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DK2089371T3 - Fremstillingsmåde til fremstilling af hexahydrofuro[2,3-b]furan-3-OL - Google Patents

Fremstillingsmåde til fremstilling af hexahydrofuro[2,3-b]furan-3-OL

Info

Publication number
DK2089371T3
DK2089371T3 DK07822416.9T DK07822416T DK2089371T3 DK 2089371 T3 DK2089371 T3 DK 2089371T3 DK 07822416 T DK07822416 T DK 07822416T DK 2089371 T3 DK2089371 T3 DK 2089371T3
Authority
DK
Denmark
Prior art keywords
hexahydrofuro
furan
preparation
preparing
methods
Prior art date
Application number
DK07822416.9T
Other languages
English (en)
Inventor
Sebastien Francois Emmanuel Lemaire
Andras Horvath
Wim Albert Alex Aelterman
Thomas Joachim Landewald Rammeloo
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37692659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2089371(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Application granted granted Critical
Publication of DK2089371T3 publication Critical patent/DK2089371T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK07822416.9T 2006-11-09 2007-11-09 Fremstillingsmåde til fremstilling af hexahydrofuro[2,3-b]furan-3-OL DK2089371T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06123752 2006-11-09
PCT/EP2007/062119 WO2008055970A2 (en) 2006-11-09 2007-11-09 Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol

Publications (1)

Publication Number Publication Date
DK2089371T3 true DK2089371T3 (da) 2011-05-16

Family

ID=37692659

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07822416.9T DK2089371T3 (da) 2006-11-09 2007-11-09 Fremstillingsmåde til fremstilling af hexahydrofuro[2,3-b]furan-3-OL

Country Status (22)

Country Link
US (1) US8153829B2 (da)
EP (1) EP2089371B1 (da)
JP (1) JP5491862B2 (da)
CN (2) CN101541775B (da)
AT (1) ATE497499T1 (da)
AU (1) AU2007316562B2 (da)
BR (1) BRPI0718706B8 (da)
CA (1) CA2669014C (da)
CY (1) CY1111407T1 (da)
DE (1) DE602007012365D1 (da)
DK (1) DK2089371T3 (da)
ES (1) ES2359949T3 (da)
HR (1) HRP20110258T1 (da)
IL (1) IL198270A (da)
ME (1) ME01232B (da)
MX (1) MX2009004957A (da)
PL (1) PL2089371T3 (da)
PT (1) PT2089371E (da)
RS (1) RS51675B (da)
RU (1) RU2464266C2 (da)
SI (1) SI2089371T1 (da)
WO (1) WO2008055970A2 (da)

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US9062065B2 (en) 2009-10-30 2015-06-23 Lupin Limited Process for preparation of darunavir and darunavir ethanolate of fine particle size
US20110313035A1 (en) 2009-12-16 2011-12-22 Hetero Research Foundation Polymorphs of darunavir
ES2516916T3 (es) 2010-01-28 2014-10-31 Mapi Pharma Limited Procedimiento para la preparación de darunavir e intermedios de darunavir
US8853430B2 (en) 2010-05-20 2014-10-07 Hetero Research Foundation Crystalline hydrochloride salt of darunavir
CN102617586B (zh) * 2011-01-26 2016-04-06 浙江九洲药业股份有限公司 地瑞那韦中间体的制备方法
EP2887807B1 (en) 2012-08-22 2019-09-18 Merck Sharp & Dohme Corp. Benzimidazole hexahydrofuro[3,2-b]furan derivatives useful as amp-activated protein kinase activators
CN103864813B (zh) * 2012-12-18 2017-02-22 上海迪赛诺化学制药有限公司 一种合成六氢呋喃并[2,3‑b]呋喃‑3‑醇及其对映体的方法
CN103896886A (zh) * 2012-12-31 2014-07-02 上海迪赛诺化学制药有限公司 一种达鲁那韦中间体及其制备方法和应用
TW201514188A (zh) * 2013-03-13 2015-04-16 Lantheus Medical Imaging Inc 製備釓磷維塞三鈉單水合物之方法
CN103664976B (zh) * 2013-12-12 2015-11-04 惠州市莱佛士制药技术有限公司 一种顺式六氢呋喃并[2,3-b]呋喃-3-醇的制备方法
CN107344944B (zh) * 2016-05-07 2021-03-05 成都博腾药业有限公司 一种制备地瑞那韦中间体的方法
CN112300186B (zh) * 2019-08-01 2024-04-30 浙江九洲药业股份有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法

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DE69512220T2 (de) 1994-03-07 2000-03-16 Vertex Pharmaceuticals Inc. Sulfonamidderivate als aspartylprotease-inhibitoren
JP3665343B2 (ja) 1995-02-03 2005-06-29 株式会社カネカ α−ハロケトン、α−ハロヒドリン及びエポキシドの製造法
CA2236236A1 (en) 1995-11-15 1997-05-22 G.D. Searle & Co. Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US5856531A (en) * 1996-10-21 1999-01-05 Eastman Chemical Company Preparation of 3-methytetra-hydrofuran from 2,3-dihydrofuran
JP2002515888A (ja) * 1996-10-21 2002-05-28 イーストマン ケミカル カンパニー 3―アルキルテトラヒドロフランの製造方法
US5990313A (en) * 1996-10-21 1999-11-23 Eastman Chemical Company Preparation of 3-alkyltetrahydrofurans
PT1086076E (pt) 1998-06-19 2005-05-31 Vertex Pharma Inibidores de sulfonamida de aspartil protease
WO1999067254A2 (en) 1998-06-23 1999-12-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Multi-drug resistant retroviral protease inhibitors and use thereof
ES2362404T5 (es) 1998-06-23 2015-11-25 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Ensayo de aptitud y métodos para reducir la resistencia del VIH a terapia
ATE269314T1 (de) 1998-08-25 2004-07-15 Kaneka Corp Verfahren zur herstellung von (2r, 3s)-amino-1,2- oxiran
US6344572B1 (en) 1999-01-29 2002-02-05 Kaneka Corporation Processes for the preparation of threo-1,2-epoxy-3-amino-4-phenylbutane derivatives
WO2000047551A2 (en) 1999-02-12 2000-08-17 Vertex Pharmaceuticals Incorporated Inhibitors of aspartyl protease
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KR100708221B1 (ko) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
PL204924B1 (pl) 1999-10-06 2010-02-26 Tibotec Pharm Ltd Heksahydrofuro [2,3-b] furanylo-3-N-{3(1,3-benzodioksolilo-5-sulfonylo) (izobutylo) amino] -1-benzylo-2-hydroksypropylo} karbaminian oraz jego zastosowanie
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CN100519561C (zh) * 2001-09-10 2009-07-29 泰博特克药品有限公司 制备六氢-呋喃并[2,3-b]呋喃-3-醇的方法
ATE335745T1 (de) 2001-09-20 2006-09-15 Smithkline Beecham Corp Verfahren zur herstellung von protease hemmenden zwischenprodukten
SI2314591T2 (sl) * 2002-05-16 2021-08-31 Janssen Sciences Ireland Unlimited Company Psevdopolimorfne oblike zaviralca HIV proteaze
ES2268427T3 (es) 2002-06-27 2007-03-16 Smithkline Beecham Corporation Preparacion de estereoisomeros de (3alfa, 3alfa/beta, 6alfa/beta) hexahidrofuro(2,3-b)furan-3-ol.
AU2003287038A1 (en) 2002-10-09 2004-05-04 The Board Of Trustees Of The University Of Illinois METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO (2, 3-b) FURAN AND RELATED COMPOUNDS
AU2003275675A1 (en) 2002-12-27 2004-07-29 Sumitomo Chemical Company, Limited Process for producing hexahydrofurofuranol derivative, intermediate thereof and process for producing the same
KR101192859B1 (ko) * 2003-12-23 2012-10-19 얀센 알 앤드 디 아일랜드 (3r,3as,6ar)-헥사하이드로푸로〔2,3-b〕푸란-3-일(1s,2r)-3-〔〔(4-아미노페닐)설포닐〕(이소부틸)아미노〕-1-벤질-2-하이드록시프로필카바메이트의 제조방법
TWI383975B (zh) 2004-03-31 2013-02-01 悌柏泰克醫藥有限公司 製備(3R,3aS,6aR)六氫-呋喃并〔2,3-b〕呋喃-3-醇之方法

Also Published As

Publication number Publication date
CA2669014A1 (en) 2008-05-15
DE602007012365D1 (de) 2011-03-17
BRPI0718706B1 (pt) 2021-03-23
RU2009121792A (ru) 2010-12-20
PL2089371T3 (pl) 2011-06-30
AU2007316562B2 (en) 2013-02-21
PT2089371E (pt) 2011-04-18
IL198270A0 (en) 2009-12-24
CN101541775B (zh) 2011-12-28
BRPI0718706B8 (pt) 2021-05-25
US20100094028A1 (en) 2010-04-15
ES2359949T3 (es) 2011-05-30
WO2008055970A3 (en) 2008-06-26
ATE497499T1 (de) 2011-02-15
CY1111407T1 (el) 2015-08-05
MX2009004957A (es) 2009-05-19
WO2008055970A2 (en) 2008-05-15
IL198270A (en) 2014-02-27
RU2464266C2 (ru) 2012-10-20
RS51675B (sr) 2011-10-31
CN101541775A (zh) 2009-09-23
EP2089371B1 (en) 2011-02-02
AU2007316562A1 (en) 2008-05-15
CN102432621A (zh) 2012-05-02
BRPI0718706A2 (pt) 2014-01-07
CN102432621B (zh) 2016-02-17
HRP20110258T1 (hr) 2011-05-31
SI2089371T1 (sl) 2011-05-31
US8153829B2 (en) 2012-04-10
EP2089371A2 (en) 2009-08-19
JP5491862B2 (ja) 2014-05-14
JP2010509290A (ja) 2010-03-25
CA2669014C (en) 2016-01-26
ME01232B (me) 2013-06-20

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