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DK2189446T3 - Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller - Google Patents

Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller

Info

Publication number
DK2189446T3
DK2189446T3 DK08790795.2T DK08790795T DK2189446T3 DK 2189446 T3 DK2189446 T3 DK 2189446T3 DK 08790795 T DK08790795 T DK 08790795T DK 2189446 T3 DK2189446 T3 DK 2189446T3
Authority
DK
Denmark
Prior art keywords
benzadimine
butoxycarbonylimino
butoxycarbonyl
piperidinyl
propoxy
Prior art date
Application number
DK08790795.2T
Other languages
English (en)
Inventor
Junichi Mitsuyama
Naokatu Aoki
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2189446T3 publication Critical patent/DK2189446T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK08790795.2T 2007-07-04 2008-07-02 Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller DK2189446T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007176106 2007-07-04
PCT/JP2008/061944 WO2009005077A1 (ja) 2007-07-04 2008-07-02 ４－｛３－［４－（３－｛４－［アミノ（ブトキシカルボニルイミノ）メチル］フェノキシ｝プロピル）－１－ピペリジニル］プロポキシ｝－ｎ’－（ブトキシカルボニル）ベンズアミジンの新規な結晶

Publications (1)

Publication Number Publication Date
DK2189446T3 true DK2189446T3 (da) 2012-09-24

Family

ID=40226120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08790795.2T DK2189446T3 (da) 2007-07-04 2008-07-02 Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller

Country Status (22)

Country Link
US (1) US8158800B2 (da)
EP (1) EP2189446B1 (da)
JP (1) JP5261386B2 (da)
KR (1) KR20100027176A (da)
CN (1) CN101730682B (da)
AU (1) AU2008272124B2 (da)
BR (1) BRPI0813104A2 (da)
CA (1) CA2691954C (da)
CY (1) CY1113210T1 (da)
DK (1) DK2189446T3 (da)
ES (1) ES2391319T3 (da)
HR (1) HRP20120796T1 (da)
IL (1) IL202804A (da)
MX (1) MX2009013913A (da)
NZ (1) NZ582187A (da)
PL (1) PL2189446T3 (da)
PT (1) PT2189446E (da)
RU (1) RU2456272C2 (da)
SI (1) SI2189446T1 (da)
TW (1) TWI395735B (da)
WO (1) WO2009005077A1 (da)
ZA (1) ZA201000027B (da)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7291617B2 (en) * 2002-03-06 2007-11-06 Toyama Chemical Co., Ltd. Arylamidine derivative or salt thereof
WO2006003881A1 (ja) * 2004-06-30 2006-01-12 Toyama Chemical Co., Ltd. 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
ZA200805604B (en) * 2005-12-29 2009-12-30 Toyama Chemical Co Ltd Novel arylamidine derivative, salt thereof and antifungal agent containing those
PT2070536E (pt) 2006-10-06 2012-03-06 Toyama Chemical Co Ltd Composição farmacêutica que contém um derivado de fenilamidina e processo para utilização dessa composição farmacêutica em associação com um agente antifúngico

Also Published As

Publication number Publication date
PT2189446E (pt) 2012-10-25
NZ582187A (en) 2011-03-31
SI2189446T1 (sl) 2012-12-31
EP2189446A4 (en) 2010-10-20
IL202804A0 (en) 2010-06-30
CA2691954A1 (en) 2009-01-08
TW200914421A (en) 2009-04-01
EP2189446B1 (en) 2012-08-22
US8158800B2 (en) 2012-04-17
CY1113210T1 (el) 2016-04-13
WO2009005077A1 (ja) 2009-01-08
EP2189446A1 (en) 2010-05-26
PL2189446T3 (pl) 2013-01-31
HRP20120796T1 (hr) 2012-10-31
JPWO2009005077A1 (ja) 2010-08-26
MX2009013913A (es) 2010-03-10
TWI395735B (zh) 2013-05-11
CA2691954C (en) 2014-10-28
ES2391319T3 (es) 2012-11-23
AU2008272124A1 (en) 2009-01-08
BRPI0813104A2 (pt) 2014-12-23
JP5261386B2 (ja) 2013-08-14
ZA201000027B (en) 2011-03-30
CN101730682A (zh) 2010-06-09
RU2456272C2 (ru) 2012-07-20
CN101730682B (zh) 2012-08-08
AU2008272124B2 (en) 2012-08-23
US20110046381A1 (en) 2011-02-24
RU2010103672A (ru) 2011-08-10
IL202804A (en) 2013-10-31
KR20100027176A (ko) 2010-03-10

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