FI943146L - Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen - Google Patents

Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen Download PDF

Info

Publication number: FI943146L
Authority: FI; Finland
Prior art keywords: staphylokinases; expression; free; signal peptides; peptides
Prior art date: 1991-12-30

Application number

FI943146A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI943146A0 (fi

FI943146A7 (fi

Inventor

Detlev Behnke

Bernhard Schlott

Sybille Albrecht

Karl-Heinz Guehrs

Manfred Hartmann

Original Assignee

Medac Klinische Spezialpraep

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-30

Filing date

1992-12-28

Publication date

1994-06-30

1991-12-30 Priority claimed from DE4143279A external-priority patent/DE4143279A1/de

1992-12-01 Priority claimed from DE4240801A external-priority patent/DE4240801A1/de

1992-12-28 Application filed by Medac Klinische Spezialpraep filed Critical Medac Klinische Spezialpraep

1994-06-30 Publication of FI943146A0 publication Critical patent/FI943146A0/fi

1994-06-30 Publication of FI943146A7 publication Critical patent/FI943146A7/fi

1994-06-30 Publication of FI943146L publication Critical patent/FI943146L/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Immunology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI943146A 1991-12-30 1992-12-28 Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen FI943146L (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE4143279A DE4143279A1 (de)	1991-12-30	1991-12-30	Neue plasminogenaktivatoren, die sie kodierenden dna-sequenzen, zugehoerige expressionsplasmide und rekombinante escherichia coli-staemme, verfahren zur produktion dieser proteine und ihre verwendung
DE4220516		1992-06-22
DE4240801A DE4240801A1 (de)	1992-12-01	1992-12-01	Reife methioninfreie Staphylokinasen, die sie kodierenden DNA-Sequenzen, zugehörige Expressionsplasmide und rekombinante Escherichia coli-Stämme, Verfahren zur Herstellung dieser Proteine und ihre Verwendung
PCT/EP1992/002989 WO1993013209A1 (fr)	1991-12-30	1992-12-28	Staphilokinases exemptes de peptides-signal d'expression

Publications (3)

Publication Number	Publication Date
FI943146A0 FI943146A0 (fi)	1994-06-30
FI943146A7 FI943146A7 (fi)	1994-06-30
FI943146L true FI943146L (fi)	1994-06-30

Family

ID=27203268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI943146A FI943146L (fi)	1991-12-30	1992-12-28	Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen

Country Status (14)

Country	Link
US (2)	US5801037A (fr)
EP (1)	EP0621899B1 (fr)
JP (1)	JP3310672B2 (fr)
KR (1)	KR100221150B1 (fr)
AT (1)	ATE139570T1 (fr)
AU (1)	AU669149B2 (fr)
DE (1)	DE59206628D1 (fr)
DK (1)	DK0621899T3 (fr)
ES (1)	ES2089784T3 (fr)
FI (1)	FI943146L (fr)
GR (1)	GR3020529T3 (fr)
HK (1)	HK1005886A1 (fr)
HU (1)	HU218043B (fr)
WO (1)	WO1993013209A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU669149B2 (en) *	1991-12-30	1996-05-30	Thromb-X N.V.	Expression signal-peptide-free staphylokinases
CN1035192C (zh) *	1994-04-04	1997-06-18	上海医科大学	一种重组葡激酶的制备方法
EP0721982A1 (fr) *	1995-01-06	1996-07-17	Leuven Research & Development V.Z.W.	Des dérivés nouveaux de la staphylokinase
ATE290598T1 (de) *	1995-01-06	2005-03-15	Leuven Res & Dev Vzw	Neue staphylokinase derivate
JP3399963B2 (ja)	1995-01-06	2003-04-28	リューベン・リサーチ・アンド・デベロップメント・ベー・ゼット・ウェー	新規スタフィロキナーゼ誘導体
JPH08289790A (ja) *	1995-01-06	1996-11-05	Leuven Res & Dev Vzw	新規なスタフィロキナーゼ誘導体
US5846943A (en) *	1996-11-08	1998-12-08	Synsorb Biotech, Inc.	Solid support matricles containing a toxin binding oligosaccharide
CN1059926C (zh) *	1997-07-19	2000-12-27	张其玖	葡激酶基因及其高表达工程菌株
JP2002505082A (ja) *	1998-02-04	2002-02-19	トロンブ−イックス・ナムローゼ・フェンノートシャップ	減少した免疫原性および／または減少したクリアランスを有するスタフィロキナーゼ誘導体の同定、製造および使用方法
US7781209B2 (en) *	2005-09-25	2010-08-24	Multispan, Inc.	GPCR-expressing cell lines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5867181A (ja) *	1981-10-16	1983-04-21	Yakult Honsha Co Ltd	スタフイロキナーゼ産生遺伝情報を担うｄｎａ断片組み換え体ｄｎａおよびそれを導入した大腸菌
WO1987002732A1 (fr) *	1985-11-01	1987-05-07	Vaughan Thomas L	Assemblage de suspension d'un materiel medical ou autre
ATE158613T1 (de) *	1990-12-17	1997-10-15	Yakult Honsha Kk	Thrombolytisches peptid, seine produktion und thrombolisches agens
ES2096617T3 (es) *	1991-06-28	1997-03-16	Leuven Res & Dev Vzw	Uso de estafiloquinasa para la preparacion de una composicion farmaceutica para tratar trombosis arterial.
AU669149B2 (en) *	1991-12-30	1996-05-30	Thromb-X N.V.	Expression signal-peptide-free staphylokinases

