GB903256A - Improvements in novel otologic preparations and the process for their preparation - Google Patents
Improvements in novel otologic preparations and the process for their preparationInfo
- Publication number
- GB903256A GB903256A GB3832958A GB3832958A GB903256A GB 903256 A GB903256 A GB 903256A GB 3832958 A GB3832958 A GB 3832958A GB 3832958 A GB3832958 A GB 3832958A GB 903256 A GB903256 A GB 903256A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- fatty acid
- preparation
- novel
- hygroscopic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical group [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 abstract 1
- 229940124326 anaesthetic agent Drugs 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940064004 antiseptic throat preparations Drugs 0.000 abstract 1
- 239000003212 astringent agent Substances 0.000 abstract 1
- 239000002415 cerumenolytic agent Substances 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A cerumenolytic preparation comprises a hygroscopic aqueous-miscible solvent non-toxic to the ear and a protein-fatty acid condensate in the form of a salt of N-acylated polypeptides of formula <FORM:0903256/VI/1> where "alkyl" is C8-C20 aliphatic fatty acid residue, (CHR-CO-NH) is an amino acid radical forming a polypeptide by peptide linkages, n is 4 to 10 inclusive, R is hydrogen or alkyl and X is potassium, sodium, lithium or triethanolamine. The hygroscopic solvent may be propylene glycol, glycerine or polyoxyethylene glycol. Antibiotics, antiseptics, anaesthetics anti-inflammatory agents, astringents and anti-histaminics may also be included in the compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3832958A GB903256A (en) | 1958-11-27 | 1958-11-27 | Improvements in novel otologic preparations and the process for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3832958A GB903256A (en) | 1958-11-27 | 1958-11-27 | Improvements in novel otologic preparations and the process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB903256A true GB903256A (en) | 1962-08-15 |
Family
ID=10402761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3832958A Expired GB903256A (en) | 1958-11-27 | 1958-11-27 | Improvements in novel otologic preparations and the process for their preparation |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB903256A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7712005A (en) * | 1976-11-01 | 1978-05-03 | Procter & Gamble | METHOD OF PREPARING A PREPARATION FOR ACNE CONTROL. |
-
1958
- 1958-11-27 GB GB3832958A patent/GB903256A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7712005A (en) * | 1976-11-01 | 1978-05-03 | Procter & Gamble | METHOD OF PREPARING A PREPARATION FOR ACNE CONTROL. |
| FR2368949A1 (en) * | 1976-11-01 | 1978-05-26 | Procter & Gamble | ERYTHROMYCIN ANTIMICROBIAL PRODUCT FOR THE TOPICAL TREATMENT OF ACNE DISORDERS |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES482415A1 (en) | Process for making 4-aminohex-5-enoic acid | |
| GB813532A (en) | 4:4-dipyridyl compounds and compositions containing them | |
| SE7602966L (en) | DETERGENT COMPOSITION | |
| GB861560A (en) | N-substituted piperidines | |
| GB903256A (en) | Improvements in novel otologic preparations and the process for their preparation | |
| ES454086A1 (en) | Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -norosimorphone new. (Machine-translation by Google Translate, not legally binding) | |
| ES481573A1 (en) | Process for the preparation of the sodium salt of mercaptopropionylglycine | |
| ES451555A1 (en) | Shampoo composition | |
| GB772345A (en) | Improvements in or relating to preparation of polyvinylamine | |
| GB759877A (en) | Improvements in or relating to liquid detergent compositions | |
| GB1541185A (en) | 5-fluorouracil derivatives and their preparation | |
| GB794798A (en) | Pharmaceutical compositions | |
| AU225671B2 (en) | Improvements in turbojet engines as regards'reheat | |
| GB814866A (en) | Make-up removing compositions | |
| AU959555A (en) | Improvements in turbojet engines as regards'reheat | |
| GB799467A (en) | Compositions for providing protection against light | |
| ES255673A1 (en) | Procedure for the obtaining of new esters (Machine-translation by Google Translate, not legally binding) | |
| GB987796A (en) | Derivatives of n-acyl-2,4,6-triiodo-anilides and process for their preparation | |
| GB672691A (en) | Improvements in and relating to the preparation of sulphonic acid esters of bis-2-hydroxy-alkylarylamines | |
| GB709373A (en) | 6-methyl-8-hydroxy-ergoline | |
| GB757155A (en) | Novel haemostatic compositions | |
| GB995398A (en) | Novel hypotensive composition | |
| GB891004A (en) | Improvements in or relating to tetrocycline derivatives | |
| AU160897B2 (en) | Improvements relating to telephone exchange feeding' bridge circuits | |
| GB681905A (en) | Solutions of thiosemicarbazones |