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EP2210667B1 - Dispositif de dosage avec éjecteur de pointe - Google Patents

Dispositif de dosage avec éjecteur de pointe Download PDF

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Publication number
EP2210667B1
EP2210667B1 EP09000662.8A EP09000662A EP2210667B1 EP 2210667 B1 EP2210667 B1 EP 2210667B1 EP 09000662 A EP09000662 A EP 09000662A EP 2210667 B1 EP2210667 B1 EP 2210667B1
Authority
EP
European Patent Office
Prior art keywords
stop
metering device
ring
counter
transmitting mechanism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP09000662.8A
Other languages
German (de)
English (en)
Other versions
EP2210667A1 (fr
Inventor
Herbert Belgardt
Burkhardt Reichmuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf SE filed Critical Eppendorf SE
Priority to EP09000662.8A priority Critical patent/EP2210667B1/fr
Priority to CN201010005412.6A priority patent/CN101819054B/zh
Publication of EP2210667A1 publication Critical patent/EP2210667A1/fr
Application granted granted Critical
Publication of EP2210667B1 publication Critical patent/EP2210667B1/fr
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Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects

Definitions

  • the invention relates to a metering device for quantities of liquid, in particular in the range of 100 nl to several 100 ml, with at least one seat for releasably securing a pipette tip and a discharge device for releasing the pipette tip of the seat.
  • Dosing devices are mainly used in the laboratory for dosing liquids.
  • the liquids are taken up in pipette tips and discharged from it.
  • Pipette tips are small tubes with an opening at the bottom and an opening at the top. The lower opening is usually smaller than the upper opening.
  • the displacement device is usually a cylinder with a piston displaceable therein.
  • the piston and cylinder are integrated into the metering device and communicate with it through the top opening of the pipette tip so that the metering of the fluid is communicated via an air cushion.
  • direct displacement systems the piston and cylinder are integrated into the tip and act directly on the aspirated fluid.
  • Such pipette tips are also referred to as syringes.
  • Dosing devices that collect liquid in a single cut and deliver it into a single cut are called pipettes.
  • the pipette tip is detachably connected to the dosing device so that it can be exchanged for a fresh pipette tip after use, thereby avoiding contamination at subsequent dosages.
  • Plastic pipette tips for single use are available at low cost.
  • the metering device has at least one seat for releasably securing one or more pipette tips.
  • the seat is often a conical hub on which a pipette tip is clamped to the upper opening.
  • metering devices having a bore into which a pipette tip can be clamped with the end having the upper opening.
  • the dosing device may include receptacles for an upper portion of the cylinder and a piston rod of the piston, and gripping means for holding the upper portions of the cylinder and piston rod in the receptacles. The attachment can be done without touching the pipette tip by placing the metering device with its seat on the pipette tip, which is available in a holder.
  • the discharge device on a discharge bar, which is connected below with an ejector, which is designed for example as a discharge sleeve or as a discharge plate.
  • the ejector is assigned to the upper edge region of a pipette tip attached to the metering device.
  • a coil spring pushes the discharge rod into a starting position in which it bears against an abutment stop, which is firmly connected to the dosing device housing.
  • the discharge bar is connected at the top with a discharge button. By pressing the ejection button can against the action of the coil spring the With its ejector, the ejection device is pressed against the upper edge of the pipette tip or syringe so that it is released from the seat.
  • the eject button connected via a snap connection with the discharge rod.
  • the stopper is a snap ring made of steel, which is mounted in an annular groove of the discharge bar.
  • the eject button must be pressed so that the lower end of the ejector rod protrudes from the pipette housing.
  • the assembly of the small snap ring by means of a special tool is difficult. If the release button is released during operation, the coil spring presses the ejection device into its starting position so that the snap ring strikes against the counterstop.
  • the counter-stop is formed by the edge of a hole in a rigid housing wall, which is interspersed by the discharge rod. Here, a strong pulse is introduced into the discharge device.
  • the ejection button does not accidentally loosen, it is attached by means of a shock-resistant snap on the discharge rod.
  • the ejection button When disassembling the pipette for maintenance or repair, the ejection button must be drilled to release the snapping with a tool. The drilled ejection button must be replaced by a new ejection button.
  • the WO 96/37302 A1 describes a pipette with a dropper device for pipette tips, which has a discharge bar with a discharge button at the top and a discharge sleeve at the bottom.
  • the discharge rod is pressed by a spring arranged between discharge button and housing in an initial position in which presses a stop in the form of a release rod arranged snap ring against a wall of the rigid housing. After dropping the spring moves the discharge rod back to the starting position, whereby the snap ring strikes hard against the housing.
  • the EP 1 557 222 A2 describes a pipetting device with a lug on which a pipette tip can be clamped.
  • the approach is supported by a spring in the housing.
  • an approach is displaced against the action of the spring until the upper edge of the pipette tip meets a stop at the lower end of a dropper, which is supported on a boundary in the housing.
  • an actuating button is pressed, which displaces against the action of a coil spring a discharge rod, which is pressed with its lower end in a bore at the top of the ejector.
  • the operating button is relieved. After that, the coil spring pushes back the ejector rod, so that the ejector hits the top hard on the boundary.
  • the WO 01/57490 A1 describes a pipette with a discharge device, which has a spring store.
  • the spring accumulator is tensioned by attaching a pipette tip.
  • a hard projection of the discharge rod meets a hard counter-stop in the housing.
  • the unloading of the spring accumulator is controlled by operating the Abwerfknopfes. At the end of the throw-off movement of the ejector hits a hard stop the release rod on the counter-attack.
  • the US 5,104,624 describes a pipette with a ejector, which is biased by a coil spring in an initial position in which abuts a hard stop of the ejector to a hard counter-stop in the housing.
  • the present invention seeks to provide a metering device with a discharge device available, which is easier to assemble and disassemble.
  • the metering device has a base body, which is a supporting structure for further components of the metering device.
  • the main body is for example a housing.
  • At least one seat for releasably securing a pipette tip is arranged on the base body.
  • a single seat is available.
  • the metering device has several seats, for example, eight.
  • the seat for releasably securing a pipette tip can be designed as a conical approach for attaching a pipette tip or as a hole for insertion of a pipette tip.
  • the seat may include receptacles for upper portions of the cylinder and piston associated with gripping means for holding the syringe to the housing.
  • the discharge device On the main body is a discharge device with a relative to the seat movable ejector available.
  • the ejector is for example a discharge sleeve or a discharge plate.
  • a Einkanaldosiervorraum example, with a discharge sleeve and a Mehrkanaldosiervorraum is provided for example with a discharge plate, the discharge plate is also assigned to several seats.
  • the discharge device has a with the
  • the ejector can be detachably or non-detachably operatively connected to the transmission mechanism.
  • ejector and transfer mechanism can be releasably or non-releasably firmly connected to each other, for example, by a clamp connection or by a one-piece design when transmission mechanism and ejector are made as a part of a material.
  • the drive means may be manual drive means or motor drive means such as electric motors.
  • Manual drive means may comprise a release button operatively connected to the transfer mechanism and motor drive means having an electrical linear drive connected to the transfer mechanism.
  • the transmission mechanism is also provided with a stop.
  • a counter stop On the main body there is a counter stop, which cooperates with the stop to the movement of the ejector upwards, d. H. from the seat, to limit away.
  • a restoring means acting on the main body and the ejection device presses the ejection device with the stop against the counter-stop if the transmission mechanism is not driven by the drive means.
  • the snap ring and the cooperating housing wall are rigid perpendicular to their stop surfaces, so that the snap ring is abruptly braked when hitting the housing wall.
  • the stop and / or the counter-stop is at least in the direction perpendicular to the respective stop surface elastically deformable, so that stop and / or counter-stop deform elastically during the meeting.
  • the stop and / or counter-stop may consist of a material which is in particular perpendicular to the stop surface.
  • the invention relates to embodiments in which the stopper is elastic perpendicular to its abutment surface and the counter-abutment is rigid, the counter-stopper is perpendicular to its abutment surface elastic and the abutment is rigid and both the abutment and the abutment stop are perpendicular to their abutment surfaces.
  • the stop and / or counter-stop can be elastic only perpendicular to its stop surface or in the transverse direction or in any direction. The latter is in particular after execution of the stop and / or counter-attack of an elastic material of the case.
  • the perpendicular to the stop surface elastic stop and / or counter-stop can be easily assembled and disassembled.
  • the stop and / or counter-stop weakens the shock that occurs after an actuation of the ejection device when the return means moves the ejection device with the stop against the counter-stop.
  • the shock is not suddenly effective when hitting a hard stop on a hard counter-attack, but delayed by the perpendicular to the stop surface elastic stop and / or counter-stop and thus weakened.
  • Due to this weakening of the shock a connection between the drive means and the discharge rod can be designed as a detachable latching connection. This is relatively easy to disassemble without being destroyed, so that it is then re-assembled.
  • the weakening of the impulse upon impact of the stop on the counter stop prevents unintentional release of the catch. Through targeted use of force, however, it is possible to separate the locking connection. As a result, the disassembly of the metering device is facilitated in their individual parts, especially during maintenance and repair.
  • Elastic deformable material has damping properties, so it absorbs part of the energy of the impact.
  • the stop and / or counter-stop can be wholly or partly made of a selected elastically deformable material that dampens particularly well.
  • the materials used have a resilience according to DIN 53 512, which is less than 25%.
  • Particularly preferred materials have a rebound resilience that is less than 10%. Even more suitable are materials with a resilience of less than 5%.
  • the elastically deformable material is rubber-elastic.
  • the stop and / or counter-stop consists of an elastomer (eg rubber or silicone rubber) or a thermoplastic elastomer.
  • the stop and / or counter-stop is made of an autoclavable material. With appropriate design of the other components of the metering device, this is a total of autoclavable.
  • the stop and / or counter-stop is made of a fluoroelastomer (eg Viton® from DuPont), preferably with a resilience of about 6.4%. Particularly temperature-resistant and therefore suitable for autoclaving fluoroelastomers are available.
  • fluoroelastomers are particularly suitable as elastically deformable material: perfluorinated rubber (FFPM), butyl rubber (HR) and chlorosulfonated polyethylene (CSM).
  • the stop and / or counter-stop can have different geometries. If the stop and / or counter-stop is made of a material which is elastically deformable at least in the direction perpendicular to its abutment surface, the stop may be formed, for example, by a pin made of the same material which is passed through a bore of a rod section of the transfer mechanism and laterally projecting from the rod portion. In which Stop can also be acting on the rod portion protruding knobs of the elastic material. Further, this may be a laterally projecting portion of the rod portion, which consists entirely of the elastic material.
  • the counter-stop may be a housing wall made entirely of the elastic material with a bore through which a rod portion of the transmission mechanism is passed.
  • the stop is a seated on a rod portion of the transmission mechanism ring and / or the counter-stop a rod portion of the transmission mechanism enclosing ring.
  • This embodiment can be realized particularly inexpensive.
  • the execution of the stop and / or counter-attack as a ring facilitates assembly and disassembly, since the simply axially mounted on a rod portion of the transmission mechanism and removed from this and / or inserted into a bore of a housing and removed from this.
  • the ring can be configured differently.
  • the invention particularly relates to circular cylindrical configurations of the ring.
  • the ring is a torus.
  • the toroidal ring has a circular cylindrical cross-section. Pushing on a discharge rod and the removal of the discharge rod is facilitated in a toroidal ring by the relatively low friction.
  • the toroidal ring may in particular be an O-ring that can otherwise be used as a sealing element.
  • the ring is elastically expanded placed on the rod portion so that it is stuck due to its elastic bias on the rod portion.
  • the ring may consist only partially of an elastically deformable material.
  • the elastically deformable material in a receptacle for. B. off Be received metal, so that forms the elastic deformable material a stop surface at the meeting of stop and counter-stop.
  • the ring is seated in an annular groove of the rod portion, wherein the ring protrudes outside over the lateral surface of the rod portion.
  • the annular groove of the ring is fixed in position on the rod section.
  • the outside in front of the peripheral region of the ring forms a stop surface, which cooperates with the counter-stop.
  • the ring can be arranged without elastic bias in the annular groove. Then it is only elastically expanded when brushing on the rod section until it snaps into the annular groove. Conversely, it is elastically expanded during stripping until it is released from the rod section.
  • the ring sits under elastic bias on the rod portion.
  • This embodiment is possible in embodiments in which the ring sits on a smooth rod section. Further, it is possible in embodiments in which the ring is seated in an annular groove or on a rod portion having at least one projection for laterally supporting the ring in a certain position.
  • the ring is arranged in a below the counter-attack from the outside accessible lower end portion of the rod portion having a releasable connection with the ejector, which is preferably guided movably on the base body.
  • the detachable connection of the rod portion with the ejector is for example a plug or clamp connection. It can be made in particular by the fact that the lower end of the rod portion is pressed into a bore of the ejector. At least after releasing the ejector from the rod portion is the lower End section accessible from the outside, so that the ring can be removed from the rod section.
  • the transmission mechanism can be executed differently. You can, for example, one of the in the EP 0 992 288 B1 Be described transmission that transmits the axial drive movement of the drive device in an axial movement of the ejection element.
  • the transmission mechanism is a discharge rod.
  • the discharge rod may consist of a single rod portion which may be wholly or partially rectilinear and wholly or partially curved and / or bent.
  • the discharge rod may have a plurality of rod sections.
  • the invention relates to embodiments in which the discharge bar has parallel bar sections.
  • the discharge bar can be designed with different cross-sections (eg rectangular, circular, cylindrical, hollow-cylindrical), wherein along the discharge bar everywhere the same cross-sectional shape with the same or different dimensions or different cross-sectional shapes can be present.
  • the upper end of the transmission mechanism is attached via a releasable latching connection to a drive means.
  • the releasable latching connection comprises a latching hook and an undercut for the latching hook
  • the locking surfaces have an angle of 10 ° to 50 °.
  • locking angle of 15 ° to 45 ° are used, particularly preferably locking angle of 25 ° to 35 °.
  • a latching connection with locking surfaces with these angles holds operational loads, as they occur in the muted impact of the transmission mechanism with the stop on the counter-stop. Under increased use of force, however, this locking connection is solvable. This is especially true in execution of the parts of the locking connection of a plastic.
  • the angle of the locking surfaces refers to their inclination to an axis, in the direction of which the load of the locking connection takes place during operation.
  • the locking connection can be solved with the aid of a tool.
  • the drive means is a discharge button with a top wall with a standing from the bottom in front of locking hooks with the locking surface at the bottom.
  • the ejection button on the periphery has a diaphragm which laterally covers a free space between the top wall and an upper region of a housing of the metering device.
  • the locking connection can be achieved by inserting a strip-shaped tool through a gap between the ejection button and the housing.
  • the ejection button has two dome protruding from the underside of the top wall, each having a bore, and the ejector rod has two pins at the top end which are inserted into the bore of the domes.
  • the two pins project from an upper traverse of the discharge rod, below the cross member has two substantially parallel bar sections, which are interconnected below by a lower cross member, and protrudes from the bottom of the lower cross member, a lower bar section, the wearing the ring of elastically deformable material.
  • the two parallel bar sections can accommodate, for example, an electric drive motor of an electrically driven metering device between them and thus favor a space-saving design of the metering device.
  • Restoring means are means by which two objects are held in at least one direction in a defined position to each other and ensure that the two objects get back into the same defined position when they were brought by an external influence from the position, as soon as this Influence is no longer present.
  • the return means are spring means (eg a coil spring sitting on a discharge bar or a gas spring).
  • the return means additionally comprise hydraulic means (eg compressive fluids) and / or pneumatic means and / or magnetically acting means (eg with repelling magnets, one fixed to the housing and the other firmly connected to the transfer mechanism) , Used as a return means Federstoff used as a helical spring, so should your spring constant D according to the Hooke's law in particular smaller than 0.2 N / mm, preferably even less than 0.1 N / mm and more preferably less than 0.05 N / mm.
  • hydraulic means eg compressive fluids
  • pneumatic means eg with repelling magnets, one fixed to the housing and the other firmly connected to the transfer mechanism
  • the metering device is a manual and / or an electrical metering device.
  • a displacer or displacer eg, a piston in a cylinder
  • the displacement element is driven by means of an electric drive motor.
  • the dosages can be triggered or stopped manually.
  • a program-controlled operation is also possible.
  • the dosing device is a stationary dosing device and / or a manual dosing device.
  • the metering device is a pipette and / or a dispenser. It can be designed as a pipette with a constant or adjustable dosing volume or as a dispenser with a constant or adjustable dispensing volume. Also combinations of pipette and dispenser are possible.
  • a preferred embodiment is a manually or electrically driven handheld pipette or hand dispenser.
  • the invention relates to a method for mounting a discharge device on a metering device, wherein a transmission mechanism of the discharge device is inserted into a housing of the metering device, so that a rod portion of the transfer mechanism protrudes from a hole of the housing and a ring, which is an elastically deformable material has, is pushed onto the protruding rod portion.
  • the ring may consist partially or entirely of the elastically deformable material.
  • the ring is in pushed an annular groove formed on the rod portion. The sliding of the ring is possible to simplify the production step without consuming special tools.
  • a drive means with a releasable connection in particular latching connection attached.
  • the latching connection comprises a latching hook and an undercut for the latching hook.
  • top and “bottom” and “top” and “bottom” and “bottom end” and “top” refer to the preferred position of the pipette in operation, in which the pipette is vertically aligned and a Pipette tip connected to the pipette is arranged below the pipette.
  • Fig. 1 an electrical pipette is shown in side view, which is driven by an electric drive motor. It was in Fig. 1 in the field of Discard the pipette the housing omitted to represent the ejector.
  • a manual pipette is shown in side view, which can be operated by hand. It was in Fig. 2 in the area of the actual pipette, ie where the actual pipetting takes place, the housing omitted to show the essential components of a pipette.
  • Fig. 1 and 2 has a pipette according to the invention 1 designed as a handle pipette housing 2 with an upper housing part 3 and a lower housing part 4.
  • the upper housing part 3 has below bottom connecting means 5 and the lower housing part 4 has top connecting means 6, are interconnected by the upper housing part 3 and lower housing part 4.
  • the connecting means 5, 6 are designed, for example, as a screw or cancelable latching connection.
  • the lower housing part 4 has a housing shaft 7, which has at the lower end a seat 8 in the form of a conical Aufsteckzapfens.
  • a pipette tip 9 made of plastic has a tubular body 10 with an upper opening 11 and a lower opening 12.
  • the body 10 is conically designed with a small cone angle.
  • the pipette tip 9 is attached to the upper opening 11 on the seat 8, so that it clamps, but can be pushed off the seat 8.
  • an actuating knob 13 which is fixedly connected to a lifting rod 14, which is extends to the lower end of the upper housing part 3.
  • the lifting rod 14 carries on the circumference of an annular bead 15th
  • an adjusting sleeve 16 protrudes upwards out of the upper housing part for setting the metering quantity, which surrounds the actuating knob 13.
  • the adjusting sleeve 16 is connected via grooves on the inner circumference and engaging therein driver via a gear rotatably and axially relatively movable with a spindle 18 for adjusting the stroke of the lifting rod 14.
  • the spindle 18 has a contact surface 19 for the annular bead 15, which is axially displaceable to the lifting rod 14 to limit their stroke.
  • a piston 21 is slidably disposed in a cylinder 22.
  • the piston 21 is connected via a piston rod 23 with a pressure plate 24.
  • the cylinder 22 is connected via a channel 26 to an opening 27 in the lower end of the seat 8.
  • a discharge device 28 is arranged on the pipette housing 2 of the pipette 1 of Fig. 1 and 2 .
  • This has in the upper housing part 3 a discharge bar 29, which is connected at the top with a discharge button 30.
  • the discharge rod 29 has two substantially parallel bar sections 29.1, 29.2, which are connected to each other at the top by an upper cross member 31.1 and below by a lower cross member 31.2. From the upper cross member 31.1 are two pins 32.1, 32.2 high, which are parallel to the extend two rod sections 29.1, 29.2. Furthermore, the upper cross-member 31.1 has an undercut 33 with a detent surface 34 which is directed approximately at 30 ° to the axes of the rod sections 29.1, 29.2.
  • the ejection button 30 has a top wall 37 with a locking hook 38 projecting from the underside, which has a further latching surface 39 at the lower end.
  • the locking surface 39 has an angle with respect to a perpendicular to the latching hook of about 30 °, which corresponds to the angle of the undercut 33 of the discharge rod 29.
  • the ejection button 30 has an aperture 42 at an edge portion of its top wall 37.
  • the discharge rod 29 is arranged with the parallel rod sections 29.1, 29.2 in a guide channel 43 of the upper housing part 3.
  • the ejection button 30 is locked with the discharge rod 29.
  • the lower bar section 29.3 is passed through a hole 44 in a cross section of the upper housing part 3 partially obstructing bottom wall 45.
  • a coil spring 46 On the lower rod portion 29.3 is a coil spring 46, e.g. with a spring constant D of 0.13 N / mm out, which is supported one end on the lower cross member 31.2 and other ends on the bottom wall 45.
  • a toroidal ring 47 made of an elastically deformable material, such as. Viton® from DuPont, in particular with a rebound resilience of 6.4%.
  • the ring 47 protrudes slightly beyond the circumference of the rod part 29.3.
  • a discharge sleeve 48 is guided, which has a lateral projection 49 at the top, which has a further bore 50.
  • a metered amount can be selected.
  • air is forced out of the cylinder 22 and the pipette tip 9. Then, the pipette tip 9 can be immersed with the lower opening 12 in a liquid.
  • the Actuator knob 13 pushes the piston return spring 25, the piston 22 in the starting position and liquid is sucked into the pipette tip 9.
  • the pipette 1 can be moved with the pipette tip 9 via a receptacle and by pressing the actuating button 13 again a selected amount of liquid from the pipette tip 9 are ejected. Subsequently, the operation knob 13 is relieved and the piston 22 returns to its original position.
  • the used pipette tip 9 is released by pressing the ejection button 30 against the force of the coil spring 46 from the seat 8.
  • the discharge sleeve 48 is displaced along the housing shaft 7 down and pushes with its lower edge 51 against the upper edge 11 of the pipette tip 9, so that it is released from the seat 8.
  • the stop or ring 47 moves away from the counter-stop 52 (cf. 8 and 9 ).
  • the discharge button 30 is released and the discharge device 28 returns to its original position.
  • the ring 47 beats against the counter-stop 52 due to the action of the coil spring 46, wherein the pulse is damped by the elastically deformable material.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Claims (12)

  1. Dispositif de dosage comprenant
    - un corps de base (2),
    - au moins un siège (8) disposé sur le corps de base (2) pour la fixation amovible d'une pointe de pipette (9),
    - un dispositif d'éjection (28) disposé sur le corps de base (2) pour le détachement de la pointe de pipette (9) par rapport au siège (8),
    - lequel présente un éjecteur (48) déplaçable par rapport au siège (8),
    - une mécanique de transfert (29) fonctionnellement reliée à l'éjecteur (48) pour le déplacement de l'éjecteur (48) par rapport au siège (8),
    - un moyen d'entraînement (30) pour l'entraînement de la mécanique de transfert (29), et
    - une butée (47) sur la mécanique de transfert (29),
    - une contre-butée (52) disposée sur le corps de base (2), laquelle est attribuée à la butée (47) et limite le déplacement de la mécanique de transfert (29) vers le haut, et
    - un moyen de rappel (46) s'appliquant d'une part sur le corps de base (2) et d'autre part sur le dispositif d'éjection (28), lequel consiste en un moyen à ressort et presse la butée (47) contre la contre-butée (52) lorsque la mécanique de transfert (29) n'est pas entraînée par le moyen d'entraînement,
    - caractérisé en ce que la butée (47) et/ou la contre-butée (52) sont constituées au moins partiellement d'un élastomère ou d'un élastomère thermoplastique et peuvent se déformer élastiquement, perpendiculairement à leur surface de butée, de telle façon que la butée (47) et/ou la contre-butée (52) interceptent le coup, lorsque le moyen de rappel (46) déplace le dispositif d'éjection (28) avec la butée (47) contre la contre-butée (52).
  2. Dispositif de dosage selon la revendication 1, dans lequel la butée (47) et/ou la contre-butée (52) présentent un matériau élastiquement déformable, dont l'élasticité de rebond est inférieure à 25 %.
  3. Dispositif de dosage selon la revendication 1 ou 2, dans lequel la butée (47) et/ou la contre-butée (52) sont constituées d'un matériau autoclavable.
  4. Dispositif de dosage selon l'une des revendications 1 à 3, dans lequel la butée (47) et/ou la contre-butée (52) sont constituées d'un élastomère fluoré.
  5. Dispositif de dosage selon l'une des revendications 1 à 4, dans lequel la butée (47) consiste en un anneau placé sur une section de barre (29.3) de la mécanique de transfert (29) et/ou la contre-butée consiste en un anneau entourant une section de barre (29.3) de la mécanique de transfert (29).
