DK1917254T3 - Fermgangsmåde til fremstilling af Amorolfin - Google Patents
Fermgangsmåde til fremstilling af AmorolfinInfo
- Publication number
- DK1917254T3 DK1917254T3 DK06809226T DK06809226T DK1917254T3 DK 1917254 T3 DK1917254 T3 DK 1917254T3 DK 06809226 T DK06809226 T DK 06809226T DK 06809226 T DK06809226 T DK 06809226T DK 1917254 T3 DK1917254 T3 DK 1917254T3
- Authority
- DK
- Denmark
- Prior art keywords
- amorolfine
- preparing
- procedure
- preparing amorolfine
- Prior art date
Links
- MQHLMHIZUIDKOO-OKZBNKHCSA-N (2R,6S)-2,6-dimethyl-4-[(2S)-2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine Chemical compound C1=CC(C(C)(C)CC)=CC=C1C[C@H](C)CN1C[C@@H](C)O[C@@H](C)C1 MQHLMHIZUIDKOO-OKZBNKHCSA-N 0.000 title 1
- 229960003204 amorolfine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05291612A EP1749825A1 (fr) | 2005-07-28 | 2005-07-28 | Procédé pour la préparation d' amorolfine |
| PCT/IB2006/003210 WO2007012983A2 (fr) | 2005-07-28 | 2006-07-27 | Procede de production d'amorolfine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1917254T3 true DK1917254T3 (da) | 2009-03-16 |
Family
ID=35044548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06809226T DK1917254T3 (da) | 2005-07-28 | 2006-07-27 | Fermgangsmåde til fremstilling af Amorolfin |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090163711A1 (fr) |
| EP (2) | EP1749825A1 (fr) |
| JP (1) | JP2009502901A (fr) |
| AR (1) | AR057087A1 (fr) |
| AT (1) | ATE417839T1 (fr) |
| BR (1) | BRPI0606197B8 (fr) |
| CA (1) | CA2601149C (fr) |
| CY (1) | CY1108884T1 (fr) |
| DE (1) | DE602006004360D1 (fr) |
| DK (1) | DK1917254T3 (fr) |
| ES (1) | ES2319819T3 (fr) |
| PL (1) | PL1917254T3 (fr) |
| PT (1) | PT1917254E (fr) |
| SI (1) | SI1917254T1 (fr) |
| WO (1) | WO2007012983A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1935889A1 (fr) * | 2006-12-21 | 2008-06-25 | Galderma S.A. | Procédé de production d'amorolfine |
| JP5502890B2 (ja) | 2008-12-04 | 2014-05-28 | エフ．ホフマン−ラ ロシュ アーゲー | ピリダジノン誘導体 |
| ITFI20090032A1 (it) | 2009-02-20 | 2010-08-21 | Synteco S P A Prodotti Di Sintesi Per L Ind | Processo di produzione industriale dell'amorolfina cloridrato |
| WO2011003455A1 (fr) * | 2009-07-09 | 2011-01-13 | Cilag Ag | Procédé pour préparer des composés de 4-(alkyl)-1-(2-méthyl-3-(2,6-diméthylmorpholin)propyl)benzène |
| WO2011066735A1 (fr) * | 2009-12-01 | 2011-06-09 | Zhejiang Hisoar Pharmaceutical Co., Ltd | Cristal d'amorolfine hcl et son procédé de fabrication |
| CN108997246B (zh) * | 2017-06-06 | 2021-08-31 | 江苏礼华生物技术有限公司 | 盐酸阿莫罗芬的制备方法 |
| CN109232458A (zh) * | 2018-06-15 | 2019-01-18 | 南通常佑药业科技有限公司 | 一种手性吗啉化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0008686B1 (fr) * | 1978-08-08 | 1983-04-20 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Procédé de préparation de dérivés de phényl-propyl-morpholine et -pipéridine |
| ZW15780A1 (en) * | 1979-08-17 | 1981-03-18 | Hoffmann La Roche | Heterocyclic compounds |
| FR2589858A1 (fr) * | 1985-11-14 | 1987-05-15 | Exxon Production Research Co | Procede d'alkylation selective de composes aromatiques |
-
2005
- 2005-07-28 EP EP05291612A patent/EP1749825A1/fr not_active Withdrawn
-
2006
- 2006-07-27 AT AT06809226T patent/ATE417839T1/de active
- 2006-07-27 DK DK06809226T patent/DK1917254T3/da active
- 2006-07-27 EP EP06809226A patent/EP1917254B1/fr active Active
- 2006-07-27 BR BRPI0606197A patent/BRPI0606197B8/pt active IP Right Grant
- 2006-07-27 US US11/795,033 patent/US20090163711A1/en not_active Abandoned
- 2006-07-27 AR ARP060103246A patent/AR057087A1/es not_active Application Discontinuation
- 2006-07-27 ES ES06809226T patent/ES2319819T3/es active Active
- 2006-07-27 CA CA2601149A patent/CA2601149C/fr not_active Expired - Fee Related
- 2006-07-27 DE DE602006004360T patent/DE602006004360D1/de active Active
- 2006-07-27 PL PL06809226T patent/PL1917254T3/pl unknown
- 2006-07-27 SI SI200630146T patent/SI1917254T1/sl unknown
- 2006-07-27 JP JP2008523486A patent/JP2009502901A/ja not_active Withdrawn
- 2006-07-27 PT PT06809226T patent/PT1917254E/pt unknown
- 2006-07-27 WO PCT/IB2006/003210 patent/WO2007012983A2/fr not_active Ceased
-
2009
- 2009-03-17 CY CY20091100295T patent/CY1108884T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1108884T1 (el) | 2014-07-02 |
| BRPI0606197B8 (pt) | 2021-05-25 |
| BRPI0606197A2 (pt) | 2009-06-02 |
| EP1749825A1 (fr) | 2007-02-07 |
| EP1917254B1 (fr) | 2008-12-17 |
| CA2601149C (fr) | 2011-01-04 |
| PT1917254E (pt) | 2009-02-23 |
| JP2009502901A (ja) | 2009-01-29 |
| SI1917254T1 (sl) | 2009-04-30 |
| CA2601149A1 (fr) | 2007-02-01 |
| WO2007012983A2 (fr) | 2007-02-01 |
| DE602006004360D1 (de) | 2009-01-29 |
| ATE417839T1 (de) | 2009-01-15 |
| BRPI0606197B1 (pt) | 2021-03-30 |
| AR057087A1 (es) | 2007-11-14 |
| ES2319819T3 (es) | 2009-05-12 |
| US20090163711A1 (en) | 2009-06-25 |
| PL1917254T3 (pl) | 2009-06-30 |
| EP1917254A2 (fr) | 2008-05-07 |
| WO2007012983A3 (fr) | 2007-05-03 |
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