DK3778621T3 - Peptidsyntesefremgangsmåde - Google Patents
Peptidsyntesefremgangsmåde Download PDFInfo
- Publication number
- DK3778621T3 DK3778621T3 DK19785772.5T DK19785772T DK3778621T3 DK 3778621 T3 DK3778621 T3 DK 3778621T3 DK 19785772 T DK19785772 T DK 19785772T DK 3778621 T3 DK3778621 T3 DK 3778621T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide synthesis
- synthesis procedure
- procedure
- peptide
- synthesis
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000010647 peptide synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018077501 | 2018-04-13 | ||
| PCT/JP2019/016068 WO2019198833A1 (ja) | 2018-04-13 | 2019-04-13 | ペプチド合成方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3778621T3 true DK3778621T3 (da) | 2023-09-25 |
| DK3778621T5 DK3778621T5 (da) | 2024-08-19 |
Family
ID=68164275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19785772.5T DK3778621T5 (da) | 2018-04-13 | 2019-04-13 | Peptidsyntesefremgangsmåde |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11420997B2 (da) |
| EP (1) | EP3778621B1 (da) |
| JP (1) | JP6703668B2 (da) |
| CN (1) | CN111971293B (da) |
| DK (1) | DK3778621T5 (da) |
| ES (1) | ES2957399T3 (da) |
| WO (1) | WO2019198833A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12024537B2 (en) | 2018-05-31 | 2024-07-02 | Sederma | Compositions and methods for chemical synthesis |
| CA3126705A1 (en) | 2019-02-01 | 2020-08-06 | Gap Peptides Llc | Synthesis strategy for gap protecting group |
| CN110256277B (zh) * | 2019-03-19 | 2020-12-15 | 广州同隽医药科技有限公司 | 一种含有芴环结构的化合物及其应用 |
| JP7661880B2 (ja) | 2019-04-25 | 2025-04-15 | 味の素株式会社 | ペプチドの連続的製造方法 |
| CN110981746B (zh) * | 2019-12-23 | 2024-07-12 | 盐城通海生物科技有限公司 | 一种c5侧链取代的含氟二胺单体的制备方法 |
| JP7709920B2 (ja) * | 2019-12-27 | 2025-07-17 | 中外製薬株式会社 | ペプチド化合物の合成法 |
| AU2022239717A1 (en) | 2021-03-15 | 2023-11-02 | Maze Therapeutics, Inc. | Inhibitors of glycogen synthase 1 (gys1) and methods of use thereof |
| JP7162853B1 (ja) * | 2021-07-02 | 2022-10-31 | ペプチスター株式会社 | 液相ペプチド合成用担体結合ペプチドの分析方法 |
| JP7154513B1 (ja) | 2021-07-02 | 2022-10-18 | ペプチスター株式会社 | 液相ペプチド製造方法 |
| JP7063408B1 (ja) | 2021-07-02 | 2022-05-09 | ペプチスター株式会社 | 液相ペプチド製造方法 |
| JP2025001050A (ja) * | 2021-09-01 | 2025-01-08 | 積水メディカル株式会社 | ガニレリクス又はその塩の製造法 |
| EP4201951B1 (en) | 2021-12-21 | 2023-11-22 | Bachem Holding AG | Method for peptide synthesis |
| JP7260725B1 (ja) * | 2021-12-27 | 2023-04-18 | 株式会社トクヤマ | ペプチド製造方法、保護基の除去方法、及び除去剤 |
| WO2023127331A1 (ja) * | 2021-12-27 | 2023-07-06 | 株式会社トクヤマ | ペプチド製造方法、保護基の除去方法、除去剤、及びベンジル化合物 |
| CN114276222B (zh) * | 2021-12-31 | 2024-04-09 | 杭州澳赛诺生物科技有限公司 | 一种作为多肽液相合成载体的二芳基苯甲醇类化合物及其制备方法与应用 |
| JP7651094B2 (ja) * | 2022-01-17 | 2025-03-26 | 学校法人中部大学 | ペプチド化合物の製造方法 |
| CN120457138A (zh) * | 2023-01-13 | 2025-08-08 | 株式会社德山 | 含氨基化合物的制造方法、含氨基化合物的分离方法以及含氨基化合物的制造装置 |
| WO2024150477A1 (ja) * | 2023-01-13 | 2024-07-18 | 株式会社トクヤマ | アミノ基含有化合物の製造方法、アミノ基含有化合物の分離方法、およびアミノ基含有化合物の製造装置 |
| WO2025229967A1 (ja) * | 2024-04-30 | 2025-11-06 | 富士フイルム株式会社 | ペプチドの製造方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2849776C2 (de) | 1978-11-16 | 1986-05-15 | Gewerkschaft Eisenhütte Westfalia, 4670 Lünen | Messerschild |
| JPS6116973A (ja) | 1985-04-04 | 1986-01-24 | Showa Electric Wire & Cable Co Ltd | 耐熱性絶縁電線 |
| US5516891A (en) * | 1992-06-16 | 1996-05-14 | Kinerton, Ltd. | Liquid phase synthesis of peptides and peptide derivatives |
| IL150601A (en) | 2001-07-19 | 2010-06-30 | Organon Nv | Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component |
| EP1426101B1 (en) | 2001-08-24 | 2011-01-05 | Japan Science and Technology Agency | Compatible-multiphase organic solvent system |
| JP4283469B2 (ja) | 2001-12-19 | 2009-06-24 | 独立行政法人科学技術振興機構 | 相溶性−多相有機溶媒システムによりアミノ酸を逐次的に付加する液相ペプチド合成法 |
| JP2004059509A (ja) | 2002-07-30 | 2004-02-26 | Nokodai Tlo Kk | 液相ペプチド合成用アミノ酸試薬 |
| DK1927584T3 (da) | 2005-09-20 | 2017-02-20 | Jitsubo Co Ltd | Bærer til separation, fremgangsmåde til separation af forbindelse og fremgangsmåde til syntese af peptid under anvendelse af bæreren |
| US8314208B2 (en) | 2006-02-10 | 2012-11-20 | Cem Corporation | Microwave enhanced N-fmoc deprotection in peptide synthesis |
| US8716439B2 (en) | 2006-03-01 | 2014-05-06 | Kaneka Corporation | Method of producing peptide |
| JPWO2007122847A1 (ja) | 2006-03-24 | 2009-09-03 | Jitsubo株式会社 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
| EP2322498B1 (en) | 2008-08-06 | 2014-04-16 | Ajinomoto Co., Inc. | Processes for removing dibenzofulvene |
| US8569453B2 (en) | 2009-03-12 | 2013-10-29 | Ajinomoto Co., Inc. | Fluorene compound |
| US8722934B2 (en) | 2009-03-30 | 2014-05-13 | Ajinomoto Co., Inc. | Diphenylmethane compound |
| JP5803674B2 (ja) * | 2009-12-25 | 2015-11-04 | 味の素株式会社 | ベンジル化合物 |
| US8546534B2 (en) | 2010-08-30 | 2013-10-01 | Ajinomoto Co., Inc. | Branched chain-containing aromatic compound |
| EP2716650A1 (en) | 2011-05-31 | 2014-04-09 | Ajinomoto Co., Inc. | Method for producing peptide |
| US9635577B2 (en) | 2011-12-12 | 2017-04-25 | Lg Electronics Inc. | Method and device for measuring a reference signal received quality in wireless communication system |
| JP6136934B2 (ja) | 2011-12-15 | 2017-05-31 | 味の素株式会社 | Ｆｍｏｃ基の除去方法 |
| JP6713983B2 (ja) * | 2015-03-04 | 2020-06-24 | Jitsubo株式会社 | ペプチド合成方法 |
| WO2017038650A1 (ja) | 2015-08-28 | 2017-03-09 | 積水メディカル株式会社 | ベンジル化合物 |
| WO2017221889A1 (ja) | 2016-06-20 | 2017-12-28 | 積水メディカル株式会社 | 新規ジフェニルメタン保護剤 |
-
2019
- 2019-04-13 DK DK19785772.5T patent/DK3778621T5/da active
- 2019-04-13 ES ES19785772T patent/ES2957399T3/es active Active
- 2019-04-13 US US17/046,682 patent/US11420997B2/en active Active
- 2019-04-13 CN CN201980025310.XA patent/CN111971293B/zh active Active
- 2019-04-13 WO PCT/JP2019/016068 patent/WO2019198833A1/ja not_active Ceased
- 2019-04-13 EP EP19785772.5A patent/EP3778621B1/en active Active
- 2019-04-13 JP JP2019548081A patent/JP6703668B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3778621A1 (en) | 2021-02-17 |
| JPWO2019198833A1 (ja) | 2020-04-30 |
| ES2957399T3 (es) | 2024-01-18 |
| EP3778621B1 (en) | 2023-08-23 |
| CN111971293A (zh) | 2020-11-20 |
| US20210139532A1 (en) | 2021-05-13 |
| JP6703668B2 (ja) | 2020-06-03 |
| CN111971293B (zh) | 2024-07-30 |
| US11420997B2 (en) | 2022-08-23 |
| EP3778621A4 (en) | 2021-06-30 |
| WO2019198833A1 (ja) | 2019-10-17 |
| DK3778621T5 (da) | 2024-08-19 |
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