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MX369409B - Método para la fabricación de un producto perfilado de ácido hialurónico. - Google Patents

Método para la fabricación de un producto perfilado de ácido hialurónico.

Info

Publication number
MX369409B
MX369409B MX2015017526A MX2015017526A MX369409B MX 369409 B MX369409 B MX 369409B MX 2015017526 A MX2015017526 A MX 2015017526A MX 2015017526 A MX2015017526 A MX 2015017526A MX 369409 B MX369409 B MX 369409B
Authority
MX
Mexico
Prior art keywords
hyaluronic acid
cross
shaped cross
acid product
manufacturing
Prior art date
Application number
MX2015017526A
Other languages
English (en)
Other versions
MX2015017526A (es
Inventor
Karlsson Morgan
Helander Kenne Anne
Öhrlund Åke
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of MX2015017526A publication Critical patent/MX2015017526A/es
Publication of MX369409B publication Critical patent/MX369409B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Neurosurgery (AREA)
  • Textile Engineering (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)

Abstract

La presente invención se refiere a un método para fabricar un producto perfilado de ácido hialurónico entrelazado que comprende el paso de someter un sustrato de ácido hialurónico, precipitado, no entrelazado en un perfil deseado a una única reacción de entrelazamiento en un medio líquido que tiene un pH de 11.5 o superior y que comprende uno o más agentes de entrelazado polifuncionales y una cantidad de uno o más solventes orgánicos que dan condiciones precipitantes para el ácido hialurónico, bajo condiciones adecuadas para obtener un producto perfilado, precipitado de ácido hialurónico entrelazado que tiene un grado de modificación de 1-40 de unidades de agente de entrelazado por 1000 unidades de disacáridos.
MX2015017526A 2013-06-28 2013-06-28 Método para la fabricación de un producto perfilado de ácido hialurónico. MX369409B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2013/063716 WO2014206500A1 (en) 2013-06-28 2013-06-28 Method for manufacturing a shaped cross-linked hyaluronic acid product

Publications (2)

Publication Number Publication Date
MX2015017526A MX2015017526A (es) 2016-08-05
MX369409B true MX369409B (es) 2019-11-07

Family

ID=48703545

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015017526A MX369409B (es) 2013-06-28 2013-06-28 Método para la fabricación de un producto perfilado de ácido hialurónico.

Country Status (11)

Country Link
US (4) US10077321B2 (es)
EP (2) EP3617236B1 (es)
JP (1) JP6434003B2 (es)
KR (1) KR102048395B1 (es)
CN (2) CN105473622B (es)
AU (1) AU2013396752B2 (es)
BR (1) BR112015031589A2 (es)
CA (1) CA2916119A1 (es)
MX (1) MX369409B (es)
RU (1) RU2640865C2 (es)
WO (1) WO2014206500A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210402050A1 (en) * 2020-06-24 2021-12-30 Anika Therapeutics, Inc. Composite medical textile with non-resorbable fibers and bioresorbable hyaluronan-based fibers
JP6754378B2 (ja) 2015-02-13 2020-09-09 エンドダーマ カンパニー リミテッドＥｎｄｏｄｅｒｍａ Ｃｏ．，Ｌｔｄ． 架橋されたヒアルロン酸ハイドロゲルを用いたマイクロ構造体及びその製造方法
EP3328351A1 (en) 2015-07-27 2018-06-06 Galderma S.A. A process for efficient cross-linking of hyaluronic acid
KR101709608B1 (ko) * 2015-09-03 2017-03-09 (주)진우바이오 용융 방사에 의한 히알루론산염 파이버의 제조방법 및 이로부터 제조된 히알루론산염 파이버
EP3350240B1 (en) 2015-09-18 2023-08-09 Arkema, Inc. Polyol pre-mixes having improved shelf life
KR20170090965A (ko) * 2016-01-29 2017-08-08 한미약품 주식회사 복합 히알루론산 가교물 및 그 제조방법
EP3528858B1 (en) * 2016-10-18 2020-10-21 Aarhus Universitet Printed hyaluronic acid scaffolds
EP3562469A1 (en) 2016-12-29 2019-11-06 Nestlé Skin Health SA Micro- or nanoparticular vesicles comprising crosslinked hyaluronic acid, compositions comprising the same and method for their use in skin care
WO2018122344A1 (en) 2016-12-29 2018-07-05 Nestlé Skin Health Sa Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis
WO2018122342A1 (en) * 2016-12-29 2018-07-05 Nestlé Skin Health Sa Micro- or nanoparticular multilamellar vesicles, compositions comprising the same and method for their use in skin care
AR111190A1 (es) 2017-03-22 2019-06-12 Genentech Inc Composiciones en hidrogel de prodrogas entrecruzadas de ácido hialurónico y métodos relacionados
WO2019073364A1 (en) * 2017-10-12 2019-04-18 Solyplus Berlin Gmbh CROSSLINKING BIOPOLYMERS IN A SEMI-SOLID STATE
WO2019238954A1 (en) * 2018-06-15 2019-12-19 Croma-Pharma Gmbh Hydrogel composition comprising a crosslinked polymer
BR112021018691A2 (pt) * 2019-03-24 2021-11-23 Allergan Pharmaceuticals Int Ltd Géis homogêneos injetáveis compreendendo formas múltiplas de ácido hialurônico e métodos para sua fabricação
US20220213233A1 (en) * 2019-04-19 2022-07-07 Jointherapeutics S.R.L. Crosslinked polymer of functionalized hyaluronic acid and its use in the treatment of inflammatory states
EP3797800A1 (en) * 2019-05-02 2021-03-31 Institut National De La Sante Et De La Recherche Medicale - Inserm Hyaluronic acid hydrogels with prolonged antimicrobial activity
WO2020234167A1 (en) * 2019-05-17 2020-11-26 ETH Zürich Printable hydrogel, method for generating a printable hydrogel, lyophilizate, printed product and 3d printing method
CN112147029A (zh) * 2019-06-28 2020-12-29 杭州协合医疗用品有限公司 一种交联透明质酸钠凝胶溶胀度的测定方法
US20220298310A1 (en) * 2019-09-27 2022-09-22 Lg Chem, Ltd. A method of preparing polymeric microparticles, polymeric microparticles, medical composition, cosmetic composition, medical articles and cosmetic articles using the same
KR102173790B1 (ko) * 2020-02-26 2020-11-03 (주) 제이피케어즈 가교 히알루론산을 이용한 약물 전달 조성물 및 이의 제조방법
EP4253614A4 (en) * 2020-11-26 2024-10-30 Jinwoo Bio Co., Ltd. HYALURONATE FIBER AND PRODUCTION PROCESS THEREOF
KR102527095B1 (ko) 2020-12-18 2023-04-28 충남대학교산학협력단 가교 처리된 히알루론산 조성물의 가교율 측정방법
CN113045779B (zh) * 2021-03-22 2022-09-02 华熙生物科技股份有限公司 一种交联透明质酸凝胶粗品及其制备方法
US20240352158A1 (en) * 2021-10-15 2024-10-24 Prohibix Llc Crosslinked hyaluronic acid precipitates
CN114404355B (zh) * 2021-12-28 2024-05-24 常州药物研究所有限公司 透明质酸钠凝胶及其制备方法、应用
EP4473021A1 (en) 2022-02-01 2024-12-11 Galderma Holding SA Methods of producing crosslinked hyaluronic acid hydrogels
CN114894789B (zh) * 2022-06-28 2025-08-15 华熙生物科技股份有限公司 一种透明质酸类物质指示剂组合物及其在快速检测透明质酸类物质中的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
AU619760B2 (en) 1987-12-10 1992-02-06 Genzyme Biosurgery Corporation Hylan preparation and method of recovery thereof from animal tissues
JPH01197501A (ja) 1988-02-02 1989-08-09 Mitsubishi Acetate Co Ltd 精製サイリウムガムの製造方法
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
GB9902412D0 (en) * 1999-02-03 1999-03-24 Fermentech Med Ltd Process
TW574301B (en) * 2001-05-02 2004-02-01 Ind Tech Res Inst Manufacturing method of epoxide crosslinked polysaccharides matrix
DE10223310A1 (de) * 2002-05-24 2003-12-11 Biotronik Mess & Therapieg Verfahren zum Beschichten von Implantaten mit einer Polysaccharid-Lage
TWI251596B (en) * 2002-12-31 2006-03-21 Ind Tech Res Inst Method for producing a double-crosslinked hyaluronate material
US7323425B2 (en) * 2004-08-27 2008-01-29 Stony Brook Technology And Applied Research Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom
WO2006051950A1 (ja) 2004-11-15 2006-05-18 Shiseido Co., Ltd. 架橋ヒアルロン酸ゲルの製造方法
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
KR101250846B1 (ko) * 2005-07-04 2013-04-05 주식회사 엘지생명과학 히알루론산 가교물의 제조방법
FR2908415B1 (fr) * 2006-11-10 2009-01-23 Abr Dev Sarl Acide hyaluronique reticule et son procede de preparation
KR20080062092A (ko) * 2006-12-29 2008-07-03 주식회사 핸슨바이오텍 세포전달체로서의 히알루론산 유도체 및 이의 제조 방법
CN101313915B (zh) * 2007-05-30 2011-04-20 北京泰克美科技有限公司 透明质酸及其盐、交联透明质酸及其盐在制备治疗或预防海泡伤药物中的应用
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
FR2920786B1 (fr) * 2007-09-07 2010-09-10 Univ Claude Bernard Lyon Fibres creuses, notamment multi membranaires, leur procede de preparation par filage et dispositif pour la mise en oeuvre dudit procede
CN101821294B (zh) * 2007-09-28 2012-10-31 株式会社资生堂 溶胀性交联透明质酸粉末及其制造方法
ITMI20072416A1 (it) 2007-12-21 2009-06-22 Sigea Srl Derivati polisaccaridici dell'acido lipoico, loro preparazione ed uso come dermocosmetici e presidi medicali
WO2010115081A2 (en) * 2009-04-02 2010-10-07 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US8790702B2 (en) * 2009-07-30 2014-07-29 Carbylan Therapeutics, Inc. Modified hyaluronic acid polymer compositions and related methods
CA2815141A1 (en) * 2010-10-20 2012-04-26 Tautona Group Lp Threads of cross-linked hyaluronic acid and methods of preparation and use thereof
CZ20101001A3 (cs) * 2010-12-31 2012-02-08 Cpn S.R.O. Hyaluronová vlákna, zpusob jejich prípravy a použití
CN102552974A (zh) * 2012-02-17 2012-07-11 上海白衣缘生物工程有限公司 皮肤注射填充用凝胶组合物及其制备
CN102660040B (zh) * 2012-05-03 2014-03-12 杭州协合医疗用品有限公司 一种透明质酸钠凝胶的制备方法
CN102731801B (zh) * 2012-07-13 2013-12-25 常州药物研究所有限公司 外科整形用交联透明质酸钠凝胶及其制备方法
CN102863631B (zh) * 2012-09-29 2013-11-13 杭州嘉伟生物制品有限公司 外科整形用组织填充剂交联透明质酸钠凝胶及其制备方法

