DZ3009A1 - Dérivés de quinoléine-2-one à substituant hétéroaryle nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. - Google Patents
Dérivés de quinoléine-2-one à substituant hétéroaryle nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.Info
- Publication number
- DZ3009A1 DZ3009A1 DZ000021A DZ000021A DZ3009A1 DZ 3009 A1 DZ3009 A1 DZ 3009A1 DZ 000021 A DZ000021 A DZ 000021A DZ 000021 A DZ000021 A DZ 000021A DZ 3009 A1 DZ3009 A1 DZ 3009A1
- Authority
- DZ
- Algeria
- Prior art keywords
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- heteroaryl substituted
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11970299P | 1999-02-11 | 1999-02-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DZ3009A1 true DZ3009A1 (fr) | 2004-03-27 |
Family
ID=22385869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DZ000021A DZ3009A1 (fr) | 1999-02-11 | 2000-02-09 | Dérivés de quinoléine-2-one à substituant hétéroaryle nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
Country Status (39)
| Country | Link |
|---|---|
| US (3) | US6258824B1 (xx) |
| EP (1) | EP1150973B1 (xx) |
| JP (3) | JP4090200B2 (xx) |
| KR (1) | KR20010102073A (xx) |
| CN (1) | CN1340051A (xx) |
| AP (1) | AP2001002241A0 (xx) |
| AR (1) | AR028985A1 (xx) |
| AT (1) | ATE297916T1 (xx) |
| AU (1) | AU2124800A (xx) |
| BG (1) | BG105860A (xx) |
| BR (1) | BR0008202A (xx) |
| CA (1) | CA2362394C (xx) |
| CO (1) | CO5140097A1 (xx) |
| CZ (1) | CZ20012910A3 (xx) |
| DE (1) | DE60020812T2 (xx) |
| DZ (1) | DZ3009A1 (xx) |
| EA (1) | EA200100766A1 (xx) |
| EE (1) | EE200100425A (xx) |
| ES (1) | ES2243228T3 (xx) |
| GT (1) | GT200000014A (xx) |
| HK (1) | HK1042096A1 (xx) |
| HN (1) | HN2000000019A (xx) |
| HR (1) | HRP20010574A2 (xx) |
| HU (1) | HUP0105231A3 (xx) |
| ID (1) | ID29584A (xx) |
| IL (1) | IL144307A0 (xx) |
| IS (1) | IS5997A (xx) |
| MA (1) | MA26718A1 (xx) |
| NO (1) | NO20013909L (xx) |
| OA (1) | OA11833A (xx) |
| PA (1) | PA8490601A1 (xx) |
| PE (1) | PE20001464A1 (xx) |
| PL (1) | PL349839A1 (xx) |
| SK (1) | SK11002001A3 (xx) |
| SV (1) | SV2001000020A (xx) |
| TN (1) | TNSN00028A1 (xx) |
| TR (2) | TR200201297T2 (xx) |
| WO (1) | WO2000047574A1 (xx) |
| ZA (1) | ZA200106520B (xx) |
Families Citing this family (92)
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| WO2001034591A2 (en) * | 1999-11-05 | 2001-05-17 | Cytovia, Inc. | Substituted 4h-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| EP1106612B1 (en) * | 1999-11-30 | 2004-02-11 | Pfizer Products Inc. | Quinoline derivatives useful for inhibiting farnesyl protein transferase |
| HN2000000266A (es) * | 2000-01-21 | 2001-05-21 | Pfizer Prod Inc | Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto. |
| CA2396593A1 (en) * | 2000-01-28 | 2001-08-02 | Merck & Co., Inc. | Treatment or prevention of prostate cancer with a cox-2 selective inhibiting drug |
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| EP1170011A1 (en) * | 2000-07-06 | 2002-01-09 | Boehringer Ingelheim International GmbH | Novel use of inhibitors of the epidermal growth factor receptor |
| EP1322636A1 (en) | 2000-09-25 | 2003-07-02 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6- (substituted phenyl)methyl]-quinoline and quinazoline derivatives |
