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ES2161368T3 - Composicion de gel de polisacarido. - Google Patents

Composicion de gel de polisacarido.

Info

Publication number
ES2161368T3
ES2161368T3 ES96923119T ES96923119T ES2161368T3 ES 2161368 T3 ES2161368 T3 ES 2161368T3 ES 96923119 T ES96923119 T ES 96923119T ES 96923119 T ES96923119 T ES 96923119T ES 2161368 T3 ES2161368 T3 ES 2161368T3
Authority
ES
Spain
Prior art keywords
gel
composition
polisacarido
polisacaride
overcurrence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96923119T
Other languages
English (en)
Inventor
Med Ab Q
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Q Med AB
Original Assignee
Q Med AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24001615&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2161368(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Q Med AB filed Critical Q Med AB
Application granted granted Critical
Publication of ES2161368T3 publication Critical patent/ES2161368T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075Macromolecular gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Materials For Medical Uses (AREA)
  • Colloid Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

LA PRESENTE INVENCION PRESENTA UN PROCESO PARA PREPARAR UNA COMPOSICION BIOCOMPATIBLE DE GEL DE POLISACARIDOS CON PUENTES CRUZADOS, QUE CONSISTE EN LA FORMACION DE UNA SOLUCION ACUOSA DE UN POLISACARIDO HIDROSOLUBLE CON PUENTES CRUZADOS; EL INICIO DE SOBRECRUZAMIENTO DE DICHO POLISACARIDOS EN PRESENCIA DE UN AGENTE POLIFUNCIONAL DE SOBRECRUZAMIENTO; LA OBSTRUCCION ESTERICA DE LA TERMINACION DE LA REACCION DE SOBRECRUZAMIENTO ANTES DE PRODUCIRSE LA GELIFICACION, OBTENIENDOSE UN POLISACARIDO ACTIVADO; Y LA REINTRODUCCION DE CONDICIONES NO OBSTACULIZADAS ESTERICAMENTE DE DICHO POLISACARIDO ACTIVADO PARA CONTINUAR EL SOBRECRUZAMIENTO HASTA OBTENER UN GEL VISCOELASTICO. LA INVENCION PRESENTA TAMBIEN UNA COMPOSICION DE GEL QUE PUEDE OBTENERSE MEDIANTE DICHO PROCESO ASI COMO COMPOSICIONES DE GELES PARA DIFERENTES USOS MEDICOS.
ES96923119T 1995-07-17 1996-05-28 Composicion de gel de polisacarido. Expired - Lifetime ES2161368T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/503,323 US5827937A (en) 1995-07-17 1995-07-17 Polysaccharide gel composition

Publications (1)

Publication Number Publication Date
ES2161368T3 true ES2161368T3 (es) 2001-12-01

Family

ID=24001615

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96923119T Expired - Lifetime ES2161368T3 (es) 1995-07-17 1996-05-28 Composicion de gel de polisacarido.

Country Status (25)

Country Link
US (1) US5827937A (es)
EP (1) EP0839159B1 (es)
JP (1) JP3094074B2 (es)
KR (1) KR100314488B1 (es)
CN (1) CN1083849C (es)
AT (1) ATE204000T1 (es)
BR (2) BR9609534B1 (es)
CA (1) CA2226488C (es)
CZ (1) CZ290755B6 (es)
DE (2) DE69614391T2 (es)
DK (1) DK0839159T3 (es)
EA (1) EA001500B1 (es)
ES (1) ES2161368T3 (es)
GR (1) GR3037065T3 (es)
HU (1) HU220257B (es)
MX (1) MX9800484A (es)
NO (1) NO315274B1 (es)
NZ (1) NZ312229A (es)
PL (1) PL188071B1 (es)
PT (1) PT839159E (es)
SI (1) SI0839159T1 (es)
SK (1) SK282431B6 (es)
TR (1) TR199800072T1 (es)
UA (1) UA48980C2 (es)
WO (1) WO1997004012A1 (es)

