EP08848605A patent/EP2217244A4/en not_active Withdrawn
- 2008-11-12 MX MX2010005221A patent/MX2010005221A/es unknown
- 2008-11-12 NZ NZ586123A patent/NZ586123A/xx not_active IP Right Cessation
- 2008-11-12 JP JP2010533126A patent/JP2011503071A/ja not_active Abandoned
- 2008-11-12 SG SG2012081592A patent/SG185954A1/en unknown
- 2008-11-12 KR KR1020107012840A patent/KR20100102607A/ko not_active Withdrawn
- 2008-11-12 CA CA2705417A patent/CA2705417A1/en not_active Withdrawn
-
2009
- 2009-07-14 US US12/502,943 patent/US20100009930A1/en not_active Abandoned
-
2010
- 2010-05-09 IL IL205633A patent/IL205633A0/en unknown
- 2010-05-11 TN TN2010000209A patent/TN2010000209A1/fr unknown
- 2010-05-11 GT GT201000137A patent/GT201000137A/es unknown
- 2010-05-11 NI NI201000084A patent/NI201000084A/es unknown
- 2010-05-12 DO DO2010000142A patent/DOP2010000142A/es unknown
- 2010-06-07 EC EC2010010235A patent/ECSP10010235A/es unknown
- 2010-06-10 CR CR11486A patent/CR11486A/es unknown
- 2010-06-11 MA MA32905A patent/MA32748B1/fr unknown
- 2010-06-11 CO CO10070932A patent/CO6290649A2/es not_active Application Discontinuation
-
2012
- 2012-11-16 DO DO2012000290A patent/DOP2012000290A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR11486A (es) | 2013-08-09 |
| MX2010005221A (es) | 2010-09-28 |
| DOP2010000142A (es) | 2010-07-31 |
| DOP2012000290A (es) | 2013-03-31 |
| ECSP10010235A (es) | 2010-07-30 |
| TN2010000209A1 (en) | 2011-11-11 |
| SG185954A1 (en) | 2012-12-28 |
| CA2705417A1 (en) | 2009-05-22 |
| WO2009064444A9 (en) | 2009-07-02 |
| MA32748B1 (fr) | 2011-11-01 |
| EP2217244A4 (en) | 2011-08-31 |
| CN101918003A (zh) | 2010-12-15 |
| US20100009930A1 (en) | 2010-01-14 |
| WO2009064444A2 (en) | 2009-05-22 |
| KR20100102607A (ko) | 2010-09-24 |
| NZ586123A (en) | 2012-12-21 |
| EP2217244A2 (en) | 2010-08-18 |
| IL205633A0 (en) | 2010-11-30 |
| NI201000084A (es) | 2011-04-27 |
| CO6290649A2 (es) | 2011-06-20 |
| AU2008321382A1 (en) | 2009-05-22 |
| US20090123419A1 (en) | 2009-05-14 |
| JP2011503071A (ja) | 2011-01-27 |
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