DK2929891T3 - Fremgangsmåde til modulering af appetitten - Google Patents
Fremgangsmåde til modulering af appetitten Download PDFInfo
- Publication number
- DK2929891T3 DK2929891T3 DK15163748.5T DK15163748T DK2929891T3 DK 2929891 T3 DK2929891 T3 DK 2929891T3 DK 15163748 T DK15163748 T DK 15163748T DK 2929891 T3 DK2929891 T3 DK 2929891T3
- Authority
- DK
- Denmark
- Prior art keywords
- modulating
- appearance
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/02—Nutritional disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/303—Eating disorders, e.g. anorexia, bulimia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004901957A AU2004901957A0 (en) | 2004-04-13 | Method for modulating appetite | |
| EP05729508.1A EP1734986B1 (en) | 2004-04-13 | 2005-04-13 | Method for modulating appetite |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2929891T3 true DK2929891T3 (da) | 2020-05-11 |
Family
ID=35149777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15163748.5T DK2929891T3 (da) | 2004-04-13 | 2005-04-13 | Fremgangsmåde til modulering af appetitten |
| DK11183884.3T DK2441466T3 (da) | 2004-04-13 | 2005-04-13 | MIC-1-inhiberende middel |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11183884.3T DK2441466T3 (da) | 2004-04-13 | 2005-04-13 | MIC-1-inhiberende middel |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US8192735B2 (da) |
| EP (4) | EP2441466B1 (da) |
| JP (4) | JP5448338B2 (da) |
| CA (2) | CA2905125C (da) |
| CY (1) | CY1115731T1 (da) |
| DK (2) | DK2929891T3 (da) |
| ES (3) | ES2555956T3 (da) |
| PL (2) | PL2929891T3 (da) |
| PT (2) | PT2441466E (da) |
| SI (1) | SI2441466T1 (da) |
| WO (1) | WO2005099746A1 (da) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2555956T3 (es) * | 2004-04-13 | 2016-01-11 | St Vincent's Hospital Sydney Limited | Método para modular el apetito |
| CA2660691C (en) * | 2006-08-04 | 2020-01-14 | Medizinische Hochschule Hannover | Means and methods for assessing the risk of cardiac interventions based on gdf-15 |
| WO2009021293A1 (en) * | 2007-08-16 | 2009-02-19 | St Vincent's Hospital Sydney Limited | Agents and methods for modulating macrophage inhibitory cytokine (mic-1) activity |
| JP2011502106A (ja) * | 2007-10-09 | 2011-01-20 | セントビンセンツ ホスピタル シドニー リミテッド | マクロファージ阻害性サイトカイン−1を除去又は不活性化して悪液質を治療する方法 |
| WO2010048670A1 (en) * | 2008-10-31 | 2010-05-06 | St Vincent's Hospital Sydney Limited | Method of prognosis in chronic kidney disease |
| MX343729B (es) * | 2011-04-08 | 2016-11-18 | Amgen Inc | Factor de diferenciación de crecimiento 15 (gdf-15) y composiciones del mismo para usarse en el tratamiento o mejoramiento de trastornos metabólicos. |
| MX2014009129A (es) | 2012-01-26 | 2014-11-21 | Amgen Inc | Polipeptidos de factor 15 de diferenciacion de crecimiento (gdf-15). |
| EP2830646B1 (en) * | 2012-03-27 | 2018-03-07 | NGM Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| EP3590537A1 (en) | 2012-09-26 | 2020-01-08 | Julius-Maximilians-Universität Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (gdf-15) |
| WO2014100689A1 (en) * | 2012-12-21 | 2014-06-26 | Aveo Pharmaceuticals, Inc. | Anti-gdf15 antibodies |
| US9161966B2 (en) | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
| US9828415B2 (en) | 2013-01-30 | 2017-11-28 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
| US9862752B2 (en) | 2013-07-31 | 2018-01-09 | Amgen Inc. | Growth differentiation factor 15 (GDF-15) constructs |
| GB2524552B (en) * | 2014-03-26 | 2017-07-12 | Julius-Maximilians-Universitãt Wurzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and use thereof for treating cancer |
| DK3122775T3 (da) | 2014-03-26 | 2020-02-03 | Univ Wuerzburg J Maximilians | Monoklonale antistoffer til vækst- og differentieringsfaktor 15 (gdf-15), og anvendelser deraf til behandling af cancer kakeksi og cancer |
| GB2524553C (en) * | 2014-03-26 | 2017-07-19 | Julius-Maximilians-Universitãt Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia |
| EP3157952B1 (en) * | 2014-06-20 | 2021-12-22 | Aveo Pharmaceuticals, Inc. | Treatment of congestive heart failure and other cardiac dysfunction using a gdf15 modulator |
| EP3157953B1 (en) * | 2014-06-20 | 2021-12-22 | Aveo Pharmaceuticals, Inc. | Treatment of chronic kidney disease and other renal dysfunction using a gdf15 modulator |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| EP3157942B1 (en) * | 2014-06-23 | 2020-06-17 | Novartis AG | Site specific protein modifications |
| WO2015197446A1 (en) | 2014-06-24 | 2015-12-30 | Novo Nordisk A/S | Mic-1 fusion proteins and uses thereof |
| JP6704358B2 (ja) | 2014-07-30 | 2020-06-03 | エヌジーエム バイオファーマシューティカルズ インコーポレイテッド | 代謝障害を治療するための組成物および使用方法 |
| EP3197493B1 (en) | 2014-09-25 | 2021-03-10 | Aveo Pharmaceuticals Inc. | Methods of reversing cachexia and prolonging survival comprising administering a gdf15 modulator and an anti-cancer agent |
| ES2799503T3 (es) | 2014-10-31 | 2020-12-18 | Ngm Biopharmaceuticals Inc | Composiciones y procedimientos de uso para el tratamiento de trastornos metabólicos |
| US20170334971A1 (en) * | 2014-12-22 | 2017-11-23 | Novo Nordisk A/S | Alpha-1-Antitrypsin (A1AT) Fusion Proteins and Uses Thereof |
| AU2016333538B2 (en) | 2015-10-02 | 2022-03-31 | Julius-Maximilians-Universität Würzburg | GDF-15 as a diagnostic marker to predict the clinical outcome of a treatment with immune checkpoint blockers |
| GB201517528D0 (en) | 2015-10-02 | 2015-11-18 | Julius Maximillians Universitãt Würzburg | GDF-15 as a diagnosis marker for melanoma |
| BR112018006218A2 (pt) | 2015-10-02 | 2018-10-09 | Univ Wuerzburg J Maximilians | iinibidores de hgdf-15, seus usos, composição, kit, combinações e método in vitro para determinar se uma substância de interesse é um inibidor de hgdf-15 |
| US11105818B2 (en) | 2016-01-15 | 2021-08-31 | Novo Nordisk A/S | MIC-1 receptor and uses thereof |
| US11604194B2 (en) | 2016-02-29 | 2023-03-14 | Public University Corporation Yokohama City University | Method for detecting castration-resistant prostate cancer and detection reagent |
| JP7021099B2 (ja) | 2016-03-31 | 2022-02-18 | エヌジーエム バイオファーマシューティカルス,インコーポレーテッド | 結合タンパク質及びその使用方法 |
| JP7138567B2 (ja) | 2016-04-27 | 2022-09-16 | ノバルティス アーゲー | 成長分化因子15に対する抗体およびそれらの使用 |
| PE20190117A1 (es) | 2016-05-24 | 2019-01-16 | Novo Nordisk As | Compuestos de mic-1 y usos de estos |
| JP2020503842A (ja) * | 2016-10-12 | 2020-02-06 | ヤンセン バイオテツク,インコーポレーテツド | Gdf15様生物活性の調節因子をスクリーニングするための方法 |
| CA3045700A1 (en) | 2016-12-06 | 2018-06-14 | St Vincent's Hospital Sydney Limited | Treatment of obesity and eating disorders |
| GB201700567D0 (en) | 2017-01-12 | 2017-03-01 | Genagon Therapeutics Ab | Therapeutic agents |
| TWI710377B (zh) | 2017-05-23 | 2020-11-21 | 丹麥商諾佛 儂迪克股份有限公司 | Mic-1化合物及其用途 |
| WO2019004550A1 (ko) * | 2017-06-26 | 2019-01-03 | 강원대학교 산학협력단 | Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도 |
| JP7127422B2 (ja) | 2017-08-30 | 2022-08-30 | 東ソー株式会社 | 癌を検出する方法及び検出試薬 |
| MA50233A (fr) | 2017-09-10 | 2020-07-22 | Novo Nordisk As | Mic-1 et glp-1 destinés à être utilisés dans le traitement de l'obésité |
| KR20200140878A (ko) | 2018-04-09 | 2020-12-16 | 암젠 인크 | 성장 분화 인자 15 융합 단백질 |
| KR102715542B1 (ko) | 2018-08-20 | 2024-10-08 | 화이자 인코포레이티드 | 항-gdf15 항체, 조성물 및 사용 방법 |
| US10706329B2 (en) * | 2018-11-13 | 2020-07-07 | CurieAI, Inc. | Methods for explainability of deep-learning models |
| AU2020394255A1 (en) | 2019-11-26 | 2022-06-09 | Yuhan Corporation | Long-acting GDF15 fusion protein and pharmaceutical composition comprising same |
| BR112023020152A2 (pt) | 2021-03-31 | 2023-11-14 | Cambridge Entpr Ltd | Inibidores terapêuticos de sinalização gdf15 |
| CA3219685A1 (en) | 2021-05-21 | 2022-11-24 | Seyoung LIM | Composition for preventing or treating non-alcoholic fatty liver disease or non-alcoholic steatohepatitis comprising growth differentiation factor-15 variant |
| WO2022245179A1 (en) | 2021-05-21 | 2022-11-24 | Yuhan Corporation | Composition for combination therapy comprising growth differentiation factor-15 variant and glucagon-like peptide-1 receptor agonist |
| US20250019427A1 (en) | 2021-08-10 | 2025-01-16 | Byomass Inc. | Anti-gdf15 antibodies, compositions and uses thereof |
| WO2023122213A1 (en) | 2021-12-22 | 2023-06-29 | Byomass Inc. | Targeting gdf15-gfral pathway cross-reference to related applications |
| WO2023154953A1 (en) | 2022-02-14 | 2023-08-17 | Ngm Biopharmaceuticals, Inc. | Gdf15 polypeptides for treating and preventing autoimmune diseases |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE69637844D1 (de) | 1995-06-22 | 2009-04-09 | St Vincent S Hospital Sidney L | Neues tgf-beta-ahnliches cytokin |
| WO1999006445A1 (en) | 1997-07-31 | 1999-02-11 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-15 |
| AU1103900A (en) | 1998-10-07 | 2000-04-26 | Stryker Corporation | Modified tgf-beta superfamily proteins |
| JP4920851B2 (ja) * | 2000-04-20 | 2012-04-18 | セイント ヴィンセンツ ホスピタル シドニー リミテッド | マクロファージ抑制サイトカイン−1(mic−1)が関連する検査方法 |
| AU2001288770A1 (en) * | 2000-09-08 | 2002-03-22 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | A non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties |
| US7157235B2 (en) * | 2002-06-17 | 2007-01-02 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
| ES2555956T3 (es) * | 2004-04-13 | 2016-01-11 | St Vincent's Hospital Sydney Limited | Método para modular el apetito |
| SI1844337T1 (sl) * | 2005-01-24 | 2013-11-29 | Pepscan Systems B.V. | Povezovalne spojine, imunogene spojine in peptidomimetiki |
| WO2010093925A2 (en) | 2009-02-12 | 2010-08-19 | Stryker Corporation | PERIPHERAL ADMINISTRATION OF PROTEINS INCLUDING TGF-β SUPERFAMILY MEMBERS FOR TREATMENT OF SYSTEMIC DISORDERS AND DISEASE |
-
2005
- 2005-04-13 ES ES05729508.1T patent/ES2555956T3/es not_active Expired - Lifetime
- 2005-04-13 US US11/547,675 patent/US8192735B2/en active Active
- 2005-04-13 DK DK15163748.5T patent/DK2929891T3/da active
- 2005-04-13 PT PT111838843T patent/PT2441466E/pt unknown
- 2005-04-13 PL PL15163748T patent/PL2929891T3/pl unknown
- 2005-04-13 EP EP11183884.3A patent/EP2441466B1/en not_active Expired - Lifetime
- 2005-04-13 PT PT151637485T patent/PT2929891T/pt unknown
- 2005-04-13 CA CA2905125A patent/CA2905125C/en not_active Expired - Lifetime
- 2005-04-13 EP EP15163748.5A patent/EP2929891B1/en not_active Expired - Lifetime
- 2005-04-13 ES ES15163748T patent/ES2788868T3/es not_active Expired - Lifetime
- 2005-04-13 SI SI200531902T patent/SI2441466T1/sl unknown
- 2005-04-13 EP EP05729508.1A patent/EP1734986B1/en not_active Expired - Lifetime
- 2005-04-13 EP EP14171119.2A patent/EP2774620A1/en not_active Withdrawn
- 2005-04-13 CA CA2561877A patent/CA2561877C/en not_active Expired - Lifetime
- 2005-04-13 PL PL11183884T patent/PL2441466T3/pl unknown
- 2005-04-13 ES ES11183884.3T patent/ES2518865T3/es not_active Expired - Lifetime
- 2005-04-13 JP JP2007507619A patent/JP5448338B2/ja not_active Expired - Lifetime
- 2005-04-13 DK DK11183884.3T patent/DK2441466T3/da active
- 2005-04-13 WO PCT/AU2005/000525 patent/WO2005099746A1/en not_active Ceased
-
2010
- 2010-11-05 US US12/926,272 patent/US8946146B2/en not_active Expired - Lifetime
-
2011
- 2011-04-08 JP JP2011086143A patent/JP2011190262A/ja active Pending
-
2013
- 2013-04-16 JP JP2013086022A patent/JP5767667B2/ja not_active Expired - Lifetime
- 2013-10-22 JP JP2013219147A patent/JP5806275B2/ja not_active Expired - Lifetime
-
2014
- 2014-10-22 CY CY20141100862T patent/CY1115731T1/el unknown
- 2014-12-22 US US14/578,611 patent/US20150183861A1/en not_active Abandoned
-
2016
- 2016-06-02 US US15/171,693 patent/US20160289320A1/en not_active Abandoned
-
2018
- 2018-06-11 US US16/004,519 patent/US20180346560A1/en not_active Abandoned
-
2020
- 2020-12-15 US US17/247,515 patent/US20210340243A1/en not_active Abandoned
-
2024
- 2024-05-10 US US18/660,675 patent/US20250109192A1/en active Pending
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