ES461020A1 - Organic compounds - Google Patents
Organic compoundsInfo
- Publication number
- ES461020A1 ES461020A1 ES461020A ES461020A ES461020A1 ES 461020 A1 ES461020 A1 ES 461020A1 ES 461020 A ES461020 A ES 461020A ES 461020 A ES461020 A ES 461020A ES 461020 A1 ES461020 A1 ES 461020A1
- Authority
- ES
- Spain
- Prior art keywords
- drug core
- group
- coated
- drug
- gastric juices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002894 organic compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 210000004051 gastric juice Anatomy 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003945 anionic surfactant Substances 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 150000002191 fatty alcohols Chemical class 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento para la preparación de composiciones para la liberación controlada de agentes cardiacos y circulatorios, en el conducto intestinal, caracterizado porque se mezcla (a) un agente farmacológicamente activo seleccionado del grupo de arilalcanolaminas y ariloxialcanolaminas, y (b) un agente tensioactivo aniónico fisiológicamente tolerable seleccionado del grupo de ésteres de ácido mono-sulfúrico de alcoholes grasos superiores, porque se produce facultativamente un núcleo de medicamento a partir de la misma, se reviste el núcleo de medicamento con una película que es resistente a los jugos gástricos pero que se descompone a un ph superior a 5, y porque se aplica facultativamente sobre el núcleo de medicamento revestido una capa de medicamento que se disuelve en los jugos gástricos.Procedure for the preparation of compositions for the controlled release of cardiac and circulatory agents, in the intestinal tract, characterized in that (a) a pharmacologically active agent selected from the group of arylalkanolamines and aryloxyalkanolamines is mixed, and (b) a physiologically tolerable anionic surfactant selected from the group of mono-sulfuric acid esters of higher fatty alcohols, because a drug core is optionally produced therefrom, the drug core is coated with a film that is resistant to gastric juices but decomposes under a pH greater than 5, and because a layer of drug that dissolves in gastric juices is optionally applied to the coated drug core.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH958876 | 1976-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES461020A1 true ES461020A1 (en) | 1979-05-01 |
Family
ID=4353539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461020A Expired ES461020A1 (en) | 1976-07-27 | 1977-07-26 | Organic compounds |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS5315411A (en) |
| AR (1) | AR216479A1 (en) |
| AT (1) | AT369987B (en) |
| AU (1) | AU515738B2 (en) |
| BE (1) | BE857122A (en) |
| CA (1) | CA1095833A (en) |
| CY (1) | CY1261A (en) |
| DE (1) | DE2732335C2 (en) |
| DK (1) | DK325677A (en) |
| ES (1) | ES461020A1 (en) |
| FI (1) | FI772217A7 (en) |
| FR (1) | FR2359607A1 (en) |
| GB (1) | GB1589982A (en) |
| GR (1) | GR65014B (en) |
| HK (1) | HK81884A (en) |
| HU (1) | HU178340B (en) |
| IE (1) | IE45534B1 (en) |
| IL (1) | IL52587A (en) |
| KE (1) | KE3441A (en) |
| MY (1) | MY8400057A (en) |
| NL (1) | NL176227C (en) |
| NO (1) | NO149874C (en) |
| NZ (1) | NZ184722A (en) |
| PT (1) | PT66850B (en) |
| SE (1) | SE437469B (en) |
| SG (1) | SG53884G (en) |
| ZA (1) | ZA774536B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH649216A5 (en) * | 1979-08-16 | 1985-05-15 | Sandoz Ag | METHOD FOR APPLYING AN ACID-RESISTANT FILM TO A MEDICINAL CORE AND SOLID UNIT DOSAGE FORM WITH ACID-ACID RESISTANT FILM. |
| FR2471186A1 (en) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | NEW COLIC DELITESCENCE TABLETS AND THEIR PREPARATION PROCESS |
| JPS6056122B2 (en) * | 1980-05-21 | 1985-12-09 | 塩野義製薬株式会社 | sustained release formulation |
| JPS5748908A (en) * | 1980-09-08 | 1982-03-20 | Kyorin Pharmaceut Co Ltd | Prolonged release type nicomol pharmaceutical |
| US4795327A (en) * | 1984-03-26 | 1989-01-03 | Forest Laboratories, Inc. | Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants |
| US4540566A (en) * | 1984-04-02 | 1985-09-10 | Forest Laboratories, Inc. | Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose |
| JPS61254522A (en) * | 1985-05-02 | 1986-11-12 | Takada Seiyaku Kk | Tablet composition |
| JPS62246512A (en) * | 1986-04-18 | 1987-10-27 | Fujisawa Pharmaceut Co Ltd | Drug preparation having repeating action |
| GB9714675D0 (en) * | 1997-07-11 | 1997-09-17 | Smithkline Beecham Plc | Novel composition |
| DE19959419A1 (en) | 1999-12-09 | 2001-06-21 | Ratiopharm Gmbh | Stable pharmaceutical preparations comprising a benzimidazole and process for their preparation |
| US20030113366A1 (en) * | 2001-12-14 | 2003-06-19 | Macgregor Alexander | Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3148124A (en) * | 1962-06-12 | 1964-09-08 | William E Gaunt | Method of preparing sustained release pharmaceutical tablets |
| CA927282A (en) * | 1968-09-03 | 1973-05-29 | S. Banker Gilbert | Entrapment compositions and processes |
| GB1301849A (en) * | 1969-12-15 | 1973-01-04 | ||
| US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
-
1977
- 1977-07-16 DE DE2732335A patent/DE2732335C2/en not_active Expired
- 1977-07-18 SE SE7708265A patent/SE437469B/en unknown
- 1977-07-18 FI FI772217A patent/FI772217A7/fi not_active Application Discontinuation
- 1977-07-18 DK DK325677A patent/DK325677A/en not_active Application Discontinuation
- 1977-07-19 NO NO772575A patent/NO149874C/en unknown
- 1977-07-22 CY CY1261A patent/CY1261A/en unknown
- 1977-07-22 GB GB30856/77A patent/GB1589982A/en not_active Expired
- 1977-07-22 NL NLAANVRAGE7708162,A patent/NL176227C/en not_active IP Right Cessation
- 1977-07-25 HU HU77SA3050A patent/HU178340B/en unknown
- 1977-07-25 IE IE1541/77A patent/IE45534B1/en not_active IP Right Cessation
- 1977-07-25 GR GR54032A patent/GR65014B/en unknown
- 1977-07-25 BE BE179609A patent/BE857122A/en not_active IP Right Cessation
- 1977-07-25 IL IL52587A patent/IL52587A/en not_active IP Right Cessation
- 1977-07-25 NZ NZ184722A patent/NZ184722A/en unknown
- 1977-07-25 CA CA283,403A patent/CA1095833A/en not_active Expired
- 1977-07-25 AU AU27301/77A patent/AU515738B2/en not_active Expired
- 1977-07-26 AT AT0541377A patent/AT369987B/en not_active IP Right Cessation
- 1977-07-26 JP JP8887677A patent/JPS5315411A/en active Granted
- 1977-07-26 ES ES461020A patent/ES461020A1/en not_active Expired
- 1977-07-26 PT PT66850A patent/PT66850B/en unknown
- 1977-07-27 ZA ZA00774536A patent/ZA774536B/en unknown
- 1977-07-27 FR FR7723022A patent/FR2359607A1/en active Granted
- 1977-07-27 AR AR268575A patent/AR216479A1/en active
-
1984
- 1984-08-03 SG SG538/84A patent/SG53884G/en unknown
- 1984-08-22 KE KE3441A patent/KE3441A/en unknown
- 1984-11-25 HK HK818/84A patent/HK81884A/en unknown
- 1984-12-30 MY MY57/84A patent/MY8400057A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990601 |