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DK2182920T3 - Stabil væskeformig farmaceutisk komposition baseret på trazodon - Google Patents

Stabil væskeformig farmaceutisk komposition baseret på trazodon

Info

Publication number
DK2182920T3
DK2182920T3 DK08775278.8T DK08775278T DK2182920T3 DK 2182920 T3 DK2182920 T3 DK 2182920T3 DK 08775278 T DK08775278 T DK 08775278T DK 2182920 T3 DK2182920 T3 DK 2182920T3
Authority
DK
Denmark
Prior art keywords
trazodone
pharmaceutical composition
liquid pharmaceutical
composition based
stable liquid
Prior art date
Application number
DK08775278.8T
Other languages
English (en)
Inventor
Marcello Marchetti
Francesca Mariotti
Lorella Ragni
Paolo Scarpetti
Mauro Valenti
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of DK2182920T3 publication Critical patent/DK2182920T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK08775278.8T 2007-07-31 2008-07-22 Stabil væskeformig farmaceutisk komposition baseret på trazodon DK2182920T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001573A ITMI20071573A1 (it) 2007-07-31 2007-07-31 Composizione farmaceutica liquida stabile a base di trazodone
PCT/EP2008/059605 WO2009016069A2 (en) 2007-07-31 2008-07-22 Stable liquid pharmaceutical composition based on trazodone

Publications (1)

Publication Number Publication Date
DK2182920T3 true DK2182920T3 (da) 2013-03-04

Family

ID=38858941

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12170235T DK2494955T3 (da) 2007-07-31 2008-07-22 Stabil væskeformig farmaceutisk komposition baseret på tradozone.
DK08775278.8T DK2182920T3 (da) 2007-07-31 2008-07-22 Stabil væskeformig farmaceutisk komposition baseret på trazodon

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12170235T DK2494955T3 (da) 2007-07-31 2008-07-22 Stabil væskeformig farmaceutisk komposition baseret på tradozone.

Country Status (23)

Country Link
US (1) US10292931B2 (da)
EP (2) EP2182920B1 (da)
JP (1) JP5426548B2 (da)
KR (1) KR101493370B1 (da)
CN (1) CN101784257B (da)
AR (1) AR068327A1 (da)
AU (1) AU2008281858B2 (da)
CA (1) CA2692975C (da)
CY (1) CY1116189T1 (da)
DK (2) DK2494955T3 (da)
EA (1) EA016822B1 (da)
ES (2) ES2399569T3 (da)
GE (1) GEP20125525B (da)
HR (1) HRP20150349T1 (da)
IL (1) IL203167A (da)
IT (1) ITMI20071573A1 (da)
MX (1) MX2010001092A (da)
PL (2) PL2494955T3 (da)
PT (2) PT2182920E (da)
SG (1) SG183659A1 (da)
SI (2) SI2494955T1 (da)
UA (1) UA102376C2 (da)
WO (1) WO2009016069A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20071603A1 (it) 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
RU2706700C1 (ru) * 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях
GEP20257739B (en) * 2019-09-26 2025-02-25 Angelini S P A Pediatric trazodone compositions
CN111568861A (zh) * 2020-05-25 2020-08-25 河北科星药业有限公司 畜禽用盐酸溴己新口服液及其制备方法和应用
WO2024220372A1 (en) * 2023-04-15 2024-10-24 Rubicon Research Private Limited Liquid formulations of trazodone
CN119280155B (zh) * 2024-12-11 2025-02-25 新基元(北京)医药科技有限公司 一种改善稳定性的盐酸曲唑酮液体药物组合物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154832A (en) 1974-08-26 1979-05-15 Bruno Silvestrini Novel treatment for acute organic cerebral syndromes (strokes)
IT1233412B (it) * 1987-12-02 1992-03-30 Acraf Uso del trazodone
ATE292956T1 (de) * 1998-07-24 2005-04-15 Seo Hong Yoo Klare wässrige lösungen enthaltend gallensäuren
AU2003903597A0 (en) 2003-07-11 2003-07-24 Jakov Vaisman Treatment of premature ejaculation
ITMI20071603A1 (it) 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata

Also Published As

Publication number Publication date
HRP20150349T1 (hr) 2015-05-22
EP2182920B1 (en) 2012-12-26
DK2494955T3 (da) 2015-04-13
AU2008281858B2 (en) 2014-02-27
PL2494955T3 (pl) 2015-06-30
HK1176280A1 (en) 2013-07-26
CN101784257B (zh) 2012-11-28
EA201070194A1 (ru) 2010-06-30
KR101493370B1 (ko) 2015-02-13
US10292931B2 (en) 2019-05-21
JP5426548B2 (ja) 2014-02-26
ITMI20071573A1 (it) 2009-02-01
EP2494955A3 (en) 2012-10-03
WO2009016069A4 (en) 2009-05-14
BRPI0814658A2 (pt) 2015-02-18
SI2182920T1 (sl) 2013-04-30
PT2494955E (pt) 2015-03-04
IL203167A (en) 2017-08-31
PL2182920T3 (pl) 2013-05-31
CN101784257A (zh) 2010-07-21
AU2008281858A1 (en) 2009-02-05
ES2531241T3 (es) 2015-03-12
EP2494955B1 (en) 2015-01-21
GEP20125525B (en) 2012-05-25
HK1138207A1 (en) 2010-08-20
MX2010001092A (es) 2010-03-01
EP2494955A2 (en) 2012-09-05
SG183659A1 (en) 2012-09-27
WO2009016069A3 (en) 2009-03-19
KR20100038112A (ko) 2010-04-12
EP2182920A2 (en) 2010-05-12
ES2399569T3 (es) 2013-04-02
CY1116189T1 (el) 2017-02-08
SI2494955T1 (sl) 2015-04-30
CA2692975A1 (en) 2009-02-05
AR068327A1 (es) 2009-11-11
CA2692975C (en) 2016-01-12
EA016822B1 (ru) 2012-07-30
WO2009016069A2 (en) 2009-02-05
JP2010534703A (ja) 2010-11-11
US20100256159A1 (en) 2010-10-07
PT2182920E (pt) 2013-03-07
UA102376C2 (ru) 2013-07-10

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