| DE60118225T2 (de) | 2000-09-25 | 2007-05-03 | Janssen Pharmaceutica N.V. | Chinolin- und chinazolinderivate und deren verwendung als farnesyl transferase inhibitoren |
| US7196094B2 (en) | 2000-09-25 | 2007-03-27 | Janssen Pharmaceutica, N.V. | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives |
| US7067531B2 (en) | 2000-09-25 | 2006-06-27 | Angibaud Patrick Rene | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives |
| SK5212003A3 (en) * | 2000-10-02 | 2004-03-02 | Janssen Pharmaceutica Nv | Metabotropic glutamate receptor antagonists |
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| DE60117847T2 (de) | 2000-12-27 | 2006-11-16 | Janssen Pharmaceutica N.V. | Farnesyltransferase hemmende, in der 4-stellung substituierte chinolin- und chinazolinderivate |
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| EP1392283A4 (en) * | 2001-05-16 | 2004-10-20 | Cytovia Inc | SUBSTITUTED CUMARINE AND CHINOLINE AS CASPASE ACTIVATORS |
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| US20030139332A1 (en) * | 2001-07-09 | 2003-07-24 | The Regents Of The University Of California | Use of matrix metalloproteinase inhibitors to mitigate nerve damage |
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| CN101517068B (zh) * | 2005-09-07 | 2017-02-08 | 安进弗里蒙特公司 | 活化素受体样激酶‑1的人单克隆抗体 |
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| MX2018006781A (es) | 2015-12-03 | 2018-11-09 | Agios Pharmaceuticals Inc | Inhibidores de mat2a para el tratamiento del cancer que no expresen mtap. |
| CN108003150A (zh) * | 2016-10-31 | 2018-05-08 | 河南工业大学 | 4-杂芳基喹啉酮衍生物的制备方法及其应用 |
| EP3826684A4 (en) | 2018-07-26 | 2022-04-06 | Sumitomo Dainippon Pharma Oncology, Inc. | METHODS OF TREATMENT OF DISEASES ASSOCIATED WITH ABNORMAL ACVR1 EXPRESSION AND ACVR1 INHIBITORS FOR USE IN THE SAME |
| JP7662528B2 (ja) | 2019-02-12 | 2025-04-15 | スミトモ ファーマ アメリカ, インコーポレイテッド | 複素環式タンパク質キナーゼ阻害剤を含む製剤 |
| JP7718659B2 (ja) | 2019-08-16 | 2025-08-05 | チルドレンズ ホスピタル メディカル センター | Cdc42特異的阻害剤で対象を治療する方法 |
| WO2021155006A1 (en) | 2020-01-31 | 2021-08-05 | Les Laboratoires Servier Sas | Inhibitors of cyclin-dependent kinases and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2732531A1 (de) * | 1977-07-19 | 1979-02-01 | Hoechst Ag | Imidazolcarbonsaeuren und deren derivate |
| US4835154A (en) * | 1987-06-01 | 1989-05-30 | Smithkline Beckman Corporation | 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors |
| US5053543A (en) * | 1990-11-28 | 1991-10-01 | Glaxo Inc. | Synthesis of 2-aminobenzophenones |
| US5136085A (en) * | 1990-11-28 | 1992-08-04 | Glaxo Inc. | Synthesis of 2-aminobenzophenones |
| TW349948B (en) | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| IL123568A (en) * | 1995-12-08 | 2001-08-08 | Janssen Pharmaceutica Nv | History (Imidazole - 5Il) Methyl-2-quinolinone inhibitors of Prenzyl transferase, their preparation, pharmaceutical preparations containing them and their preparation and drugs containing them |
| CN1231215C (zh) * | 1997-06-02 | 2005-12-14 | 詹森药业有限公司 | (咪唑-5-基)甲基-2-喹啉酮衍生物用作平滑肌细胞增殖抑制剂 |
| GEP20033001B (en) | 1998-08-27 | 2003-06-25 | Pfizer Prod Inc | Alkynyl-Substituted Quinolin-2-One Derivatives Useful As Anticancer Agents |
| JP4090200B2 (ja) * | 1999-02-11 | 2008-05-28 | ファイザー・プロダクツ・インク | 抗癌薬として有用なヘテロアリール置換キノリン−2−オン誘導体 |
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