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DK1998750T3 - Mucosal bioadhæsiv bærer med langsom frigivelse til afgivelse af aktive stoffer - Google Patents

Mucosal bioadhæsiv bærer med langsom frigivelse til afgivelse af aktive stoffer

Info

Publication number
DK1998750T3
DK1998750T3 DK07734862.1T DK07734862T DK1998750T3 DK 1998750 T3 DK1998750 T3 DK 1998750T3 DK 07734862 T DK07734862 T DK 07734862T DK 1998750 T3 DK1998750 T3 DK 1998750T3
Authority
DK
Denmark
Prior art keywords
delivery
active substances
slow release
bioadhesive carrier
mucosal bioadhesive
Prior art date
Application number
DK07734862.1T
Other languages
English (en)
Inventor
Dominique Costantini
Caroline Lemarchand
Original Assignee
Bioalliance Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioalliance Pharma filed Critical Bioalliance Pharma
Application granted granted Critical
Publication of DK1998750T3 publication Critical patent/DK1998750T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK07734862.1T 2006-03-24 2007-03-23 Mucosal bioadhæsiv bærer med langsom frigivelse til afgivelse af aktive stoffer DK1998750T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06290480A EP1837020A1 (en) 2006-03-24 2006-03-24 Mucosal bioadhesive slow release carrier for delivering active principles
PCT/IB2007/001662 WO2007110778A2 (en) 2006-03-24 2007-03-23 Mucosal bioadhesive slow release carrier for delivering active principles

Publications (1)

Publication Number Publication Date
DK1998750T3 true DK1998750T3 (da) 2010-01-25

Family

ID=36889131

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07734862.1T DK1998750T3 (da) 2006-03-24 2007-03-23 Mucosal bioadhæsiv bærer med langsom frigivelse til afgivelse af aktive stoffer

Country Status (26)

Country Link
US (5) US20090169511A1 (da)
EP (3) EP1837020A1 (da)
JP (1) JP5242548B2 (da)
KR (1) KR101335185B1 (da)
CN (1) CN101410092B (da)
AR (1) AR060085A1 (da)
AT (1) ATE446743T1 (da)
AU (1) AU2007231029B2 (da)
BR (1) BRPI0709057C1 (da)
CA (1) CA2647123C (da)
CY (1) CY1109723T1 (da)
DE (1) DE602007002996D1 (da)
DK (1) DK1998750T3 (da)
ES (1) ES2335712T3 (da)
HR (1) HRP20100039T1 (da)
IL (1) IL193987A (da)
ME (1) ME01180B (da)
MX (1) MX2008012186A (da)
MY (1) MY150072A (da)
PL (1) PL1998750T3 (da)
PT (1) PT1998750E (da)
RS (1) RS51342B (da)
RU (1) RU2420267C2 (da)
SI (1) SI1998750T1 (da)
WO (1) WO2007110778A2 (da)
ZA (1) ZA200807883B (da)

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* Cited by examiner, † Cited by third party
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EP1837020A1 (en) 2006-03-24 2007-09-26 Bioalliance Pharma Mucosal bioadhesive slow release carrier for delivering active principles
EP2165706A1 (en) * 2008-09-18 2010-03-24 BioAlliance Pharma Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
EP2335690A1 (en) 2009-12-09 2011-06-22 BioAlliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes
TR201810146T4 (tr) * 2009-12-09 2018-08-27 Vectans Pharma Orofasiyal herpesin tedavisine yönelik mukoz yapışmalı ağız içi tabletleri.
US8592434B2 (en) 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
AU2012285969A1 (en) 2011-07-15 2014-01-30 Femalon S.P.R.L. Composition and method for treating HPV
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RU2631485C2 (ru) * 2012-02-19 2017-09-22 Орахэлс Корпорейшн Клейкое вещество на основе гуммиарабика, смешанное с карбонатом кальция, для пероральных прилипающих дисков
WO2016176396A1 (en) * 2015-04-29 2016-11-03 Foresight Biotherapeutics, Inc. Therapeutic combinations of antiviral and anti-inflammatory therapies
RU2636185C1 (ru) * 2016-08-03 2017-11-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) Способ лечения хронического генерализованного катарального гингивита в стадии обострения
RU2636173C1 (ru) * 2016-08-03 2017-11-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) Способ лечения хронического генерализованного пародонтита средней степени тяжести в стадии обострения
BR102018008324A2 (pt) * 2018-04-25 2019-11-05 Laboratorios Ferring Ltda composição farmacêutica de uso tópico e processo de fabricação de composição farmacêutica de uso tópico
MX2020011568A (es) * 2018-04-30 2020-11-24 Perfect Day Inc Polimeros de proteina de leche recombinante.
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation
CN111803468B (zh) * 2020-06-23 2022-12-23 黑龙江天龙药业有限公司 一种靶向、缓释、成膜抑制病毒、细菌的鼻腔喷膜剂及其制备方法
CN115463102B (zh) * 2022-09-26 2023-11-24 湖北科益药业股份有限公司 一种阿昔洛韦片剂及其制备方法

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Also Published As

Publication number Publication date
BRPI0709057A2 (pt) 2011-06-28
US8791127B2 (en) 2014-07-29
KR20090010958A (ko) 2009-01-30
US8211466B2 (en) 2012-07-03
BRPI0709057C1 (pt) 2021-05-25
US20100266667A1 (en) 2010-10-21
CN101410092B (zh) 2012-05-23
CA2647123A1 (en) 2007-10-04
SI1998750T1 (sl) 2010-02-26
BRPI0709057B8 (pt) 2021-02-23
EP1837020A1 (en) 2007-09-26
MY150072A (en) 2013-11-29
JP5242548B2 (ja) 2013-07-24
ATE446743T1 (de) 2009-11-15
ES2335712T3 (es) 2010-03-31
IL193987A (en) 2012-06-28
WO2007110778A2 (en) 2007-10-04
PT1998750E (pt) 2010-01-08
CY1109723T1 (el) 2014-08-13
RU2420267C2 (ru) 2011-06-10
AR060085A1 (es) 2008-05-21
CA2647123C (en) 2013-08-06
RU2008139869A (ru) 2010-04-27
ZA200807883B (en) 2011-02-23
US8747896B2 (en) 2014-06-10
AU2007231029B2 (en) 2012-02-02
EP2216017A1 (en) 2010-08-11
IL193987A0 (en) 2009-09-22
HK1121692A1 (en) 2009-04-30
EP1998750B1 (en) 2009-10-28
US20090169511A1 (en) 2009-07-02
MX2008012186A (es) 2009-01-16
RS51342B (sr) 2011-02-28
US20120326350A1 (en) 2012-12-27
KR101335185B1 (ko) 2013-12-02
CN101410092A (zh) 2009-04-15
US20120329817A1 (en) 2012-12-27
EP1998750A2 (en) 2008-12-10
DE602007002996D1 (de) 2009-12-10
HRP20100039T1 (hr) 2010-02-28
AU2007231029A1 (en) 2007-10-04
WO2007110778A3 (en) 2008-04-24
PL1998750T3 (pl) 2010-03-31
JP2009531411A (ja) 2009-09-03
ME01180B (me) 2013-03-20
BRPI0709057B1 (pt) 2020-06-30
US20130303556A1 (en) 2013-11-14

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