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ES2067325T3 - Amidas de factores del antibiotico ge 2270. - Google Patents

Amidas de factores del antibiotico ge 2270.

Info

Publication number
ES2067325T3
ES2067325T3 ES92901892T ES92901892T ES2067325T3 ES 2067325 T3 ES2067325 T3 ES 2067325T3 ES 92901892 T ES92901892 T ES 92901892T ES 92901892 T ES92901892 T ES 92901892T ES 2067325 T3 ES2067325 T3 ES 2067325T3
Authority
ES
Spain
Prior art keywords
antibiotic
amides
factors
gram
amida
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92901892T
Other languages
English (en)
Inventor
Paolo Tavecchia
Sergio Lociuro
Romeo Ciabatti
Enrico Selva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of ES2067325T3 publication Critical patent/ES2067325T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)

Abstract

EL PRESENTE INVENTO DE REFIERE A LOS NUEVOS DERIVADOS DE AMIDA DE ANTIBIOTICO GE 2270, Y COMPUESTOS PARA SU PREPARACION. DICHOS DERIVADOS DE AMIDA, SON AGENTES ACTIVOS ANTIMICROBIANOS CONTRA BACTERIAS GRAM GRAM
ES92901892T 1991-01-03 1992-01-02 Amidas de factores del antibiotico ge 2270. Expired - Lifetime ES2067325T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91100123 1991-01-03

Publications (1)

Publication Number Publication Date
ES2067325T3 true ES2067325T3 (es) 1995-03-16

Family

ID=8206281

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92901892T Expired - Lifetime ES2067325T3 (es) 1991-01-03 1992-01-02 Amidas de factores del antibiotico ge 2270.

Country Status (18)

Country Link
US (1) US5599791A (es)
EP (2) EP0565567B1 (es)
JP (1) JP3183508B2 (es)
KR (1) KR100225763B1 (es)
CN (1) CN1063110A (es)
AT (1) ATE117320T1 (es)
AU (1) AU662122B2 (es)
CA (1) CA2093219C (es)
DE (1) DE69201236T2 (es)
ES (1) ES2067325T3 (es)
FI (1) FI932944L (es)
HU (1) HU224072B1 (es)
IE (1) IE920005A1 (es)
IL (1) IL100572A (es)
MX (1) MX9200015A (es)
NZ (1) NZ241216A (es)
WO (1) WO1992012172A1 (es)
ZA (1) ZA927B (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2071143T3 (es) * 1990-03-08 1995-06-16 Lepetit Spa Factores b1, b2, c1, c2, d1, d2, e y t del antibiotico ge 2270.
ATE163428T1 (de) * 1991-08-30 1998-03-15 Biosearch Italia Spa Faktor c2a des antibiotikums ce 2270
US5882900A (en) * 1992-09-10 1999-03-16 Gruppo Lepetit S.P.A. Process for the selective increase of production of antibiotic GE 2270 factor a by adding vitamin B12 to nutrient medium
CA2151616A1 (en) * 1992-12-22 1994-07-07 Sergio Stella Antibiotics ge 37468 a, b and c
US5891869A (en) * 1995-02-07 1999-04-06 Biosearch Italia, S.P.A. Basic oxazoline-amide derivatives of GE2270 and GE2270-like antibiotics
CA2212372A1 (en) * 1995-02-07 1996-08-15 Biosearch Italia S.P.A. Basic proline-amide derivatives of ge 2270 and ge 2270-like antibiotics
US6008225A (en) * 1996-02-14 1999-12-28 Biosearch Italia, S.P.A. Derivatives of antibiotic GE2270 factors C2a, D2 and E
JPH1059997A (ja) * 1996-08-22 1998-03-03 Microbial Chem Res Found アミチアマイシンアミド誘導体
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
GB0024200D0 (en) * 2000-10-03 2000-11-15 Smithkline Beecham Sa Component vaccine
EP1553967B1 (en) * 2002-06-17 2011-05-18 NAICONS s.c.a.r.l. Use of amide derivative of ge 2270 factor a3 for the treatment of acne
EP1620098B1 (en) 2003-04-30 2008-06-11 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections
AU2004299278C9 (en) 2003-12-18 2013-10-24 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
CN1926240B (zh) * 2004-01-19 2010-06-02 帝斯曼知识产权资产管理有限公司 6-氨基己酸的生物化学合成
AR060977A1 (es) * 2006-05-31 2008-07-23 Novartis Ag Aminotiazoles y sus usos
EP2097423B1 (en) * 2006-12-20 2011-03-02 Novartis AG Aminothiazole macrocycles, their use as antibacterial compounds and processes for their production
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
US8476224B2 (en) 2007-06-04 2013-07-02 Novartis Ag Macrocycles and their uses
CA2696018A1 (en) 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
CA2708793C (en) * 2007-12-12 2016-06-21 Novartis Ag Aminothiazoles and their uses
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
JP5755884B2 (ja) 2008-03-05 2015-07-29 ジェノマティカ， インコーポレイテッド 第一級アルコールを産生する生物
SI2265709T1 (en) 2008-03-27 2018-03-30 Genomatica, Inc. MICROORGANISMS FOR PREPARATION OF ADYPIC ACID AND OTHER COMPOUNDS
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ， インコーポレイテッド メタクリル酸の産生のための微生物
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
KR20110097951A (ko) 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
BRPI1013426A2 (pt) 2009-04-30 2016-11-08 Genomatica Inc organismos para produção de 1,3-butanodiol
US8993285B2 (en) 2009-04-30 2015-03-31 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
ES2749423T3 (es) 2009-05-07 2020-03-20 Genomatica Inc Microorganismos y métodos para la biosíntesis de adipato, hexametilendiamina y ácido 6-aminocaproico
EP2429587A4 (en) 2009-05-15 2014-10-08 Genomatica Inc ORGANISMS FOR THE PREPARATION OF CYCLOHEXANONE
JP2012529889A (ja) 2009-06-10 2012-11-29 ゲノマチカ， インク． Ｍｅｋ及び２−ブタノールの炭素効率のよい生合成のための微生物及び方法
EP2462221B1 (en) 2009-08-05 2017-02-22 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
BR112012005296A2 (pt) 2009-09-09 2019-01-15 Genomatica Inc microorganismos e métodos para a coprodução de isopropanol com alcoóis primários, diós e ácidos.
AU2010306785B2 (en) 2009-10-13 2016-01-14 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
CN109136161A (zh) 2009-12-10 2019-01-04 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
CA2787314A1 (en) 2010-01-29 2011-08-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
MX336229B (es) 2010-05-05 2016-01-08 Genomatica Inc Microorganismos y metodos para la biosintesis de butadieno.
JP2013535203A (ja) 2010-07-26 2013-09-12 ジェノマティカ・インコーポレイテッド 芳香族、２，４−ペンタジエノエートおよび１，３−ブタジエンを生合成するための微生物および方法
EP3628676A1 (en) * 2018-09-28 2020-04-01 Université de Montpellier Modified peptides and their uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69016284T2 (de) * 1989-07-04 1995-05-24 Lepetit Spa Antibiotikum GE 22270, Faktoren A1,A2,A3 und H.

Also Published As

Publication number Publication date
AU662122B2 (en) 1995-08-24
CN1063110A (zh) 1992-07-29
EP0494078A1 (en) 1992-07-08
IL100572A0 (en) 1992-09-06
US5599791A (en) 1997-02-04
ATE117320T1 (de) 1995-02-15
FI932944A0 (fi) 1993-06-24
DE69201236D1 (de) 1995-03-02
NZ241216A (en) 1994-04-27
MX9200015A (es) 1992-07-31
KR930703355A (ko) 1993-11-29
EP0565567B1 (en) 1995-01-18
IE920005A1 (en) 1992-07-15
JP3183508B2 (ja) 2001-07-09
KR100225763B1 (ko) 1999-10-15
FI932944A7 (fi) 1993-06-24
HU9301941D0 (en) 1993-09-28
HUT64085A (en) 1993-11-29
HU224072B1 (hu) 2005-05-30
JPH06504768A (ja) 1994-06-02
EP0565567A1 (en) 1993-10-20
DE69201236T2 (de) 1995-06-01
WO1992012172A1 (en) 1992-07-23
CA2093219A1 (en) 1992-07-04
CA2093219C (en) 2002-04-09
AU1154492A (en) 1992-08-17
FI932944L (fi) 1993-06-24
IL100572A (en) 1997-01-10
ZA927B (en) 1992-09-30

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