Families Citing this family (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7060287B1 (en) * 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
EP0910348B1 (en) * 1996-05-23 2003-04-02 Samyang Corporation Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
EP0999854B1 (en) 1997-07-29 2003-10-01 Alcon Manufacturing Ltd. Switchable viscoelastic systems containing galactomannan polymers and borate
GB9902412D0 (en) 1999-02-03 1999-03-24 Fermentech Med Ltd Process
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
KR100721752B1 (ko) 2000-01-24 2007-05-25 쿠라레 메디카루 가부시키가이샤 수팽윤성 고분자 겔 및 그 제조법
SE0004928D0 (sv) * 2000-12-29 2000-12-29 Apbiotech Ab A method for the manufacturing of porous material
FR2819722B1 (fr) * 2001-01-19 2006-11-24 Corneal Ind Utilisation de l'acide hyaluronique ou d'au moins l'un de ses sels dans le cadre d'un traitemnet chirurgical de la presbytie
US8580290B2 (en) * 2001-05-08 2013-11-12 The Board Of Regents Of The University Of Oklahoma Heparosan-based biomaterials and coatings and methods of production and use thereof
US20070078435A1 (en) * 2001-06-14 2007-04-05 Corbett Stone Tissue augmentation methods using a medical injection apparatus
EP1453909B1 (en) 2001-12-11 2007-10-03 Ceapro Inc. Cereal beta glucan compositions, methods of preparation and uses thereof
KR20040009891A (ko) * 2002-07-26 2004-01-31 주식회사 엘지생명과학 히알루론산의 유도체 겔 및 그 제조방법
US7816316B2 (en) * 2002-11-21 2010-10-19 Chugai Seiyaku Kabushiki Kaisha Sustained release drug carrier
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
JP2004323454A (ja) * 2003-04-25 2004-11-18 Chisso Corp 薬剤
EP1648942A2 (fr) * 2003-07-30 2006-04-26 Anteis S.A. Matrice complexe a usage biomedical
EP1681306B1 (en) * 2003-10-29 2013-02-20 Teijin Limited Hyaluronic acid compound, hydrogel thereof and material for treating joint
JP4745826B2 (ja) * 2003-11-14 2011-08-10 中外製薬株式会社 架橋多糖微粒子およびその製造方法
US8124120B2 (en) * 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US8524213B2 (en) * 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
FR2865737B1 (fr) * 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
SE0401182D0 (sv) * 2004-05-05 2004-05-05 Q Med Ab Novel use of a viscoelastic composition
WO2005113608A1 (en) 2004-05-20 2005-12-01 Mentor Corporation Method of covalently linking hyaluronan and chitosan
FR2871692B1 (fr) * 2004-06-22 2007-08-03 Epitact Md Sa Procede et dispositif pour accelerer la croissance des phaneres, notamment des ongles
WO2006028110A1 (ja) 2004-09-07 2006-03-16 Chugai Seiyaku Kabushiki Kaisha 水溶性ヒアルロン酸修飾物の製造方法
EP1818344A4 (en) * 2004-11-15 2012-04-18 Shiseido Co Ltd METHOD FOR SYNTHESIZING RETICULATED HYALURONIC ACID GEL
US20060105022A1 (en) * 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
CN101094680A (zh) 2004-12-30 2007-12-26 建新公司 用于关节内粘弹性补充的方案
CA2607004C (en) 2005-05-05 2016-01-26 Sensient Flavors Inc. Production of beta-glucans and mannans
WO2006138563A1 (en) * 2005-06-16 2006-12-28 Artes Medical, Inc. Liquid crystal polymer syringes and containers and methods of use for long term storage of filler materials
KR101250846B1 (ko) * 2005-07-04 2013-04-05 주식회사 엘지생명과학 히알루론산 가교물의 제조방법
US20070102010A1 (en) * 2005-10-07 2007-05-10 Lemperle Stefan M Naso-pharyngeal tissue engineering
CN100379763C (zh) * 2006-01-12 2008-04-09 武汉大学 交联茯苓多糖及其制备方法和用途
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US20070212385A1 (en) * 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
DE102006013594A1 (de) * 2006-03-22 2007-09-27 Biopolymer Gmbh & Co. Kg Quervernetzte Gele von Hyaluronsäure und deren Verwendung
EP2543340A1 (en) * 2006-05-19 2013-01-09 Trustees Of Boston University Novel hydrophilic polymers as medical lubricants and gels
FR2909285A1 (fr) * 2006-12-01 2008-06-06 Anteis Sa "utilisation d'un gel anti-adhesif et anti fibrotique"
US8987230B2 (en) * 2007-05-01 2015-03-24 National University Corporation Tokyo Medical And Dental University Hybrid gel comprising chemically crosslinked hyaluronic acid derivative and pharmaceutical composition comprising the same
US8672918B2 (en) * 2007-05-16 2014-03-18 Ipsyrng Capital Development, Llc Methods for identifying areas of a subject's skin that appear to lack volume
US8658148B2 (en) * 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
FR2918377B1 (fr) * 2007-07-05 2010-10-08 Estelle Piron Gel co-reticule de polysaccharides
US20090023631A1 (en) * 2007-07-18 2009-01-22 Lorenc Z Paul Composition and Method of Use for Soft Tissue Augmentation/Drug Delivery
US8455459B2 (en) * 2007-08-02 2013-06-04 Medicis Pharmaceutical Corporation Method of applying an injectable filler
US20090204101A1 (en) * 2007-08-20 2009-08-13 Wortzman Mitchell S Method of applying an injectable filler
ES2381417T3 (es) 2007-09-28 2012-05-28 Shiseido Company, Ltd. Polvo de ácido hialurónico reticulado hinchable y procedimiento para fabricarlo
WO2009044403A2 (en) * 2007-10-05 2009-04-09 Juvenis Ltd. Injectable biodegradable polymer compositions for soft tissue repair and augmentation
BRPI0819075A2 (pt) 2007-11-16 2014-10-07 Vicept Therapeutics Inc Método para tratar púrpura em um indivíduo e método para diminuir a púrpura em um indivíduo antes de um procedimento cirúrgico
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US9687559B2 (en) * 2008-03-19 2017-06-27 The Board Of Regents Of The University Of Oklahoma Heparosan polymers and methods of making and using same for the enhancement of therapeutics
US9925209B2 (en) 2008-03-19 2018-03-27 The Board Of Regents Of The University Of Oklahoma Heparosan-polypeptide and heparosan-polynucleotide drug conjugates and methods of making and using same
GB2469219A (en) * 2008-04-10 2010-10-06 Kythera Biopharmaceuticals Inc Dermal filler composition
US8932622B2 (en) * 2008-06-03 2015-01-13 Actamax Surgical Materials, Llc Tissue coating for preventing undesired tissue-to-tissue adhesions
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
WO2010028025A1 (en) 2008-09-02 2010-03-11 Gurtner Geoffrey C Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
CN101445566B (zh) * 2008-12-11 2011-05-04 彭秀兰 No增放剂精氨酸氨基多糖及其生产方法
US9173975B2 (en) * 2009-04-24 2015-11-03 Ingeneron, Inc. Reparative cell delivery via hyaluronic acid vehicles
IT1395392B1 (it) 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
US8273725B2 (en) 2009-09-10 2012-09-25 Genzyme Corporation Stable hyaluronan/steroid formulation
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
EP2498763A4 (en) 2009-11-09 2015-10-07 Spotlight Technology Partners Llc HYDROGELE ON POLYSACCHARIDBASIS
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
CA2792729C (en) 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
WO2011154759A1 (en) * 2010-06-08 2011-12-15 Dow Global Technologies Llc Method for the preparation of a particulate reversibly crosslinked polymeric material
US9017712B2 (en) 2010-07-12 2015-04-28 Shin Poong Pharmaceutical Co., Ltd. Filler composition for tissue reinforcement
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
CA2809893A1 (en) * 2010-09-02 2012-03-08 Mcmaster University Hyaluronic acid-containing biopolymers
FR2968996B1 (fr) 2010-12-17 2013-04-12 Anteis Sa Formulation aqueuse injectable sterile utilisee en ophtalmologie
EP2484387A1 (en) 2011-02-03 2012-08-08 Q-Med AB Hyaluronic acid composition
