SI1917254T1 - Postopek izdelave amorolfina - Google Patents
Postopek izdelave amorolfinaInfo
- Publication number
- SI1917254T1 SI1917254T1 SI200630146T SI200630146T SI1917254T1 SI 1917254 T1 SI1917254 T1 SI 1917254T1 SI 200630146 T SI200630146 T SI 200630146T SI 200630146 T SI200630146 T SI 200630146T SI 1917254 T1 SI1917254 T1 SI 1917254T1
- Authority
- SI
- Slovenia
- Prior art keywords
- amorolfine
- producing
- producing amorolfine
- Prior art date
Links
- MQHLMHIZUIDKOO-OKZBNKHCSA-N (2R,6S)-2,6-dimethyl-4-[(2S)-2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine Chemical compound C1=CC(C(C)(C)CC)=CC=C1C[C@H](C)CN1C[C@@H](C)O[C@@H](C)C1 MQHLMHIZUIDKOO-OKZBNKHCSA-N 0.000 title 1
- 229960003204 amorolfine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05291612A EP1749825A1 (en) | 2005-07-28 | 2005-07-28 | Process of producing amorolfine |
| EP06809226A EP1917254B1 (en) | 2005-07-28 | 2006-07-27 | Process of producing amorolfine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1917254T1 true SI1917254T1 (sl) | 2009-04-30 |
Family
ID=35044548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630146T SI1917254T1 (sl) | 2005-07-28 | 2006-07-27 | Postopek izdelave amorolfina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090163711A1 (sl) |
| EP (2) | EP1749825A1 (sl) |
| JP (1) | JP2009502901A (sl) |
| AR (1) | AR057087A1 (sl) |
| AT (1) | ATE417839T1 (sl) |
| BR (1) | BRPI0606197B8 (sl) |
| CA (1) | CA2601149C (sl) |
| CY (1) | CY1108884T1 (sl) |
| DE (1) | DE602006004360D1 (sl) |
| DK (1) | DK1917254T3 (sl) |
| ES (1) | ES2319819T3 (sl) |
| PL (1) | PL1917254T3 (sl) |
| PT (1) | PT1917254E (sl) |
| SI (1) | SI1917254T1 (sl) |
| WO (1) | WO2007012983A2 (sl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1935889A1 (en) * | 2006-12-21 | 2008-06-25 | Galderma S.A. | Process of producing amorolfine |
| AU2009321601B2 (en) | 2008-12-04 | 2012-11-01 | F. Hoffmann-La Roche Ag | Pyridazinone derivatives |
| ITFI20090032A1 (it) | 2009-02-20 | 2010-08-21 | Synteco S P A Prodotti Di Sintesi Per L Ind | Processo di produzione industriale dell'amorolfina cloridrato |
| WO2011003455A1 (de) * | 2009-07-09 | 2011-01-13 | Cilag Ag | Verfahren zur herstellung von 4-(alkyl)-1-(2-methyl-3-(2,6-dimethylmorpholin)propyl) benzolverbindungen |
| WO2011066735A1 (en) * | 2009-12-01 | 2011-06-09 | Zhejiang Hisoar Pharmaceutical Co., Ltd | An Amorolfine HCl Crystal and the Preparation thereof |
| CN108997246B (zh) * | 2017-06-06 | 2021-08-31 | 江苏礼华生物技术有限公司 | 盐酸阿莫罗芬的制备方法 |
| CN109232458A (zh) * | 2018-06-15 | 2019-01-18 | 南通常佑药业科技有限公司 | 一种手性吗啉化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2965247D1 (en) * | 1978-08-08 | 1983-05-26 | Hoffmann La Roche | Synthesis of phenyl-propyl morpholine and piperidine derivatives |
| ZW15780A1 (en) | 1979-08-17 | 1981-03-18 | Hoffmann La Roche | Heterocyclic compounds |
| FR2589858A1 (fr) * | 1985-11-14 | 1987-05-15 | Exxon Production Research Co | Procede d'alkylation selective de composes aromatiques |
-
2005
- 2005-07-28 EP EP05291612A patent/EP1749825A1/en not_active Withdrawn
-
2006
- 2006-07-27 BR BRPI0606197A patent/BRPI0606197B8/pt active IP Right Grant
- 2006-07-27 ES ES06809226T patent/ES2319819T3/es active Active
- 2006-07-27 CA CA2601149A patent/CA2601149C/en not_active Expired - Fee Related
- 2006-07-27 JP JP2008523486A patent/JP2009502901A/ja not_active Withdrawn
- 2006-07-27 PT PT06809226T patent/PT1917254E/pt unknown
- 2006-07-27 WO PCT/IB2006/003210 patent/WO2007012983A2/en not_active Ceased
- 2006-07-27 DK DK06809226T patent/DK1917254T3/da active
- 2006-07-27 AT AT06809226T patent/ATE417839T1/de active
- 2006-07-27 EP EP06809226A patent/EP1917254B1/en active Active
- 2006-07-27 AR ARP060103246A patent/AR057087A1/es not_active Application Discontinuation
- 2006-07-27 PL PL06809226T patent/PL1917254T3/pl unknown
- 2006-07-27 US US11/795,033 patent/US20090163711A1/en not_active Abandoned
- 2006-07-27 SI SI200630146T patent/SI1917254T1/sl unknown
- 2006-07-27 DE DE602006004360T patent/DE602006004360D1/de active Active
-
2009
- 2009-03-17 CY CY20091100295T patent/CY1108884T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2601149C (en) | 2011-01-04 |
| PT1917254E (pt) | 2009-02-23 |
| DE602006004360D1 (de) | 2009-01-29 |
| ATE417839T1 (de) | 2009-01-15 |
| BRPI0606197A2 (pt) | 2009-06-02 |
| US20090163711A1 (en) | 2009-06-25 |
| JP2009502901A (ja) | 2009-01-29 |
| WO2007012983A3 (en) | 2007-05-03 |
| BRPI0606197B1 (pt) | 2021-03-30 |
| WO2007012983A2 (en) | 2007-02-01 |
| PL1917254T3 (pl) | 2009-06-30 |
| ES2319819T3 (es) | 2009-05-12 |
| BRPI0606197B8 (pt) | 2021-05-25 |
| CY1108884T1 (el) | 2014-07-02 |
| AR057087A1 (es) | 2007-11-14 |
| EP1749825A1 (en) | 2007-02-07 |
| CA2601149A1 (en) | 2007-02-01 |
| DK1917254T3 (da) | 2009-03-16 |
| EP1917254A2 (en) | 2008-05-07 |
| EP1917254B1 (en) | 2008-12-17 |
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