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DK2676118T3 - Fremgangsmåde til fiksering af vævsprøve - Google Patents

Fremgangsmåde til fiksering af vævsprøve Download PDF

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Publication number
DK2676118T3
DK2676118T3 DK12706226.3T DK12706226T DK2676118T3 DK 2676118 T3 DK2676118 T3 DK 2676118T3 DK 12706226 T DK12706226 T DK 12706226T DK 2676118 T3 DK2676118 T3 DK 2676118T3
Authority
DK
Denmark
Prior art keywords
tissue specimen
fixing tissue
fixing
specimen
tissue
Prior art date
Application number
DK12706226.3T
Other languages
English (en)
Inventor
Michael Otter
David Chafin
Esteban Roberts
Theiss Abbey Pierson
Original Assignee
Ventana Med Syst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Med Syst Inc filed Critical Ventana Med Syst Inc
Application granted granted Critical
Publication of DK2676118T3 publication Critical patent/DK2676118T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
DK12706226.3T 2011-02-17 2012-02-17 Fremgangsmåde til fiksering af vævsprøve DK2676118T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161463551P 2011-02-17 2011-02-17
US201161464479P 2011-03-04 2011-03-04
PCT/EP2012/052800 WO2012110646A1 (en) 2011-02-17 2012-02-17 Method for tissue sample fixation

Publications (1)

Publication Number Publication Date
DK2676118T3 true DK2676118T3 (da) 2020-05-18

Family

ID=45771797

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12706226.3T DK2676118T3 (da) 2011-02-17 2012-02-17 Fremgangsmåde til fiksering af vævsprøve

Country Status (9)

Country Link
US (3) US10126216B2 (da)
EP (1) EP2676118B1 (da)
JP (1) JP5662593B2 (da)
CN (1) CN103518127B (da)
AU (1) AU2012216987B2 (da)
CA (1) CA2822532C (da)
DK (1) DK2676118T3 (da)
ES (1) ES2791725T3 (da)
WO (1) WO2012110646A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10539487B2 (en) * 2010-03-04 2020-01-21 Ventana Medical Systems, Inc. Systems and methods for monitoring tissue sample processing
CA2788664C (en) 2010-03-04 2023-04-11 Ventana Medical Systems, Inc. Processing system for processing specimens using acoustic energy
US10126216B2 (en) * 2011-02-17 2018-11-13 Ventana Medical Systems, Inc. Method for tissue sample fixation
JP2014209090A (ja) * 2013-03-29 2014-11-06 シスメックス株式会社 細胞分析方法及び装置
DE102013223384B4 (de) * 2013-11-15 2015-05-28 Leica Biosystems Nussloch Gmbh Fixierung von Gewebeproben unter Verwendung Aldehyde freisetzender stickstoffhaltiger Verbindungen
WO2015124738A1 (en) 2014-02-24 2015-08-27 Ventana Medical Systems, Inc. Automated rna detection using labeled 2'-o-methyl rna oligonucleotide probes and signal amplification systems
WO2016041890A2 (en) * 2014-09-17 2016-03-24 Ventana Medical Systems, Inc. Compositions, methods, and systems for tissue fixation
EP3227830B8 (en) 2014-12-03 2020-07-01 Ventana Medical Systems, Inc. Methods, systems, and apparatuses for quantitative analysis of heterogeneous biomarker distribution
AU2015367416B2 (en) * 2014-12-17 2019-05-30 Ventana Medical Systems, Inc. Accurately calculating acoustic time-of-flight
EP3234581B1 (en) 2014-12-17 2020-09-23 Ventana Medical Systems, Inc. Obtaining a diffusivity constant
EP3234583B1 (en) * 2014-12-17 2020-08-19 Ventana Medical Systems, Inc. Diffusion monitoring protocol for optimized tissue fixation
JP6853177B2 (ja) * 2015-01-26 2021-03-31 ベンタナ メディカル システムズ, インコーポレイテッド 組織試料を移送するためのトランスポータシステム、組立体、および関連する方法
EP3250902B1 (en) * 2015-01-27 2024-05-08 Ventana Medical Systems, Inc. Methods for tissue sample fixation using an extended soak in aldehyde-based fixative solutions
EP3256844B1 (en) * 2015-02-09 2021-04-14 Ventana Medical Systems, Inc. System and method for standardizing diffusion of a fluid into tissues
US10788403B2 (en) * 2015-03-11 2020-09-29 Tissuevision, Inc. Systems and methods for serial staining and imaging
CN106501057A (zh) * 2016-03-29 2017-03-15 吴菡 一种细胞标本石蜡包埋的改良技术
CN105891208B (zh) * 2016-04-13 2019-03-26 华中科技大学 用于构建标准图谱数据集的细胞构筑信息获取方法
EP3559628B1 (en) * 2016-12-22 2021-08-18 Ventana Medical Systems, Inc. System and method for sample processing
CN110926907A (zh) * 2019-10-28 2020-03-27 内蒙古农业大学 一种适用于制作马属动物卵巢石蜡切片的方法
US20230151415A1 (en) * 2020-04-07 2023-05-18 Advanced Cell Diagnostics, Inc. Methods for detecting target nucleic acids by in situ hybridization and a kit thereof
CN117651521A (zh) 2021-05-13 2024-03-05 文塔纳医疗系统公司 对组织固定时间的实时预测

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2017A (en) * 1841-03-26 The graphic co
US3961097A (en) 1971-10-28 1976-06-01 Gravlee Jr Joseph F Method of preparing tissue for microscopic examination
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4318980A (en) 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
AU550225B2 (en) 1982-05-26 1986-03-06 Ontario Cancer Institute, The Ultrasonic imaging device
US4839194A (en) 1985-07-05 1989-06-13 Bone Diagnostic Center Methods of preparing tissue samples
US4656047A (en) 1986-03-06 1987-04-07 Kok Lanbrecht P Rapid method for cell block preparation
GB2192712B (en) 1986-06-10 1990-02-14 Lab Supplies And Instr Fixative
GB8803109D0 (en) 1988-02-11 1988-03-09 Deltanine Research Ltd Improvements in/relating to clinical testing monitoring & pharmaceutical compositions for treatment of auto-immune diseases
US5665141A (en) 1988-03-30 1997-09-09 Arjo Hospital Equipment Ab Ultrasonic treatment process
US5343863A (en) 1988-05-11 1994-09-06 Lunar Corporation Ultrasonic densitometer device and method
US4891239A (en) 1988-07-05 1990-01-02 Raytheon Company Method and apparatus for ultrafast microwave tissue fixation
US5197475A (en) 1988-08-10 1993-03-30 The Board Of Regents, The University Of Texas System Method and apparatus for analyzing material properties using ultrasound
US5089288A (en) 1989-06-24 1992-02-18 Berger Hermann J Method for impregnating tissue samples in paraffin
WO1991003718A1 (en) 1989-09-01 1991-03-21 Digene Diagnostics, Inc. A highly sensitive method for detecting peroxidase
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
EP0574391B1 (en) 1990-10-18 2002-06-26 Cancerforskningsfonden af 1989 (fonden til fremme af eksperimentel cancerforskning) Antibodies against the urokinase receptor and their use
US5639423A (en) 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
WO1994007138A1 (en) 1992-09-14 1994-03-31 Fodstad Oystein Detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations
AU2895192A (en) 1992-10-23 1994-05-24 Regents Of The University Of California, The Substances having the growth-promoting effect of amyloid precursor protein
JPH08505855A (ja) 1993-01-12 1996-06-25 ザ ロックフェラー ユニヴァーシティ 炎症を促進する細胞の経内皮移動を調節する方法および関連するその測定方法
DE4313216C2 (de) 1993-04-22 1995-12-14 Max Planck Gesellschaft Ultraschallmeßgerät mit mindestens einem nicht-piezoelektrischen Resonatorkammerkörper und außen angeordneten elektro-akustischen Wandlern
GB9317423D0 (en) 1993-08-21 1993-10-06 Imp Cancer Res Tech Monoclonal antibodies
US5523204A (en) 1993-12-10 1996-06-04 Becton Dickinson And Company Detection of nucleic acids in cells by strand displacement amplification
US5648222A (en) 1994-07-27 1997-07-15 The Trustees Of Columbia University In The City Of New York Method for preserving cells, and uses of said method
US5931969A (en) * 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
EP0734742B1 (en) 1995-03-31 2005-05-11 Kabushiki Kaisha Toshiba Ultrasound therapeutic apparatus
WO1996040506A1 (en) 1995-06-07 1996-12-19 Jacques Michael Casparian Method of optimizing tissue for histopathologic examination
US5759864A (en) 1995-06-23 1998-06-02 Cedars Sinai Medical Center Methods for reducing background binding in antibody preparations
EP0910578A2 (en) 1996-01-19 1999-04-28 The Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
AU2429397A (en) 1996-03-29 1997-10-22 David S. Terman Polymerized staphylococcal protein a for treatment of diseases
NO301792B1 (no) 1996-07-01 1997-12-08 Norske Stats Oljeselskap Fremgangsmåte og anlegg for flytendegjöring/kondisjonering av en komprimert gass/hydrokarbonström utvunnet fra en petroleumforekomst
EP0822403B1 (en) 1996-08-02 1998-07-29 Milestone S.r.l. Process for processing organic specimens
CA2275867A1 (en) 1996-11-12 1998-05-22 Tamarkin Pharmaceutical Innovation Ltd. Method for treatment of dermatological disorders
