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YU59100A - Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera - Google Patents

Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera

Info

Publication number
YU59100A
YU59100A YU59100A YUP59100A YU59100A YU 59100 A YU59100 A YU 59100A YU 59100 A YU59100 A YU 59100A YU P59100 A YUP59100 A YU P59100A YU 59100 A YU59100 A YU 59100A
Authority
YU
Yugoslavia
Prior art keywords
compounds
pyridylsulphonyl
pyrazolo
pyrimidin
intermediates
Prior art date
Application number
YU59100A
Other languages
English (en)
Inventor
Keith Michael Devries
Philip Charles Levett
Joanna Teresa Negri
Albert Shaw Wood
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9924042.6A external-priority patent/GB9924042D0/en
Priority claimed from GB0018667A external-priority patent/GB0018667D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU59100A publication Critical patent/YU59100A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Obezbedjen je postupak za dobijanje jedinjenja formule (I) koji obuhvata reagovanje jedinjenja formule (II), (III) ili (IV) u prisustvu OR i agensa za hvatanje hidroksida ili u slučaju jedinjenja formule (IV) reagovanje u prisustvu pomoćne baze i agensa za hvatanje hidroksida (tj OR je supstituisan pomoću pomoćne baze), gde X je odlazeća grupa i R1 do R4 su kao što je definisano napred.[Process has been secured for obtaining compounds of formula (I) encompassing the reactions of the compounds of formula (II), (III) or (IV) in the presence of OR and agents for the capturing of hydroxides or in the case compounds of formula (IV) encompassing the reactions of the bases and agents for the capturing of hydroxides (i.e. OR is substituted by means of auxilliary base), where x is the outgoing group and R1 to R4 are as previously defined.
YU59100A 1999-10-11 2000-09-29 Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera YU59100A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9924042.6A GB9924042D0 (en) 1999-10-11 1999-10-11 Process for thr preparation of pyrazolo[4,3-D]pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof
GB0018667A GB0018667D0 (en) 2000-07-28 2000-07-28 Process for the preparation of pyrazolo [4,3-d] Pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
YU59100A true YU59100A (sh) 2003-10-31

Family

ID=26244761

Family Applications (1)

Application Number Title Priority Date Filing Date
YU59100A YU59100A (sh) 1999-10-11 2000-09-29 Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera

Country Status (39)

Country Link
EP (1) EP1092720B1 (sh)
JP (1) JP2001114783A (sh)
KR (1) KR100395718B1 (sh)
CN (1) CN1292379A (sh)
AR (1) AR029767A1 (sh)
AT (1) ATE286899T1 (sh)
AU (1) AU6543600A (sh)
BG (1) BG104840A (sh)
BR (1) BR0004787A (sh)
CA (1) CA2322995A1 (sh)
CO (1) CO5251476A1 (sh)
CZ (1) CZ20003754A3 (sh)
DE (1) DE60017330D1 (sh)
DZ (1) DZ3096A1 (sh)
EA (1) EA003145B1 (sh)
EE (1) EE200000537A (sh)
EG (1) EG22775A (sh)
GT (1) GT200000169A (sh)
HR (1) HRP20000674A2 (sh)
HU (1) HUP0003979A3 (sh)
ID (1) ID27539A (sh)
IL (1) IL138913A0 (sh)
IN (1) IN190477B (sh)
IS (1) IS5654A (sh)
MA (1) MA25867A1 (sh)
MX (1) MXPA00009936A (sh)
NO (1) NO316072B1 (sh)
NZ (1) NZ507431A (sh)
OA (1) OA11495A (sh)
PA (1) PA8504601A1 (sh)
PE (1) PE20010682A1 (sh)
PL (1) PL343140A1 (sh)
SG (1) SG97950A1 (sh)
SK (1) SK15052000A3 (sh)
SV (1) SV2002000194A (sh)
TN (1) TNSN00195A1 (sh)
TR (1) TR200002959A2 (sh)
UY (1) UY26388A1 (sh)
YU (1) YU59100A (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI265925B (en) 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera
US6809200B2 (en) * 2000-07-28 2004-10-26 Pfizer Inc. Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof
JP2006219373A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
ES2343141T3 (es) * 2005-11-16 2010-07-23 F. Hoffmann-La Roche Ag Nuevo procedimiento para la preparacion de thoc.
KR101002490B1 (ko) * 2007-06-09 2010-12-17 동아제약주식회사 유데나필을 유효성분으로 함유하는 만성 심부전증 치료용약학적 조성물
JP5543039B2 (ja) * 2011-02-23 2014-07-09 ファイザー・インク 神経障害治療のためのイミダゾ［５，１−ｆ］［１，２，４］トリアジン
CA3044164A1 (en) * 2016-11-21 2018-05-24 Adama Agan Ltd. Process for preparing methoxy methyl pyridine dicarboxylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL336586A1 (en) * 1997-04-25 2000-07-03 Pfizer Pyrazoylpyrimidinones inhibiting the cyclic guanosine 3',5'-monophosphate phosphodiesterase of type 5 (cgmp pde5) for treating sexual disorders
HUP0102543A3 (en) * 1998-04-20 2002-01-28 Pfizer Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera

Also Published As

Publication number Publication date
BR0004787A (pt) 2001-05-22
KR20010050935A (ko) 2001-06-25
KR100395718B1 (ko) 2003-08-25
PE20010682A1 (es) 2001-07-04
EA200000924A2 (ru) 2001-04-23
AU6543600A (en) 2001-04-12
DE60017330D1 (de) 2005-02-17
HUP0003979A3 (en) 2002-03-28
EE200000537A (et) 2001-06-15
EA003145B1 (ru) 2003-02-27
NO20005104D0 (no) 2000-10-10
IS5654A (is) 2001-04-12
HU0003979D0 (en) 2000-12-28
MA25867A1 (fr) 2003-10-01
NO316072B1 (no) 2003-12-08
EG22775A (en) 2003-08-31
HRP20000674A2 (en) 2001-08-31
DZ3096A1 (fr) 2004-06-20
IL138913A0 (en) 2001-11-25
EP1092720A2 (en) 2001-04-18
PA8504601A1 (es) 2002-02-21
EP1092720B1 (en) 2005-01-12
EP1092720A3 (en) 2001-09-19
IN190477B (sh) 2003-08-02
CZ20003754A3 (cs) 2002-06-12
BG104840A (bg) 2001-10-31
JP2001114783A (ja) 2001-04-24
EA200000924A3 (ru) 2001-06-25
NO20005104L (no) 2001-04-17
TR200002959A2 (tr) 2001-07-23
NZ507431A (en) 2002-09-27
GT200000169A (es) 2002-04-03
CA2322995A1 (en) 2001-04-11
ATE286899T1 (de) 2005-01-15
OA11495A (en) 2004-05-05
PL343140A1 (en) 2001-04-23
ID27539A (id) 2001-04-12
TNSN00195A1 (fr) 2005-11-10
CO5251476A1 (es) 2003-02-28
UY26388A1 (es) 2001-05-31
SK15052000A3 (sk) 2003-01-09
SV2002000194A (es) 2002-01-23
SG97950A1 (en) 2003-08-20
MXPA00009936A (es) 2002-10-23
AR029767A1 (es) 2003-07-16
HUP0003979A2 (hu) 2001-12-28
CN1292379A (zh) 2001-04-25

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