WO2012131095A1 (en) 2011-03-31 2012-10-04 Galderma Research & Development Compositions comprising a filler product and at least one bioresorbable and biodegradable silica-based material
WO2012146031A1 (zh) * 2011-04-26 2012-11-01 北京爱美客生物科技有限公司 透明质酸与羟丙基甲基纤维素复合凝胶及制备方法
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9149422B2 (en) 2011-06-03 2015-10-06 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
EP2736545B1 (en) 2011-07-28 2016-01-06 Harbor Medtech, Inc. Crosslinked human or animal tissue products and their methods of manufacture and use
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
EP2581079B1 (en) * 2011-10-11 2016-12-07 BioPolymer GmbH & Co. KG Combination of hyaluronic acid and prilocaine
ITAN20110138A1 (it) 2011-10-12 2012-01-11 Regenyal Lab S R L Sintesi di un gel iniettabile multifasico a base di acido ialuronico monofasico libero e reticolato e di acido ialuronico bifasico associato con idrossiapatite con inibitore della ialuronidasi microincapsulato.
EP2776077A4 (en) * 2011-11-11 2014-12-17 Miba Medical Inc INJECTABLE FILLING MATERIAL
AU2013232380A1 (en) 2012-03-12 2014-09-25 The Regents Of The University Of California Methods and compositions for treating wounds and reducing the risk of incisional hernias
KR101240518B1 (ko) 2012-03-26 2013-03-11 주식회사 제네웰 생체 적합성 고분자를 이용한 이식용 재료
AU2013237894B2 (en) 2012-03-30 2018-06-21 The Board Of Regents Of The University Of Oklahoma High molecular weight heparosan polymers and methods of production and use thereof
CN102614111B (zh) * 2012-04-05 2013-11-06 苏州豫源生物医药有限公司 氨基葡萄糖的凝胶剂及其制备方法
ITMI20120732A1 (it) 2012-05-03 2013-11-04 B S Srl Polisaccaridi reticolati a memoria di forma
ITPD20120173A1 (it) 2012-05-31 2013-12-01 Fidia Farmaceutici "nuovo sistema di rilascio di proteine idrofobiche"
EP2861626B1 (en) * 2012-06-15 2018-12-19 Merz Pharma GmbH & Co. KGaA Method of preparing a composition based on hyaluronic acid
JP5840107B2 (ja) 2012-06-17 2016-01-06 コスメディ製薬株式会社 ヒアルロン酸ゲル及びその製造方法
KR20150104202A (ko) 2013-01-11 2015-09-14 카르빌란 테라퓨틱스, 인코포레이티드 히알루론산을 포함하는 안정화된 조성물
CN103146003A (zh) * 2013-03-06 2013-06-12 上海其胜生物制剂有限公司 一种低温二次交联透明质酸钠凝胶的制备方法
KR101869988B1 (ko) * 2013-03-27 2018-06-21 주식회사 엘지화학 점탄성 히알루론산 가교물 제조용 조성물, 및 이를 이용하여 얻은 히알루론산 가교물
EP2996709B1 (en) 2013-05-15 2020-05-06 The Board of Trustees of the Leland Stanford Junior University Modulation of heparin-binding epidermal growth factor activity for tympanic membrane healing
WO2014198406A1 (en) 2013-06-11 2014-12-18 Anteis S.A. Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel
MX368941B (es) * 2013-06-28 2019-10-22 Galderma Sa Un procedimiento para preparar un producto de ácido hialurónico entrelazado.
MX369409B (es) * 2013-06-28 2019-11-07 Galderma Sa Método para la fabricación de un producto perfilado de ácido hialurónico.
US10639266B2 (en) 2013-07-03 2020-05-05 Ritapharma, Co., Ltd Water-soluble hyaluronic acid gel and method for producing same
ES2653549T3 (es) 2013-09-30 2018-02-07 Galderma S.A. Funcionalización y reticulación de ácido hialurónico en un paso
KR101459070B1 (ko) 2013-12-09 2014-11-17 (주) 뉴메딕 지속성을 갖는 히알루론산 겔 조성물
AR099900A1 (es) 2014-04-01 2016-08-24 Merz Pharma Gmbh & Co Kgaa Rellenos para tejidos blandos con polisacáridos con persistencia mejorada, kit, procedimiento, uso
US20170210829A1 (en) * 2014-05-29 2017-07-27 Galderma S.A. Cross-linked polymer mixture of hyaluronic acid and dextran grafted with cyclodextrins and uses thereof
KR20170026377A (ko) 2014-05-29 2017-03-08 갈데르마 소시에떼아노님 덱스트란과 그래프트된 가교된 히알루론산
WO2016030516A1 (en) 2014-08-29 2016-03-03 Galderma S.A. Enantiopure or enantioenriched bdde and its use as crosslinking agent in the manufacture of cross-linked products