US6793890B2 (en) 1997-08-20 2004-09-21 The University Of Miami Rapid tissue processor
ATE407353T1 (de) 1997-08-20 2008-09-15 Univ Miami Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben
ATE489613T1 (de) 1998-02-27 2010-12-15 Ventana Med Syst Inc Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
WO1999053994A1 (en) 1998-04-20 1999-10-28 Medtronic, Inc. Medical leads with enhanced biocompatibility and biostability
US6576420B1 (en) 1998-06-23 2003-06-10 Regents Of The University Of California Method for early diagnosis of, and determination of prognosis in, cancer
EP1089751A4 (en) 1998-06-23 2001-07-25 Univ Leland Stanford Junior Adjuvant therapy
CA2335747A1 (en) 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
WO2000023799A1 (en) 1998-10-21 2000-04-27 Steven Jay Smith Protein quantitation with cell imaging densitometry
US6291180B1 (en) 1999-09-29 2001-09-18 American Registry Of Pathology Ultrasound-mediated high-speed biological reaction and tissue processing
US6875583B2 (en) 2001-05-22 2005-04-05 Ted Pella, Inc. Rapid microwave-assisted fixation of fresh tissue
DE10146323B4 (de) 2001-09-20 2005-07-28 Institut Für Verbundwerkstoffe Gmbh Verfahren zur rechnergesteuerten Bestimmung von Verlaufsdaten einer Fließfront und Vorrichtung dazu
US7204959B2 (en) 2002-02-05 2007-04-17 Biesecker James L Stabilized powdered formaldehyde
CA2372261A1 (en) 2002-02-15 2003-08-15 Paul Ouellette System for measuring shrinkage behaviour and modulus change during solidification of a polymeric resin, and method therefor
US6797928B2 (en) 2002-04-23 2004-09-28 Ted Pella, Inc. Method and apparatus for the rapid decalcification and fixation of mineralized tissues
US6640625B1 (en) 2002-05-08 2003-11-04 Anthony R. H. Goodwin Method and apparatus for measuring fluid density downhole
JP3776845B2 (ja) 2002-07-02 2006-05-17 独立行政法人科学技術振興機構 組織標本の製造方法
US20040029184A1 (en) 2002-08-09 2004-02-12 Pickcell Laboratories B.V. Method for antigen retrieval and submersion fluid compositions for use therein
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
GB0304515D0 (en) * 2003-02-27 2003-04-02 Dakocytomation Denmark As Standard
US20100035254A1 (en) 2003-04-08 2010-02-11 Pacific Biosciences Of California, Inc. Composition and method for nucleic acid sequencing
US7300439B2 (en) 2003-06-24 2007-11-27 Depuy Mitek, Inc. Porous resorbable graft fixation pin
WO2005027015A2 (en) 2003-09-10 2005-03-24 Bioimagene, Inc. Method and system for quantitatively analyzing biological samples
EP1673608A4 (en) 2003-09-29 2008-05-07 Vision Biosystems Ltd SYSTEM AND METHOD FOR PROCESSING HISTOLOGICAL TISSUE SPECIMENS
WO2005054811A2 (en) 2003-11-26 2005-06-16 Separation Technology, Inc. Method and apparatus for ultrasonic determination of hematocrit and hemoglobin concentrations
DE602004018112D1 (de) 2004-06-07 2009-01-15 Milestone Srl Verfahren und Vorrichtung zur mikrowellen-unterstützten automatischen Gewebebehandlung
DE102004027919B3 (de) 2004-06-09 2006-03-30 Pfw Technologies Gmbh Verfahren zur Korrektur des Einflusses von Signalübertragungsleitungen auf Signallaufzeitänderungen bei Ultraschallmessungen
WO2006051811A1 (ja) 2004-11-10 2006-05-18 Olympus Corporation 生体観察装置
US20070016023A1 (en) 2005-06-28 2007-01-18 Siemens Medical Solutions Usa, Inc. Scalable ultrasound system and methods
WO2007016935A1 (en) 2005-07-29 2007-02-15 Histogenex Nv Methods, reagents and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies
EP1913877A1 (en) 2005-08-12 2008-04-23 Olympus Corporation Endoscope accessory, biotissue analytical processing system and method of sampling for tissue analytical processing
US20070117153A1 (en) 2005-11-23 2007-05-24 Christopher Bieniarz Molecular conjugate
US7770107B2 (en) 2006-03-01 2010-08-03 Oracle International Corporation Methods and systems for extracting and processing translatable and transformable data from XSL files
US8460859B2 (en) 2006-10-30 2013-06-11 George Mason Intellectual Properties, Inc. Tissue preservation and fixation method
US8303915B2 (en) 2006-10-30 2012-11-06 Ventana Medical Systems, Inc. Thin film apparatus and method
DK3276349T3 (da) 2006-11-01 2019-10-28 Ventana Med Syst Inc Haptener, haptenkonjugater, sammensætninger deraf og fremgangsmåder til fremstilling og anvendelse deraf
US7666620B2 (en) 2006-11-08 2010-02-23 Richard-Allan Scientific Company Rapid tissue processing system
EP1965190A1 (en) 2007-02-27 2008-09-03 Qiagen GmbH Fixation of a biological sample
JP4928989B2 (ja) 2007-03-07 2012-05-09 株式会社東芝 超音波診断装置および超音波診断装置の制御プログラム
WO2009007846A2 (en) 2007-06-15 2009-01-15 Universitetet If Oslo Methods for modifying, isolating, detecting, visualizing, and quantifying citrullinated and/or homocitrullinated peptides, polypeptides and proteins
US20090226059A1 (en) 2008-02-12 2009-09-10 Richard Levenson Tissue Processing And Assessment
JP5186256B2 (ja) 2008-03-19 2013-04-17 ユニ・チャーム株式会社 伸縮性シートの製造方法
CA2720728C (en) 2008-06-05 2018-04-03 Ventana Medical Systems, Inc. Compositions comprising nanomaterials and method for using such compositions for histochemical processes
EP2373997A1 (en) 2008-12-09 2011-10-12 Dako Denmark A/S Method for evaluating pre-treatment
WO2010080287A1 (en) 2008-12-19 2010-07-15 Ventana Medical Systems, Inc. Method and apparatus for treating slides with fluids
EP2278295A1 (en) 2009-07-24 2011-01-26 Milestone S.r.l. Single cavity tissue histology tissue-processor
WO2011071727A2 (en) 2009-12-07 2011-06-16 Wei-Sing Chu Standardization of tissue specimen preservation by ultrasound and temperature control
US10539487B2 (en) 2010-03-04 2020-01-21 Ventana Medical Systems, Inc. Systems and methods for monitoring tissue sample processing
CA2788664C (en) 2010-03-04 2023-04-11 Ventana Medical Systems, Inc. Processing system for processing specimens using acoustic energy
US10126216B2 (en) * 2011-02-17 2018-11-13 Ventana Medical Systems, Inc. Method for tissue sample fixation
US20110256530A1 (en) 2010-04-12 2011-10-20 Genvault Corporation Products and methods for tissue preservation
EP2571981A1 (en) 2010-05-20 2013-03-27 Azer Scientific, Inc. Tissue fixative having increased viscosity
EP2588443A2 (en) 2010-07-02 2013-05-08 Ventana Medical Systems, Inc. Hapten conjugates for target detection
EP2458365B1 (en) 2010-11-24 2019-04-10 Milestone S.r.l. A two-step method and system for cold formalin fixation of organic tissue samples
US9031701B2 (en) 2011-02-15 2015-05-12 Hemosonics Llc Characterization of blood hemostasis and oxygen transport parameters
MX2014002844A (es) 2011-09-13 2014-07-09 Koninkl Philips Nv Sistema y kit para preparar una muestra citologica para examen.
CA2896535A1 (en) 2012-12-28 2014-07-03 Beckman Coulter, Inc. Compositions for permeabilising fixed blood cells and uses thereof
EP3234581B1 (en) 2014-12-17 2020-09-23 Ventana Medical Systems, Inc. Obtaining a diffusivity constant
EP3234583B1 (en) 2014-12-17 2020-08-19 Ventana Medical Systems, Inc. Diffusion monitoring protocol for optimized tissue fixation

Also Published As

Publication number Publication date
CA2822532C (en) 2017-01-24
CN103518127B (zh) 2016-11-09
JP2014505890A (ja) 2014-03-06
AU2012216987B2 (en) 2014-12-11
WO2012110646A1 (en) 2012-08-23
US10126216B2 (en) 2018-11-13
US11624684B2 (en) 2023-04-11
US20120214195A1 (en) 2012-08-23
CN103518127A (zh) 2014-01-15
CA2822532A1 (en) 2012-08-23
JP5662593B2 (ja) 2015-02-04
US12158401B2 (en) 2024-12-03
ES2791725T3 (es) 2020-11-05
AU2012216987A1 (en) 2013-07-11
EP2676118B1 (en) 2020-03-18
US20190086300A1 (en) 2019-03-21
US20230194395A1 (en) 2023-06-22
EP2676118A1 (en) 2013-12-25

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