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ES2115424T3 - Derivados prolin-amidicos basicos de los antibioticos ge 2270 y similares a ge 2270. - Google Patents

Derivados prolin-amidicos basicos de los antibioticos ge 2270 y similares a ge 2270.

Info

Publication number
ES2115424T3
ES2115424T3 ES96903955T ES96903955T ES2115424T3 ES 2115424 T3 ES2115424 T3 ES 2115424T3 ES 96903955 T ES96903955 T ES 96903955T ES 96903955 T ES96903955 T ES 96903955T ES 2115424 T3 ES2115424 T3 ES 2115424T3
Authority
ES
Spain
Prior art keywords
antibiotics
similar
amidic derivatives
basic
amidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96903955T
Other languages
English (en)
Inventor
Sergio Lociuro
Pierfausto Seneci
Ermenegildo Restelli
Romeo Ciabatti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosearch Italia SpA
Original Assignee
Biosearch Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosearch Italia SpA filed Critical Biosearch Italia SpA
Application granted granted Critical
Publication of ES2115424T3 publication Critical patent/ES2115424T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS BASICOS AMIDICOS DE ANTIBIOTICOS GE 2270 Y SIMILARES A GE 2270 DE FORMULA GENERAL (I), DONDE EL GRUPO GE REPRESENTA LA MOLECULA NUCLEO DEL ANTIBIOTICO. LOS DERIVADOS AMIDICOS DEL ANTIBIOTICO GE 2270 DE FORMULA (I) SON AGENTES ANTIMICROBIANOS PRINCIPALMENTE ACTIVOS FRENTE A BACTERIAS GRAM POSITIVAS.
ES96903955T 1995-02-07 1996-02-01 Derivados prolin-amidicos basicos de los antibioticos ge 2270 y similares a ge 2270. Expired - Lifetime ES2115424T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95101597 1995-02-07

Publications (1)

Publication Number Publication Date
ES2115424T3 true ES2115424T3 (es) 1998-06-16

Family

ID=8218961

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96903955T Expired - Lifetime ES2115424T3 (es) 1995-02-07 1996-02-01 Derivados prolin-amidicos basicos de los antibioticos ge 2270 y similares a ge 2270.

Country Status (12)

Country Link
US (1) US6143739A (es)
EP (1) EP0801655B1 (es)
JP (1) JP2825667B2 (es)
KR (1) KR100381688B1 (es)
AT (1) ATE165101T1 (es)
AU (1) AU693995B2 (es)
CA (1) CA2212372A1 (es)
DE (1) DE69600244T2 (es)
DK (1) DK0801655T3 (es)
ES (1) ES2115424T3 (es)
SI (1) SI0801655T1 (es)
WO (1) WO1996024607A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891869A (en) * 1995-02-07 1999-04-06 Biosearch Italia, S.P.A. Basic oxazoline-amide derivatives of GE2270 and GE2270-like antibiotics
CA2212372A1 (en) * 1995-02-07 1996-08-15 Biosearch Italia S.P.A. Basic proline-amide derivatives of ge 2270 and ge 2270-like antibiotics
US6008225A (en) * 1996-02-14 1999-12-28 Biosearch Italia, S.P.A. Derivatives of antibiotic GE2270 factors C2a, D2 and E
EP1180513A4 (en) * 1999-04-28 2002-07-10 Takeda Chemical Industries Ltd Cyclic amide compounds, process for the preparation of the same and uses thereof
EP1553967B1 (en) * 2002-06-17 2011-05-18 NAICONS s.c.a.r.l. Use of amide derivative of ge 2270 factor a3 for the treatment of acne
HUE041133T2 (hu) * 2002-11-18 2019-05-28 Vicuron Pharmaceuticals Llc Dalbavancin adagolási módszer bakteriális fertõzések kezelésére
US7119061B2 (en) * 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US8288606B2 (en) * 2005-03-08 2012-10-16 Ineos Usa Llc Propylene polymer catalyst donor component
AR060977A1 (es) * 2006-05-31 2008-07-23 Novartis Ag Aminotiazoles y sus usos
EP2097423B1 (en) * 2006-12-20 2011-03-02 Novartis AG Aminothiazole macrocycles, their use as antibacterial compounds and processes for their production
CA2708793C (en) 2007-12-12 2016-06-21 Novartis Ag Aminothiazoles and their uses

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202241A (en) * 1988-09-09 1993-04-13 Gruppo Lepetit S.P.A. Antibiotic GE 2270
DE69016284T2 (de) * 1989-07-04 1995-05-24 Lepetit Spa Antibiotikum GE 22270, Faktoren A1,A2,A3 und H.
ES2071143T3 (es) * 1990-03-08 1995-06-16 Lepetit Spa Factores b1, b2, c1, c2, d1, d2, e y t del antibiotico ge 2270.
IL100572A (en) * 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
ATE163428T1 (de) * 1991-08-30 1998-03-15 Biosearch Italia Spa Faktor c2a des antibiotikums ce 2270
US5891869A (en) * 1995-02-07 1999-04-06 Biosearch Italia, S.P.A. Basic oxazoline-amide derivatives of GE2270 and GE2270-like antibiotics
CA2212372A1 (en) * 1995-02-07 1996-08-15 Biosearch Italia S.P.A. Basic proline-amide derivatives of ge 2270 and ge 2270-like antibiotics
US6008225A (en) * 1996-02-14 1999-12-28 Biosearch Italia, S.P.A. Derivatives of antibiotic GE2270 factors C2a, D2 and E

Also Published As

Publication number Publication date
DE69600244D1 (de) 1998-05-20
SI0801655T1 (en) 1998-08-31
ATE165101T1 (de) 1998-05-15
JP2825667B2 (ja) 1998-11-18
CA2212372A1 (en) 1996-08-15
DE69600244T2 (de) 1998-10-01
KR19980701996A (ko) 1998-06-25
WO1996024607A1 (en) 1996-08-15
AU4785896A (en) 1996-08-27
EP0801655A1 (en) 1997-10-22
AU693995B2 (en) 1998-07-09
JPH10504040A (ja) 1998-04-14
US6143739A (en) 2000-11-07
KR100381688B1 (ko) 2003-12-11
DK0801655T3 (da) 1999-02-08
EP0801655B1 (en) 1998-04-15

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