FR2235687A2 - 1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc. - Google Patents
1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc.Info
- Publication number
- FR2235687A2 FR2235687A2 FR7324387A FR7324387A FR2235687A2 FR 2235687 A2 FR2235687 A2 FR 2235687A2 FR 7324387 A FR7324387 A FR 7324387A FR 7324387 A FR7324387 A FR 7324387A FR 2235687 A2 FR2235687 A2 FR 2235687A2
- Authority
- FR
- France
- Prior art keywords
- carboxamido
- indoles
- hypotensives
- anticholinergics
- inflammatories
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- 239000000932 sedative agent Substances 0.000 title abstract 2
- 208000001953 Hypotension Diseases 0.000 title 1
- 229940035676 analgesics Drugs 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 title 1
- 239000003699 antiulcer agent Substances 0.000 title 1
- 239000000812 cholinergic antagonist Substances 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 229940125723 sedative agent Drugs 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 title 1
- 239000003071 vasodilator agent Substances 0.000 title 1
- -1 Carboxamido indoles Chemical class 0.000 abstract 7
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 230000002517 constrictor effect Effects 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Carboxamido indoles of formula (I): (where R is straight or branched 1-4C alkylamino, pyrrolidino, piperidino, morpholino, hexamethyleneimino or piperazino substd. in the 4-posn. by a pyrrolidino carbonylmethyl, isopropylamino carbonylmethyl, morpholino carbonylmethyl or ethoxycarbonylmethyl gp.). have antiulcerous, antibroncho-constrictive, anticholinergic, analgesic, anti-inflammatory, sedative, diuretic, vasodilative and hypotensive activity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7324387A FR2235687A2 (en) | 1973-07-03 | 1973-07-03 | 1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7324387A FR2235687A2 (en) | 1973-07-03 | 1973-07-03 | 1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2235687A2 true FR2235687A2 (en) | 1975-01-31 |
| FR2235687B2 FR2235687B2 (en) | 1977-08-19 |
Family
ID=9121983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7324387A Granted FR2235687A2 (en) | 1973-07-03 | 1973-07-03 | 1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc. |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2235687A2 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3466287A (en) * | 1966-10-07 | 1969-09-09 | Sterling Drug Inc | 1-((3-indolyl)-lower-alkyl)-4-substituted piperazines |
| GB1273563A (en) * | 1968-07-24 | 1972-05-10 | Wyeth John & Brother Ltd | Indoles |
-
1973
- 1973-07-03 FR FR7324387A patent/FR2235687A2/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3466287A (en) * | 1966-10-07 | 1969-09-09 | Sterling Drug Inc | 1-((3-indolyl)-lower-alkyl)-4-substituted piperazines |
| GB1273563A (en) * | 1968-07-24 | 1972-05-10 | Wyeth John & Brother Ltd | Indoles |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2235687B2 (en) | 1977-08-19 |
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