[go: up one dir, main page]

CY2017025I2 - Αντιδοτα αντιπηκτικων - Google Patents

Αντιδοτα αντιπηκτικων

Info

Publication number
CY2017025I2
CY2017025I2 CY2017025C CY2017025C CY2017025I2 CY 2017025 I2 CY2017025 I2 CY 2017025I2 CY 2017025 C CY2017025 C CY 2017025C CY 2017025 C CY2017025 C CY 2017025C CY 2017025 I2 CY2017025 I2 CY 2017025I2
Authority
CY
Cyprus
Prior art keywords
anticoagulants
antibodies
Prior art date
Application number
CY2017025C
Other languages
English (en)
Other versions
CY2017025I1 (el
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42061991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2017025(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CY2017025I1 publication Critical patent/CY2017025I1/el
Publication of CY2017025I2 publication Critical patent/CY2017025I2/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39583Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626Diabody or triabody
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CY2017025C 2010-01-20 2017-07-10 Αντιδοτα αντιπηκτικων CY2017025I2 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP10151239 2010-01-20
US38391410P 2010-09-17 2010-09-17
PCT/EP2011/050749 WO2011089183A2 (en) 2010-01-20 2011-01-20 Anticoagulant antidotes
EP11703410.8A EP2525812B1 (en) 2010-01-20 2011-01-20 Anticoagulant antidotes

Publications (2)

Publication Number Publication Date
CY2017025I1 CY2017025I1 (el) 2017-11-14
CY2017025I2 true CY2017025I2 (el) 2017-11-14

Family

ID=42061991

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20171100361T CY1118875T1 (el) 2010-01-20 2017-03-22 Αντιδοτα αντιπηκτικων
CY2017025C CY2017025I2 (el) 2010-01-20 2017-07-10 Αντιδοτα αντιπηκτικων

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20171100361T CY1118875T1 (el) 2010-01-20 2017-03-22 Αντιδοτα αντιπηκτικων

Country Status (43)

