FR2368949A1 - Produit antimicrobien a base d'erythromycine pour le traitement topique des affections acneiques - Google Patents
Produit antimicrobien a base d'erythromycine pour le traitement topique des affections acneiquesInfo
- Publication number
- FR2368949A1 FR2368949A1 FR7732761A FR7732761A FR2368949A1 FR 2368949 A1 FR2368949 A1 FR 2368949A1 FR 7732761 A FR7732761 A FR 7732761A FR 7732761 A FR7732761 A FR 7732761A FR 2368949 A1 FR2368949 A1 FR 2368949A1
- Authority
- FR
- France
- Prior art keywords
- erythromycin
- topical treatment
- antimicrobial product
- acne
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 4
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 2
- 206010000496 acne Diseases 0.000 title abstract 2
- 230000000845 anti-microbial effect Effects 0.000 title abstract 2
- 229960003276 erythromycin Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 abstract 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- RZRNAYUHWVFMIP-HXUWFJFHSA-N glycerol monolinoleate Natural products CCCCCCCCC=CCCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-HXUWFJFHSA-N 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Produit antimicrobien destiné au traitement topique des affection acnéiques. Ce produit contient fondamentalement une quantité efficace d'érythromycine ou d'un composé ou dérivé de celle-ci et un support ou véhicule pharmaceutiquement acceptable, doué de propriétés particulières de pénétration dans la peau et contenant de 0 à environ 5 % de monooléate de glycérol, de 20 à 80 % environ d'éthanol, et le reste étant du myristate d'isopropyle, avec éventuellement des adjuvants tels que colorants, epaississants, ou autres. Traitement de toutes les lésions acnéiformes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73731576A | 1976-11-01 | 1976-11-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2368949A1 true FR2368949A1 (fr) | 1978-05-26 |
| FR2368949B1 FR2368949B1 (fr) | 1979-07-20 |
Family
ID=24963418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7732761A Granted FR2368949A1 (fr) | 1976-11-01 | 1977-10-28 | Produit antimicrobien a base d'erythromycine pour le traitement topique des affections acneiques |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5394030A (fr) |
| BE (1) | BE860349A (fr) |
| CA (1) | CA1090253A (fr) |
| DE (1) | DE2748399C2 (fr) |
| FR (1) | FR2368949A1 (fr) |
| GB (1) | GB1587428A (fr) |
| IE (1) | IE45902B1 (fr) |
| IT (1) | IT1088874B (fr) |
| NL (1) | NL179185C (fr) |
| PH (1) | PH15370A (fr) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027286A3 (en) * | 1979-10-12 | 1981-05-13 | The Procter & Gamble Company | Anti-acne composition and method |
| EP0091964A4 (fr) * | 1981-09-28 | 1985-07-01 | Nitto Electric Ind Co | Composition de base pour la preparation de medicaments pour une application externe, composition medicinale pour une application externe, et procede permettant d'accelerer l'absorption percutanee d'un agent medicinal. |
| EP0305026A3 (en) * | 1987-08-24 | 1990-02-14 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| RU2122396C1 (ru) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Биологически-активная добавка в косметические изделия |
| RU2176511C1 (ru) * | 2001-02-19 | 2001-12-10 | Закрытое акционерное общество "Коммерческий центр "НИЗАР" | Средство для профилактики угревой болезни и способ его получения |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2378523A1 (fr) * | 1977-01-26 | 1978-08-25 | Grupper Charles | Medicament pour le traitement de l'acne |
| IT1210608B (it) * | 1980-12-08 | 1989-09-14 | Rorer Int Overseas | Composizione per il trattamento topico dell'acne |
| JPH0764754B2 (ja) * | 1984-10-02 | 1995-07-12 | 花王株式会社 | 経皮吸収促進剤及びこれを含有する皮膚外用剤 |
| LU86393A1 (fr) * | 1986-04-16 | 1987-12-07 | Oreal | Composition anti-acneique stable a base d'erythromycine |
| US5260292A (en) * | 1991-03-05 | 1993-11-09 | Marvin S. Towsend | Topical treatment of acne with aminopenicillins |
| DE4334553C2 (de) * | 1993-10-11 | 1998-05-20 | Synopharm Gmbh Pharmazeutische | Flüssiges pharmazeutisches System zur perkutanen Applikation |
| WO2009013331A1 (fr) * | 2007-07-25 | 2009-01-29 | Ixodes Gmbh | Composition antibiotique topique pour la prévention de la maladie de lyme |
| CA3211668A1 (fr) * | 2021-03-16 | 2022-09-22 | Van Au | Composition cosmetique pour le soin de la peau |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914443A (en) * | 1958-03-31 | 1959-11-24 | Abbott Lab | Ointment |
| GB903256A (en) * | 1958-11-27 | 1962-08-15 | Mundipharma Ag | Improvements in novel otologic preparations and the process for their preparation |
| GB1048820A (en) * | 1963-05-29 | 1966-11-23 | Merck & Co Inc | Emollient compositions containing liquid fatty acid esters |
| FR2164802A1 (fr) * | 1971-12-23 | 1973-08-03 | Merck & Co Inc | |
| DE2615140A1 (de) * | 1975-04-11 | 1976-10-21 | Nelson Res & Dev | Vehiculumsystem |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA945068A (en) * | 1967-10-25 | 1974-04-09 | Albert M. Kligman | Composition and method of treating acne |
-
1977
- 1977-10-28 FR FR7732761A patent/FR2368949A1/fr active Granted
- 1977-10-28 DE DE2748399A patent/DE2748399C2/de not_active Expired
- 1977-10-28 CA CA289,778A patent/CA1090253A/fr not_active Expired
- 1977-10-31 BE BE182239A patent/BE860349A/fr not_active IP Right Cessation
- 1977-10-31 GB GB45189/77A patent/GB1587428A/en not_active Expired
- 1977-10-31 IT IT29235/77A patent/IT1088874B/it active
- 1977-11-01 IE IE2220/77A patent/IE45902B1/en not_active IP Right Cessation
- 1977-11-01 NL NLAANVRAGE7712005,A patent/NL179185C/xx not_active IP Right Cessation
- 1977-11-01 JP JP13138377A patent/JPS5394030A/ja active Pending
- 1977-11-08 PH PH20406A patent/PH15370A/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914443A (en) * | 1958-03-31 | 1959-11-24 | Abbott Lab | Ointment |
| GB903256A (en) * | 1958-11-27 | 1962-08-15 | Mundipharma Ag | Improvements in novel otologic preparations and the process for their preparation |
| GB1048820A (en) * | 1963-05-29 | 1966-11-23 | Merck & Co Inc | Emollient compositions containing liquid fatty acid esters |
| FR2164802A1 (fr) * | 1971-12-23 | 1973-08-03 | Merck & Co Inc | |
| DE2615140A1 (de) * | 1975-04-11 | 1976-10-21 | Nelson Res & Dev | Vehiculumsystem |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027286A3 (en) * | 1979-10-12 | 1981-05-13 | The Procter & Gamble Company | Anti-acne composition and method |
| EP0091964A4 (fr) * | 1981-09-28 | 1985-07-01 | Nitto Electric Ind Co | Composition de base pour la preparation de medicaments pour une application externe, composition medicinale pour une application externe, et procede permettant d'accelerer l'absorption percutanee d'un agent medicinal. |
| EP0305026A3 (en) * | 1987-08-24 | 1990-02-14 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| RU2122396C1 (ru) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Биологически-активная добавка в косметические изделия |
| RU2176511C1 (ru) * | 2001-02-19 | 2001-12-10 | Закрытое акционерное общество "Коммерческий центр "НИЗАР" | Средство для профилактики угревой болезни и способ его получения |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7712005A (nl) | 1978-05-03 |
| CA1090253A (fr) | 1980-11-25 |
| IT1088874B (it) | 1985-06-10 |
| PH15370A (en) | 1982-12-10 |
| DE2748399A1 (de) | 1978-05-11 |
| FR2368949B1 (fr) | 1979-07-20 |
| NL179185C (nl) | 1986-08-01 |
| GB1587428A (en) | 1981-04-01 |
| DE2748399C2 (de) | 1983-09-15 |
| NL179185B (nl) | 1986-03-03 |
| IE45902L (en) | 1978-05-01 |
| JPS5394030A (en) | 1978-08-17 |
| IE45902B1 (en) | 1982-12-29 |
| BE860349A (fr) | 1978-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |