DZ2141A1 - Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine. - Google Patents

Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine.

Info

Publication number: DZ2141A1
Authority: DZ; Algeria
Prior art keywords: indanone; methylpiperidine; dimethoxy; benzyl; preparation
Prior art date: 1995-12-15

Application number

DZ960186A

Other languages

English (en)

Inventor

Keith M Devries

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-15

Filing date

1996-12-11

Publication date

2002-07-23

1996-12-11 Application filed by Pfizer filed Critical Pfizer

2002-07-23 Application granted granted Critical

2002-07-23 Publication of DZ2141A1 publication Critical patent/DZ2141A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

DZ960186A 1995-12-15 1996-12-11 Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine. DZ2141A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US875395P	1995-12-15	1995-12-15

Publications (1)

Publication Number	Publication Date
DZ2141A1 true DZ2141A1 (fr)	2002-07-23

Family

ID=21733469

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ960186A DZ2141A1 (fr)	1995-12-15	1996-12-11	Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine.

Country Status (33)

Country	Link
EP (1)	EP0883607A1 (fr)
JP (1)	JP3066083B2 (fr)
KR (1)	KR20000064387A (fr)
AP (1)	AP708A (fr)
AR (1)	AR004368A1 (fr)
AU (1)	AU716462B2 (fr)
BG (1)	BG102525A (fr)
BR (1)	BR9612018A (fr)
CA (1)	CA2237647A1 (fr)
CO (1)	CO4750831A1 (fr)
CZ (1)	CZ180898A3 (fr)
DZ (1)	DZ2141A1 (fr)
GT (1)	GT199600092A (fr)
HN (1)	HN1996000065A (fr)
HR (1)	HRP960592A2 (fr)
HU (1)	HUP9904275A3 (fr)
IL (3)	IL136420A0 (fr)
IS (1)	IS4752A (fr)
MA (1)	MA24032A1 (fr)
NO (1)	NO982712L (fr)
NZ (1)	NZ318843A (fr)
OA (1)	OA10694A (fr)
PE (1)	PE25698A1 (fr)
PL (1)	PL197306B1 (fr)
RO (1)	RO121382B1 (fr)
RU (1)	RU2160731C2 (fr)
SK (1)	SK75498A3 (fr)
TN (1)	TNSN96153A1 (fr)
TW (1)	TW414787B (fr)
UY (1)	UY24401A1 (fr)
WO (1)	WO1997022584A1 (fr)
YU (1)	YU49486B (fr)
ZA (1)	ZA9610533B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE292116T1 (de)	1998-01-16	2005-04-15	Eisai Co Ltd	Verfahren zur herstellung von donepezilderivaten
IL125809A (en) *	1998-08-17	2005-08-31	Finetech Lab Ltd	Process and intermediates for production of donepezil and related compounds
US7148354B2 (en) *	2002-07-24	2006-12-12	Dr. Reddy's Laboratories Limited	Process for preparation of donepezil
IL150982A (en)	2002-07-30	2007-02-11	Ori Lerman	Process for making Donafzil
IL151253A0 (en) *	2002-08-14	2003-04-10	Finetech Lab Ltd	Process for production of highly pure donepezil hydrochloride
US6649765B1 (en)	2003-02-12	2003-11-18	Usv Limited, Bsd Marg.	Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)
US6953856B2 (en)	2003-02-12	2005-10-11	Usv, Limited	Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)
US20070129549A1 (en) *	2003-03-21	2007-06-07	Yatendra Kumar	Stable lamotrigine pharmaceutical compositions and processes for their preparation
WO2004099142A1 (fr) *	2003-05-05	2004-11-18	Ranbaxy Laboratories Limited	Sel de bromhydrate de benzyl-piperidylmethyl-indanone et ses polymorphes
EP1654230A1 (fr)	2003-07-01	2006-05-10	Hetero Drugs Limited	Preparation d'intermediaires pour inhibiteurs de l'acetyl cholinesterase
CN1280273C (zh)	2003-11-05	2006-10-18	天津和美生物技术有限公司	合成多奈哌齐及其衍生物的方法
WO2006035433A2 (fr)	2004-09-29	2006-04-06	Chemagis Ltd.	Utilisation de maleate de donepezil purifie pour preparer un hydrochlorure de donepezil amorphe pharmaceutiquement pur
CN100436416C (zh) *	2005-07-29	2008-11-26	西南合成制药股份有限公司	盐酸多奈哌齐合成工艺
GB0515803D0 (en)	2005-07-30	2005-09-07	Pliva Hrvatska D O O	Intermediate compounds
AR057910A1 (es)	2005-11-18	2007-12-26	Synthon Bv	Proceso para preparar donepezilo
KR20080085195A (ko) *	2006-01-04	2008-09-23	씨아이피엘에이 엘티디.	도네페질의 제조방법 및 중간체
EP2114166A4 (fr)	2006-12-11	2011-05-25	Reviva Pharmaceuticals Inc	Compositions, synthèse et procédés d'utilisation d'inhibiteurs de cholinestérase à base d'indanone
WO2013078608A1 (fr)	2011-11-29	2013-06-06	Ziqiang Gu	Pamoate de donepezil et ses procédés de fabrication et d'utilisation
US10357486B2 (en)	2013-08-16	2019-07-23	Universiteit Maastricht	Treatment of cognitive impairment with PDE4 inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI95572C (fi) *	1987-06-22	1996-02-26	Eisai Co Ltd	Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
FR2642069B1 (fr) *	1989-01-20	1991-04-12	Rhone Poulenc Sante	Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent
DE4439822A1 (de) *	1994-11-08	1996-08-29	Bayer Ag	Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen

1996
- 1996-10-11 RU RU98111204/04A patent/RU2160731C2/ru not_active IP Right Cessation
- 1996-10-11 RO RO98-01070A patent/RO121382B1/ro unknown
- 1996-10-11 CA CA002237647A patent/CA2237647A1/fr not_active Abandoned
- 1996-10-11 HU HU9904275A patent/HUP9904275A3/hu unknown
- 1996-10-11 CZ CZ981808A patent/CZ180898A3/cs unknown
- 1996-10-11 SK SK754-98A patent/SK75498A3/sk unknown
- 1996-10-11 AU AU70925/96A patent/AU716462B2/en not_active Ceased
- 1996-10-11 IL IL13642096A patent/IL136420A0/xx unknown
- 1996-10-11 NZ NZ318843A patent/NZ318843A/xx unknown
- 1996-10-11 BR BR9612018A patent/BR9612018A/pt not_active Application Discontinuation
- 1996-10-11 JP JP9522607A patent/JP3066083B2/ja not_active Expired - Lifetime
- 1996-10-11 EP EP96931937A patent/EP0883607A1/fr not_active Withdrawn
- 1996-10-11 IL IL12445296A patent/IL124452A0/xx unknown
- 1996-10-11 WO PCT/IB1996/001076 patent/WO1997022584A1/fr not_active Ceased
- 1996-10-11 IL IL13642196A patent/IL136421A0/xx unknown
- 1996-10-11 PL PL327512A patent/PL197306B1/pl not_active IP Right Cessation
- 1996-10-11 KR KR1019980704423A patent/KR20000064387A/ko not_active Ceased
- 1996-10-14 TW TW085112515A patent/TW414787B/zh not_active IP Right Cessation
- 1996-10-15 HN HN1996000065A patent/HN1996000065A/es unknown
- 1996-11-18 GT GT199600092A patent/GT199600092A/es unknown
- 1996-12-09 PE PE1996000883A patent/PE25698A1/es not_active Application Discontinuation
- 1996-12-10 AR ARP960105577A patent/AR004368A1/es unknown
- 1996-12-11 YU YU66096A patent/YU49486B/sh unknown
- 1996-12-11 TN TNTNSN96153A patent/TNSN96153A1/fr unknown
- 1996-12-11 MA MA24424A patent/MA24032A1/fr unknown
- 1996-12-11 DZ DZ960186A patent/DZ2141A1/fr active
- 1996-12-12 CO CO96065334A patent/CO4750831A1/es unknown
- 1996-12-12 AP APAP/P/1996/000892A patent/AP708A/en active
- 1996-12-12 UY UY24401A patent/UY24401A1/es not_active IP Right Cessation
- 1996-12-13 HR HR60/008,753A patent/HRP960592A2/xx not_active Application Discontinuation
- 1996-12-13 ZA ZA9610533A patent/ZA9610533B/xx unknown
1998
- 1998-05-22 IS IS4752A patent/IS4752A/is unknown
- 1998-06-05 OA OA9800076A patent/OA10694A/en unknown
- 1998-06-09 BG BG102525A patent/BG102525A/xx unknown
- 1998-06-12 NO NO982712A patent/NO982712L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
RO121382B1 (ro)	2007-04-30
RU2160731C2 (ru)	2000-12-20
YU66096A (en)	1999-11-22
CO4750831A1 (es)	1999-03-31
YU49486B (sh)	2006-08-17
HUP9904275A3 (en)	2001-05-28
KR20000064387A (ko)	2000-11-06
BG102525A (en)	1999-05-31
IL136421A0 (en)	2001-06-14
NZ318843A (en)	2000-01-28
CZ180898A3 (cs)	1999-05-12
UY24401A1 (es)	1997-06-09
HRP960592A2 (en)	1998-06-30
AU716462B2 (en)	2000-02-24
BR9612018A (pt)	1999-02-17
WO1997022584A1 (fr)	1997-06-26
HUP9904275A2 (hu)	2000-05-28
AP9600892A0 (en)	1997-01-31
ZA9610533B (en)	1998-06-15
JP3066083B2 (ja)	2000-07-17
OA10694A (en)	2001-05-04
MX9804820A (es)	1998-10-31
PE25698A1 (es)	1998-05-21
IL136420A0 (en)	2001-06-14
JPH11500756A (ja)	1999-01-19
NO982712D0 (no)	1998-06-12
GT199600092A (es)	1998-05-12
CA2237647A1 (fr)	1997-06-26
AR004368A1 (es)	1998-11-04
PL327512A1 (en)	1998-12-21
IS4752A (is)	1998-05-22
AU7092596A (en)	1997-07-14
PL197306B1 (pl)	2008-03-31
NO982712L (no)	1998-06-12
AP708A (en)	1998-12-04
MA24032A1 (fr)	1997-07-01
HN1996000065A (es)	1997-06-26
EP0883607A1 (fr)	1998-12-16
IL124452A0 (en)	1998-12-06
SK75498A3 (en)	1999-08-06
TW414787B (en)	2000-12-11
TNSN96153A1 (fr)	2005-03-15

