FR2368949A1 - ERYTHROMYCIN ANTIMICROBIAL PRODUCT FOR THE TOPICAL TREATMENT OF ACNE DISORDERS - Google Patents
ERYTHROMYCIN ANTIMICROBIAL PRODUCT FOR THE TOPICAL TREATMENT OF ACNE DISORDERSInfo
- Publication number
- FR2368949A1 FR2368949A1 FR7732761A FR7732761A FR2368949A1 FR 2368949 A1 FR2368949 A1 FR 2368949A1 FR 7732761 A FR7732761 A FR 7732761A FR 7732761 A FR7732761 A FR 7732761A FR 2368949 A1 FR2368949 A1 FR 2368949A1
- Authority
- FR
- France
- Prior art keywords
- erythromycin
- topical treatment
- antimicrobial product
- acne
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 4
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 2
- 206010000496 acne Diseases 0.000 title abstract 2
- 230000000845 anti-microbial effect Effects 0.000 title abstract 2
- 229960003276 erythromycin Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 abstract 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- RZRNAYUHWVFMIP-HXUWFJFHSA-N glycerol monolinoleate Natural products CCCCCCCCC=CCCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-HXUWFJFHSA-N 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Produit antimicrobien destiné au traitement topique des affection acnéiques. Ce produit contient fondamentalement une quantité efficace d'érythromycine ou d'un composé ou dérivé de celle-ci et un support ou véhicule pharmaceutiquement acceptable, doué de propriétés particulières de pénétration dans la peau et contenant de 0 à environ 5 % de monooléate de glycérol, de 20 à 80 % environ d'éthanol, et le reste étant du myristate d'isopropyle, avec éventuellement des adjuvants tels que colorants, epaississants, ou autres. Traitement de toutes les lésions acnéiformes.Antimicrobial product for the topical treatment of acne conditions. This product basically contains an effective amount of erythromycin or a compound or derivative thereof and a pharmaceutically acceptable carrier or vehicle, endowed with particular skin penetrating properties and containing 0 to about 5% glycerol monooleate , from 20 to 80% approximately ethanol, and the remainder being isopropyl myristate, optionally with adjuvants such as dyes, thickeners, or others. Treatment of all acneiform lesions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73731576A | 1976-11-01 | 1976-11-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2368949A1 true FR2368949A1 (en) | 1978-05-26 |
| FR2368949B1 FR2368949B1 (en) | 1979-07-20 |
Family
ID=24963418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7732761A Granted FR2368949A1 (en) | 1976-11-01 | 1977-10-28 | ERYTHROMYCIN ANTIMICROBIAL PRODUCT FOR THE TOPICAL TREATMENT OF ACNE DISORDERS |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5394030A (en) |
| BE (1) | BE860349A (en) |
| CA (1) | CA1090253A (en) |
| DE (1) | DE2748399C2 (en) |
| FR (1) | FR2368949A1 (en) |
| GB (1) | GB1587428A (en) |
| IE (1) | IE45902B1 (en) |
| IT (1) | IT1088874B (en) |
| NL (1) | NL179185C (en) |
| PH (1) | PH15370A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027286A3 (en) * | 1979-10-12 | 1981-05-13 | The Procter & Gamble Company | Anti-acne composition and method |
| EP0091964A4 (en) * | 1981-09-28 | 1985-07-01 | Nitto Electric Ind Co | Base composition for preparing medicine for external application, medicinal composition for external application, and method for accelerating percutaneous absorption of medicinal agent. |
| EP0305026A3 (en) * | 1987-08-24 | 1990-02-14 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| RU2122396C1 (en) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Bioactive addition to cosmetics |
| RU2176511C1 (en) * | 2001-02-19 | 2001-12-10 | Закрытое акционерное общество "Коммерческий центр "НИЗАР" | Agent for prophylaxis of acne disease and method of its preparing |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2378523A1 (en) * | 1977-01-26 | 1978-08-25 | Grupper Charles | ACNE TREATMENT MEDICINE |
| IT1210608B (en) * | 1980-12-08 | 1989-09-14 | Rorer Int Overseas | COMPOSITION FOR TOPICAL ACNE TREATMENT |
