DK3380468T3 - Bis-pyridazinforbindelser og anvendelse heraf i behandling af cancer - Google Patents
Bis-pyridazinforbindelser og anvendelse heraf i behandling af cancer Download PDFInfo
- Publication number
- DK3380468T3 DK3380468T3 DK16801774.7T DK16801774T DK3380468T3 DK 3380468 T3 DK3380468 T3 DK 3380468T3 DK 16801774 T DK16801774 T DK 16801774T DK 3380468 T3 DK3380468 T3 DK 3380468T3
- Authority
- DK
- Denmark
- Prior art keywords
- bis
- cancer treatment
- pyridazine compounds
- pyridazine
- compounds
- Prior art date
Links
- UXMWOEBIPQMAQT-UHFFFAOYSA-N 3-pyridazin-3-ylpyridazine Chemical class C1=CN=NC(C=2N=NC=CC=2)=C1 UXMWOEBIPQMAQT-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1520959.6A GB201520959D0 (en) | 2015-11-27 | 2015-11-27 | Bis-pyridazine compounds and their use in treating cancer |
| PCT/EP2016/078899 WO2017089587A1 (en) | 2015-11-27 | 2016-11-25 | Bis-pyridazine compounds and their use in treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3380468T3 true DK3380468T3 (da) | 2020-07-27 |
Family
ID=55177338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16801774.7T DK3380468T3 (da) | 2015-11-27 | 2016-11-25 | Bis-pyridazinforbindelser og anvendelse heraf i behandling af cancer |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US10196382B2 (da) |
| EP (1) | EP3380468B8 (da) |
| JP (1) | JP2018535226A (da) |
| KR (1) | KR20180083426A (da) |
| CN (1) | CN108349951B (da) |
| AR (1) | AR106849A1 (da) |
| AU (1) | AU2016360970B2 (da) |
| CA (1) | CA3005102A1 (da) |
| DK (1) | DK3380468T3 (da) |
| ES (1) | ES2806723T3 (da) |
| GB (1) | GB201520959D0 (da) |
| IL (1) | IL259358A (da) |
| MX (1) | MX2018006374A (da) |
| RU (1) | RU2018122012A (da) |
| SG (1) | SG11201803814SA (da) |
| TW (1) | TW201731837A (da) |
| WO (1) | WO2017089587A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106552296B (zh) | 2015-09-29 | 2020-08-14 | 上海氪励铵勤科技发展有限公司 | 纳米粒子、其制备方法与结石取出装置及应用 |
| GB201520959D0 (en) | 2015-11-27 | 2016-01-13 | Astrazeneca Ab And Cancer Res Technology Ltd | Bis-pyridazine compounds and their use in treating cancer |
| US10323028B2 (en) | 2015-11-30 | 2019-06-18 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS59705B1 (sr) | 2011-11-21 | 2020-01-31 | Calithera Biosciences Inc | Heterociklični inhibitori glutaminaze |
| US9029531B2 (en) | 2012-11-22 | 2015-05-12 | Agios Pharmaceuticals, Inc. | Compounds and their methods of use |
| EP3092235A2 (en) * | 2014-01-06 | 2016-11-16 | Rhizen Pharmaceuticals S.A. | Novel inhibitors of glutaminase |
| GB201409624D0 (en) | 2014-05-30 | 2014-07-16 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| GB201520959D0 (en) | 2015-11-27 | 2016-01-13 | Astrazeneca Ab And Cancer Res Technology Ltd | Bis-pyridazine compounds and their use in treating cancer |
| US9938265B2 (en) | 2015-11-30 | 2018-04-10 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| US10040789B2 (en) | 2015-11-30 | 2018-08-07 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
| US10323028B2 (en) | 2015-11-30 | 2019-06-18 | Astrazeneca Ab | 1,3,4-thiadiazole compounds and their use in treating cancer |
-
2015
- 2015-11-27 GB GBGB1520959.6A patent/GB201520959D0/en not_active Ceased
-
2016
- 2016-11-23 US US15/360,332 patent/US10196382B2/en not_active Expired - Fee Related
- 2016-11-25 MX MX2018006374A patent/MX2018006374A/es unknown
- 2016-11-25 KR KR1020187017944A patent/KR20180083426A/ko not_active Withdrawn
- 2016-11-25 ES ES16801774T patent/ES2806723T3/es active Active
- 2016-11-25 SG SG11201803814SA patent/SG11201803814SA/en unknown
- 2016-11-25 TW TW105138848A patent/TW201731837A/zh unknown
- 2016-11-25 AU AU2016360970A patent/AU2016360970B2/en not_active Ceased
- 2016-11-25 WO PCT/EP2016/078899 patent/WO2017089587A1/en not_active Ceased
- 2016-11-25 CN CN201680064313.0A patent/CN108349951B/zh not_active Expired - Fee Related
- 2016-11-25 DK DK16801774.7T patent/DK3380468T3/da active
- 2016-11-25 CA CA3005102A patent/CA3005102A1/en not_active Abandoned
- 2016-11-25 JP JP2018526706A patent/JP2018535226A/ja not_active Withdrawn
- 2016-11-25 EP EP16801774.7A patent/EP3380468B8/en active Active
- 2016-11-25 RU RU2018122012A patent/RU2018122012A/ru not_active Application Discontinuation
- 2016-11-29 AR ARP160103650A patent/AR106849A1/es unknown
-
2018
- 2018-05-14 IL IL259358A patent/IL259358A/en unknown
-
2019
- 2019-02-04 US US16/266,361 patent/US10577354B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN108349951A (zh) | 2018-07-31 |
| AU2016360970B2 (en) | 2019-11-07 |
| JP2018535226A (ja) | 2018-11-29 |
| SG11201803814SA (en) | 2018-06-28 |
| US20170152244A1 (en) | 2017-06-01 |
| WO2017089587A1 (en) | 2017-06-01 |
| TW201731837A (zh) | 2017-09-16 |
| AR106849A1 (es) | 2018-02-21 |
| KR20180083426A (ko) | 2018-07-20 |
| US20190169172A1 (en) | 2019-06-06 |
| EP3380468B8 (en) | 2020-11-04 |
| ES2806723T3 (es) | 2021-02-18 |
| MX2018006374A (es) | 2019-07-08 |
| IL259358A (en) | 2018-07-31 |
| GB201520959D0 (en) | 2016-01-13 |
| RU2018122012A (ru) | 2019-12-30 |
| EP3380468B1 (en) | 2020-05-20 |
| CN108349951B (zh) | 2020-11-13 |
| US10196382B2 (en) | 2019-02-05 |
| EP3380468A1 (en) | 2018-10-03 |
| CA3005102A1 (en) | 2017-06-01 |
| US10577354B2 (en) | 2020-03-03 |
| AU2016360970A1 (en) | 2018-07-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3558997T3 (da) | Aminotriazolopyridinforbindelser og deres anvendelse til behandling af cancer | |
| IL255261A0 (en) | Methods for treating cancer | |
| IL257105A (en) | Modified cells and methods of therapy | |
| DK3134125T3 (da) | Antistof-lægemiddel-konjugat og anvendelse deraf til behandling af cancer | |
| DK3733187T3 (da) | Chiral diarylmakrocyklus og anvendelse deraf i behandling af cancer | |
| DK3256218T3 (da) | Kdm1a-hæmmer og anvendelse deraf i terapi | |
| PL3303632T3 (pl) | Terapeutyczne i diagnostyczne sposoby stosowane w nowotworze | |
| DK3288581T3 (da) | Fremgangsmåde til behandling af cancer | |
| DK3015526T3 (da) | Hydrofluorolefinbaseret sammensætning og anvendelse deraf | |
| DK3227237T3 (da) | Indretning og anvendelse deraf til uv-bearbejdning af fluider | |
| ME03770B (me) | Derivati dihidroimidazopirazinona korisni za upotrebu u tretmanu raka | |
| DK2994533T3 (da) | Fremgangsmåder og sammensætninger til behandling af cancer | |
| SI3200815T1 (sl) | Postopki in sestavki za zdravljenje raka | |
| EP3474854A4 (en) | DRUG ASSOCIATIONS FOR THE TREATMENT OF CANCER | |
| DK3380086T3 (da) | Cyp26-resistente rar-alpha-selektive agonister i behandling af cancer | |
| DK3416957T3 (da) | 6-heterocyclyl-4-morpholin-4-ylpyridin-2-on-forbindelser anvendelige ved behandlingen af cancer og diabetes | |
| DK3456330T3 (da) | Cortexolon-17alpha-valerat til anvendelse ved behandling af tumorer | |
| DK3439663T3 (da) | Fremgangsmåder til behandling af pædiatriske cancere | |
| DK3374497T3 (da) | Modificerede makrofager til anvendelse i behandlingen af kræft | |
| HRP20181490T1 (hr) | Spojevi 1, 3, 4-tiadiazola i njihova upotreba u liječenju raka | |
| DK3265641T3 (da) | Stigørenhed og fremgangsmåde | |
| DK2914261T3 (da) | Syntetisk letalitet og behandling af cancer | |
| DK3321279T3 (da) | Exenatidmodificeringsmiddel og anvendelse deraf | |
| DK3576740T3 (da) | Cancerbehandling | |
| IL251903A0 (en) | Apilimod for use in the treatment of colorectal cancer |