Publication	Publication Date	Title
DZ2141A1 (fr)	2002-07-23	Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine.
DZ2114A1 (fr)	2002-07-22	Procédé pour la préparation du d-tartrate de (-)-cis-6(s)-phényl-5}4-(2-pyrrolidine-1-ylethoxy)-phénylÜ-5,6,7,8-tétrahydronaphtalène-2-ol.
HU9603495D0 (en)	1997-02-28	1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-compounds, as pharmaceutical agents
ZA968957B (en)	1998-04-24	Process for the preparation of dihaloazolopyrimidines.
AU7360887A (en)	1987-12-10	Pharmacologically active 1,5-diarly-3-substituted- pyrazoles and method for synthesizing the same
NO981800L (no)	1998-06-11	FremgangsmÕte for fremstilling av 1,1,1,3,3-pentafluorpentan
DZ3079A1 (fr)	2004-10-24	Procédé pour la préparation de 4-carboxy-amino-2-substitué-1,2,3,4 tétrahydroquinolé.
DZ2032A1 (fr)	2002-07-21	Un procédé pour la préparation de l'hydrochlorure de lercanidipine.
ZA968081B (en)	1998-03-26	Pharmaceutical composition.
MA23134A1 (fr)	1994-10-01	Procede pour la preparation d'aryl-piperidine carbinols .
HUP0100640A3 (en)	2001-11-28	Process for the preparation of 1,4-dihydropyridines
ZA961884B (en)	1997-09-09	Novel naphthyl pharmaceutical compounds.
EP0657438A3 (fr)	1995-10-11	Procédé pour la préparation d'alkylesulfinylbenzamides et de 1,2-benzoisothiazol-3-ones.
AU4729396A (en)	1996-10-08	Process for the preparation of 1,2-benzisothiazolin-3-ones
FR2733227B1 (fr)	1997-07-04	Procede pour la preparation de 1,1-difluoroethane
FI974435A7 (fi)	1997-12-05	Menetelmä 2,4-diklooripyridiinien muuttamiseksi 2-aryylioksi-4-kloorip yridiineiksi
NO985535L (no)	1999-01-27	FremgangsmÕte for fremstilling av 1,3-alkandioler
EP0648784A3 (fr)	1995-08-16	Procédé de préparation de polymères téléchéliques.
EP0636611A3 (en)	1995-03-01	Optically active 1,4-dihydropyridine derivatives and process for preparing the same.
ZA966347B (en)	1997-02-11	Process for the preparation of 1,4-butenediol.
IL118731A (en)	2000-07-16	Process for the preparation of 2,2-dialkyl-arylidenecycloalkanones
ZA991215B (en)	1999-08-16	Process for the preparation of 1,3-disubstituted 2-nitroguanidines.
ZA966542B (en)	1998-02-02	Process for the preparation of 3,3,5-trichloroglutarimide.
FR2736635B1 (fr)	1997-08-14	Procede de preparation d'alpha,omega-bromochloroalcanes
FI970039A7 (fi)	1997-01-03	Menetelmä 5-aryyli-2,4-dialkyyli-3H-1,2,3-triatsoli-3-tionien valmista miseksi