[go: up one dir, main page]

DK45591A - 5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner - Google Patents

5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner Download PDF

Info

Publication number
DK45591A
DK45591A DK045591A DK45591A DK45591A DK 45591 A DK45591 A DK 45591A DK 045591 A DK045591 A DK 045591A DK 45591 A DK45591 A DK 45591A DK 45591 A DK45591 A DK 45591A
Authority
DK
Denmark
Prior art keywords
alkyl
5beta
phenyl
substd
onhylided
Prior art date
Application number
DK045591A
Other languages
English (en)
Other versions
DK175696B1 (da
DK45591D0 (da
Inventor
Steven J Brickner
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK45591D0 publication Critical patent/DK45591D0/da
Publication of DK45591A publication Critical patent/DK45591A/da
Priority to DK200401246A priority Critical patent/DK175940B1/da
Application granted granted Critical
Publication of DK175696B1 publication Critical patent/DK175696B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK199100455A 1988-09-15 1991-03-13 5'-Indolinyloxazolidin-2-oner med farmaceutisk acceptable salte deraf DK175696B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US24498888A 1988-09-15 1988-09-15
US24498888 1988-09-15
US25385088A 1988-10-05 1988-10-05
US25385088 1988-10-05
US32494289A 1989-03-17 1989-03-17
US32494289 1989-03-17
PCT/US1989/003548 WO1990002744A1 (en) 1988-09-15 1989-08-22 In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
US8903548 1989-08-22

Publications (3)

Publication Number Publication Date
DK45591D0 DK45591D0 (da) 1991-03-13
DK45591A true DK45591A (da) 1991-03-13
DK175696B1 DK175696B1 (da) 2005-01-24

Family

ID=27399816

Family Applications (2)

Application Number Title Priority Date Filing Date
DK199100455A DK175696B1 (da) 1988-09-15 1991-03-13 5'-Indolinyloxazolidin-2-oner med farmaceutisk acceptable salte deraf
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200401246A DK175940B1 (da) 1988-09-15 2004-08-18 3-(Nitrogensubstituerede)-phenyl-5beta-aminomethyloxazolidin-2-oner og farmaceutisk acceptable salte deraf samt anvendelse af disse forbindelser til fremstilling af et lægemiddel

Country Status (13)

Country Link
EP (3) EP0609905B1 (da)
JP (2) JP2865211B2 (da)
KR (1) KR0138262B1 (da)
AT (2) ATE112773T1 (da)
AU (1) AU617871B2 (da)
CA (1) CA1335103C (da)
DE (2) DE68918792T2 (da)
DK (2) DK175696B1 (da)
ES (1) ES2157934T3 (da)
GR (1) GR3036491T3 (da)
LV (1) LV12888B (da)
TW (1) TW219936B (da)
WO (1) WO1990002744A1 (da)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
AU646871B2 (en) * 1990-06-07 1994-03-10 Astrazeneca Uk Limited Therapeutic heterocyclic compounds
PL171280B1 (pl) * 1991-08-14 1997-03-28 Procter & Gamble Pharma Sposób wytwarzania nowych cyklicznych uretanów PL PL
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
WO1994001110A1 (en) * 1992-07-08 1994-01-20 The Upjohn Company 5'-INDOLINYL OXAZOLIDINONES USEFUL AGAINST $i(MYCOBACTERIUM TUBERCULOSIS)
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
DK0788498T3 (da) * 1994-10-26 2001-11-05 Upjohn Co Phenyloxazolidinoner med antimikrobiel virkning
JPH10508844A (ja) * 1994-11-15 1998-09-02 ファルマシア・アンド・アップジョン・カンパニー 二環式オキサジンおよびチアジンオキサゾリジノン抗菌剤
EP0807112B1 (en) * 1995-02-03 2001-09-05 PHARMACIA & UPJOHN COMPANY Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
PT828741E (pt) * 1995-05-11 2002-02-28 Upjohn Co Oxazolidinonas de diazinilo espirociclico e biciclico e de carbazinilo
MX9703040A (es) * 1995-09-12 1997-07-31 Upjohn Co Antimicrobianos de feniloxazolidinona.
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
DE19601264A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601265A1 (de) 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
KR20010013192A (ko) * 1997-05-30 2001-02-26 로렌스 티. 마이젠헬더 티오카보닐 작용기를 갖는 옥사졸리디논 항균제
DE19730847A1 (de) * 1997-07-18 1999-01-28 Bayer Ag Tricyclisch substituierte Oxazolidinone
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
BR9813985A (pt) * 1997-11-12 2000-09-26 Upjohn Co Derivados de oxazolidinona e composições farmacêuticas
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
CN1288462A (zh) * 1998-01-23 2001-03-21 法玛西雅厄普约翰美国公司 噁唑烷酮组合库、组合物和制备方法
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU767380B2 (en) * 1999-05-27 2003-11-06 Pharmacia & Upjohn Company Bicyclic oxazolidinones as antibacterial agent
AU773359B2 (en) 1999-07-28 2004-05-20 Pharmacia & Upjohn Company Oxazolidinones and their use as antiinfectives
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
JP2004504321A (ja) 2000-07-17 2004-02-12 ランバクシー　ラボラトリーズ　リミテッド 抗微生物剤としてのオキサゾリジノン誘導体
US6777441B2 (en) 2000-10-02 2004-08-17 Emory University Triptolide analogs for the treatment of autoimmune and inflammatory disorders
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
WO2006016221A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxazolidinones containing oxindoles as antibacterial agents
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
KR20070116989A (ko) * 2005-04-06 2007-12-11 파마시아 앤드 업존 캄파니 엘엘씨 항균제로서의 옥신돌 옥사졸리디논
NZ585752A (en) * 2007-12-24 2011-11-25 Cipla Ltd Process for the synthesis of propargylated aminoindan derivatives
CA2794153C (en) 2010-03-25 2018-01-02 Glaxosmithkline Llc Substituted indoline derivatives as perk inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
LV12888B (en) 2002-12-20
KR0138262B1 (ko) 1998-05-15
ATE201870T1 (de) 2001-06-15
DE68929303D1 (de) 2001-07-12
DE68929303T2 (de) 2002-05-02
EP0359418A1 (en) 1990-03-21
DK175940B1 (da) 2005-08-01
TW219936B (da) 1994-02-01
JP2865211B2 (ja) 1999-03-08
AU617871B2 (en) 1991-12-05
EP0359418B1 (en) 1994-10-12
CA1335103C (en) 1995-04-04
EP0609905B1 (en) 2001-06-06
JPH04500665A (ja) 1992-02-06
DK175696B1 (da) 2005-01-24
JP3188418B2 (ja) 2001-07-16
HK1002234A1 (en) 1998-08-07
GR3036491T3 (en) 2001-11-30
DK45591D0 (da) 1991-03-13
DE68918792D1 (de) 1994-11-17
WO1990002744A1 (en) 1990-03-22
KR900701780A (ko) 1990-12-04
DK200401246A (da) 2004-08-18
ATE112773T1 (de) 1994-10-15
EP0609905A1 (en) 1994-08-10
DE68918792T2 (de) 1995-03-30
AU4195789A (en) 1990-04-02
JPH1180139A (ja) 1999-03-26
EP0434714A1 (en) 1991-07-03
ES2157934T3 (es) 2001-09-01

Similar Documents

Publication Publication Date Title
DK45591D0 (da) 5'-indolinyl-5beta-amidomethyloxazolidin-2-oner, 3-(kondenseret ring-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner og 3-(nitrogen-substituerede)-phenyl-5beta-amidomethyloxazolidin-2-oner
SE8603966L (sv) Fluoroaluminosilikatglaspulver for dentalglasjonomercement
NO820264L (no) Fremgangsmaate for fremstilling av 2-penemforbindelser
DK0791571T3 (da) Benzoylderivater
HUT51863A (da)
ES476682A1 (es) Un procedimiento para la preparacion de nuevos dericados de 1-aza-biciclo (2,2,2)octano, utiles como psicotrupos.
GR3003327T3 (en) Substituted 1,8-naphthyridine derivatives and fungicides containing them
DE69015471D1 (de) 1-Benzhydrylazetidine, deren Herstellung und Verwendung als Zwischenprodukte zur Herstellung von Verbindungen mit antimikrobieller Wirkung.
DE59003309D1 (de) Monoklines Metazachlor und Verfahren zu seiner Herstellung.
PT79969B (de) Isoxazol-derivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IE792418L (en) Diazines.
EP0319689A3 (en) N-sultam-sulfon amides substituted by a heterocyclic ring, process for their preparation and their use as herbicides and as plant growth regulators
ES2095933T3 (es) Cepillo de dientes.
DE69223362D1 (de) N1-Trifluoralkyl substituierte 2-Nitro-p-Phenylendiaminfarbstoffe
ES2037825T3 (es) Uso farmaceutico de tioeteres aromaticos.
ES8707960A1 (es) Procedimiento para la obtencion de derivados de triazolo- (3,2-c)perhidroxazin-8-ona
GB2013654A (en) 3-Amino-1,2-Benzoisothiazole 1,1-Dioxides
DK0483063T3 (da) Ergolinderivater
ZA873224B (en) 3-amino-dihydropyridines,a process for their preparation,and their use in medicaments
ES1008666U (es) Cepillo para limpieza dental con portasedas.
DK4579A (da) Tandboerste
JPS6450807A (en) Photo-polymerizable dental material

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK