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ES2012809B3 - Derivados del taxol, su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Derivados del taxol, su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2012809B3
ES2012809B3 ES87401668T ES87401668T ES2012809B3 ES 2012809 B3 ES2012809 B3 ES 2012809B3 ES 87401668 T ES87401668 T ES 87401668T ES 87401668 T ES87401668 T ES 87401668T ES 2012809 B3 ES2012809 B3 ES 2012809B3
Authority
ES
Spain
Prior art keywords
taxol
derivatives
contain
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87401668T
Other languages
English (en)
Inventor
Michel Colin
Daniel Guenard
Francoise Gueritte-Voegelein
Pierre Potier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9337506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2012809(B3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of ES2012809B3 publication Critical patent/ES2012809B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES87401668T 1986-07-17 1987-07-16 Derivados del taxol, su preparacion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2012809B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8610400A FR2601675B1 (fr) 1986-07-17 1986-07-17 Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2012809B3 true ES2012809B3 (es) 1990-04-16

Family

ID=9337506

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87401668T Expired - Lifetime ES2012809B3 (es) 1986-07-17 1987-07-16 Derivados del taxol, su preparacion y composiciones farmaceuticas que los contienen.

Country Status (15)

Country Link
US (1) US4814470A (es)
EP (1) EP0253738B1 (es)
JP (1) JPH0651689B2 (es)
KR (1) KR950006153B1 (es)
AT (1) ATE49962T1 (es)
AU (1) AU591309B2 (es)
CA (1) CA1278304C (es)
DE (1) DE3761562D1 (es)
ES (1) ES2012809B3 (es)
FR (1) FR2601675B1 (es)
GR (1) GR3000287T3 (es)
LU (1) LU88712I2 (es)
MX (1) MX9203385A (es)
NL (1) NL960002I2 (es)
ZA (1) ZA875179B (es)

Families Citing this family (351)

* Cited by examiner, † Cited by third party
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USRE34277E (en) * 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
MY110249A (en) * 1989-05-31 1998-03-31 Univ Florida State Method for preparation of taxol using beta lactam
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
FR2651226B1 (fr) * 1989-08-23 1993-01-08 Centre Nat Rech Scient Procede pour la preparation enantioselective de derives de la phenylisoserine.
IL95436A (en) * 1989-08-23 1996-07-23 Centre Nat Rech Scient Method for the preparation of phenzlisoserine derivatives
US5304670A (en) * 1989-08-23 1994-04-19 Centre National De La Recherche Scientifique Process for the enantioselective preparation of phenylisoserine derivatives
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5475120A (en) * 1990-11-02 1995-12-12 University Of Florida Method for the isolation and purification of taxol and its natural analogues
US5380916A (en) * 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
FR2669631B1 (fr) * 1990-11-23 1994-09-09 Rhone Poulenc Rorer Sa Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.
AU1888792A (en) * 1991-04-19 1992-11-17 University Of Mississippi, The Methods and compositions for isolating taxanes
US6150398A (en) * 1991-05-08 2000-11-21 The United States Of America As Represented By The Department Of Health And Human Services Methods for the treatment of cancer
CA2072400C (en) * 1991-07-05 2003-08-19 Jayaprakash B. Nair Supercritical extraction of taxanes
US5698582A (en) * 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
US5750561A (en) * 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
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FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
FR2679230B1 (fr) * 1991-07-16 1993-11-19 Rhone Poulenc Rorer Sa Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent.
US7074945B2 (en) * 1991-09-23 2006-07-11 Florida State University Metal alkoxide taxane derivatives
DE69228756T2 (de) * 1991-09-23 1999-10-07 The Florida State University, Tallahassee Darstellung von substituierten isoserinestern unter verwendung von metallalkoxiden und beta-lactams
US5430160A (en) * 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US5654447A (en) * 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5990325A (en) * 1993-03-05 1999-11-23 Florida State University Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
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US6005138A (en) * 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
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US6028205A (en) * 1991-09-23 2000-02-22 Florida State University C2 tricyclic taxanes
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
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US5274124A (en) * 1991-09-23 1993-12-28 Florida State University Metal alkoxides
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US6011056A (en) 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US5283253A (en) * 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5399726A (en) * 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
CA2087359A1 (en) * 1992-01-15 1993-07-16 Ramesh N. Patel Enzymatic processes for resolution of enantiomeric mixtures of compoundsuseful as intermediates in the preparation of taxanes
US6080777A (en) * 1992-01-31 2000-06-27 The Trustees Of Columbia University In The City Of New York Taxol as a radiation sensitizer
WO1993014787A1 (en) * 1992-01-31 1993-08-05 The Trustees Of Columbia University In The City Of New York Taxol as a radiation sensitizer
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US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
US5445809A (en) * 1992-03-03 1995-08-29 Research And Development Institute At Montana State University Production of taxol from the yew tree
US5451392A (en) * 1992-03-03 1995-09-19 The Research And Development Institute At Montana State University Production of taxol
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JPS6330479A (ja) 1988-02-09
FR2601675A1 (fr) 1988-01-22
ATE49962T1 (de) 1990-02-15
NL960002I2 (nl) 1996-11-01
EP0253738B1 (fr) 1990-01-31
KR880001625A (ko) 1988-04-25
CA1278304C (fr) 1990-12-27
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MX9203385A (es) 1992-07-01
US4814470A (en) 1989-03-21
AU591309B2 (en) 1989-11-30
FR2601675B1 (fr) 1988-09-23
ZA875179B (en) 1988-03-30
JPH0651689B2 (ja) 1994-07-06
EP0253738A1 (fr) 1988-01-20
LU88712I2 (fr) 1996-08-23
KR950006153B1 (ko) 1995-06-09
AU7567787A (en) 1988-01-21
GR3000287T3 (en) 1991-03-15

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