Also Published As

Publication number Publication date
WO2014206500A1 (en) 2014-12-31
AU2013396752A1 (en) 2016-02-18
US10982016B2 (en) 2021-04-20
EP3617236B1 (en) 2024-07-31
CN105473622B (zh) 2019-01-29
CA2916119A1 (en) 2014-12-31
KR20160027095A (ko) 2016-03-09
EP3013865B1 (en) 2019-10-23
US11702484B2 (en) 2023-07-18
CN105473622A (zh) 2016-04-06
RU2640865C2 (ru) 2018-01-12
JP6434003B2 (ja) 2018-12-05
US20200247913A1 (en) 2020-08-06
JP2016524016A (ja) 2016-08-12
AU2013396752B2 (en) 2018-11-08
US20210214468A1 (en) 2021-07-15
US20180362670A1 (en) 2018-12-20
CN109734825B (zh) 2022-01-28
US20160145357A1 (en) 2016-05-26
MX2015017526A (es) 2016-08-05
BR112015031589A2 (pt) 2017-07-25
HK1224314A1 (en) 2017-08-18
RU2016101734A (ru) 2017-08-02
EP3617236A1 (en) 2020-03-04
US10077321B2 (en) 2018-09-18
EP3013865A1 (en) 2016-05-04
KR102048395B1 (ko) 2019-11-25
CN109734825A (zh) 2019-05-10

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