[go: up one dir, main page]

DK2846809T3 - Behandling af myelosuppression - Google Patents

Behandling af myelosuppression Download PDF

Info

Publication number
DK2846809T3
DK2846809T3 DK13787651.2T DK13787651T DK2846809T3 DK 2846809 T3 DK2846809 T3 DK 2846809T3 DK 13787651 T DK13787651 T DK 13787651T DK 2846809 T3 DK2846809 T3 DK 2846809T3
Authority
DK
Denmark
Prior art keywords
myelosuppression
treatment
Prior art date
Application number
DK13787651.2T
Other languages
English (en)
Inventor
Stephen Marcus
Original Assignee
Cantex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantex Pharmaceuticals Inc filed Critical Cantex Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2846809T3 publication Critical patent/DK2846809T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK13787651.2T 2012-05-09 2013-03-13 Behandling af myelosuppression DK2846809T3 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201261644556P 2012-05-09 2012-05-09
US201261644623P 2012-05-09 2012-05-09
US201261648043P 2012-05-16 2012-05-16
US201261653362P 2012-05-30 2012-05-30
US201261664611P 2012-06-26 2012-06-26
US201261668709P 2012-07-06 2012-07-06
US201261678053P 2012-07-31 2012-07-31
US201261702207P 2012-09-17 2012-09-17
US201261724836P 2012-11-09 2012-11-09
PCT/US2013/031053 WO2013169355A1 (en) 2012-05-09 2013-03-13 Treatment of myelosuppression

Publications (1)

Publication Number Publication Date
DK2846809T3 true DK2846809T3 (da) 2021-01-18

Family

ID=49549076

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13787651.2T DK2846809T3 (da) 2012-05-09 2013-03-13 Behandling af myelosuppression

Country Status (20)

Country Link
US (6) US9271999B2 (da)
EP (2) EP2846809B1 (da)
JP (3) JP6177885B2 (da)
KR (2) KR102452803B1 (da)
CN (3) CN113521093A (da)
AU (1) AU2013260101B2 (da)
BR (1) BR112014028094B1 (da)
CA (2) CA2872855C (da)
CL (2) CL2014003017A1 (da)
DK (1) DK2846809T3 (da)
EA (1) EA029382B1 (da)
ES (1) ES2848050T3 (da)
HU (1) HUE053247T2 (da)
IL (1) IL235593B (da)
LT (1) LT2846809T (da)
MX (2) MX370567B (da)
PL (1) PL2846809T3 (da)
PT (1) PT2846809T (da)
SG (3) SG10201603059YA (da)
WO (1) WO2013169355A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX370567B (es) 2012-05-09 2019-12-17 Cantex Pharmaceuticals Inc Tratamiento de mielosupresion.
CN105848672A (zh) * 2013-10-22 2016-08-10 坎泰克斯制药股份有限公司 治疗和预防辐射损伤的方法
WO2015142924A1 (en) 2014-03-17 2015-09-24 Cantex Pharmaceuticals, Inc. Multivalent cation formulations of partially desulfated heparins
EP3258941A4 (en) 2015-02-17 2018-09-26 Cantex Pharmaceuticals, Inc. Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
MX383691B (es) 2015-03-06 2025-03-14 Beyondspring Pharmaceuticals Inc Método de tratamiento de cáncer asociado con una mutación de ras.
ES2910035T3 (es) 2015-07-13 2022-05-11 Beyondspring Pharmaceuticals Inc Composiciones de plinabulina
IL260933B2 (en) 2016-02-08 2023-04-01 Beyondspring Pharmaceuticals Inc Preparations containing tocorsol or its analogues
KR20190015361A (ko) 2016-06-06 2019-02-13 비욘드스프링 파마수티컬스, 인코포레이티드. 호중구감소증을 줄이는 조성물 및 방법
JP2020503363A (ja) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド チューブリン結合化合物およびその治療的使用
WO2018144764A1 (en) 2017-02-01 2018-08-09 Beyondspring Pharmaceuticals, Inc. Method of reducing neutropenia
CN107569486A (zh) * 2017-08-23 2018-01-12 北京京佑奇康生物科技有限公司 孟鲁司特钠治疗血小板减少症的新用途
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
EP3743074A4 (en) * 2018-01-24 2021-12-15 Beyondspring Pharmaceuticals Inc. COMPOSITION AND METHOD FOR REDUCING THROMBOCYTOPENIA BY THE ADMINISTRATION OF PLINABULINE
WO2019195658A1 (en) 2018-04-05 2019-10-10 Dana-Farber Cancer Institute, Inc. Sting levels as a biomarker for cancer immunotherapy
US20200237872A1 (en) * 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
CN113993522A (zh) 2019-04-17 2022-01-28 指南针探路者有限公司 用赛洛西宾治疗焦虑障碍、头痛病症和进食障碍的方法
WO2021041532A1 (en) * 2019-08-26 2021-03-04 Dana-Farber Cancer Institute, Inc. Use of heparin to promote type 1 interferon signaling
CA3157404A1 (en) * 2019-11-13 2021-05-20 Taiho Pharmaceutical Co., Ltd. Novel salt of terphenyl compound
WO2021207697A1 (en) 2020-04-10 2021-10-14 Cantex Pharmaceuticals, Inc. Treatment of acute lung injury
EP4182452A4 (en) 2020-07-14 2024-07-31 Optimvia, LLC METHOD FOR THE SYNTHESIS OF NON-ANTICOAGULATING HEPARAN SULFATE
CA3215047A1 (en) 2021-04-09 2022-10-13 Lan Huang Therapeutic compositions and methods for treating tumors
KR102856472B1 (ko) 2021-10-21 2025-09-11 숙명여자대학교산학협력단 혈액암 치료를 위한 글리세오플빈 병용요법
CN116212020B (zh) * 2022-12-09 2025-05-30 中国医学科学院放射医学研究所 Jak抑制剂防治辐射诱导骨髓抑制和肠道损伤药物中的应用
CN116983325A (zh) * 2023-08-18 2023-11-03 首都儿科研究所 共同活性成分在制备用于治疗肿瘤的药物中的应用

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374910A1 (fr) 1976-10-23 1978-07-21 Choay Sa Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations
US5804374A (en) 1980-12-05 1998-09-08 Massachusetts Insti. Technology Nuclear factors associates with transcriptional regulation
FR2553287B1 (fr) 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
DE3422518A1 (de) 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
FR2584606A1 (fr) 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
US5380716A (en) 1988-12-15 1995-01-10 Glycomed, Inc. Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
IT1234826B (it) 1989-01-30 1992-05-29 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
US5399493A (en) 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
WO1991015216A1 (en) 1990-04-05 1991-10-17 Kennedy Thomas P Method and medicament for prevention or medication of human leucocyte elastase-mediated pulmonary diseases
US5250519A (en) 1991-03-29 1993-10-05 Glycomed Incorporated Non-anticoagulant heparin derivatives
IT1254216B (it) 1992-02-25 1995-09-14 Opocrin Spa Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
WO1993019734A1 (en) 1992-04-02 1993-10-14 Baker Norton Pharmaceuticals, Inc. Method and composition for treating antigen-induced and exercise-induced asthma
US5668118A (en) 1992-07-24 1997-09-16 Cavalier Pharmaceuticals Method of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G
US5306724A (en) 1992-08-17 1994-04-26 Clintec Nutrition Company Method for preventing and treating atherosclerosis
GB2270841A (en) 1992-09-09 1994-03-30 Merck & Co Inc Compositions for Treating vascular restenosis
US5696100A (en) 1992-12-22 1997-12-09 Glycomed Incorporated Method for controlling O-desulfation of heparin and compositions produced thereby
US5296471A (en) 1992-12-22 1994-03-22 Glycomed Incorporated Method for controlling o-desulfation of heparin and compositions produced thereby
WO1994018989A1 (en) 1993-02-22 1994-09-01 Cavalier Pharmaceuticals, Inc. Use of heparin to inhibit interleukin-8
SE9302135D0 (sv) 1993-06-18 1993-06-18 Kabi Pharmacia Ab New pharmaceutical composition
US5840707A (en) 1993-10-04 1998-11-24 Albany Medical College Stabilizing and delivery means of biological molecules
US5994318A (en) 1993-10-04 1999-11-30 Albany Medical College Cochleate delivery vehicles
JPH09512822A (ja) 1994-05-06 1997-12-22 グリコメド・インコーポレイテッド O−脱硫酸化ヘパリン誘導体とその製造法および使用
US5804560A (en) 1995-01-06 1998-09-08 Sibia Neurosciences, Inc. Peptide and peptide analog protease inhibitors
EP0918461B1 (en) 1996-07-29 2004-10-27 Paringenix, Inc. Methods of treating asthma with o-desulfated heparin
US6154502A (en) 1996-08-22 2000-11-28 Intel Corporation Signal constellation slicer
US7258857B2 (en) 1996-11-22 2007-08-21 The Trustees Of Columbia University In The City Of New York Rage-related methods for treating inflammation
ATE240113T1 (de) 1997-02-15 2003-05-15 Millennium Pharm Inc Behandlung von infarkten durch inhibierung von nf-kappab
DE69821932T2 (de) 1997-05-30 2004-12-16 Arch Development Corp., Chicago P-selectin translokation ins vaskulare epitheliale lumen durch ionisierende strahlung
US6406862B1 (en) 1998-10-06 2002-06-18 The United States Of America As Represented By The Secretary Of The Army Dip-stick assay for C-reactive protein
IL142255A0 (en) 1998-11-13 2002-03-10 Lilly Co Eli Method of treating heparin-induced thrombocytopenia
US20030083231A1 (en) 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US6153217A (en) 1999-01-22 2000-11-28 Biodelivery Sciences, Inc. Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents
US6514502B1 (en) 1999-01-26 2003-02-04 Schering-Plough Veterinary Corporation Propagation of bovine cononavirus in chinese hamster ovary cells
AU763042B2 (en) 1999-09-13 2003-07-10 Charlotte-Mecklenburg Hospital Authority Method of inhibiting NF-kappaB with heparin
US7781416B2 (en) 2000-01-25 2010-08-24 Sigma-Tau Research Switzerland S.A. Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
US6489311B1 (en) 2000-05-02 2002-12-03 Charlotte-Mecklenburg Hospital Authoirty Method for the prevention of apoptosis
CZ305273B6 (cs) * 2001-04-18 2015-07-15 Prometic Biosciences Inc. Mastné kyseliny jako faktory aktivace a přežití neutrofilů
AU2003230985A1 (en) 2002-04-18 2003-11-03 Stephen H. Embury Method and composition for preventing pain in sickle cell patients
AU2003251829B2 (en) 2002-07-09 2009-12-10 Radical Therapeutix Method to inhibit ischemia and reperfusion injury
US8404716B2 (en) 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
AU2003293122A1 (en) 2002-11-27 2004-06-23 Massachusetts Institute Of Technology Methods for synthesizing polysaccharides
US20040180812A1 (en) * 2002-12-13 2004-09-16 Technology Center Methods of treating and preventing proliferative disease
CA2522275A1 (en) 2003-05-20 2005-01-06 Transtech Pharma, Inc. Rage antagonists as agents to reverse amyloidosis and diseases associated therewith
WO2005089365A2 (en) 2004-03-16 2005-09-29 The General Hospital Corporation Treatment and prevention of abnormal cellular proliferation
US8022279B2 (en) * 2004-04-22 2011-09-20 Celator Pharmaceuticals, Inc. Liposomal formulations of anthracycline agents and cytidine analogs
US20050261241A1 (en) 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
US20050282775A1 (en) 2004-06-16 2005-12-22 Paringenix, Inc. Method and medicament for sulfated polysaccharide treatment of inflammation without inducing platelet activation and heparin-induced thrombocytopenia syndrome
US7468358B2 (en) 2004-06-16 2008-12-23 Paringenix, Inc. Method and medicament for sulfated polysaccharide treatment of heparin-induced thrombocytopenia (HIT) syndrome
US20060040896A1 (en) 2004-08-18 2006-02-23 Paringenix, Inc. Method and medicament for anticoagulation using a sulfated polysaccharide with enhanced anti-inflammatory activity
JP2006076968A (ja) 2004-09-10 2006-03-23 Seikagaku Kogyo Co Ltd 生理活性分子含有架橋ヘパリンゲル組成物
US20070021378A1 (en) 2005-07-22 2007-01-25 The Regents Of The University Of California Heparin compositions and selectin inhibition
WO2007019554A2 (en) 2005-08-08 2007-02-15 Momenta Pharmaceuticals, Inc. Polysaccharides for delivery of active agents
CN101400785B (zh) 2005-09-30 2013-09-25 宝生物工程株式会社 T细胞群的制备方法
BRPI0619999A2 (pt) 2005-12-16 2011-10-25 Dnp Canada Inc derivados de quitina para hiperlipidemia
WO2007115372A1 (en) 2006-04-10 2007-10-18 Monash University A method of modulating beta-amyloid peptide production
ES2553332T3 (es) 2006-07-26 2015-12-07 Intrexon Corporation Métodos y composiciones para el tratamiento de enfermedades
WO2008085562A2 (en) 2006-09-20 2008-07-17 The Johns Hopkins University Combinatorieal therapy of cancer and infectious diseases with anti-b7-h1 antibodies
WO2008106584A1 (en) 2007-02-28 2008-09-04 Paringenix, Inc. O-desulfated heparins treating acute exacerbations of chronic obstructive pulmonary disease
CA2689914C (en) * 2007-06-01 2016-08-16 Abraxis Bioscience, Llc Use of protein-bound taxane nanoparticles in the treatment of recurrent gynecological cancers
WO2009015183A1 (en) 2007-07-23 2009-01-29 University Of Utah Research Foundation Method for blocking ligation of the receptor for advanced glycation end-products (rage)
US8569262B2 (en) 2007-11-02 2013-10-29 Momenta Pharmaceuticals, Inc. Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
WO2009117677A2 (en) 2008-03-21 2009-09-24 University Of Utah Research Foundation Methods for controlling intracellular calcium levels associated with an ischemic event
AU2009231634B2 (en) 2008-04-04 2014-05-15 University Of Utah Research Foundation Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
US8476249B2 (en) * 2009-05-07 2013-07-02 Glaxosmithkline Llc Method of treating thrombocytopenia
EP2482903B1 (en) 2009-09-29 2018-11-14 Vectura GmbH Improved method for treatment of patients with cystic fibrosis
US20130143840A1 (en) 2010-03-12 2013-06-06 Christopher Richard Parish Heparan sulfate replacement therapy
CA2793647C (en) * 2010-03-24 2020-09-01 Biorealites Prophylaxis of colorectal and gastrointestinal cancer
EP3153173A1 (en) 2010-06-28 2017-04-12 Stemtech International, Inc. Methods and compositions for enhancing stem cell mobilization
EP2670396A1 (en) * 2011-01-31 2013-12-11 Celgene Corporation Pharmaceutical compositions of cytidine analogs and methods of use thereof
WO2012106379A1 (en) * 2011-02-01 2012-08-09 Paringenix, Inc. Sensitization of cancer cells to treatment
WO2013016181A1 (en) 2011-07-22 2013-01-31 Paringenix, Inc. Compositions and methods for anti-coagulation
BR112014027333A2 (pt) 2012-05-01 2017-07-18 Univ Duke composição, métodos de tratamento ou melhora, de prevenção, e, de diagnóstico de uma condição prejudicial que está associada com o teor elevado de sulfato de heparano em um indivíduo que foi o receptor de um órgão, tecido ou células transplantados
MX370567B (es) 2012-05-09 2019-12-17 Cantex Pharmaceuticals Inc Tratamiento de mielosupresion.
CN113616779A (zh) 2013-02-28 2021-11-09 哈佛学院校长同事会 用于动员干细胞的方法和组合物
CN105848672A (zh) 2013-10-22 2016-08-10 坎泰克斯制药股份有限公司 治疗和预防辐射损伤的方法
US20160296552A1 (en) 2013-10-24 2016-10-13 Cantex Pharmaceuticals, Inc. Treating Bacterial Infections of the Lung
WO2015142924A1 (en) 2014-03-17 2015-09-24 Cantex Pharmaceuticals, Inc. Multivalent cation formulations of partially desulfated heparins
EP3258941A4 (en) * 2015-02-17 2018-09-26 Cantex Pharmaceuticals, Inc. Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
WO2016133907A1 (en) 2015-02-17 2016-08-25 Cantex Pharmaceuticals, Inc. Adoptive cell transfer methods
US20170106011A1 (en) 2015-10-20 2017-04-20 Cantex Pharmaceuticals, Inc. Methods of treating traumatic brain injury and sequelae
WO2017123549A1 (en) 2016-01-11 2017-07-20 Cantex Pharmaceuticals, Inc. Methods of treating or preventing graft-versus-host disease using hmgb1-interacting heparinoids

