DK3748340T3 - Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme - Google Patents
Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme Download PDFInfo
- Publication number
- DK3748340T3 DK3748340T3 DK20188814.6T DK20188814T DK3748340T3 DK 3748340 T3 DK3748340 T3 DK 3748340T3 DK 20188814 T DK20188814 T DK 20188814T DK 3748340 T3 DK3748340 T3 DK 3748340T3
- Authority
- DK
- Denmark
- Prior art keywords
- glicosyled
- glicosylamins
- biomolecules
- labeled
- procedures
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/98—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072747P | 2014-10-30 | 2014-10-30 | |
| US201562107994P | 2015-01-26 | 2015-01-26 | |
| EP15855907.0A EP3213056B1 (en) | 2014-10-30 | 2015-10-28 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3748340T3 true DK3748340T3 (da) | 2022-04-19 |
Family
ID=55858312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15855907.0T DK3213056T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund |
| DK20188814.6T DK3748340T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15855907.0T DK3213056T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11371996B2 (da) |
| EP (3) | EP3748340B1 (da) |
| JP (3) | JP7055634B2 (da) |
| CN (2) | CN115753702A (da) |
| DK (2) | DK3213056T3 (da) |
| WO (1) | WO2016069764A1 (da) |
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| EP3309549B1 (en) | 2011-09-28 | 2021-11-10 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced ms signals |
| US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| JP7055634B2 (ja) | 2014-10-30 | 2022-04-18 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 標識化グリコシルアミンの迅速調製およびそれを生成するグリコシル化生体分子の分析方法 |
| US10502720B2 (en) | 2014-11-13 | 2019-12-10 | Waters Technologies Corporation | Methods for liquid chromatography calibration for rapid labeled N-glycans |
| CN109640994A (zh) * | 2016-06-21 | 2019-04-16 | 沃特世科技公司 | 增强被标记的聚糖的ms检测的方法 |
| WO2017222955A1 (en) | 2016-06-21 | 2017-12-28 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
| CN109641846A (zh) | 2016-06-21 | 2019-04-16 | 沃特世科技公司 | 通过用于增强的ms信号的还原胺化的聚糖和其他生物分子的荧光标记 |
| EP3479103B1 (en) | 2016-07-01 | 2022-04-20 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
| EP3491374B1 (en) * | 2016-07-28 | 2024-10-09 | Waters Technologies Corporation | Encapsulated pre-analytic workflow reagents for flow-through devices, liquid chromatography and mass spectrometric analysis |
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| JP7247099B2 (ja) * | 2017-03-31 | 2023-03-28 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | ヒト血清または尿におけるalxn1210およびエクリズマブの同時定量のための方法 |
| CN109254101B (zh) * | 2017-07-13 | 2021-07-09 | 中国科学院大连化学物理研究所 | 一种母乳酸性寡糖净化和分析方法 |
| CN118225957A (zh) * | 2018-03-16 | 2024-06-21 | 奎斯特诊断投资有限公司 | 通过质谱检测嗜铬粒蛋白a的方法 |
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2015
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- 2015-10-28 EP EP20188814.6A patent/EP3748340B1/en active Active
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| JP7055634B2 (ja) | 2022-04-18 |
| US20220268779A1 (en) | 2022-08-25 |
| JP7687847B2 (ja) | 2025-06-03 |
| US11371996B2 (en) | 2022-06-28 |
| EP3748340A1 (en) | 2020-12-09 |
| EP3748340B1 (en) | 2022-04-06 |
| EP4033223B1 (en) | 2025-06-18 |
| US20180188259A1 (en) | 2018-07-05 |
| JP2018501465A (ja) | 2018-01-18 |
| EP3213056A4 (en) | 2018-08-08 |
| JP7716450B2 (ja) | 2025-07-31 |
| EP3213056A1 (en) | 2017-09-06 |
| EP3213056B1 (en) | 2020-08-12 |
| WO2016069764A1 (en) | 2016-05-06 |
| DK3213056T3 (da) | 2020-09-28 |
| CN107110785A (zh) | 2017-08-29 |
| US12158472B2 (en) | 2024-12-03 |
| JP2021119345A (ja) | 2021-08-12 |
| EP4033223A1 (en) | 2022-07-27 |
| JP2023162207A (ja) | 2023-11-08 |
| CN115753702A (zh) | 2023-03-07 |
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