  6. Dispositif de dosage selon la revendication 5, dans lequel l'anneau (47) est un tore.
  7. Dispositif de dosage selon la revendication 5 ou 6, dans lequel l'anneau (47) est placé dans une rainure annulaire (35) de la section de barre (29.3) de la mécanique de transfert (29), l'anneau (47) faisant saillie à l'extérieur au-delà de la surface d'enveloppe de la section de barre (29.3).
  8. Dispositif de dosage selon l'une des revendications 5 à 7, dans lequel l'anneau (47) est placé sur la section de barre (29.3) en étant précontraint élastiquement.
  9. Dispositif de dosage selon l'une des revendications 5 à 8, dans lequel l'anneau (47) est disposé dans une section d'extrémité inférieure de la section de barre (29.3) accessible depuis l'extérieur sous la contre-butée, laquelle présente une liaison amovible avec l'éjecteur (48).
  10. Dispositif de dosage selon l'une des revendications 1 à 8, dans lequel l'éjecteur (48) et la mécanique de transfert (29) sont conçus comme une seule pièce.
  11. Dispositif de dosage selon l'une des revendications 1 à 10, dans lequel la mécanique de transfert est une barre d'éjection (29).
  12. Dispositif de dosage selon l'une des revendications 1 à 11, dans lequel l'extrémité supérieure de la mécanique de transfert (29) est fixée à un moyen d'entraînement (30) par le biais d'un assemblage à encliquetage (34, 39) comportant un crochet d'encliquetage (38) et une contre-dépouille (33) pour le crochet d'encliquetage (38).
EP09000662.8A 2009-01-19 2009-01-19 Dispositif de dosage avec éjecteur de pointe Active EP2210667B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09000662.8A EP2210667B1 (fr) 2009-01-19 2009-01-19 Dispositif de dosage avec éjecteur de pointe
CN201010005412.6A CN101819054B (zh) 2009-01-19 2010-01-19 计量装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09000662.8A EP2210667B1 (fr) 2009-01-19 2009-01-19 Dispositif de dosage avec éjecteur de pointe

Publications (2)

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EP2210667A1 EP2210667A1 (fr) 2010-07-28
EP2210667B1 true EP2210667B1 (fr) 2019-05-08

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EP (1) EP2210667B1 (fr)
CN (1) CN101819054B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012209314B4 (de) 2012-06-01 2015-04-02 Albert-Ludwigs-Universität Freiburg Vorrichtung und Verfahren zur Abgabe oder Aufnahme eines Flüssigkeitsvolumens
CN102698824A (zh) * 2012-06-07 2012-10-03 林昂 一种新型移液器
EP3680016B1 (fr) * 2019-01-08 2021-08-11 Eppendorf AG Pipette destinée à une utilisation avec une pointe de pipette
CN112517098B (zh) * 2020-12-01 2022-05-03 重庆市开州区华兰生物单采血浆有限公司 一种生物医学实验室用延时补压移液器

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104624A (en) * 1989-10-20 1992-04-14 Costar Corporation Pipetter
US5614153A (en) * 1995-05-26 1997-03-25 Rainin Instrument Co., Inc. Pipette tip ejector
DE19845950C1 (de) 1998-10-06 2000-03-23 Eppendorf Geraetebau Netheler Pipettiersystem mit einer Pipettiervorrichtung und mindestens einer daran lösbar befestigten Pipettenspitze
US6532837B1 (en) * 2000-02-03 2003-03-18 Rainin Instrument, Llc Pipette device with tip ejector utilizing stored energy
DE102004003433B4 (de) * 2004-01-21 2006-03-23 Eppendorf Ag Pipettiervorrichtung mit einer Abwurfeinrichtung für Pipettenspitzen
DE102006024051A1 (de) * 2006-05-23 2007-12-06 Eppendorf Ag Elektronische Dosiervorrichtung zum Dosieren von Flüssigkeiten
DE102006037213A1 (de) * 2006-08-09 2008-02-14 Eppendorf Ag Elektronische Dosiervorrichtung zum Dosieren von Flüssigkeiten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
CN101819054A (zh) 2010-09-01
EP2210667A1 (fr) 2010-07-28
CN101819054B (zh) 2015-07-01

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