| JPH0764754B2 (en) * | 1984-10-02 | 1995-07-12 | 花王株式会社 | Transdermal absorption enhancer and external preparation for skin containing the same |
| LU86393A1 (en) * | 1986-04-16 | 1987-12-07 | Oreal | STABLE ANTI-ACNE COMPOSITION BASED ON ERYTHROMYCIN |
| US5260292A (en) * | 1991-03-05 | 1993-11-09 | Marvin S. Towsend | Topical treatment of acne with aminopenicillins |
| DE4334553C2 (en) * | 1993-10-11 | 1998-05-20 | Synopharm Gmbh Pharmazeutische | Liquid pharmaceutical system for percutaneous application |
| WO2009013331A1 (en) * | 2007-07-25 | 2009-01-29 | Ixodes Gmbh | Topical antibiotic composition for the prevention of lyme disease |
| CA3211668A1 (en) * | 2021-03-16 | 2022-09-22 | Van Au | Cosmetic skin care composition |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914443A (en) * | 1958-03-31 | 1959-11-24 | Abbott Lab | Ointment |
| GB903256A (en) * | 1958-11-27 | 1962-08-15 | Mundipharma Ag | Improvements in novel otologic preparations and the process for their preparation |
| GB1048820A (en) * | 1963-05-29 | 1966-11-23 | Merck & Co Inc | Emollient compositions containing liquid fatty acid esters |
| FR2164802A1 (en) * | 1971-12-23 | 1973-08-03 | Merck & Co Inc | |
| DE2615140A1 (en) * | 1975-04-11 | 1976-10-21 | Nelson Res & Dev | VEHICULUM SYSTEM |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA945068A (en) * | 1967-10-25 | 1974-04-09 | Albert M. Kligman | Composition and method of treating acne |
-
1977
- 1977-10-28 FR FR7732761A patent/FR2368949A1/en active Granted
- 1977-10-28 DE DE2748399A patent/DE2748399C2/en not_active Expired
- 1977-10-28 CA CA289,778A patent/CA1090253A/en not_active Expired
- 1977-10-31 BE BE182239A patent/BE860349A/en not_active IP Right Cessation
- 1977-10-31 GB GB45189/77A patent/GB1587428A/en not_active Expired
- 1977-10-31 IT IT29235/77A patent/IT1088874B/en active
- 1977-11-01 IE IE2220/77A patent/IE45902B1/en not_active IP Right Cessation
- 1977-11-01 NL NLAANVRAGE7712005,A patent/NL179185C/en not_active IP Right Cessation
- 1977-11-01 JP JP13138377A patent/JPS5394030A/en active Pending
- 1977-11-08 PH PH20406A patent/PH15370A/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914443A (en) * | 1958-03-31 | 1959-11-24 | Abbott Lab | Ointment |
| GB903256A (en) * | 1958-11-27 | 1962-08-15 | Mundipharma Ag | Improvements in novel otologic preparations and the process for their preparation |
| GB1048820A (en) * | 1963-05-29 | 1966-11-23 | Merck & Co Inc | Emollient compositions containing liquid fatty acid esters |
| FR2164802A1 (en) * | 1971-12-23 | 1973-08-03 | Merck & Co Inc | |
| DE2615140A1 (en) * | 1975-04-11 | 1976-10-21 | Nelson Res & Dev | VEHICULUM SYSTEM |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027286A3 (en) * | 1979-10-12 | 1981-05-13 | The Procter & Gamble Company | Anti-acne composition and method |
| EP0091964A4 (en) * | 1981-09-28 | 1985-07-01 | Nitto Electric Ind Co | Base composition for preparing medicine for external application, medicinal composition for external application, and method for accelerating percutaneous absorption of medicinal agent. |
| EP0305026A3 (en) * | 1987-08-24 | 1990-02-14 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| RU2122396C1 (en) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Bioactive addition to cosmetics |
| RU2176511C1 (en) * | 2001-02-19 | 2001-12-10 | Закрытое акционерное общество "Коммерческий центр "НИЗАР" | Agent for prophylaxis of acne disease and method of its preparing |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7712005A (en) | 1978-05-03 |
| CA1090253A (en) | 1980-11-25 |
| IT1088874B (en) | 1985-06-10 |
| PH15370A (en) | 1982-12-10 |
| DE2748399A1 (en) | 1978-05-11 |
| FR2368949B1 (en) | 1979-07-20 |
| NL179185C (en) | 1986-08-01 |
| GB1587428A (en) | 1981-04-01 |
| DE2748399C2 (en) | 1983-09-15 |
| NL179185B (en) | 1986-03-03 |
| IE45902L (en) | 1978-05-01 |
| JPS5394030A (en) | 1978-08-17 |
| IE45902B1 (en) | 1982-12-29 |
| BE860349A (en) | 1978-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |