EE200100559A - Atsetüülsalitsüülhapet ja klopidogreelvesiniksulfaati sisaldav farmatseutiline kompositsioon üksikannusvormis - Google Patents
Atsetüülsalitsüülhapet ja klopidogreelvesiniksulfaati sisaldav farmatseutiline kompositsioon üksikannusvormisInfo
- Publication number
- EE200100559A EE200100559A EEP200100559A EEP200100559A EE200100559A EE 200100559 A EE200100559 A EE 200100559A EE P200100559 A EEP200100559 A EE P200100559A EE P200100559 A EEP200100559 A EE P200100559A EE 200100559 A EE200100559 A EE 200100559A
- Authority
- EE
- Estonia
- Prior art keywords
- pharmaceutical composition
- dosage form
- unit dosage
- hydrogen sulfate
- acetylsalicylic acid
- Prior art date
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title 1
- 229960001138 acetylsalicylic acid Drugs 0.000 title 1
- 229950010477 clopidogrel hydrogen sulphate Drugs 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
- FDEODCTUSIWGLK-UHFFFAOYSA-N hydrogen sulfate;hydron;methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)acetate Chemical compound OS(O)(=O)=O.C1CC=2SC=CC=2CN1C(C(=O)OC)C1=CC=CC=C1Cl FDEODCTUSIWGLK-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9905497A FR2792836B3 (fr) | 1999-04-30 | 1999-04-30 | Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel |
| PCT/FR2000/001086 WO2000066130A1 (fr) | 1999-04-30 | 2000-04-25 | Composition pharmaceutique sous forme unitaire contenant de l'acide acetylsalicylique et de l'hydrogenosulfate de clopidogrel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200100559A true EE200100559A (et) | 2003-02-17 |
Family
ID=9545071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200100559A EE200100559A (et) | 1999-04-30 | 2000-04-25 | Atsetüülsalitsüülhapet ja klopidogreelvesiniksulfaati sisaldav farmatseutiline kompositsioon üksikannusvormis |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1178809A1 (fr) |
| JP (1) | JP2002543137A (fr) |
| KR (1) | KR20020005735A (fr) |
| CN (1) | CN1359294A (fr) |
| AR (1) | AR023789A1 (fr) |
| AU (1) | AU4303600A (fr) |
| BR (1) | BR0010194A (fr) |
| CA (1) | CA2371231A1 (fr) |
| CZ (1) | CZ20013887A3 (fr) |
| EA (1) | EA200100959A1 (fr) |
| EE (1) | EE200100559A (fr) |
| FR (1) | FR2792836B3 (fr) |
| HK (1) | HK1041823A1 (fr) |
| HU (1) | HUP0202329A2 (fr) |
| IL (1) | IL145648A0 (fr) |
| IS (1) | IS6084A (fr) |
| MX (1) | MXPA01011071A (fr) |
| NO (1) | NO20015295L (fr) |
| NZ (1) | NZ514248A (fr) |
| PL (1) | PL351923A1 (fr) |
| SK (1) | SK15542001A3 (fr) |
| TR (1) | TR200103039T2 (fr) |
| UY (1) | UY26131A1 (fr) |
| WO (1) | WO2000066130A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1350511B1 (fr) | 2000-12-25 | 2008-09-10 | Daiichi Sankyo Company, Limited | Compositions medicales contenant de l'aspirine |
| RU2180848C1 (ru) * | 2001-01-30 | 2002-03-27 | Плотников Марк Борисович | Средство с антиагрегантной и гемореологической активностью |
| US6767913B2 (en) | 2001-12-18 | 2004-07-27 | Teva Pharmaceutical Industries Ltd. | Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms |
| US7074928B2 (en) | 2002-01-11 | 2006-07-11 | Teva Pharmaceutical Industries, Ltd. | Polymorphs of clopidogrel hydrogensulfate |
| IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| US6800759B2 (en) | 2002-08-02 | 2004-10-05 | Teva Pharmaceutical Industries Ltd. | Racemization and enantiomer separation of clopidogrel |
| JP4917255B2 (ja) * | 2003-10-16 | 2012-04-18 | 第一三共ヘルスケア株式会社 | サリチル酸類含有経口組成物 |
| WO2005070464A2 (fr) * | 2004-01-21 | 2005-08-04 | Biofarma Ilac Sanayi Ve Ticaret A.S. | Formulation de comprimes de bisulfate de clopidogrel |
| AU2006259606A1 (en) * | 2005-06-13 | 2006-12-28 | Elan Pharma International, Limited | Nanoparticulate clopidogrel and aspirin combination formulations |
| KR20070009851A (ko) * | 2005-07-14 | 2007-01-19 | 씨제이 주식회사 | 클로피도그렐 황산수소염 함유 약학 조성물 |
| CA2618187C (fr) * | 2005-09-21 | 2011-06-21 | Chong Kun Dang Pharmaceutical Corp. | Nouveau complexe de resinate de s-clopidogrel et procede pour le produire |
| KR20070044323A (ko) * | 2005-10-24 | 2007-04-27 | 에스케이케미칼주식회사 | 보관안정성이 개선된 클로피도그렐 황산수소염 함유 경구용제제 |
| US20100145053A1 (en) * | 2006-04-05 | 2010-06-10 | Cadila Healthcare Limited | Modified release clopidogrel formulation |
| EP1900358A1 (fr) * | 2006-09-16 | 2008-03-19 | Cimex Pharma AG | Formulations pharmaceutiques contenant du clopidogrel |
| HUP0600839A3 (en) * | 2006-11-14 | 2008-09-29 | Egis Gyogyszergyar Nyrt | Solid pharmaceutical composition containing polymorph i of clopidogrel hydrogensulfate and process for the preparation thereof |
| CN101951896B (zh) * | 2008-02-22 | 2012-11-28 | 韩兀生物制药株式会社 | 复合制剂 |
| CN101695496A (zh) * | 2009-10-15 | 2010-04-21 | 苏春华 | 一种含有三氟柳和氯吡格雷的药物组合物 |
| JP2013032289A (ja) * | 2009-10-28 | 2013-02-14 | Daiichi Sankyo Co Ltd | ワックス安定製剤 |
| RU2484820C2 (ru) * | 2011-02-24 | 2013-06-20 | Общество с ограниченной ответственностью "Озон" | Комбинированное лекарственное средство, являющееся ингибитором агрегации тромбоцитов |
| KR101675501B1 (ko) * | 2011-11-02 | 2016-11-14 | 한국유나이티드제약 주식회사 | 클로피도그렐 및 아스피린의 복합제제 |
| CN102406938A (zh) * | 2011-11-29 | 2012-04-11 | 北京阜康仁生物制药科技有限公司 | 一种抗血栓的药物组合物 |
| JP6004524B2 (ja) * | 2012-07-11 | 2016-10-12 | 大原薬品工業株式会社 | クロピドグレル硫酸塩含有錠剤の製造方法 |
| JP5905165B2 (ja) * | 2013-08-02 | 2016-04-20 | サノフイ | アセチルサリチル酸およびクロピドグレルを含む医薬錠剤 |
| CN104434932B (zh) * | 2014-12-18 | 2017-05-24 | 成都苑东生物制药股份有限公司 | 一种硫酸氢氯吡格雷阿司匹林片药物组合物及其制备方法 |
| WO2017037741A1 (fr) * | 2015-09-02 | 2017-03-09 | Sun Pharmaceutical Industries Ltd | Forme posologique solide et compacte à base d'aspirine et de clopidogrel |
| CN115737578A (zh) * | 2022-11-23 | 2023-03-07 | 石家庄四药有限公司 | 一种硫酸氢氯吡格雷阿司匹林复方片及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2623810B2 (fr) | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| US5576328A (en) * | 1994-01-31 | 1996-11-19 | Elf Sanofi | Method for the secondary prevention of ischemic events |
| FR2744918B1 (fr) | 1996-02-19 | 1998-05-07 | Sanofi Sa | Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique |
| FR2779726B1 (fr) | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
-
1999
- 1999-04-30 FR FR9905497A patent/FR2792836B3/fr not_active Expired - Fee Related
-
2000
- 2000-04-25 NZ NZ514248A patent/NZ514248A/xx unknown
- 2000-04-25 CA CA002371231A patent/CA2371231A1/fr not_active Abandoned
- 2000-04-25 EA EA200100959A patent/EA200100959A1/ru unknown
- 2000-04-25 CZ CZ20013887A patent/CZ20013887A3/cs unknown
- 2000-04-25 KR KR1020017013830A patent/KR20020005735A/ko not_active Withdrawn
- 2000-04-25 SK SK1554-2001A patent/SK15542001A3/sk unknown
- 2000-04-25 PL PL00351923A patent/PL351923A1/xx not_active Application Discontinuation
- 2000-04-25 EE EEP200100559A patent/EE200100559A/xx unknown
- 2000-04-25 MX MXPA01011071A patent/MXPA01011071A/es unknown
- 2000-04-25 CN CN00807001A patent/CN1359294A/zh active Pending
- 2000-04-25 HK HK02103639.9A patent/HK1041823A1/zh unknown
- 2000-04-25 HU HU0202329A patent/HUP0202329A2/hu unknown
- 2000-04-25 AU AU43036/00A patent/AU4303600A/en not_active Abandoned
- 2000-04-25 EP EP00922737A patent/EP1178809A1/fr not_active Withdrawn
- 2000-04-25 BR BR0010194-0A patent/BR0010194A/pt not_active Application Discontinuation
- 2000-04-25 JP JP2000615014A patent/JP2002543137A/ja not_active Withdrawn
- 2000-04-25 WO PCT/FR2000/001086 patent/WO2000066130A1/fr not_active Ceased
- 2000-04-25 TR TR2001/03039T patent/TR200103039T2/xx unknown
- 2000-04-25 IL IL14564800A patent/IL145648A0/xx unknown
- 2000-04-28 UY UY26131A patent/UY26131A1/es not_active Application Discontinuation
- 2000-04-28 AR ARP000102020A patent/AR023789A1/es unknown
-
2001
- 2001-09-25 IS IS6084A patent/IS6084A/is unknown
- 2001-10-29 NO NO20015295A patent/NO20015295L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL351923A1 (en) | 2003-06-30 |
| EA200100959A1 (ru) | 2002-06-27 |
| TR200103039T2 (tr) | 2002-01-21 |
| JP2002543137A (ja) | 2002-12-17 |
| IS6084A (is) | 2001-09-25 |
| NO20015295D0 (no) | 2001-10-29 |
| HUP0202329A2 (en) | 2002-10-28 |
| NO20015295L (no) | 2001-12-21 |
| IL145648A0 (en) | 2002-06-30 |
| FR2792836B3 (fr) | 2001-07-27 |
| BR0010194A (pt) | 2002-02-13 |
| CA2371231A1 (fr) | 2000-11-09 |
| UY26131A1 (es) | 2000-12-29 |
| HK1041823A1 (zh) | 2002-07-26 |
| AU4303600A (en) | 2000-11-17 |
| NZ514248A (en) | 2003-06-30 |
| KR20020005735A (ko) | 2002-01-17 |
| MXPA01011071A (es) | 2002-07-22 |
| FR2792836A1 (fr) | 2000-11-03 |
| AR023789A1 (es) | 2002-09-04 |
| EP1178809A1 (fr) | 2002-02-13 |
| WO2000066130A1 (fr) | 2000-11-09 |
| CZ20013887A3 (cs) | 2002-02-13 |
| SK15542001A3 (sk) | 2002-02-05 |
| CN1359294A (zh) | 2002-07-17 |
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