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EE04550B1 - Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon - Google Patents

Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon

Info

Publication number
EE04550B1
EE04550B1 EEP200000062A EEP200000062A EE04550B1 EE 04550 B1 EE04550 B1 EE 04550B1 EE P200000062 A EEP200000062 A EE P200000062A EE P200000062 A EEP200000062 A EE P200000062A EE 04550 B1 EE04550 B1 EE 04550B1
Authority
EE
Estonia
Prior art keywords
crystalline
medicament
manufacture
preparation
pharmaceutical composition
Prior art date
Application number
EEP200000062A
Other languages
English (en)
Inventor
William Snape Evan
Original Assignee
Zeneca Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Limited filed Critical Zeneca Limited
Publication of EE200000062A publication Critical patent/EE200000062A/et
Publication of EE04550B1 publication Critical patent/EE04550B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Liquid Crystal Substances (AREA)
EEP200000062A 1997-08-01 1998-07-28 Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon EE04550B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716161.6A GB9716161D0 (en) 1997-08-01 1997-08-01 Process
PCT/GB1998/002260 WO1999006381A1 (en) 1997-08-01 1998-07-28 A crystalline dibenzothiazepine derivative and its use as an antipsychotic agent

Publications (2)

Publication Number Publication Date
EE200000062A EE200000062A (et) 2000-10-16
EE04550B1 true EE04550B1 (et) 2005-10-17

Family

ID=10816746

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000062A EE04550B1 (et) 1997-08-01 1998-07-28 Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon

Country Status (31)

Country Link
US (2) US6372734B1 (et)
EP (2) EP1000043B1 (et)
JP (2) JP2001512109A (et)
KR (1) KR20010022241A (et)
CN (1) CN1125058C (et)
AT (2) ATE444959T1 (et)
AU (1) AU739255B2 (et)
BG (1) BG64796B1 (et)
BR (1) BR9811061A (et)
CA (1) CA2295792C (et)
CY (2) CY2200161T2 (et)
CZ (1) CZ299225B6 (et)
DE (4) DE69841216D1 (et)
EE (1) EE04550B1 (et)
ES (2) ES2296575T3 (et)
GB (2) GB9716161D0 (et)
HU (1) HU228620B1 (et)
ID (1) ID24219A (et)
IL (1) IL133618A (et)
MY (1) MY120999A (et)
NO (1) NO20000484L (et)
NZ (1) NZ501914A (et)
PL (1) PL338384A1 (et)
PT (2) PT1000043E (et)
RU (1) RU2224754C2 (et)
SI (2) SI1000043T1 (et)
SK (1) SK287145B6 (et)
TR (1) TR200000848T2 (et)
TW (1) TW533207B (et)
WO (1) WO1999006381A1 (et)
ZA (1) ZA986904B (et)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL164155A0 (en) * 2002-03-20 2005-12-18 Teva Pharma Crystalline forms of quetiapine hemifumarate
EP1495008A1 (en) 2003-02-22 2005-01-12 Teva Pharmaceutical Industries Limited Synthesis of quetiapine and pharmaceutically acceptable salts thereof
TR200503401T1 (tr) * 2003-03-03 2008-03-21 Hetero Drugs Limited Kuetiapin (Quetiapine) Fumarat'ın yeni polimorfları
US7053115B2 (en) 2003-04-07 2006-05-30 Hetero Drugs Limited Crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006035293A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Polymorphic forms of quetiapine hemifumarate
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
JP2008502707A (ja) * 2005-04-14 2008-01-31 テバ ファーマシューティカル インダストリーズ リミティド クエチアピンフマレートの調製方法
US20070072840A1 (en) * 2005-05-30 2007-03-29 Pandya Bhargav Polymorphic forms of quetiapine
EP1928849A1 (en) * 2005-09-30 2008-06-11 Fermion Oy New crystallization process of quetiapine hemifumarate
US8044039B2 (en) 2005-10-28 2011-10-25 Fermion Oy Quetiapine hemifumarate purification by crystallization
JP2009516705A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 塩の形態
EP1951693A4 (en) * 2005-11-18 2012-05-30 Astrazeneca Ab SOLID FORMULATIONS
CN101360502B (zh) * 2005-11-18 2012-03-14 阿斯利康公司 结晶形式
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
WO2007062339A2 (en) * 2005-11-18 2007-05-31 Astrazeneca Ab Liquid formulations
CZ300451B6 (cs) * 2006-07-03 2009-05-20 Farmak, A. S. Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) * 2006-10-20 2008-06-05 Concert Pharmaceuticals Inc. Dibenzothiazepine derivatives
PT1958617E (pt) 2007-02-14 2010-10-28 Lesvi Laboratorios Sl Composições farmacêuticas contendo fumarato de quetiapina
US20080241949A1 (en) * 2007-03-29 2008-10-02 Vinod Kumar Kansal Process for preparing quetiapine fumarate
WO2009004480A2 (en) * 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
US20090082334A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched quetiapine
CA2706903C (en) * 2007-12-05 2015-11-17 Henricus Jacobus Maria Gijsen Dibenzoazepine and dibenzooxazepine trpa1 agonists
PT2262486E (pt) 2008-08-01 2013-03-27 Tovarna Zdravil D D Novo Mesto Krka Composição de quetiapina
US20100069356A1 (en) * 2008-09-17 2010-03-18 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
WO2010100623A1 (en) 2009-03-04 2010-09-10 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
DK2742152T3 (en) 2011-08-12 2017-07-31 Qiagen Gmbh PROCEDURE FOR ISOLATING NUCLEIC ACIDS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787249A (fr) 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound

Also Published As

Publication number Publication date
PL338384A1 (en) 2000-10-23
EP1589008B1 (en) 2011-01-19
EP1000043A1 (en) 2000-05-17
HU228620B1 (en) 2013-04-29
TW533207B (en) 2003-05-21
KR20010022241A (ko) 2001-03-15
SI1000043T1 (sl) 2010-01-29
EP1589008A1 (en) 2005-10-26
PT1000043E (pt) 2009-11-30
ATE444959T1 (de) 2009-10-15
DE69842104D1 (de) 2011-03-03
ES2296568T3 (es) 2011-05-06
HK1029992A1 (en) 2001-04-20
CY2200161T2 (el) 2010-07-28
CN1265101A (zh) 2000-08-30
IL133618A (en) 2004-02-08
IL133618A0 (en) 2001-04-30
NO20000484D0 (no) 2000-01-31
NZ501914A (en) 2001-09-28
HK1081962A1 (en) 2006-05-26
ID24219A (id) 2000-07-13
CY2200162T2 (el) 2010-07-28
SK287145B6 (sk) 2010-01-07
JP2001512109A (ja) 2001-08-21
BR9811061A (pt) 2000-09-19
EE200000062A (et) 2000-10-16
SI1589008T1 (sl) 2011-04-29
BG104176A (en) 2000-08-31
AU739255B2 (en) 2001-10-04
HUP0002663A2 (hu) 2001-09-28
CN1125058C (zh) 2003-10-22
AU8549898A (en) 1999-02-22
RU2224754C2 (ru) 2004-02-27
BG64796B1 (bg) 2006-04-28
CA2295792A1 (en) 1999-02-11
GB9716161D0 (en) 1997-10-08
DE05011169T1 (de) 2008-11-06
JP2009102345A (ja) 2009-05-14
DE69841216D1 (de) 2009-11-19
ES2296575T1 (es) 2008-05-01
GB9814882D0 (en) 1998-09-09
SK1302000A3 (en) 2000-06-12
EP1000043B1 (en) 2009-10-07
CZ2000341A3 (cs) 2000-05-17
CA2295792C (en) 2007-04-17
WO1999006381A1 (en) 1999-02-11
PT1589008E (pt) 2011-03-23
DE98936529T1 (de) 2008-11-20
ES2296568T1 (es) 2008-05-01
ES2296575T3 (es) 2010-02-05
CZ299225B6 (cs) 2008-05-21
MY120999A (en) 2005-12-30
HUP0002663A3 (en) 2001-10-29
NO20000484L (no) 2000-03-16
US6372734B1 (en) 2002-04-16
ZA986904B (en) 1999-02-01
US20020147186A1 (en) 2002-10-10
ATE496037T1 (de) 2011-02-15
TR200000848T2 (tr) 2000-08-21

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20160728