DZ2465A1 - Pyrazolopyrimidinones nouvelles procédé pour leur préparation et compositions les contenant. - Google Patents

Pyrazolopyrimidinones nouvelles procédé pour leur préparation et compositions les contenant.

Info

Publication number: DZ2465A1
Authority: DZ; Algeria
Prior art keywords: pyrazolopyrimidinones; preparation; new; compositions containing; compositions
Prior art date: 1997-04-25

Application number

DZ980076A

Other languages

English (en)

French (fr)

Inventor

Mark Edward Bunnage

John Paul Mathias

Stephen Derek Albert Street

Anthony Wood

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-25

Filing date

1998-04-22

Publication date

2003-01-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27268823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ2465(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-04-25 Priority claimed from GBGB9708406.5A external-priority patent/GB9708406D0/en

1997-07-22 Priority claimed from GB9715380A external-priority patent/GB9715380D0/en

1997-10-30 Priority claimed from GBGB9722954.6A external-priority patent/GB9722954D0/en

1998-04-22 Application filed by Pfizer filed Critical Pfizer

2003-01-18 Application granted granted Critical

2003-01-18 Publication of DZ2465A1 publication Critical patent/DZ2465A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Vascular Medicine (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

DZ980076A 1997-04-25 1998-04-22 Pyrazolopyrimidinones nouvelles procédé pour leur préparation et compositions les contenant. DZ2465A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9708406.5A GB9708406D0 (en)	1997-04-25	1997-04-25	Therapeutic agents
GB9715380A GB9715380D0 (en)	1997-07-22	1997-07-22	Therapeutic agents
GBGB9722954.6A GB9722954D0 (en)	1997-10-30	1997-10-30	Therapeutic agents

Publications (1)

Publication Number	Publication Date
DZ2465A1 true DZ2465A1 (fr)	2003-01-18

Family

ID=27268823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980076A DZ2465A1 (fr)	1997-04-25	1998-04-22	Pyrazolopyrimidinones nouvelles procédé pour leur préparation et compositions les contenant.

Country Status (31)