EP3620184A1 (en) 2014-09-30 2020-03-11 Allergan Industrie, SAS Stable hydrogel compositions including additives
US20170290947A1 (en) * 2014-10-08 2017-10-12 Therakine Bio Delivery GmbH Micronized hydrophilic cross-linked biopolymer systems and method of making same
CA2970853A1 (en) 2014-12-18 2016-06-23 Galderma S.A. Grafting of cyclodextrin by amide bonds to an ether cross-linked hyaluronic acid and uses thereof
EP3040118A1 (en) 2014-12-29 2016-07-06 Galderma S.A. Ether cross-linked chondroitin hydrogels and their use for soft tissue applications
EP3040348A1 (en) 2014-12-29 2016-07-06 Galderma S.A. Graft copolymer
EP3040117A1 (en) 2014-12-29 2016-07-06 Galderma S.A. Ether cross-linked chondroitin sulfate hydrogels and their use for soft tissue applications
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
EP3653232A1 (en) 2015-02-13 2020-05-20 Allergan Industrie, SAS Implants for sculpting, augmenting or correcting facial features such as the chin
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
EP3302591B1 (en) 2015-05-29 2020-12-30 Galderma S.A. Mixed hydrogels of hyaluronic acid and dextran
EP3307237A1 (en) 2015-06-12 2018-04-18 Laboratoire Français du Fractionnement et des Biotechnologies Injectable composition of factor vii and fillers
FR3037797B1 (fr) 2015-06-24 2018-08-17 Kylane Laboratoires Sa Procede de preparation d'un hydrogel reticule injectable; hydrogel obtenu; utilisation de l'hydrogel obtenu
US9737395B2 (en) 2015-06-26 2017-08-22 Phi Nguyen Systems and methods for reducing scarring
EP3316911B1 (en) 2015-06-30 2020-11-04 Merz Pharma GmbH & Co. KGaA Method of preparing a composition based on hyaluronic acid
KR20170025778A (ko) 2015-08-31 2017-03-08 대화제약 주식회사 항산화제를 포함하는 생체 적합성 고분자 히알루론산 유도체 및 그 히알루론산의 가교결합물
KR101720426B1 (ko) 2015-09-01 2017-04-14 (주)시지바이오 히알루론산 조성물 및 그의 제조방법
CN105126157B (zh) * 2015-09-17 2018-02-09 爱美客技术发展股份有限公司 医用可注射粘合凝胶及其制备方法
FR3044557B1 (fr) 2015-12-07 2017-12-01 Benedicte Vincente Gavard Molliard Tauzin Nouvelle composition injectable; procede de preparation de ladite composition; utilisation de ladite composition
FR3047666A1 (fr) 2016-02-15 2017-08-18 Benedicte Vincente Gavard Molliard Tauzin Composition injectable; procede de preparation de ladite composition; utilisation de ladite composition
KR101866310B1 (ko) 2016-05-31 2018-06-11 주식회사 글랜젠 생체 내 지속성 및 항산화 작용이 향상된 진피 충전재 조성물 및 이의 제조방법
EP3475312B1 (en) 2016-06-23 2020-05-27 Galderma S.A. Cyclodextrin-grafted cross-linked hyaluronic acid complexed with active drug substances and uses thereof
WO2018024795A1 (en) 2016-08-03 2018-02-08 Galderma Research & Development Method of crosslinking glycosaminoglycans
HUE050368T2 (hu) 2016-08-03 2020-11-30 Galderma Res & Dev Eljárás glükózaminoglikánok elõállítására
JP2019532708A (ja) 2016-09-21 2019-11-14 ネスレ スキン ヘルス エス アー 二価の亜鉛カチオンを含むヒアルロン酸ゲル
AR110125A1 (es) 2016-11-07 2019-02-27 Croma Pharma Ges M B H Compuestos poliméricos que liberan sulfuro de hidrógeno
EP3494146A1 (en) 2016-12-23 2019-06-12 Galderma Research & Development Double crosslinked glycosaminoglycans
WO2018122344A1 (en) 2016-12-29 2018-07-05 Nestlé Skin Health Sa Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis
EP3562468A1 (en) 2016-12-29 2019-11-06 Nestlé Skin Health SA Micro- or nanoparticular multilamellar vesicles, compositions comprising the same and method for their use in skin care
WO2018122343A1 (en) 2016-12-29 2018-07-05 Nestlé Skin Health Sa Micro- or nanoparticular vesicles comprising crosslinked hyaluronic acid, compositions comprising the same and method for their use in skin care
IT201700008651A1 (it) 2017-01-26 2018-07-26 Beauty System Pharma Ltd Acido ialuronico reticolato con agenti reticolanti di tipo naturale o semisintetico
CN108721206B (zh) * 2017-04-14 2021-11-09 常州药物研究所有限公司 治疗膀胱输尿管返流、压力性尿失禁和大便失禁的组合物及其制备方法
WO2018220283A1 (fr) 2017-05-29 2018-12-06 Kh Medtech Sarl Composition injectable sterile contenant de l'acide hyaluronique reticule et de l'articaine
WO2019002371A1 (en) 2017-06-28 2019-01-03 Nestlé Skin Health Sa GLYCOSAMINOGLYCAN GEL WITH BIS-TRIS BUFFER
WO2019001784A1 (en) 2017-06-28 2019-01-03 Nestlé Skin Health Sa Hyaluronic acid gel with a divalent cation
WO2019121694A1 (en) 2017-12-22 2019-06-27 Nestlé Skin Health Sa Injectable compositions of cross-linked hyaluronic acid and bupivacaine, and uses thereof
IL306070A (en) 2018-05-03 2023-11-01 Collplant Ltd Dermal fillers and their uses
RS66897B1 (sr) 2018-07-06 2025-07-31 Lg Chemical Ltd Filer hijaluronske kiseline visoke viskoelastičnosti i visoke kohezivnosti
WO2020013580A1 (ko) 2018-07-10 2020-01-16 주식회사 엘지화학 높은 리프트 능력 및 낮은 주입력을 갖는 히알루론산 필러
KR20200046649A (ko) 2018-10-25 2020-05-07 (주)뉴크레이티브랩 혼합상 히알루론산 제조방법
CN113164652B (zh) 2018-12-20 2023-02-21 株式会社Lg化学 具有优异的填充剂性能的包含透明质酸水凝胶的填充剂
TWI797405B (zh) 2018-12-21 2023-04-01 南韓商Lg化學股份有限公司 具有經改善之填充性質的包含玻尿酸水凝膠之填料
EP3946484B1 (en) 2019-04-02 2023-11-15 Volumina Medical SA Composition comprising a cross-linked polyol
TR201922907A2 (tr) * 2019-12-31 2021-07-26 Vsy Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi Osteoartri̇t tedavi̇si̇ i̇çi̇n yeni̇ bi̇r vi̇skoelasti̇k formülasyonu ve bunun üreti̇m yöntemi̇
US12102731B2 (en) 2020-05-01 2024-10-01 Harbor Medtech, Inc. Port-accessible multidirectional reinforced minimally invasive collagen device for soft tissue repair
KR102425496B1 (ko) 2020-05-08 2022-07-26 주식회사 종근당 고탄성, 고점도 및 고유효 가교율을 갖는 히알루론산 가교체, 및 이의 제조방법
EP4400125A4 (en) 2021-09-09 2025-08-13 Sunbio Inc SOL-GEL TRANSITION OF 6-ARM PEG HYDROGEL OVER TIME
IT202100032111A1 (it) 2021-12-22 2023-06-22 Fidia Farm Spa Nuovi sostituti biocompatibili dell’umor vitreo
EP4473021A1 (en) 2022-02-01 2024-12-11 Galderma Holding SA Methods of producing crosslinked hyaluronic acid hydrogels
US12312447B2 (en) 2023-06-19 2025-05-27 Zhejiang Triple Win New Material Co., Ltd. Preparation method for polysaccharide spherical gel resin
WO2025086125A1 (en) 2023-10-25 2025-05-01 L'oreal Composition for conditioning keratin fibers

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4197846A (en) * 1974-10-09 1980-04-15 Louis Bucalo Method for structure for situating in a living body agents for treating the body
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
GB8412423D0 (en) * 1984-05-16 1984-06-20 Allied Colloids Ltd Polymeric compositions
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
US4863907A (en) * 1984-06-29 1989-09-05 Seikagaku Kogyo Co., Ltd. Crosslinked glycosaminoglycans and their use
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
SE458525B (sv) * 1985-05-23 1989-04-10 Pharmacia Ab Foerfarande foer tvaerbindning av en poroes agar- eller agarosgel
SE452469B (sv) * 1986-06-18 1987-11-30 Pharmacia Ab Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US4767463A (en) * 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5007940A (en) * 1989-06-09 1991-04-16 American Medical Systems, Inc. Injectable polymeric bodies
US5143724A (en) * 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5246698A (en) * 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
CA2158638C (en) * 1993-03-19 1999-11-30 Bengt Agerup A composition and a method for tissue augmentation

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HUP9901714A2 (hu) 1999-09-28
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