1992
- 1992-12-28 AU AU33472/93A patent/AU669149B2/en not_active Expired
- 1992-12-28 WO PCT/EP1992/002989 patent/WO1993013209A1/fr not_active Ceased
- 1992-12-28 ES ES93902129T patent/ES2089784T3/es not_active Expired - Lifetime
- 1992-12-28 JP JP51143493A patent/JP3310672B2/ja not_active Expired - Lifetime
- 1992-12-28 DK DK93902129.1T patent/DK0621899T3/da active
- 1992-12-28 AT AT93902129T patent/ATE139570T1/de not_active IP Right Cessation
- 1992-12-28 FI FI943146A patent/FI943146L/fi not_active Application Discontinuation
- 1992-12-28 DE DE59206628T patent/DE59206628D1/de not_active Expired - Lifetime
- 1992-12-28 EP EP93902129A patent/EP0621899B1/fr not_active Expired - Lifetime
- 1992-12-28 US US08/256,261 patent/US5801037A/en not_active Expired - Lifetime
- 1992-12-28 KR KR1019940702287A patent/KR100221150B1/ko not_active Expired - Lifetime
- 1992-12-28 HU HU9401949A patent/HU218043B/hu not_active IP Right Cessation
1996
- 1996-07-12 GR GR960401892T patent/GR3020529T3/el unknown
1997
- 1997-05-17 US US08/852,299 patent/US6010897A/en not_active Expired - Lifetime
1998
- 1998-06-05 HK HK98104968A patent/HK1005886A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR100221150B1 (ko)	1999-10-01
AU3347293A (en)	1993-07-28
HK1005886A1 (en)	1999-01-29
HU9401949D0 (en)	1994-11-28
US6010897A (en)	2000-01-04
ATE139570T1 (de)	1996-07-15
EP0621899B1 (fr)	1996-06-19
AU669149B2 (en)	1996-05-30
KR940703920A (ko)	1994-12-12
GR3020529T3 (en)	1996-10-31
US5801037A (en)	1998-09-01
HUT68067A (en)	1995-05-29
DE59206628D1 (en)	1996-07-25
FI943146A0 (fi)	1994-06-30
FI943146A7 (fi)	1994-06-30
JP3310672B2 (ja)	2002-08-05
HU218043B (hu)	2000-05-28
EP0621899A1 (fr)	1994-11-02
WO1993013209A1 (fr)	1993-07-08
ES2089784T3 (es)	1996-10-01
DK0621899T3 (da)	1996-10-28
JPH07502652A (ja)	1995-03-23

Publication	Publication Date	Title
ATE190066T1 (de)	2000-03-15	Neuartige peptidderivate
FI933084L (fi)	1994-01-09	Signalanordning
FI941398L (fi)	1994-03-25	Modifioituja peptidijohdannaisia
DE69120679D1 (de)	1996-08-08	Signalkodierung
DE69232476D1 (de)	2002-04-18	Feststellung von Fehlern
DE69030128D1 (de)	1997-04-17	Signalprozessor
DE69213271D1 (de)	1996-10-10	Kodierung von Videosignalen
DE69230064D1 (de)	1999-11-04	Signalprozessor
DE69220382D1 (de)	1997-07-17	Verwendung von Peptidderivaten
FI923119A7 (fi)	1993-01-12	Krutdriven montageanordning med magasin foer faestelement
DE69222082D1 (de)	1997-10-16	Kodierung von Videosignalen
FI941758L (fi)	1994-06-16	Rekombitooppipeptidejä
FI914947A7 (fi)	1991-10-21	Polypeptidien parantunut ilmentyminen
DE69430093D1 (de)	2002-04-18	Signalprozessor
DE69318866D1 (de)	1998-07-09	Signalverarbeitungsanordnungen
FI933814L (fi)	1993-09-01	Framstaellning av faktor-ix
FI943146L (fi)	1994-06-30	Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen
DE68927704D1 (de)	1997-03-06	Signalprozessor
FI941749L (fi)	1994-05-25	Rekombinantti-Borrelia -proteiinien valmistus
DE69418754D1 (de)	1999-07-08	Signalprozessor
FI923311A7 (fi)	1993-01-25	Proteiineja
FI915661L (fi)	1993-05-30	En deviationsbegraensare foer en fraon en radiotelefon utsaend signal
DE69127991D1 (de)	1997-11-27	Signalprozessor
DE69416372D1 (de)	1999-03-18	Signalprozessor
FI913183L (fi)	1992-12-29	Foerfarande foer bildning av en signal

Legal Events

Date	Code	Title	Description
1997-12-04	GB	Transfer or assigment of application	Owner name: THROMB-X N.V.
2005-04-21	FD	Application lapsed