Country	Link
US (2)	US6723719B1 (xx)
EP (1)	EP0977756A1 (xx)
JP (2)	JP3563078B2 (xx)
KR (2)	KR100390612B1 (xx)
CN (2)	CN1281588C (xx)
AP (1)	AP1002A (xx)
AR (1)	AR015595A1 (xx)
AU (1)	AU730670B2 (xx)
BG (1)	BG103828A (xx)
BR (1)	BR9810233A (xx)
CA (1)	CA2288910C (xx)
CO (1)	CO4940472A1 (xx)
CZ (1)	CZ299633B6 (xx)
DZ (1)	DZ2465A1 (xx)
EA (2)	EA002057B1 (xx)
HR (1)	HRP980222B1 (xx)
ID (1)	ID22834A (xx)
IL (5)	IL132276A0 (xx)
IS (1)	IS5200A (xx)
MA (1)	MA24529A1 (xx)
NO (1)	NO314585B1 (xx)
NZ (1)	NZ338075A (xx)
OA (1)	OA11168A (xx)
PA (1)	PA8450401A1 (xx)
PE (1)	PE68699A1 (xx)
PL (1)	PL336586A1 (xx)
RS (1)	RS50118B (xx)
SK (1)	SK285991B6 (xx)
TN (1)	TNSN98053A1 (xx)
TR (1)	TR199902646T2 (xx)
WO (1)	WO1998049166A1 (xx)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9423910D0 (en) *	1994-11-26	1995-01-11	Pfizer Ltd	Therapeutic agents
IL120266A (en)	1996-02-28	2005-05-17	Pfizer	Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
GB9612514D0 (en) *	1996-06-14	1996-08-14	Pfizer Ltd	Novel process
US6331543B1 (en)	1996-11-01	2001-12-18	Nitromed, Inc.	Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
PL336586A1 (en)	1997-04-25	2000-07-03	Pfizer	Pyrazoylpyrimidinones inhibiting the cyclic guanosine 3',5'-monophosphate phosphodiesterase of type 5 (cgmp pde5) for treating sexual disorders
GB9722520D0 (en)	1997-10-24	1997-12-24	Pfizer Ltd	Compounds
HUP0102543A3 (en) *	1998-04-20	2002-01-28	Pfizer	Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
DE19827640A1 (de)	1998-06-20	1999-12-23	Bayer Ag	7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
GB9822238D0 (en) *	1998-10-12	1998-12-09	Pfizer Ltd	Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
GB9823102D0 (en)	1998-10-23	1998-12-16	Pfizer Ltd	Pharmaceutically active compounds
GB9823101D0 (en) *	1998-10-23	1998-12-16	Pfizer Ltd	Pharmaceutically active compounds
GB9823103D0 (en) *	1998-10-23	1998-12-16	Pfizer Ltd	Pharmaceutically active compounds
KR100353014B1 (ko) *	1998-11-11	2002-09-18	동아제약 주식회사	발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
RU2220145C2 (ru) *	1998-11-11	2003-12-27	Донг А Фарм. Ко., Лтд.	Производные пиразолопиримидинона для лечения импотенции и способ их получения
US6225315B1 (en)	1998-11-30	2001-05-01	Pfizer Inc	Method of treating nitrate-induced tolerance
WO2000066114A1 (en) *	1999-04-30	2000-11-09	Lilly Icos Llc	Treatment of female arousal disorder
IL135817A0 (en) *	1999-04-30	2001-05-20	Lilly Icos Llc	Phosphodiesterase enzyme inhibitors and their use in pharmaceutical articles
DE69904025T2 (de) *	1999-06-04	2003-07-31	The Jordanian Pharmaceutical Manufacturing And Medical Equipment Co. Ltd., Jo-Naor	Kondensierte Pyrimidinderivate und diese enthaltende pharmazeutische Zubereitungen
US6242444B1 (en)	1999-06-04	2001-06-05	The Jordanian Pharmaceutical Manufacturing And Medical Equipment Co., Ltd.	Compounds and pharmaceutical compositions containing the same
ES2166270B1 (es) *	1999-07-27	2003-04-01	Almirall Prodesfarma Sa	Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona.
DE19942474A1 (de)	1999-09-06	2001-03-15	Merck Patent Gmbh	Pyrazolo[4,3-d]pyrimidine
YU59100A (sh) *	1999-10-11	2003-10-31	Pfizer Inc.	Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera
NZ517324A (en)	1999-10-11	2003-09-26	Pfizer	5-(2-substituted-5-heterocyclylsulphonylpyrid-3-YL)- dihydropyrazolo[4,3-d]pyrimidin-7-ones as phosphodiesterase inhibitors
TWI265925B (en)	1999-10-11	2006-11-11	Pfizer	Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
GB9923968D0 (en) *	1999-10-11	1999-12-15	Pfizer Ltd	Therapeutic agents
US6350751B1 (en)	1999-10-11	2002-02-26	Pfizer Inc.	Therapeutic agents
TW200400821A (en) *	1999-11-02	2004-01-16	Pfizer	Pharmaceutical composition (II) useful for treating or preventing pulmonary hypertension in a patient
CA2395410A1 (en) *	1999-12-24	2001-07-05	Bayer Aktiengesellschaft	Triazolotriazinones and the use thereof
AU781028B2 (en) *	1999-12-24	2005-04-28	Bayer Aktiengesellschaft	Imidazo (1,3,5) triazinones and the use thereof
KR100358083B1 (ko) *	2000-02-17	2002-10-25	에스케이케미칼주식회사	피롤로피리미디논 유도체와 이의 제조방법, 그리고 이의용도
AU2000254308A1 (en) *	2000-05-17	2001-11-26	Sk Chemicals Co., Ltd.	Pyrazolopyrimidinone derivatives, process for their preparation and their use
KR100377782B1 (ko) *	2000-06-23	2003-03-29	동아제약 주식회사	발기부전 치료에 효과를 갖는 피라졸로피리미디논화합물의 제조방법
US6407259B1 (en)	2000-07-28	2002-06-18	Pfizer Inc.	Process for the preparation of pyrazoles
EP1176142A1 (en) *	2000-07-28	2002-01-30	Pfizer Inc.	Process for the preparation of pyrazoles
AU2001276607A1 (en) *	2000-08-11	2002-02-25	Pfizer Inc.	Treatment of the insulin resistance syndrome with selective CGMP PDE5 inhibitors
PE20020394A1 (es)	2000-08-18	2002-06-21	Agouron Pharma	Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2
AU2000267375A1 (en) *	2000-08-23	2002-03-04	Lg Life Sciences Ltd.	Polyethoxylated pyrazolo pyrimidinone derivatives, process for preparation thereof and pharmaceutical compositions comprising the same for the treatment of impotence
US6821978B2 (en)	2000-09-19	2004-11-23	Schering Corporation	Xanthine phosphodiesterase V inhibitors
GB0025782D0 (en) *	2000-10-20	2000-12-06	Pfizer Ltd	Use of inhibitors
US6548508B2 (en)	2000-10-20	2003-04-15	Pfizer, Inc.	Use of PDE V inhibitors for improved fecundity in mammals
SE0004780D0 (sv)	2000-12-22	2000-12-22	Jordanian Pharmaceutical Mfg &	Novel compunds
MXPA04004370A (es)	2001-11-09	2004-08-11	Schering Corp	Derivados policiclicos de guanina inhibidores de fosfodiesterasa v.
GB0129274D0 (en) *	2001-12-06	2002-01-23	Pfizer Ltd	Novel kit
EP1348707B1 (en) *	2002-03-28	2010-08-25	Ustav Experimentalni Botaniky AV CR, v.v.i. (Institute of Experimental Botany Academy of Sciences of the Czech Republic, PRO)	Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy
GB0219961D0 (en)	2002-08-28	2002-10-02	Pfizer Ltd	Oxytocin inhibitors
US7323462B2 (en)	2002-12-10	2008-01-29	Pfizer Inc.	Morpholine dopamine agonists
DK1572173T3 (da)	2002-12-13	2010-06-14	Warner Lambert Co	Alpha-2-delta-ligand til behandling af symptomer i den nedre urinvej
CA2523831C (en)	2003-04-29	2008-11-18	Pfizer Inc.	5,7-diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension
NZ544756A (en) *	2003-07-22	2009-09-25	Astex Therapeutics Ltd	3,4-Disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators
US7291640B2 (en)	2003-09-22	2007-11-06	Pfizer Inc.	Substituted triazole derivatives as oxytocin antagonists
US7572799B2 (en)	2003-11-24	2009-08-11	Pfizer Inc	Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
EP1779852A3 (en) *	2004-01-05	2007-05-09	Teva Pharmaceutical Industries Ltd.	Processes for the production of sildenafil base and citrate salt
ATE387203T1 (de)	2004-01-05	2008-03-15	Teva Pharma	Prozesse zur herstellung von sildenafil-base und zitratsalz
WO2005079808A1 (en)	2004-01-22	2005-09-01	Pfizer Limited	Triazole derivatives which inhibit vasopressin antagonistic activity
US7649002B2 (en)	2004-02-04	2010-01-19	Pfizer Inc	(3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists
DK1742950T3 (da)	2004-04-07	2009-03-16	Pfizer Ltd	Pyrazolo-[4,3-D]-pyrimidiner
US7897607B2 (en) *	2004-04-07	2011-03-01	Takeda Pharmaceutical Company Limited	Cyclic compounds
US8299083B2 (en)	2004-08-17	2012-10-30	The Johns Hopkins University	PDE5 inhibitor compositions and methods for treating cardiac indications
TWI367098B (en) *	2004-12-23	2012-07-01	Kowa Co	Treating agent for glaucoma
US8404718B2 (en)	2005-01-21	2013-03-26	Astex Therapeutics Limited	Combinations of pyrazole kinase inhibitors
AR054425A1 (es)	2005-01-21	2007-06-27	Astex Therapeutics Ltd	Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico.
WO2006100557A1 (en)	2005-03-21	2006-09-28	Pfizer Limited	Substituted triazole derivatives as oxytocin antagonists
WO2006111495A1 (en)	2005-04-19	2006-10-26	Nycomed Gmbh	Roflumilast for the treatment of pulmonary hypertension
US8506934B2 (en)	2005-04-29	2013-08-13	Robert I. Henkin	Methods for detection of biological substances
NZ564187A (en)	2005-05-12	2010-03-26	Pfizer	Anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide
JP2009514969A (ja)	2005-11-09	2009-04-09	コンビナトアールエックスインコーポレーティッド	医学的状態を治療するための方法、組成物、およびキット
EP1965863A2 (en) *	2005-12-20	2008-09-10	Pfizer Products Inc.	Pharmaceutical combination for the treatment of luts comprising a pde5 inhibitor and a muscarinic antagonist
GB0601951D0 (en)	2006-01-31	2006-03-15	Novartis Ag	Organic compounds
US8293489B2 (en)	2007-01-31	2012-10-23	Henkin Robert I	Methods for detection of biological substances
US8580801B2 (en)	2008-07-23	2013-11-12	Robert I. Henkin	Phosphodiesterase inhibitor treatment
CN101747282A (zh)	2008-12-10	2010-06-23	上海特化医药科技有限公司	一类含有嘧啶酮苯基的化合物、其药物组合物及其制备方法和用途
JP2012513464A (ja)	2008-12-23	2012-06-14	ザトラスティーズオブコロンビアユニヴァーシティインザシティオブニューヨーク	ホスホジエステラーゼ阻害剤及びその使用
GB0903493D0 (en)	2009-02-27	2009-04-08	Vantia Ltd	New compounds
TWI462739B (zh)	2010-11-02	2014-12-01	Univ Kaohsiung Medical	Ｓｉｌｄｅｎａｆｉｌ－同族物四級銨哌嗪鹽類之製備及醫療用途
CN105360132A (zh)	2010-11-03	2016-03-02	陶氏益农公司	杀虫组合物和与其相关的方法
CN102134242B (zh) *	2011-01-21	2013-08-28	浙江大德药业集团有限公司	一种用于治疗阳痿的快速长效的化合物
EP2753332B1 (en)	2011-09-09	2017-02-15	SK Chemicals Co., Ltd.	Mridenafil for reducing skin wrinkles
ES2899850T3 (es)	2011-10-26	2022-03-15	Corteva Agriscience Llc	Composiciones plaguicidas y procedimientos relacionados con las mismas
WO2013067309A1 (en)	2011-11-04	2013-05-10	Xion Pharmaceutical Corporation	Methods and compositions for oral administration of melanocortin receptor agonist compounds
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
WO2013109738A1 (en)	2012-01-17	2013-07-25	The Trustees Of Columbia University In The City Of New York	Novel phosphodiesterase inhibitors and uses thereof
US9708288B2 (en)	2012-04-27	2017-07-18	Dow Agrosciences Llc	Pesticidal compositions and processes related thereto
MX2014013069A (es)	2012-04-27	2015-07-06	Dow Agrosciences Llc	Composiciones plaguicidas y procesos relacionados.
US9282739B2 (en)	2012-04-27	2016-03-15	Dow Agrosciences Llc	Pesticidal compositions and processes related thereto
US20150297601A1 (en)	2012-10-05	2015-10-22	Robert I. Henkin	Phosphodiesterase inhibitor treatment
ES2882258T3 (es)	2012-12-21	2021-12-01	Mayo Found Medical Education & Res	Métodos y materiales para tratar estenosis de la válvula aórtica calcificada
CN103265479B (zh) *	2013-06-14	2017-12-08	南开大学	一种6‑氯甲基烟酸叔丁酯的合成方法
US10899756B2 (en)	2013-07-17	2021-01-26	The Trustees Of Columbia University In The City Of New York	Phosphodiesterase inhibitors and uses thereof
EP3057431A4 (en)	2013-10-17	2017-04-05	Dow AgroSciences LLC	Processes for the preparation of pesticidal compounds
JP2016536295A (ja)	2013-10-17	2016-11-24	ダウアグロサイエンシィズエルエルシー	有害生物防除性化合物の製造方法
CN105636440A (zh)	2013-10-17	2016-06-01	美国陶氏益农公司	制备杀虫化合物的方法
CA2926095A1 (en)	2013-10-17	2015-04-23	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
CN105636446B (zh)	2013-10-17	2018-07-13	美国陶氏益农公司	制备杀虫化合物的方法
MX2016004942A (es)	2013-10-17	2016-06-28	Dow Agrosciences Llc	Procesos para la preparacion de compuestos plaguicidas.
JP6487426B2 (ja)	2013-10-17	2019-03-20	ダウアグロサイエンシィズエルエルシー	有害生物防除化合物の調製法
EP3060051A4 (en)	2013-10-22	2017-04-05	Dow AgroSciences LLC	Synergistic pesticidal compositions and related methods
