[go: up one dir, main page]

KR20020005735A - 아세틸살리실산 및 클로피도그렐 황산수소염을 포함하는단위 형태의 제약 조성물 - Google Patents

아세틸살리실산 및 클로피도그렐 황산수소염을 포함하는단위 형태의 제약 조성물 Download PDF

Info

Publication number
KR20020005735A
KR20020005735A KR1020017013830A KR20017013830A KR20020005735A KR 20020005735 A KR20020005735 A KR 20020005735A KR 1020017013830 A KR1020017013830 A KR 1020017013830A KR 20017013830 A KR20017013830 A KR 20017013830A KR 20020005735 A KR20020005735 A KR 20020005735A
Authority
KR
South Korea
Prior art keywords
acetylsalicylic acid
hydrogen sulfate
pharmaceutical composition
clopidogrel hydrogen
clopidogrel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020017013830A
Other languages
English (en)
Korean (ko)
Inventor
베르나르 아브라모비씨
쟝 레리띠에
Original Assignee
고든 라이트
사노피-신델라보
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 고든 라이트, 사노피-신델라보 filed Critical 고든 라이트
Publication of KR20020005735A publication Critical patent/KR20020005735A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020017013830A 1999-04-30 2000-04-25 아세틸살리실산 및 클로피도그렐 황산수소염을 포함하는단위 형태의 제약 조성물 Withdrawn KR20020005735A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9905497A FR2792836B3 (fr) 1999-04-30 1999-04-30 Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
FR99/05,497 1999-04-30
PCT/FR2000/001086 WO2000066130A1 (fr) 1999-04-30 2000-04-25 Composition pharmaceutique sous forme unitaire contenant de l'acide acetylsalicylique et de l'hydrogenosulfate de clopidogrel

Publications (1)

Publication Number Publication Date
KR20020005735A true KR20020005735A (ko) 2002-01-17

Family

ID=9545071

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017013830A Withdrawn KR20020005735A (ko) 1999-04-30 2000-04-25 아세틸살리실산 및 클로피도그렐 황산수소염을 포함하는단위 형태의 제약 조성물

Country Status (24)

Country Link
EP (1) EP1178809A1 (fr)
JP (1) JP2002543137A (fr)
KR (1) KR20020005735A (fr)
CN (1) CN1359294A (fr)
AR (1) AR023789A1 (fr)
AU (1) AU4303600A (fr)
BR (1) BR0010194A (fr)
CA (1) CA2371231A1 (fr)
CZ (1) CZ20013887A3 (fr)
EA (1) EA200100959A1 (fr)
EE (1) EE200100559A (fr)
FR (1) FR2792836B3 (fr)
HK (1) HK1041823A1 (fr)
HU (1) HUP0202329A2 (fr)
IL (1) IL145648A0 (fr)
IS (1) IS6084A (fr)
MX (1) MXPA01011071A (fr)
NO (1) NO20015295L (fr)
NZ (1) NZ514248A (fr)
PL (1) PL351923A1 (fr)
SK (1) SK15542001A3 (fr)
TR (1) TR200103039T2 (fr)
UY (1) UY26131A1 (fr)
WO (1) WO2000066130A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100341506C (zh) 2000-12-25 2007-10-10 三共株式会社 含有阿斯匹林的药用组合物
RU2180848C1 (ru) * 2001-01-30 2002-03-27 Плотников Марк Борисович Средство с антиагрегантной и гемореологической активностью
US6767913B2 (en) 2001-12-18 2004-07-27 Teva Pharmaceutical Industries Ltd. Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
US6800759B2 (en) 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
JP4917255B2 (ja) * 2003-10-16 2012-04-18 第一三共ヘルスケア株式会社 サリチル酸類含有経口組成物
WO2005070464A2 (fr) * 2004-01-21 2005-08-04 Biofarma Ilac Sanayi Ve Ticaret A.S. Formulation de comprimes de bisulfate de clopidogrel
US20070003615A1 (en) * 2005-06-13 2007-01-04 Elan Pharma International Limited Nanoparticulate clopidogrel and aspirin combination formulations
KR20070009851A (ko) * 2005-07-14 2007-01-19 씨제이 주식회사 클로피도그렐 황산수소염 함유 약학 조성물
EP1926736A4 (fr) * 2005-09-21 2010-08-25 Chong Kun Dang Pharm Corp Nouveau complexe de resinate de s-clopidogrel et procede pour le produire
KR20070044323A (ko) * 2005-10-24 2007-04-27 에스케이케미칼주식회사 보관안정성이 개선된 클로피도그렐 황산수소염 함유 경구용제제
US20100145053A1 (en) * 2006-04-05 2010-06-10 Cadila Healthcare Limited Modified release clopidogrel formulation
EP1900358A1 (fr) * 2006-09-16 2008-03-19 Cimex Pharma AG Formulations pharmaceutiques contenant du clopidogrel
HUP0600839A3 (en) * 2006-11-14 2008-09-29 Egis Gyogyszergyar Nyrt Solid pharmaceutical composition containing polymorph i of clopidogrel hydrogensulfate and process for the preparation thereof
EP2255797A4 (fr) * 2008-02-22 2011-09-07 Hanall Biopharma Co Ltd Préparation composite
CN101695496A (zh) * 2009-10-15 2010-04-21 苏春华 一种含有三氟柳和氯吡格雷的药物组合物
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
RU2484820C2 (ru) * 2011-02-24 2013-06-20 Общество с ограниченной ответственностью "Озон" Комбинированное лекарственное средство, являющееся ингибитором агрегации тромбоцитов
KR101675501B1 (ko) 2011-11-02 2016-11-14 한국유나이티드제약 주식회사 클로피도그렐 및 아스피린의 복합제제
CN102406938A (zh) * 2011-11-29 2012-04-11 北京阜康仁生物制药科技有限公司 一种抗血栓的药物组合物
JP6004524B2 (ja) * 2012-07-11 2016-10-12 大原薬品工業株式会社 クロピドグレル硫酸塩含有錠剤の製造方法
WO2015015062A1 (fr) * 2013-08-02 2015-02-05 Sanofi Comprime pharmaceutique comprenant de l'acide acetylsalicylique et du clopidogrel
CN104434932B (zh) * 2014-12-18 2017-05-24 成都苑东生物制药股份有限公司 一种硫酸氢氯吡格雷阿司匹林片药物组合物及其制备方法
WO2017037741A1 (fr) * 2015-09-02 2017-03-09 Sun Pharmaceutical Industries Ltd Forme posologique solide et compacte à base d'aspirine et de clopidogrel
CN115737578A (zh) * 2022-11-23 2023-03-07 石家庄四药有限公司 一种硫酸氢氯吡格雷阿司匹林复方片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
US5576328A (en) * 1994-01-31 1996-11-19 Elf Sanofi Method for the secondary prevention of ischemic events
FR2744918B1 (fr) 1996-02-19 1998-05-07 Sanofi Sa Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
FR2779726B1 (fr) 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel

Also Published As

Publication number Publication date
AR023789A1 (es) 2002-09-04
NZ514248A (en) 2003-06-30
FR2792836B3 (fr) 2001-07-27
CZ20013887A3 (cs) 2002-02-13
CA2371231A1 (fr) 2000-11-09
EP1178809A1 (fr) 2002-02-13
IL145648A0 (en) 2002-06-30
EE200100559A (et) 2003-02-17
NO20015295L (no) 2001-12-21
PL351923A1 (en) 2003-06-30
EA200100959A1 (ru) 2002-06-27
AU4303600A (en) 2000-11-17
BR0010194A (pt) 2002-02-13
MXPA01011071A (es) 2002-07-22
HUP0202329A2 (en) 2002-10-28
FR2792836A1 (fr) 2000-11-03
CN1359294A (zh) 2002-07-17
HK1041823A1 (zh) 2002-07-26
JP2002543137A (ja) 2002-12-17
SK15542001A3 (sk) 2002-02-05
UY26131A1 (es) 2000-12-29
IS6084A (is) 2001-09-25
WO2000066130A1 (fr) 2000-11-09
NO20015295D0 (no) 2001-10-29
TR200103039T2 (tr) 2002-01-21

Similar Documents

Publication Publication Date Title
KR20020005735A (ko) 아세틸살리실산 및 클로피도그렐 황산수소염을 포함하는단위 형태의 제약 조성물
FI79650C (fi) Foerfarande foer framstaellning av mopidamols instantformer.
JP3589977B2 (ja) 活性成分としてクロドロン酸塩および賦形剤としてケイ化微晶質セルロースを含む医薬製剤
KR880001090B1 (ko) 디피리다몰의 경구용 제형의 제조방법
US7976869B2 (en) Fenofibrate tablets
EP1397127B1 (fr) Preparations pharmaceutiques solides comprenant du modafinil
PL200957B1 (pl) Kompozycja farmaceutyczna celecoxib'u i zastosowanie kompozycji farmaceutycznej
HK87893A (en) Orally sustained-release acetaminophen formulation and process to obtain it
PL179080B1 (pl) Tabletka przeciwmigrenowa i sposób wytwarzania tabletki przeciwmigrenowej PL PL PL PL
NZ202140A (en) Delayed release nitrofurantoin tablets
KR20200082006A (ko) 토파시티닙 또는 그의 약제학적으로 허용되는 염을 함유한 서방성 제제 및 그의 제조방법
AU2006228947A1 (en) Combined-step process for pharmaceutical compositions
EP1556026B1 (fr) Nouvelles formulations pharmaceutiques du modafinil
EP1625849A1 (fr) Composition pharmaceutique contenant ethinylestradiol et drospirenone
EP0599767B1 (fr) Procédé pour préparer des comprimés hydro-dispersibles contenant du diclofenac
US20030004130A1 (en) Homogeneous pharmaceutical compositions containing zidovudine and lamivudine
JP3573287B2 (ja) 高吸収性固形製剤
US20080194560A1 (en) Disintegration promoters in solid dose wet granulation formulations
JP7424992B2 (ja) コーティング方法
KR20240145412A (ko) 아비라테론 아세테이트 및 프레드니솔론을 포함하는 약제학적 제제 및 이의 제조방법
KR20150042561A (ko) 위장질환 치료용 약학적 조성물
HK1061652B (en) Solid pharmaceutical formulations comprising modafinil
HK1078265B (en) Novel pharmaceutical formulations of modafinil
MXPA00007471A (es) Composiciones de celecoxib
HUE029193T2 (en) Delayed release drug formulations of thiocolchicoside

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20011029

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid