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DK3134125T3 - Antistof-lægemiddel-konjugat og anvendelse deraf til behandling af cancer - Google Patents

Antistof-lægemiddel-konjugat og anvendelse deraf til behandling af cancer Download PDF

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Publication number
DK3134125T3
DK3134125T3 DK15720314.2T DK15720314T DK3134125T3 DK 3134125 T3 DK3134125 T3 DK 3134125T3 DK 15720314 T DK15720314 T DK 15720314T DK 3134125 T3 DK3134125 T3 DK 3134125T3
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DK
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Prior art keywords
antibody
cancer
treatment
drug conjugate
conjugate
Prior art date
Application number
DK15720314.2T
Other languages
English (en)
Inventor
Ian Rilatt
Michel Perez
Liliane Goetsch
Matthieu Broussas
Charlotte Beau-Larvor
Jean-François Haeuw
Original Assignee
Pf Medicament
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Publication of DK3134125T3 publication Critical patent/DK3134125T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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