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ES2061728T3 - Derivados de alcohol polivinilico, que contienen unidades pendientes de productos de reaccion de monomeros vinilicos enlazadas a traves de grupos eter y lentes de contacto de tipo hidrogel producidas a partir de tales derivados. - Google Patents

Derivados de alcohol polivinilico, que contienen unidades pendientes de productos de reaccion de monomeros vinilicos enlazadas a traves de grupos eter y lentes de contacto de tipo hidrogel producidas a partir de tales derivados.

Info

Publication number
ES2061728T3
ES2061728T3 ES88810845T ES88810845T ES2061728T3 ES 2061728 T3 ES2061728 T3 ES 2061728T3 ES 88810845 T ES88810845 T ES 88810845T ES 88810845 T ES88810845 T ES 88810845T ES 2061728 T3 ES2061728 T3 ES 2061728T3
Authority
ES
Spain
Prior art keywords
derivatives
hydrogen
polyvinyl alcohol
eter
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88810845T
Other languages
English (en)
Inventor
Merrill Goldenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2061728T3 publication Critical patent/ES2061728T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
    • C08F290/12—Polymers provided for in subclasses C08C or C08F

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Eyeglasses (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Materials For Medical Uses (AREA)
  • Colloid Chemistry (AREA)

Abstract

UNA LENTE DE CONTACTO DE UN POLIMERO ENTRECRUZADO, INSOLUBLE EN DISOLVENTES APROTICOS ORGANICOS, PRACTICAMENTE TRANSPARENTE DE UN DERIVADO DE UN ALCOHOL POLIVINILICO, QUE TIENE UN PESO MOLECULAR MEDIO DE POR LO MENOS 2000 APROXIMADAMENTE, QUE CONTIENE UNA CANTIDAD EFECTIVA ENTRE 0,1 Y 90 % APROXIMADAMENTE, EN BASE AL NUMERO DE GRUPOS HIDROXILO SOBRE DICHO ALCOHOL POLIVINILICO, DE UN PRODUCTO DE REACCION DE ADICION ENTRECRUZADA DE UNIDADES DE FORMULA (I), EN PRESENCIA O AUSENCIA DE UN MONOMERO VINILICO POLIMERIZABLE, DONDE R1 ES UN GRUPO DIVALENTE ALIFATICO, CICLOALIFATICO, ARILO, ARALQUILO O ALQUILARILO; A ES -O-, -NH- O -NHCON(R")-, DONDE R" ES HIDROGENO O ALQUILO INFERIOR Y A'' ES UN ENLACE DIRECTO; O A ES UN ENLACE DIRECTO Y A'' ES -O- O -O-CH2-; R2 ES HIDROGENO O METILO O -COOR4, DONDE R4 ES HIDROGENO O ALQUILO INFERIOR; CON LA PROVISION DE QUE SI R2 ES METILO, R3 ES HIDROGENO; Y DONDE EL MONOMERO VINILICO POLIMERIZABLE, SI ESTA PRESENTE, ES HIDROFOBO, O ES UNA MEZCLA DE MONOMEROS VINILICOS HIDROFOBOS O HIDROFILOS, MEZCLA EN LA QUE POR LO MENOS EL 50 % DE LOS MONOMEROS VINILICOS SON HIDROFOBOS.
ES88810845T 1987-12-16 1988-12-07 Derivados de alcohol polivinilico, que contienen unidades pendientes de productos de reaccion de monomeros vinilicos enlazadas a traves de grupos eter y lentes de contacto de tipo hidrogel producidas a partir de tales derivados. Expired - Lifetime ES2061728T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/133,575 US4978713A (en) 1987-12-16 1987-12-16 Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom

Publications (1)

Publication Number Publication Date
ES2061728T3 true ES2061728T3 (es) 1994-12-16

Family

ID=22459286

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88810845T Expired - Lifetime ES2061728T3 (es) 1987-12-16 1988-12-07 Derivados de alcohol polivinilico, que contienen unidades pendientes de productos de reaccion de monomeros vinilicos enlazadas a traves de grupos eter y lentes de contacto de tipo hidrogel producidas a partir de tales derivados.

Country Status (12)

Country Link
US (1) US4978713A (es)
EP (1) EP0321403B1 (es)
JP (1) JP2825130B2 (es)
AT (1) ATE100216T1 (es)
AU (1) AU618042B2 (es)
CA (1) CA1330674C (es)
DE (1) DE3887116T2 (es)
DK (1) DK698388A (es)
ES (1) ES2061728T3 (es)
IE (1) IE62438B1 (es)
IL (1) IL88652A0 (es)
PT (2) PT89211B (es)

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EP1874528B9 (en) * 2005-04-29 2009-09-23 Novartis AG Lens molds with coating and process for making a contact lens
US20070185014A1 (en) * 2006-02-09 2007-08-09 The Schepens Eye Research Institute, Inc. Methods and compositions for modulating conjunctival goblet cells
JP5238514B2 (ja) 2006-02-10 2013-07-17 バイオコンパティブルズ ユーケー リミテッド 親水性ポリマー送達システムへの疎水性薬剤の負荷
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Also Published As

Publication number Publication date
IL88652A0 (en) 1989-07-31
CA1330674C (en) 1994-07-12
DK698388A (da) 1989-06-17
DE3887116D1 (de) 1994-02-24
DK698388D0 (da) 1988-12-15
AU618042B2 (en) 1991-12-12
AU2684588A (en) 1989-06-22
ATE100216T1 (de) 1994-01-15
DE3887116T2 (de) 1994-06-16
JP2825130B2 (ja) 1998-11-18
EP0321403A3 (en) 1990-12-27
EP0321403B1 (en) 1994-01-12
PT89211B (pt) 1993-07-30
IE883746L (en) 1989-06-16
JPH01250923A (ja) 1989-10-05
EP0321403A2 (en) 1989-06-21
US4978713A (en) 1990-12-18
PT90559A (pt) 1989-11-30
IE62438B1 (en) 1995-02-08
PT89211A (pt) 1989-12-29

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