DK3223835T3 - Intestinal microbiota and gvhd - Google Patents
Intestinal microbiota and gvhd Download PDFInfo
- Publication number
- DK3223835T3 DK3223835T3 DK15862844.6T DK15862844T DK3223835T3 DK 3223835 T3 DK3223835 T3 DK 3223835T3 DK 15862844 T DK15862844 T DK 15862844T DK 3223835 T3 DK3223835 T3 DK 3223835T3
- Authority
- DK
- Denmark
- Prior art keywords
- gvhd
- intestinal microbiota
- microbiota
- intestinal
- Prior art date
Links
- 244000005709 gut microbiome Species 0.000 title 1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Analytical Chemistry (AREA)
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- Mycology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462084219P | 2014-11-25 | 2014-11-25 | |
| US201562105063P | 2015-01-19 | 2015-01-19 | |
| US201562111949P | 2015-02-04 | 2015-02-04 | |
| PCT/US2015/062734 WO2016086161A1 (en) | 2014-11-25 | 2015-11-25 | Intestinal microbiota and gvhd |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3223835T3 true DK3223835T3 (en) | 2025-02-17 |
Family
ID=56075052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15862844.6T DK3223835T3 (en) | 2014-11-25 | 2015-11-25 | Intestinal microbiota and gvhd |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20170258854A1 (da) |
| EP (1) | EP3223835B1 (da) |
| JP (3) | JP6777643B2 (da) |
| CN (1) | CN107249609A (da) |
| AU (3) | AU2015353465B2 (da) |
| DK (1) | DK3223835T3 (da) |
| ES (1) | ES3010296T3 (da) |
| FI (1) | FI3223835T3 (da) |
| PL (1) | PL3223835T3 (da) |
| PT (1) | PT3223835T (da) |
| WO (1) | WO2016086161A1 (da) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| JP2016509003A (ja) | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| KR20170091157A (ko) | 2014-12-23 | 2017-08-08 | 4디 파마 리서치 리미티드 | 피린 폴리펩티드 및 면역 조정 |
| KR102523805B1 (ko) | 2014-12-23 | 2023-04-20 | 4디 파마 리서치 리미티드 | 면역 조정 |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| RS59038B1 (sr) | 2015-06-15 | 2019-08-30 | 4D Pharma Res Ltd | Kompozicije koje sadrže bakterijske sojeve |
| JP6426264B2 (ja) | 2015-06-15 | 2018-11-21 | フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited | 細菌株を含む組成物 |
| PL3240554T3 (pl) | 2015-06-15 | 2020-02-28 | 4D Pharma Research Limited | Blautia stercosis i wexlerae do stosowania w leczeniu chorób zapalnych i autoimmunologicznych |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| CA3005781C (en) | 2015-11-20 | 2019-01-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| HK1246670B (en) | 2016-03-04 | 2020-05-15 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| US11514289B1 (en) * | 2016-03-09 | 2022-11-29 | Freenome Holdings, Inc. | Generating machine learning models using genetic data |
| US9999641B2 (en) | 2016-06-14 | 2018-06-19 | Vedanta Biosciences, Inc. | Treatment of clostridium difficile infection |
| KR102554351B1 (ko) | 2016-06-14 | 2023-07-13 | 베단타 바이오사이언시즈, 인크. | 클로스트리디움 디피실레 감염의 치료 |
| TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| US20180185421A1 (en) * | 2016-08-29 | 2018-07-05 | Tokyo Metropolitan Government | Composition comprising fecal microbiota |
| AU2017345600A1 (en) * | 2016-10-21 | 2019-05-23 | Icahn School Of Medicine At Mount Sinai | Method of predicting graft versus host disease |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| FR3062063B1 (fr) * | 2017-01-26 | 2019-04-19 | Centre National De La Recherche Scientifique | Microbiote fecal pour traiter des patients subissant une greffe de cellules souches hematopoietiques |
| EP3388069B1 (en) | 2017-04-12 | 2019-05-01 | ETH Zurich | Consortia of living bacteria useful for treatment of microbiome dysbiosis |
| EP3630136B1 (en) | 2017-05-22 | 2021-04-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MA41708A (fr) | 2017-05-24 | 2020-04-08 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| EP3600363B1 (en) | 2017-06-14 | 2020-12-02 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| WO2018229188A1 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| HUE052258T2 (hu) | 2017-06-14 | 2021-04-28 | 4D Pharma Res Ltd | Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása |
| EP3703720A1 (en) | 2017-10-30 | 2020-09-09 | Seres Therapeutics, Inc. | Compositions and methods for treating antibiotic resistance |
| JP2021502964A (ja) | 2017-11-14 | 2021-02-04 | エヴェロ バイオサイエンシズ,インコーポレーテッド | ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法 |
| CN111741762A (zh) * | 2017-11-24 | 2020-10-02 | 防御素治疗学公司 | 使用防御素预防和治疗移植物抗宿主病 |
| FR3078627B1 (fr) * | 2018-03-09 | 2020-11-13 | Maat Pharma | Procedure de collecte de selles et procede de preparation d'un echantillon pour transplantation de microbiote fecal |
| EP3597202A1 (en) * | 2018-07-20 | 2020-01-22 | Maat Pharma | Fecal microbiota composition, for use in reducing treatment-induced inflammation |
| CN112689506A (zh) * | 2018-08-05 | 2021-04-20 | 达·沃尔泰拉公司 | 用于治疗移植物抗宿主疾病的组合物 |
| IL280779B2 (en) | 2018-08-17 | 2025-05-01 | Vedanta Biosciences Inc | Compositions for use in the treatment or prevention of Clostridium difficile infection |
| WO2020079021A1 (en) | 2018-10-15 | 2020-04-23 | Pharmabiome Ag | Consortia of living bacteria useful for treatment of cancer related diseases, particularly graft versus host disease |
| US20220054560A1 (en) * | 2018-10-15 | 2022-02-24 | Pharmabiome Ag | Consortia of living bacteria useful for treatment of colorectal cancer |
| EP3866822A1 (en) * | 2018-10-19 | 2021-08-25 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| US20220023419A1 (en) * | 2018-11-28 | 2022-01-27 | The Council Of The Queensland Institute Of Medical Research | Inhibiting inflammation |
| GB201900744D0 (en) * | 2019-01-18 | 2019-03-06 | Mars Inc | Monitoring tools and diagnostic methods |
| US20220218800A1 (en) * | 2019-05-06 | 2022-07-14 | Synthetic Biologics, Inc. | Beta-lactamase compositions for treatment of graft versus host disease |
| KR102401535B1 (ko) * | 2019-07-30 | 2022-05-24 | 주식회사 고바이오랩 | 간 손상 예방, 개선, 또는 치료용 조성물 |
| JP7303372B2 (ja) | 2019-07-30 | 2023-07-04 | コバイオラブス,インコーポレーテッド | 肝損傷予防、改善、または治療用組成物、および肝損傷予防、改善、または治療方法 |
| CN112538439B (zh) * | 2019-09-04 | 2022-03-15 | 欧斐生 | 一种植物乳杆菌及其制备植物性凝态酸奶、改善肠道菌相的用途 |
| EP4048081A2 (en) * | 2019-10-21 | 2022-08-31 | DuPont Nutrition Biosciences ApS | Compositions for gut health |
| US20230024068A1 (en) * | 2019-11-26 | 2023-01-26 | Jsr Corporation | Prophylactic or therapeutic composition for graft-versus-host disease |
| CN111549108B (zh) * | 2020-05-28 | 2023-08-04 | 浙江省农业科学院 | 一种不同剩余采食量对蛋鸭肠道微生物组成、功能差异分析方法 |
| WO2022092915A1 (ko) * | 2020-10-30 | 2022-05-05 | 가톨릭대학교 산학협력단 | Gdf15를 유효성분으로 함유하는 면역질환의 예방 및 치료용 조성물 |
| KR102269966B1 (ko) * | 2021-01-12 | 2021-06-28 | 주식회사 바이오뱅크힐링 | 루미노코쿠스 파에시스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도 |
| WO2022204357A1 (en) * | 2021-03-24 | 2022-09-29 | Board Of Regents, The University Of Texas System | Methods and compositions for treating cancer therapy-induced neutropenic fever and/or gvhd |
| US20240226191A1 (en) * | 2021-05-10 | 2024-07-11 | Microba Ip Pty Ltd | Compositions and methods for treating disease |
| CN113493849A (zh) * | 2021-09-09 | 2021-10-12 | 北京泱深生物信息技术有限公司 | 一种可用于诊断生长发育迟缓的产品 |
| US20250295712A1 (en) * | 2022-02-09 | 2025-09-25 | The Regents Of The University Of Michigan | Compositions and methods for modulating gut microbiomes |
| KR20240114298A (ko) | 2023-01-12 | 2024-07-23 | 에스엔제이 파마 인크 | 감염 저항성 장내 균주 및 그 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1013829A2 (pt) * | 2009-04-20 | 2019-09-24 | Qteros Inc | composições e métodos para fermentação de biomassa |
| US20140348811A1 (en) * | 2011-07-27 | 2014-11-27 | Max International, Llc | Compositions comprising sugar-cysteine products |
| US20130115232A1 (en) * | 2011-10-03 | 2013-05-09 | Fred Hutchinson Cancer Research Center | Methods for detecting graft-versus-host disease |
| CN104160014A (zh) | 2011-12-01 | 2014-11-19 | 国立大学法人东京大学 | 诱导调节性t细胞的增殖或积累的人源细菌 |
| WO2013121573A1 (ja) * | 2012-02-17 | 2013-08-22 | 住友商事株式会社 | ソフトバイオマスの分解方法 |
| WO2013177596A2 (en) * | 2012-05-25 | 2013-11-28 | Sloan Kettering Institute For Cancer | Methods for treating gi syndrome and graft versus host disease |
| US20140112985A1 (en) | 2012-10-22 | 2014-04-24 | Polonez Therapeutics Llc | Method of prevention and treatment of clostridium difficile infection |
| US8906668B2 (en) * | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| JP2016509003A (ja) * | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| WO2014153194A2 (en) * | 2013-03-14 | 2014-09-25 | Seres Health, Inc. | Methods for pathogen detection and enrichment from materials and compositions |
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2015
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- 2015-11-25 JP JP2017545883A patent/JP6777643B2/ja active Active
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- 2015-11-25 PT PT158628446T patent/PT3223835T/pt unknown
- 2015-11-25 FI FIEP15862844.6T patent/FI3223835T3/fi active
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2020
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| US20170258854A1 (en) | 2017-09-14 |
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| CA2968325A1 (en) | 2016-06-02 |
| JP2017537979A (ja) | 2017-12-21 |
| AU2021258070A1 (en) | 2021-11-25 |
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| WO2016086161A1 (en) | 2016-06-02 |
| PT3223835T (pt) | 2025-02-14 |
| EP3223835A4 (en) | 2018-10-24 |
| JP6777643B2 (ja) | 2020-10-28 |
| FI3223835T3 (fi) | 2025-06-16 |
| CN107249609A (zh) | 2017-10-13 |
| ES3010296T3 (en) | 2025-04-02 |
| PL3223835T3 (pl) | 2025-03-31 |
| AU2015353465A1 (en) | 2017-05-25 |
| JP2023101670A (ja) | 2023-07-21 |
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