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DK3502253T3 - Hidtil ukendte crispr-enzymer og -systemer - Google Patents

Hidtil ukendte crispr-enzymer og -systemer Download PDF

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Publication number
DK3502253T3
DK3502253T3 DK18188126.9T DK18188126T DK3502253T3 DK 3502253 T3 DK3502253 T3 DK 3502253T3 DK 18188126 T DK18188126 T DK 18188126T DK 3502253 T3 DK3502253 T3 DK 3502253T3
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DK
Denmark
Prior art keywords
systems
still unknown
crispr enzymes
unknown crispr
enzymes
Prior art date
Application number
DK18188126.9T
Other languages
English (en)
Inventor
Feng Zhang
Bernd Zetsche
Jonathan S Gootenberg
Omar O Abudayyeh
Ian Slaymaker
Original Assignee
Broad Inst Inc
Massachusetts Inst Technology
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55274964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3502253(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Broad Inst Inc, Massachusetts Inst Technology, Harvard College filed Critical Broad Inst Inc
Application granted granted Critical
Publication of DK3502253T3 publication Critical patent/DK3502253T3/da

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
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    • A61P27/00—Drugs for disorders of the senses
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    • A—HUMAN NECESSITIES
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/16—Aptamers
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3519—Fusion with another nucleic acid
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
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  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK18188126.9T 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer DK3502253T3 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562181739P 2015-06-18 2015-06-18
US201562193507P 2015-07-16 2015-07-16
US201562201542P 2015-08-05 2015-08-05
US201562205733P 2015-08-16 2015-08-16
US201562232067P 2015-09-24 2015-09-24
US14/975,085 US9790490B2 (en) 2015-06-18 2015-12-18 CRISPR enzymes and systems
EP16150428.7A EP3009511B2 (en) 2015-06-18 2016-01-07 Novel crispr enzymes and systems
EP16734803.6A EP3310917B2 (en) 2015-06-18 2016-06-17 Novel crispr enzymes and systems

Publications (1)

Publication Number Publication Date
DK3502253T3 true DK3502253T3 (da) 2020-08-17

Family

ID=55274964

Family Applications (5)

Application Number Title Priority Date Filing Date
DK16150428.7T DK3009511T3 (da) 2015-06-18 2016-01-07 Hidtil ukendte crispr-enzymer og systemer
DK18186003.2T DK3470519T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer
DK16734803.6T DK3310917T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer
DK19171732.1T DK3604532T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer
DK18188126.9T DK3502253T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer

Family Applications Before (4)

Application Number Title Priority Date Filing Date
DK16150428.7T DK3009511T3 (da) 2015-06-18 2016-01-07 Hidtil ukendte crispr-enzymer og systemer
DK18186003.2T DK3470519T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer
DK16734803.6T DK3310917T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer
DK19171732.1T DK3604532T3 (da) 2015-06-18 2016-06-17 Hidtil ukendte crispr-enzymer og -systemer

Country Status (16)

Country Link
US (2) US9790490B2 (da)
EP (6) EP3009511B2 (da)
JP (4) JP6898865B2 (da)
KR (2) KR20230170151A (da)
CN (6) CN114032250A (da)
AU (3) AU2016278990B2 (da)
CA (1) CA2989834A1 (da)
DK (5) DK3009511T3 (da)
ES (4) ES2646140T3 (da)
FI (2) FI3310917T4 (da)
IL (3) IL290678B2 (da)
MX (2) MX377162B (da)
RU (1) RU2737537C2 (da)
SG (1) SG10201912330QA (da)
TW (2) TWI758251B (da)
WO (1) WO2016205711A1 (da)

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MX2020011939A (es) 2021-01-29
TW201716572A (zh) 2017-05-16
DK3470519T3 (da) 2020-05-04
AU2021200010B2 (en) 2024-01-18
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RU2737537C2 (ru) 2020-12-01
US20180155716A1 (en) 2018-06-07
KR20230170151A (ko) 2023-12-18
CA2989834A1 (en) 2016-12-22
MX2017016688A (es) 2018-12-11
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AU2024202007A1 (en) 2024-04-18
DK3009511T3 (da) 2017-09-11
EP3009511A2 (en) 2016-04-20
AU2016278990B2 (en) 2020-10-22
MX377162B (es) 2025-03-07
US20160208243A1 (en) 2016-07-21
CN109207477A (zh) 2019-01-15
EP3310917B1 (en) 2020-02-12
ES2994064T3 (en) 2025-01-16
FI3604532T3 (fi) 2024-08-05
EP3009511A3 (en) 2016-06-29
IL256369A (en) 2018-02-28
DK3310917T3 (da) 2020-05-04
EP3470519B1 (en) 2020-02-12
ES2646140T3 (es) 2017-12-12
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TWI758251B (zh) 2022-03-21
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EP3604532B1 (en) 2024-05-01
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EP4403638A3 (en) 2025-03-26
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IL305044B2 (en) 2025-05-01
IL290678B1 (en) 2023-09-01
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AU2021200010A1 (en) 2021-02-11

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