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ES2119818T3 - Preparacion oral para liberacion en el tracto digestivo inferior. - Google Patents

Preparacion oral para liberacion en el tracto digestivo inferior.

Info

Publication number
ES2119818T3
ES2119818T3 ES92917820T ES92917820T ES2119818T3 ES 2119818 T3 ES2119818 T3 ES 2119818T3 ES 92917820 T ES92917820 T ES 92917820T ES 92917820 T ES92917820 T ES 92917820T ES 2119818 T3 ES2119818 T3 ES 2119818T3
Authority
ES
Spain
Prior art keywords
release
digestive tract
oral preparation
lower digestive
quitosan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92917820T
Other languages
English (en)
Inventor
Akiya Yamada
Takahiko Wato
Naoki Uchida
Misuzu Fujisawa
Shigeyuki Takama
Yukiko Inamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Seiyaku Co Ltd
Original Assignee
Teikoku Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Co Ltd filed Critical Teikoku Seiyaku Co Ltd
Application granted granted Critical
Publication of ES2119818T3 publication Critical patent/ES2119818T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE PRESENTA UNA PREPARACION ORAL PARA SU LIBERACION EN EL TRACTO DIGESTIVO INFERIOR, QUE SE PREPARA LLENANDO UNA CAPSULA DURA HECHA DE UNA BASE QUE PRINCIPALMENTE COMPRENDA QUITOSAN CON UNA PREPARACION SOLIDA QUE CONTENGA UN AGENTE PRINCIPAL Y UN ACIDO ORGANICO SOLIDO QUE, EN UN ESTADO DISUELTO, PUEDA DISOLVER EL QUITOSAN Y FORMAR UN RECUBRIMIENTO ENTERICO SOBRE LA SUPERFICIE DE LA CAPSULA. LA PREPARACION HACE POSIBLE EL AJUSTE DE CUALQUIER TIEMPO DE LIBERACION DESEADO SIN QUE SEA AFECTADO CON EL PH EN VIRTUD DE LA PERMEABILIDAD AL AGUA DEBIDA A LA POROSIDAD DEL QUITOSAN.
ES92917820T 1992-08-13 1992-08-13 Preparacion oral para liberacion en el tracto digestivo inferior. Expired - Lifetime ES2119818T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1992/001037 WO1994004135A1 (fr) 1992-08-13 1992-08-13 Preparation administree par voie orale et destinee a etre liberee dans le tube digestif inferieur

Publications (1)

Publication Number Publication Date
ES2119818T3 true ES2119818T3 (es) 1998-10-16

Family

ID=14042489

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92917820T Expired - Lifetime ES2119818T3 (es) 1992-08-13 1992-08-13 Preparacion oral para liberacion en el tracto digestivo inferior.

Country Status (8)

Country Link
US (1) US5468503A (es)
EP (1) EP0616802B1 (es)
AU (1) AU657573B2 (es)
CA (1) CA2121038C (es)
DE (1) DE69225979T2 (es)
DK (1) DK0616802T3 (es)
ES (1) ES2119818T3 (es)
WO (1) WO1994004135A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427667A1 (de) * 1994-08-04 1996-02-15 Bremer Sonderabfall Beratungsg Biologisch abbaubarer Werkstoff, Verfahren zu dessen Herstellung sowie Verwendung desselben
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
IE75744B1 (en) * 1995-04-03 1997-09-24 Elan Corp Plc Controlled release biodegradable micro- and nanospheres containing cyclosporin
SG80553A1 (en) 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
NL1006774C2 (nl) 1996-08-14 1998-09-28 Univ Potchefstroom Anti-atherosclerose- en anti-trombotisch middel en het gebruik daarvan.
JP2000290187A (ja) * 1999-04-05 2000-10-17 Toshio Sato キトサン入りソフトカプセル及びその製造方法
DE59908471D1 (de) 1999-07-02 2004-03-11 Cognis Iberia Sl Mikrokapseln - II
ES2247749T3 (es) 1999-07-02 2006-03-01 Cognis Ip Management Gmbh Microcapsulas iii.
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1248841B1 (en) 2000-01-10 2008-07-23 Novartis Vaccines and Diagnostics, Inc. Genes differentially expressed in breast cancer
FI20011403L (fi) * 2001-06-29 2002-12-30 Carbion Oy Menetelmä ja koostumukset vatsan sairauksien hoitoon
US20030199457A1 (en) * 2002-04-17 2003-10-23 El-Naggar Mawaheb M. Prevention and treatment of thromboembolic disorders associated with arterial & venous thrombosis
GB0310919D0 (en) * 2003-05-13 2003-06-18 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
KR101007865B1 (ko) * 2007-06-18 2011-01-14 연세대학교 산학협력단 키토산 및 피틴산을 포함하는 서방성 키토산 캡슐
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
EP2753310B1 (de) 2011-09-07 2021-03-24 Roland Saur-Brosch Formulierung zur kontrollierten freisetzung eines oder mehreren stoffe im verdauungstrakt eines säugetiers
JP5102401B1 (ja) * 2012-03-30 2012-12-19 森下仁丹株式会社 大腸特異崩壊性カプセル
CN113350314B (zh) * 2021-06-25 2022-07-26 上海信谊天平药业有限公司 一种缓释药物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895724A (en) * 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
JPH03255037A (ja) * 1990-03-02 1991-11-13 Santen Pharmaceut Co Ltd グリチルリチン製剤
JPH064531B2 (ja) * 1990-06-04 1994-01-19 アイセロ化学株式会社 大腸崩壊性硬質カプセル
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
JP3122478B2 (ja) * 1991-02-19 2001-01-09 帝國製薬株式会社 下部消化管放出型経口製剤

Also Published As

Publication number Publication date
EP0616802B1 (en) 1998-06-17
DE69225979D1 (de) 1998-07-23
EP0616802A4 (en) 1996-06-12
AU657573B2 (en) 1995-03-16
CA2121038A1 (en) 1994-03-03
DK0616802T3 (da) 1998-10-19
DE69225979T2 (de) 1998-12-17
EP0616802A1 (en) 1994-09-28
CA2121038C (en) 2002-05-14
WO1994004135A1 (fr) 1994-03-03
AU2429692A (en) 1994-03-15
US5468503A (en) 1995-11-21

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Effective date: 19951117

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