RU2016119571A (ru)	2013-10-22	2017-11-28	ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи	Синергетические пестицидные композиции и связанные с ними способы
WO2015061147A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
AR098096A1 (es)	2013-10-22	2016-05-04	Dow Agrosciences Llc	Composiciones plaguicidas sinérgicas y métodos relacionados
CA2926345A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
KR20160074633A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
KR20160074582A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
TW201519782A (zh)	2013-10-22	2015-06-01	Dow Agrosciences Llc	殺蟲組成物及相關方法（五）
CA2926101C (en)	2013-10-22	2022-05-31	Dow Agrosciences Llc	Pesticidal compositions and related methods
CA2927195A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
AU2014340430B2 (en)	2013-10-22	2017-05-25	Dow Agrosciences Llc	Pesticidal compositions and related methods
CN105658062A (zh)	2013-10-22	2016-06-08	美国陶氏益农公司	协同杀虫组合物和相关方法
KR20160074635A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
EP3060046A4 (en)	2013-10-22	2017-07-26	Dow AgroSciences LLC	Pesticidal compositions and related methods
CN105848481A (zh)	2013-10-22	2016-08-10	美国陶氏益农公司	协同杀虫组合物和相关方法
EP3060047A4 (en)	2013-10-22	2017-04-26	Dow AgroSciences, LLC	Pesticidal compositions and related methods
KR102286233B1 (ko)	2013-10-22	2021-08-06	코르테바 애그리사이언스 엘엘씨	살충 조성물 및 관련 방법
US10598672B2 (en)	2014-02-18	2020-03-24	Cyrano Therapeutics, Inc.	Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
BR112017000418A2 (pt)	2014-07-31	2017-11-07	Dow Agrosciences Llc	processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina
EP3186230A4 (en)	2014-07-31	2018-01-10	Dow AgroSciences, LLC	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CA2954345A1 (en)	2014-07-31	2016-02-04	Dow Agrosciences Llc	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
EP3183238A4 (en)	2014-08-19	2018-01-10	Dow AgroSciences LLC	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
BR112017004613A2 (pt)	2014-09-12	2017-12-05	Dow Agrosciences Llc	processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina
WO2016044667A1 (en) *	2014-09-17	2016-03-24	Intra-Cellular Therapies, Inc.	Compounds and methods
WO2016145614A1 (en)	2015-03-17	2016-09-22	Merck Sharp & Dohme Corp.	Triazolyl pyrimidinone compounds as pde2 inhibitors
WO2016183741A1 (en) *	2015-05-15	2016-11-24	Merck Sharp & Dohme Corp.	Pyrimidinone amide compounds as pde2 inhibitors
US20180072741A1 (en)	2016-09-09	2018-03-15	Incyte Corporation	Pyrazolopyrimidine compounds and uses thereof
MA46191A (fr)	2016-09-09	2021-04-21	Incyte Corp	Dérivés de pyrazolopyridine comme modulateurs de hpk1 et leurs utilisations pour le traitement du cancer
US20180072718A1 (en)	2016-09-09	2018-03-15	Incyte Corporation	Pyrazolopyridine compounds and uses thereof
US10100033B2 (en)	2016-12-29	2018-10-16	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
WO2018125817A1 (en)	2016-12-29	2018-07-05	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
US20180228786A1 (en)	2017-02-15	2018-08-16	Incyte Corporation	Pyrazolopyridine compounds and uses thereof
WO2019051199A1 (en)	2017-09-08	2019-03-14	Incyte Corporation	6-CYANO-INDAZOLE COMPOUNDS AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) MODULATORS
US10745388B2 (en)	2018-02-20	2020-08-18	Incyte Corporation	Indazole compounds and uses thereof
SMT202200294T1 (it)	2018-02-20	2022-11-18	Incyte Corp	Derivati di n-(fenil)-2-(fenil)pirimidina-4-carbossammide e composti correlati come inibitori di hpk1 per trattare il cancro
WO2019164847A1 (en)	2018-02-20	2019-08-29	Incyte Corporation	Indazole compounds and uses thereof
US11299473B2 (en)	2018-04-13	2022-04-12	Incyte Corporation	Benzimidazole and indole compounds and uses thereof
US10899755B2 (en)	2018-08-08	2021-01-26	Incyte Corporation	Benzothiazole compounds and uses thereof