Country Link
US (3) US8486398B2 (el)
EP (2) EP3195876A1 (el)
JP (2) JP5575923B2 (el)
KR (1) KR101781787B1 (el)
CN (1) CN102711813B (el)
AP (1) AP2012006242A0 (el)
AR (1) AR079944A1 (el)
AU (1) AU2011208719C1 (el)
BR (1) BR112012018021B1 (el)
CA (1) CA2787566A1 (el)
CO (1) CO6571889A2 (el)
CY (2) CY1118875T1 (el)
DK (1) DK2525812T3 (el)
EA (1) EA028371B1 (el)
EC (1) ECSP12012105A (el)
ES (1) ES2614992T3 (el)
FR (1) FR17C1026I2 (el)
GE (1) GEP20156341B (el)
HR (1) HRP20170613T1 (el)
HU (2) HUE032263T2 (el)
IL (1) IL219427B (el)
LT (2) LT2525812T (el)
LU (1) LUC00028I2 (el)
MA (1) MA33936B1 (el)
ME (1) ME02602B (el)
MX (1) MX2012008360A (el)
MY (1) MY162323A (el)
NL (1) NL300882I2 (el)
NO (2) NO2017034I1 (el)
NZ (1) NZ599508A (el)
PE (1) PE20121516A1 (el)
PH (1) PH12012501493A1 (el)
PL (1) PL2525812T3 (el)
PT (1) PT2525812T (el)
RS (1) RS55683B1 (el)
SG (1) SG182552A1 (el)
SI (1) SI2525812T1 (el)
TN (1) TN2012000366A1 (el)
TW (1) TWI513466B (el)
UA (1) UA110470C2 (el)
UY (1) UY33196A (el)
WO (1) WO2011089183A2 (el)
ZA (1) ZA201202876B (el)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI513466B (zh) * 2010-01-20 2015-12-21 Boehringer Ingelheim Int 抗凝血劑解毒劑
CA3027071A1 (en) 2011-01-14 2013-07-19 The Regents Of The University Of California Therapeutic antibodies against ror-1 protein and methods for use of same
JP2014506448A (ja) * 2011-01-19 2014-03-17 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 凝固因子の阻害剤に対する結合タンパク質
CA2827787A1 (en) 2011-03-30 2012-10-04 Boehringer Ingelheim International Gmbh Anticoagulant antidotes
PE20141295A1 (es) 2011-11-29 2014-10-01 Perosphere Inc Agentes de reversion anticoagulante
HK1215261A1 (zh) 2013-03-14 2016-08-19 Bayer Healthcare Llc 針對與肝素複合的抗凝血酶β的單克隆抗體
EP3060583A1 (en) * 2013-10-25 2016-08-31 Boehringer Ingelheim International GmbH Anticoagulant antidotes
TW201623331A (zh) * 2014-03-12 2016-07-01 普羅帝納生物科學公司 抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法
CN105223348A (zh) * 2014-05-26 2016-01-06 北京九强生物技术股份有限公司 人抗凝血酶iii的胶乳增强免疫比浊法检测试剂盒
EP2980218A1 (en) * 2014-07-30 2016-02-03 Rheinische Friedrich-Wilhelms-Universität Bonn Aptamer thrombin complex for use as an antidote to direct acting thrombin inhibitors
EP3611507B1 (en) * 2014-07-31 2021-11-24 Haemonetics Corporation Detection of reversal of an anticoagulant using ecarin and factor xa clotting assays
WO2016044645A1 (en) * 2014-09-17 2016-03-24 Elmaleh David R Anticoagulant derivatives for cardiovascular imaging
WO2016107605A1 (zh) 2014-12-31 2016-07-07 昆明积大制药股份有限公司 药物组合物及其制备方法
US10449195B2 (en) 2016-03-29 2019-10-22 Shenzhen Pharmacin Co., Ltd. Pharmaceutical formulation of palbociclib and a preparation method thereof
US11879014B2 (en) 2017-03-17 2024-01-23 Tusk Therapeutics Ltd. Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody
JP7233720B2 (ja) * 2017-12-24 2023-03-07 ノイルイミューン・バイオテック株式会社 ヒトメソセリンを特異的に認識する細胞表面分子、il-7、及びccl19を発現する免疫担当細胞
SG11202008733YA (en) 2018-03-13 2020-10-29 Tusk Therapeutics Ltd Anti-cd25 for tumour specific cell depletion
KR20210039985A (ko) * 2018-05-11 2021-04-12 헬시언 테라퓨틱스 인코포레이티드 Gasp-1 과립을 표적으로 하는 결합 단백질 및 키메라 항원 수용체 t 세포, 및 이의 용도
CN113195515B (zh) 2018-10-29 2024-11-15 丽珠医药集团股份有限公司 新的二肽类化合物及其用途
US12251377B2 (en) 2019-03-06 2025-03-18 University Of Rochester Anticoagulant compositions and uses thereof
CN114306245A (zh) 2020-09-29 2022-04-12 深圳市药欣生物科技有限公司 无定形固体分散体的药物组合物及其制备方法
TW202321311A (zh) * 2021-08-02 2023-06-01 日商諾伊爾免疫生物科技股份有限公司 與scFv等之連接子結合的抗體
US11446286B1 (en) * 2022-02-28 2022-09-20 King Faisal University Treatment of fungal infections using dabigatran etexilate
NL2036011B1 (en) 2023-10-12 2025-04-30 Synapse Res Institute Molecules for reversing anti-coagulant activity of direct oral anticoagulants
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087380A (en) 1949-11-24 2000-07-11 Boehringer Ingelheim Pharma Kg Disubstituted bicyclic heterocycles, the preparations and the use thereof as pharmaceutical compositions
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
ATE102631T1 (de) 1988-11-11 1994-03-15 Medical Res Council Klonierung von immunglobulin sequenzen aus den variabelen domaenen.
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
EP0654085B1 (en) * 1992-01-23 1997-04-02 MERCK PATENT GmbH Monomeric and dimeric antibody-fragment fusion proteins
DE4203965A1 (de) 1992-02-11 1993-08-12 Max Planck Gesellschaft Antidot fuer hirudin und synthetische thrombininhibitoren
DE69330523D1 (de) 1992-08-21 2001-09-06 Vrije Universiteit Brussel Bru Immunoglobuline ohne leichte ketten
DK0672142T3 (da) 1992-12-04 2001-06-18 Medical Res Council Multivalente og multispecifikke bindingsproteiner samt fremstilling og anvendelse af disse
CA2163032C (en) 1993-06-03 2001-02-06 John Landon Antibody fragments in therapy
AT404357B (de) 1995-06-13 1998-11-25 Immuno Ag Prothrombin-derivate
DE19605126A1 (de) 1996-02-12 1997-08-14 Basf Ag Thrombinmuteine als Antidot für Thrombininhibitoren
US6200955B1 (en) 1996-06-11 2001-03-13 Commonwealth Biotechnologies, Inc. Heparin binding peptides
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
PE121699A1 (es) 1997-02-18 1999-12-08 Boehringer Ingelheim Pharma Heterociclos biciclicos disustituidos como inhibidores de la trombina
WO1998049198A1 (en) 1997-04-30 1998-11-05 Enzon, Inc. Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof
DE19729544A1 (de) * 1997-07-10 1999-01-14 Basf Ag Ancrod spezifische monoklonale Antikörper, Antikörperfragmente, deren Mischung oder Derivate und deren Verwendung
US6440417B1 (en) 1998-11-06 2002-08-27 Conjuchem, Inc. Antibodies to argatroban derivatives and their use in therapeutic and diagnostic treatments
US6624141B1 (en) 1999-03-17 2003-09-23 The Regents Of The University Of Michigan Protamine fragment compositions and methods of use
EP2275557A1 (en) 2000-04-12 2011-01-19 Human Genome Sciences, Inc. Albumin fusion proteins
EP2316951A1 (en) 2001-01-17 2011-05-04 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20040097547A1 (en) 2001-04-16 2004-05-20 Taveras Arthur G. 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20070031438A1 (en) * 2001-12-10 2007-02-08 Junghans Richard P Antibodies as chimeric effector cell receptors against tumor antigens
AU2002351896A1 (en) 2001-12-11 2003-06-23 Ablynx N.V. Method for displaying loops from immunoglobulin domains in different contexts
AU2003244817B2 (en) 2002-06-28 2010-08-26 Domantis Limited Antigen-binding immunoglobulin single variable domains and dual-specific constructs
JP2006519763A (ja) 2002-11-08 2006-08-31 アブリンクス エン.ヴェー. 治療用ポリペプチドの投与法およびそのためのポリペプチド
DE602004017726D1 (de) 2003-06-30 2008-12-24 Domantis Ltd Pegylierte Single-domain-antikörper (dAb)
DK2915564T3 (da) 2007-09-28 2021-02-08 Alexion Pharma Inc Antidoter mod faktor XA-inhibitorer og fremgangsmåder til anvendelse deraf
AR070141A1 (es) * 2008-01-23 2010-03-17 Glenmark Pharmaceuticals Sa Anticuerpos humanizados especificos para el factor von willebrand
BR112012004169A2 (pt) 2009-08-24 2016-03-29 Boehringer Ingelheim Int intervenções de emergência com carvão vegetal ativado em superdosagem de etexilato de dabigatran
TWI513466B (zh) * 2010-01-20 2015-12-21 Boehringer Ingelheim Int 抗凝血劑解毒劑