Also Published As

Publication number Publication date
US20130323230A1 (en) 2013-12-05
MX2019009437A (es) 2019-10-02
KR20150023361A (ko) 2015-03-05
SG11201407340YA (en) 2014-12-30
IL235593B (en) 2019-06-30
CN108498532B (zh) 2021-07-23
MX2014013633A (es) 2015-07-06
SG10201914117QA (en) 2020-02-27
CN113521093A (zh) 2021-10-22
JP2017105850A (ja) 2017-06-15
KR20200118510A (ko) 2020-10-15
JP2019026647A (ja) 2019-02-21
US20220354882A1 (en) 2022-11-10
US9271999B2 (en) 2016-03-01
PT2846809T (pt) 2021-02-05
US20130303481A1 (en) 2013-11-14
KR102165348B1 (ko) 2020-10-14
AU2013260101A1 (en) 2014-12-18
EP3785720A1 (en) 2021-03-03
JP6448694B2 (ja) 2019-01-09
CA2872855A1 (en) 2013-11-14
EP2846809A4 (en) 2015-12-30
SG10201603059YA (en) 2016-05-30
BR112014028094B1 (pt) 2022-03-03
CN108498532A (zh) 2018-09-07
CA2872855C (en) 2021-07-27
AU2013260101B2 (en) 2016-10-27
JP6726252B2 (ja) 2020-07-22
CL2014003017A1 (es) 2015-07-10
LT2846809T (lt) 2021-01-25
US20180296590A1 (en) 2018-10-18
HK1207574A1 (en) 2016-02-05
US20200038431A1 (en) 2020-02-06
IL235593A0 (en) 2015-01-29
CL2021000008A1 (es) 2021-06-11
JP6177885B2 (ja) 2017-08-09
JP2015521176A (ja) 2015-07-27
CA3122808A1 (en) 2013-11-14
EP2846809B1 (en) 2020-10-14
CN104411316A (zh) 2015-03-11
US20160213706A1 (en) 2016-07-28
ES2848050T3 (es) 2021-08-05
BR112014028094A2 (pt) 2020-06-30
US11229664B2 (en) 2022-01-25
US8734804B2 (en) 2014-05-27
KR102452803B1 (ko) 2022-10-07
PL2846809T3 (pl) 2021-07-26
EP2846809A1 (en) 2015-03-18
HUE053247T2 (hu) 2021-06-28
CN104411316B (zh) 2018-05-01
EA029382B1 (ru) 2018-03-30
MX370567B (es) 2019-12-17
WO2013169355A1 (en) 2013-11-14
MX384023B (es) 2025-03-14
EA201492052A1 (ru) 2015-08-31

Similar Documents

Publication Publication Date Title
DK2846809T3 (da) Behandling af myelosuppression
LT2885010T (lt) Tautopatijos gydymo būdai
DK2968208T3 (da) Behandling af kataplexi
DK2717941T3 (da) Behandling af cancer
DK2785349T4 (da) Kombinationsbehandling af cancer
EP3818947C0 (en) Fenestrated implant
EP2921192A4 (en) CATHETER
EP2823767A4 (en) CATHETER
DK2981255T3 (da) Terapeutiske anvendelser af empagliflozin
AR092198A1 (es) Derivados de pirazolopirimidinas
DK3626270T3 (da) Behandling af kardiovaskulære sygdomme
BR112014013850A2 (pt) conjunto de prateleiras
DK2668967T3 (da) Implantat
EP2926857A4 (en) Catheter
DK2906580T3 (da) Behandling af amyotrofisk lateral sklerose
DK2894998T3 (da) Rotation af kegle
EP2858975A4 (en) FBXO3 INHIBITORS
FR2995524B1 (fr) Prothese endo-urinaire
DK2888228T3 (da) Inhibitorer af CD40-TRAF6 interaktion
DK2838850T3 (da) Oprensning af titantetrachlorid
DK3590960T3 (da) Igg-stimuleret remyelinisering af perifere nerver
DK2916922T3 (da) Behandling af alkalisk bauxitrest
DK2825636T3 (da) Behandling af sædceller
EP2810680A4 (en) CATHETER
SMT201700011B (it) Stent