EP3856348B1 (en)	2018-09-25	2024-01-03	Incyte Corporation	Pyrazolo[4,3-d]pyrimidine compounds as alk2 and/or fgfr modulators
JP7652691B2 (ja) *	2018-11-28	2025-03-27	トパデュールファルマアーゲー	新規の二重作用型可溶性グアニル酸シクラーゼ活性化剤およびホスホジエステラーゼ阻害剤とその使用法
US12465605B2 (en)	2019-04-10	2025-11-11	Mayo Foundation For Medical Education And Research	Methods and materials for gender-dependent treatment of cardiovascular dysfunction
KR20220059480A (ko)	2019-08-06	2022-05-10	인사이트 코포레이션	고체 형태의 hpk1 억제제
CN113493459B (zh) *	2020-04-07	2022-12-13	广州白云山医药集团股份有限公司白云山制药总厂	Pde5抑制剂化合物及其制备方法和应用
CN113754612B (zh) *	2021-10-26	2023-09-26	山东安舜制药有限公司	一种西地那非中间体的制备方法
CN115785101B (zh) *	2022-11-23	2023-10-13	西安市食品药品检验所	一种含有苯基哌嗪结构的那非类化合物及其制备方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3992441A (en)	1972-12-26	1976-11-16	Pfizer Inc.	Sulfamylbenzoic acids
DE3420985A1 (de)	1983-10-15	1985-04-25	Bayer Ag, 5090 Leverkusen	Substituierte 5-acylamino-1-phenylpyrazole
US4871843A (en)	1983-10-18	1989-10-03	Dropic-Societe Civile De Gestion De Droits De Propriete Industrielle	Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions
US4663326A (en)	1985-04-04	1987-05-05	Warner-Lambert Company	Pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)dione or -5-thione-7-one analogs
US4666908A (en) *	1985-04-05	1987-05-19	Warner-Lambert Company	5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use
US5075310A (en)	1988-07-01	1991-12-24	Smith Kline & French Laboratories, Ltd.	Pyrimidone derivatives as bronchodilators
GB8817651D0 (en)	1988-07-25	1988-09-01	Smith Kline French Lab	Chemical compounds
GB8827988D0 (en)	1988-11-30	1989-01-05	Smith Kline French Lab	Chemical compounds
GB8928346D0 (en)	1989-12-15	1990-02-21	Smith Kline French Lab	Chemical compounds
GB9013750D0 (en)	1990-06-20	1990-08-08	Pfizer Ltd	Therapeutic agents
US5250534A (en)	1990-06-20	1993-10-05	Pfizer Inc.	Pyrazolopyrimidinone antianginal agents
GB9114760D0 (en)	1991-07-09	1991-08-28	Pfizer Ltd	Therapeutic agents
GB9119704D0 (en)	1991-09-14	1991-10-30	Pfizer Ltd	Therapeutic agents
GB9121028D0 (en)	1991-10-03	1991-11-13	Pfizer Ltd	Therapeutic agents
GB9126260D0 (en)	1991-12-11	1992-02-12	Pfizer Ltd	Therapeutic agents
GB9202238D0 (en)	1992-02-03	1992-03-18	Wellcome Found	Compounds
US5294612A (en)	1992-03-30	1994-03-15	Sterling Winthrop Inc.	6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
GB9213623D0 (en)	1992-06-26	1992-08-12	Pfizer Ltd	Therapeutic agents
US5734053A (en)	1992-06-26	1998-03-31	Pfizer Inc	Purinone antianginal agents
JP2657760B2 (ja)	1992-07-15	1997-09-24	小野薬品工業株式会社	４−アミノキナゾリン誘導体およびそれを含有する医薬品
GB9218322D0 (en)	1992-08-28	1992-10-14	Pfizer Ltd	Therapeutic agents
GB9301192D0 (en) *	1993-06-09	1993-06-09	Trott Francis W	Flower shaped mechanised table
GB9315017D0 (en)	1993-07-20	1993-09-01	Glaxo Lab Sa	Chemical compounds
GB9423911D0 (en)	1994-11-26	1995-01-11	Pfizer Ltd	Therapeutic agents
GB9423910D0 (en)	1994-11-26	1995-01-11	Pfizer Ltd	Therapeutic agents
NZ303886A (en)	1995-03-10	1998-11-25	Sanofi Winthrop Inc	1-cyclopentyl (or tert butyl)-6-aryl (or heteroaryl)-pyrazolo[3,4-d]pyrimidin-4-one derivatives and medicaments
US5656629A (en)	1995-03-10	1997-08-12	Sanofi Winthrop, Inc.	6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof
GB9612514D0 (en)	1996-06-14	1996-08-14	Pfizer Ltd	Novel process
PL336586A1 (en)	1997-04-25	2000-07-03	Pfizer	Pyrazoylpyrimidinones inhibiting the cyclic guanosine 3',5'-monophosphate phosphodiesterase of type 5 (cgmp pde5) for treating sexual disorders
HUP0102543A3 (en)	1998-04-20	2002-01-28	Pfizer	Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
US6087368A (en)	1998-06-08	2000-07-11	Bristol-Myers Squibb Company	Quinazolinone inhibitors of cGMP phosphodiesterase

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Publication number	Publication date
CN1281588C (zh)	2006-10-25
EA002057B1 (ru)	2001-12-24
AP9801228A0 (en)	1998-06-30
US6723719B1 (en)	2004-04-20
PE68699A1 (es)	1999-07-10
PA8450401A1 (es)	2000-05-24
EP0977756A1 (en)	2000-02-09
CN1626516A (zh)	2005-06-15
CZ299633B6 (cs)	2008-09-24
HRP980222A2 (en)	1999-02-28
CA2288910A1 (en)	1998-11-05
AU730670B2 (en)	2001-03-08
IL157645A (en)	2007-03-08
AR015595A1 (es)	2001-05-16
HRP980222B1 (en)	2003-12-31
CO4940472A1 (es)	2000-07-24
OA11168A (en)	2003-04-28
CZ376799A3 (cs)	2000-04-12
SK144699A3 (en)	2001-03-12
IL157647A (en)	2007-05-15
NZ338075A (en)	2000-10-27
IL132276A0 (en)	2001-03-19
ID22834A (id)	1999-12-09
TNSN98053A1 (fr)	2005-03-15
BG103828A (en)	2000-06-30
US6916927B2 (en)	2005-07-12
JP3563078B2 (ja)	2004-09-08
IL132276A (en)	2006-06-11
NO314585B1 (no)	2003-04-14
NO995211D0 (no)	1999-10-25
KR20010020285A (ko)	2001-03-15
KR100441229B1 (ko)	2004-07-22
JP2004196820A (ja)	2004-07-15
BR9810233A (pt)	2000-10-17
EA200100504A1 (ru)	2002-02-28
CN1253561A (zh)	2000-05-17
EA004315B1 (ru)	2004-02-26
JP4036836B2 (ja)	2008-01-23
HK1027808A1 (en)	2001-01-23
KR100390612B1 (ko)	2003-07-07
AU7644598A (en)	1998-11-24
PL336586A1 (en)	2000-07-03
MA24529A1 (fr)	1998-12-31
NO995211L (no)	1999-10-25
CN1188415C (zh)	2005-02-09
SK285991B6 (sk)	2008-01-07
IS5200A (is)	1999-09-28
RS50118B (sr)	2009-03-25
CA2288910C (en)	2003-06-24
EA199900866A1 (ru)	2000-04-24
US20040180944A1 (en)	2004-09-16
IL157646A (en)	2006-12-10
YU52499A (xx)	2002-08-12
TR199902646T2 (xx)	2000-05-22
JP2000510485A (ja)	2000-08-15
WO1998049166A1 (en)	1998-11-05
AP1002A (en)	2001-08-14

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DZ2394A1 (fr)	2003-06-04	Dérivés de quinoléine et dérivés de quinazoline nouveax procédé pour leur préparation et compositions pharmaceutiques les contenant
DZ2777A1 (fr)	2003-12-01	Dérivés de quinazolinamines nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.