Also Published As

Publication number Publication date
MY162323A (en) 2017-05-31
SI2525812T1 (sl) 2017-05-31
CO6571889A2 (es) 2012-11-30
PE20121516A1 (es) 2012-11-24
FR17C1026I1 (fr) 2017-09-08
LTPA2017021I1 (lt) 2017-07-25
AU2011208719C1 (en) 2017-07-13
US8486398B2 (en) 2013-07-16
US20130289248A1 (en) 2013-10-31
NZ599508A (en) 2014-05-30
PH12012501493A1 (en) 2012-10-22
HUE032263T2 (en) 2017-09-28
ME02602B (me) 2017-06-20
EP2525812A2 (en) 2012-11-28
UA110470C2 (ru) 2016-01-12
DK2525812T3 (en) 2017-02-27
HK1173957A1 (en) 2013-05-31
PT2525812T (pt) 2017-04-26
WO2011089183A2 (en) 2011-07-28
TN2012000366A1 (en) 2014-01-30
AP2012006242A0 (en) 2012-04-30
MA33936B1 (fr) 2013-01-02
HRP20170613T1 (hr) 2017-06-30
TW201136606A (en) 2011-11-01
US20120027780A1 (en) 2012-02-02
CY1118875T1 (el) 2018-01-10
CN102711813A (zh) 2012-10-03
CY2017025I1 (el) 2017-11-14
US9034822B2 (en) 2015-05-19
US20150210778A1 (en) 2015-07-30
LTC2525812I2 (lt) 2019-05-10
ECSP12012105A (es) 2012-10-30
BR112012018021A2 (pt) 2017-06-20
CN102711813B (zh) 2015-03-04
PL2525812T3 (pl) 2017-07-31
KR20120128126A (ko) 2012-11-26
LUC00028I1 (el) 2017-07-14
EP3195876A1 (en) 2017-07-26
HUS1700030I1 (hu) 2017-08-28
JP5575923B2 (ja) 2014-08-20
CA2787566A1 (en) 2011-07-28
NO2022036I1 (no) 2022-08-12
EA201201016A1 (ru) 2013-02-28
EA028371B1 (ru) 2017-11-30
AU2011208719A1 (en) 2012-05-17
ZA201202876B (en) 2012-12-27
UY33196A (es) 2011-08-31
NO2017034I1 (no) 2017-07-11
IL219427B (en) 2018-05-31
TWI513466B (zh) 2015-12-21
JP2014210794A (ja) 2014-11-13
FR17C1026I2 (fr) 2018-07-20
LUC00028I2 (el) 2017-09-25
EP2525812B1 (en) 2017-01-18
NL300882I2 (nl) 2017-07-20
JP2013517317A (ja) 2013-05-16
KR101781787B1 (ko) 2017-09-26
ES2614992T3 (es) 2017-06-02
LT2525812T (lt) 2017-02-27
MX2012008360A (es) 2012-08-08
WO2011089183A3 (en) 2011-11-17
IL219427A0 (en) 2012-06-28
AR079944A1 (es) 2012-02-29
RS55683B1 (sr) 2017-07-31
SG182552A1 (en) 2012-08-30
GEP20156341B (en) 2015-08-10
BR112012018021B1 (pt) 2020-12-08

Similar Documents

Publication Publication Date Title
HUS2300021I1 (hu) Anti-IL-36R antitestek
CY2017025I2 (el) Αντιδοτα αντιπηκτικων
CY2019040I1 (el) Aνti-il-23 αντισωματα
LTC2579894I2 (lt) CGRP antikūnai
HUE056313T2 (hu) Anti-DLL3 antitest
BR112012030311A2 (pt) anticorpo
IL222272B (en) Anti-erbb3 antibodies
DK3741883T3 (da) Antistofbiblioteker
DK3284754T3 (da) Anti-cd38-antistoffer
DK2521736T3 (da) Humaniserede antistoffer
HRP20181320T8 (hr) Ljudska anti-tau protutijela
CO6791565A2 (es) Anticuerpos anti-notch1
DK3178851T3 (da) Anti-cd40-antistoffer
CR20130228A (es) Anticuerpos neutralizadores anti-ccl20
LT3275896T (lt) Antikūnų gavimo procesas
PT2736340T (pt) Biocontrolo de nemátodos
DK3202789T3 (da) Anti-vla-4-antistoffer
IL225346B (en) Serum preparation
HUE043576T2 (hu) Antitestek notum pektinacetilészterázhoz
EP2578316A4 (en) PIPETTE
CO6841994A2 (es) Anticuerpos
FR2956419B1 (fr) Elements de construction calorifuges
FR2955136B1 (fr) Arret de vantail
UA21042S (uk) Комплект бланків
IT1400965B1 (it) Polimorfi di fexofenadina